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Items: 47

1.

Rationale and Design for a GRADE Substudy of Continuous Glucose Monitoring.

Larkin ME, Nathan DM, Bebu I, Krause-Steinrauf H, Herman WH, Higgins JM, Tiktin M, Cohen RM, Lund C, Bergenstal RM, Johnson ML, Arends V; GRADE Research Group.

Diabetes Technol Ther. 2019 Sep 4. doi: 10.1089/dia.2019.0202. [Epub ahead of print]

PMID:
31393176
2.

Response to Comment on Braffett et al. Association of Insulin Dose, Cardiometabolic Risk Factors, and Cardiovascular Disease in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study. Diabetes Care 2019;42:657-664.

Braffett BH, Dagogo-Jack S, Bebu I, Sivitz WI, Larkin M, Kolterman O, Lachin JM; DCCT/EDIC Research Group.

Diabetes Care. 2019 Aug;42(8):e137. doi: 10.2337/dci19-0026. No abstract available.

PMID:
31332032
3.

Closed testing using surrogate hypotheses with restricted alternatives.

Lachin JM, Bebu I, Larsen MD, Younes N.

PLoS One. 2019 Jul 12;14(7):e0219520. doi: 10.1371/journal.pone.0219520. eCollection 2019.

4.

Immune Complexes and the Risk of CVD in Type 1 Diabetes.

Lopes-Virella MF, Bebu I, Hunt KJ, Virella G, Baker NL, Braffett B, Gao X, Lachin JM; DCCT/EDIC Research Group.

Diabetes. 2019 Sep;68(9):1853-1860. doi: 10.2337/db19-0358. Epub 2019 Jun 19.

PMID:
31217176
5.

Screening eye exams in youth with type 1 diabetes under 18 years of age: Once may be enough?

Gubitosi-Klug RA, Bebu I, White NH, Malone J, Miller R, Lorenzi GM, Hainsworth DP, Trapani VR, Lachin JM, Tamborlane WV; Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group*.

Pediatr Diabetes. 2019 Sep;20(6):743-749. doi: 10.1111/pedi.12877. Epub 2019 Jul 9.

PMID:
31206973
6.

Serum apolipoproteins and apolipoprotein-defined lipoprotein subclasses: a hypothesis-generating prospective study of cardiovascular events in T1D.

Basu A, Bebu I, Jenkins AJ, Stoner JA, Zhang Y, Klein RL, Lopes-Virella MF, Garvey WT, Budoff MJ, Alaupovic P, Lyons TJ; Diabetes Control Complications Trial/Epidemiology of Diabetes Interventions Complications Research Group.

J Lipid Res. 2019 Aug;60(8):1432-1439. doi: 10.1194/jlr.P090647. Epub 2019 Jun 15.

PMID:
31203233
7.

Early Glomerular Hyperfiltration and Long-Term Kidney Outcomes in Type 1 Diabetes: The DCCT/EDIC Experience.

Molitch ME, Gao X, Bebu I, de Boer IH, Lachin J, Paterson A, Perkins B, Saenger AK, Steffes M, Zinman B; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group.

Clin J Am Soc Nephrol. 2019 Jun 7;14(6):854-861. doi: 10.2215/CJN.14831218. Epub 2019 May 23.

PMID:
31123181
8.

Mediation of the Effect of Glycemia on the Risk of CVD Outcomes in Type 1 Diabetes: The DCCT/EDIC Study.

Bebu I, Braffett BH, Orchard TJ, Lorenzi GM, Lachin JM; DCCT/EDIC Research Group.

Diabetes Care. 2019 Jul;42(7):1284-1289. doi: 10.2337/dc18-1613. Epub 2019 Mar 20.

PMID:
30894365
9.

The Association of Coronary Artery Calcification With Subsequent Incidence of Cardiovascular Disease in Type 1 Diabetes: The DCCT/EDIC Trials.

Budoff M, Backlund JC, Bluemke DA, Polak J, Bebu I, Schade D, Strowig S, Raskin P, Lachin JM; DCCT/EDIC Research Group.

JACC Cardiovasc Imaging. 2019 Jul;12(7 Pt 2):1341-1349. doi: 10.1016/j.jcmg.2019.01.014. Epub 2019 Mar 13.

PMID:
30878435
10.

Risk Factors for Kidney Disease in Type 1 Diabetes.

Perkins BA, Bebu I, de Boer IH, Molitch M, Tamborlane W, Lorenzi G, Herman W, White NH, Pop-Busui R, Paterson AD, Orchard T, Cowie C, Lachin JM; Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group.

Diabetes Care. 2019 May;42(5):883-890. doi: 10.2337/dc18-2062. Epub 2019 Mar 4.

PMID:
30833370
11.

Risk Factors for Retinopathy in Type 1 Diabetes: The DCCT/EDIC Study.

Hainsworth DP, Bebu I, Aiello LP, Sivitz W, Gubitosi-Klug R, Malone J, White NH, Danis R, Wallia A, Gao X, Barkmeier AJ, Das A, Patel S, Gardner TW, Lachin JM; Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group.

Diabetes Care. 2019 May;42(5):875-882. doi: 10.2337/dc18-2308. Epub 2019 Mar 4.

PMID:
30833368
12.

Association of Insulin Dose, Cardiometabolic Risk Factors, and Cardiovascular Disease in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study.

Braffett BH, Dagogo-Jack S, Bebu I, Sivitz WI, Larkin M, Kolterman O, Lachin JM; DCCT/EDIC Research Group.

Diabetes Care. 2019 Apr;42(4):657-664. doi: 10.2337/dc18-1574. Epub 2019 Feb 6.

PMID:
30728218
13.

Properties of composite time to first event versus joint marginal analyses of multiple outcomes.

Bebu I, Lachin JM.

Stat Med. 2018 Nov 30;37(27):3918-3930. doi: 10.1002/sim.7849. Epub 2018 Jun 28.

PMID:
29956365
14.

Biomarkers of tubulointerstitial damage and function in type 1 diabetes.

de Boer IH, Gao X, Bebu I, Hoofnagle AN, Lachin JM, Paterson A, Perkins BA, Saenger AK, Steffes MW, Zinman B, Molitch ME.

BMJ Open Diabetes Res Care. 2017 Nov 14;5(1):e000461. doi: 10.1136/bmjdrc-2017-000461. eCollection 2017.

15.

Response to Comment on Lachin et al. Association of Glycemic Variability in Type 1 Diabetes With Progression of Microvascular Outcomes in the Diabetes Control and Complications Trial. Diabetes Care 2017;40:777-783.

Lachin JM, Bebu I, Bergenstal RM, Pop-Busui R, Service FJ, Zinman B, Nathan DM; DCCT/EDIC Research Group.

Diabetes Care. 2017 Nov;40(11):e165-e166. doi: 10.2337/dci17-0038. No abstract available.

16.

The relationship of blood glucose with cardiovascular disease is mediated over time by traditional risk factors in type 1 diabetes: the DCCT/EDIC study.

Bebu I, Braffett BH, Pop-Busui R, Orchard TJ, Nathan DM, Lachin JM; DCCT/EDIC Research Group.

Diabetologia. 2017 Oct;60(10):2084-2091. doi: 10.1007/s00125-017-4374-4. Epub 2017 Jul 16.

17.

Frequency of Evidence-Based Screening for Diabetic Retinopathy.

Nathan DM, Bebu I, Lachin JM.

N Engl J Med. 2017 Jul 13;377(2):195. doi: 10.1056/NEJMc1706322. No abstract available.

PMID:
28700836
18.

Refining Measurement of Hemoglobin A1c.

Sacks DB, Bebu I, Lachin JM.

Clin Chem. 2017 Sep;63(9):1433-1435. doi: 10.1373/clinchem.2016.268573. Epub 2017 Jun 20. No abstract available.

19.

Optimal screening schedules for disease progression with application to diabetic retinopathy.

Bebu I, Lachin JM.

Biostatistics. 2018 Jan 1;19(1):1-13. doi: 10.1093/biostatistics/kxx009.

20.

Frequency of Evidence-Based Screening for Retinopathy in Type 1 Diabetes.

DCCT/EDIC Research Group, Nathan DM, Bebu I, Hainsworth D, Klein R, Tamborlane W, Lorenzi G, Gubitosi-Klug R, Lachin JM.

N Engl J Med. 2017 Apr 20;376(16):1507-1516. doi: 10.1056/NEJMoa1612836.

21.

Association of Glycemic Variability in Type 1 Diabetes With Progression of Microvascular Outcomes in the Diabetes Control and Complications Trial.

Lachin JM, Bebu I, Bergenstal RM, Pop-Busui R, Service FJ, Zinman B, Nathan DM; DCCT/EDIC Research Group.

Diabetes Care. 2017 Jun;40(6):777-783. doi: 10.2337/dc16-2426. Epub 2017 Apr 12.

22.

Electrocardiographic Abnormalities and Cardiovascular Disease Risk in Type 1 Diabetes: The Epidemiology of Diabetes Interventions and Complications (EDIC) Study.

Soliman EZ, Backlund JC, Bebu I, Orchard TJ, Zinman B, Lachin JM; DCCT/EDIC Research Group.

Diabetes Care. 2017 Jun;40(6):793-799. doi: 10.2337/dc16-2050. Epub 2017 Mar 16.

23.

Tolerance limits and tolerance intervals for ratios of normal random variables using a bootstrap calibration.

Flouri M, Zhai S, Mathew T, Bebu I.

Biom J. 2017 May;59(3):550-566. doi: 10.1002/bimj.201600117. Epub 2017 Feb 9.

PMID:
28181281
24.

Albuminuria Changes and Cardiovascular and Renal Outcomes in Type 1 Diabetes: The DCCT/EDIC Study.

de Boer IH, Gao X, Cleary PA, Bebu I, Lachin JM, Molitch ME, Orchard T, Paterson AD, Perkins BA, Steffes MW, Zinman B; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group.

Clin J Am Soc Nephrol. 2016 Nov 7;11(11):1969-1977. Epub 2016 Oct 24.

25.

Significance of Epicardial and Intrathoracic Adipose Tissue Volume among Type 1 Diabetes Patients in the DCCT/EDIC: A Pilot Study.

Darabian S, Backlund JY, Cleary PA, Sheidaee N, Bebu I, Lachin JM, Budoff MJ; DCCT/EDIC Research Group.

PLoS One. 2016 Jul 26;11(7):e0159958. doi: 10.1371/journal.pone.0159958. eCollection 2016.

26.

Generalized Confidence Intervals and Fiducial Intervals for Some Epidemiological Measures.

Bebu I, Luta G, Mathew T, Agan BK.

Int J Environ Res Public Health. 2016 Jun 18;13(6). pii: E605. doi: 10.3390/ijerph13060605.

27.

Probabilistic measures of cost-effectiveness.

Bebu I, Mathew T, Lachin JM.

Stat Med. 2016 Sep 30;35(22):3976-86. doi: 10.1002/sim.6987. Epub 2016 May 18.

PMID:
27194076
28.

D-Dimer Levels before HIV Seroconversion Remain Elevated Even after Viral Suppression and Are Associated with an Increased Risk of Non-AIDS Events.

Freiberg MS, Bebu I, Tracy R, So-Armah K, Okulicz J, Ganesan A, Armstrong A, O'Bryan T, Rimland D, Justice AC, Agan BK; Infectious Disease Clinical Research Program HIV Working Group.

PLoS One. 2016 Apr 18;11(4):e0152588. doi: 10.1371/journal.pone.0152588. eCollection 2016.

29.

Progression of Electrocardiographic Abnormalities in Type 1 Diabetes During 16 Years of Follow-up: The Epidemiology of Diabetes Interventions and Complications (EDIC) Study.

Soliman EZ, Backlund JY, Bebu I, Li Y, Zhang ZM, Cleary PA, Lachin JM; DCCT/EDIC Research Group.

J Am Heart Assoc. 2016 Mar 14;5(3):e002882. doi: 10.1161/JAHA.115.002882.

30.

Characterizing the Association Between Alcohol and HIV Virologic Failure in a Military Cohort on Antiretroviral Therapy.

Deiss RG, Mesner O, Agan BK, Ganesan A, Okulicz JF, Bavaro M, Lalani T, O'Bryan TA, Bebu I, Macalino GE.

Alcohol Clin Exp Res. 2016 Mar;40(3):529-35. doi: 10.1111/acer.12975. Epub 2016 Feb 25.

31.

Testosterone and cardiac mass and function in men with type 1 diabetes in the Epidemiology of Diabetes Interventions and Complications Study (EDIC).

Kim C, Bebu I, Braffett B, Cleary PA, Arends V, Steffes M, Wessells H, Orchard T, Sarma AV; DCCT/EDIC Research Group.

Clin Endocrinol (Oxf). 2016 May;84(5):693-9. doi: 10.1111/cen.12990. Epub 2016 Jan 25.

32.

Testosterone Concentrations and Cardiovascular Autonomic Neuropathy in Men with Type 1 Diabetes in the Epidemiology of Diabetes Interventions and Complications Study (EDIC).

Kim C, Pop-Busui R, Braffett B, Cleary PA, Bebu I, Wessells H, Orchard T, Sarma AV; DCCT/E.D.I.C. Research Group.

J Sex Med. 2015 Nov;12(11):2153-9. doi: 10.1111/jsm.13029. Epub 2015 Nov 12.

33.

Large sample inference for a win ratio analysis of a composite outcome based on prioritized components.

Bebu I, Lachin JM.

Biostatistics. 2016 Jan;17(1):178-87. doi: 10.1093/biostatistics/kxv032. Epub 2015 Sep 8.

34.

Application of the Wei-Lachin multivariate one-directional test to multiple event-time outcomes.

Lachin JM, Bebu I.

Clin Trials. 2015 Dec;12(6):627-33. doi: 10.1177/1740774515601027. Epub 2015 Sep 2.

35.

Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation.

Zhang YW, Nasto RE, Varghese R, Jablonski SA, Serebriiskii IG, Surana R, Calvert VS, Bebu I, Murray J, Jin L, Johnson M, Riggins R, Ressom H, Petricoin E, Clarke R, Golemis EA, Weiner LM.

Oncogene. 2016 Mar 31;35(13):1643-56. doi: 10.1038/onc.2015.226. Epub 2015 Jul 13.

36.

Randomized, Double-Blind, Placebo-Controlled Study on Decolonization Procedures for Methicillin-Resistant Staphylococcus aureus (MRSA) among HIV-Infected Adults.

Weintrob A, Bebu I, Agan B, Diem A, Johnson E, Lalani T, Wang X, Bavaro M, Ellis M, Mende K, Crum-Cianflone N.

PLoS One. 2015 May 27;10(5):e0128071. doi: 10.1371/journal.pone.0128071. eCollection 2015.

37.

Inference for Surrogate Endpoint Validation in the Binary Case.

Bebu I, Mathew T, Agan B.

J Biopharm Stat. 2015;25(6):1272-84. doi: 10.1080/10543406.2015.1008516. Epub 2015 Jan 23.

PMID:
25616958
38.

Mediation analysis of gestational age, congenital heart defects, and infant birth-weight.

Wogu AF, Loffredo CA, Bebu I, Luta G.

BMC Res Notes. 2014 Dec 17;7:926. doi: 10.1186/1756-0500-7-926.

39.

HIV outcomes in Hepatitis B virus coinfected individuals on HAART.

Chun HM, Mesner O, Thio CL, Bebu I, Macalino G, Agan BK, Bradley WP, Malia J, Peel SA, Jagodzinski LL, Weintrob AC, Ganesan A, Bavaro M, Maguire JD, Landrum ML; Infectious Disease Clinical Research Program HIV Working Group.

J Acquir Immune Defic Syndr. 2014 Jun 1;66(2):197-205. doi: 10.1097/QAI.0000000000000142.

40.

Combining epidemiologic and biostatistical tools to enhance variable selection in HIV cohort analyses.

Rentsch C, Bebu I, Guest JL, Rimland D, Agan BK, Marconi V.

PLoS One. 2014 Jan 29;9(1):e87352. doi: 10.1371/journal.pone.0087352. eCollection 2014.

41.

The VACS index predicts mortality in a young, healthy HIV population starting highly active antiretroviral therapy.

Bebu I, Tate J, Rimland D, Mesner O, Macalino GE, Ganesan A, Okulicz JF, Bavaro M, Weintrob AC, Justice AC, Agan BK; Infectious Disease Clinical Research Program HIV Working Group.

J Acquir Immune Defic Syndr. 2014 Feb 1;65(2):226-30. doi: 10.1097/QAI.0000000000000045.

42.

Confidence intervals for confirmatory adaptive two-stage designs with treatment selection.

Bebu I, Dragalin V, Luta G.

Biom J. 2013 May;55(3):294-309. doi: 10.1002/bimj.201200053. Epub 2013 Apr 3.

PMID:
23553644
43.

Urinary estrogen metabolites and prostate cancer risk: a pilot study.

Kosti O, Xu X, Veenstra TD, Hsing AW, Chu LW, Goldman L, Bebu I, Collins S, Dritschilo A, Lynch JH, Goldman R.

Prostate. 2011 Apr;71(5):507-16. doi: 10.1002/pros.21262. Epub 2010 Sep 30.

44.

Likelihood inference for a two-stage design with treatment selection.

Bebu I, Luta G, Dragalin V.

Biom J. 2010 Dec;52(6):811-22. doi: 10.1002/bimj.200900170.

PMID:
20818645
45.

Microarray probes and probe sets.

Liu H, Bebu I, Li X.

Front Biosci (Elite Ed). 2010 Jan 1;2:325-38. Review.

46.

Generalized confidence intervals for ratios of regression coefficients with applications to bioassays.

Bebu I, Seillier-Moiseiwitsch F, Mathew T.

Biom J. 2009 Dec;51(6):1047-58. doi: 10.1002/bimj.200900038.

PMID:
19894218
47.

Comparing the means and variances of a bivariate log-normal distribution.

Bebu I, Mathew T.

Stat Med. 2008 Jun 30;27(14):2684-96.

PMID:
17907261

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