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Items: 21

1.

Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists.

Adlere I, Sun S, Zarca A, Roumen L, Gozelle M, Viciano CP, Caspar B, Arimont M, Bebelman JP, Briddon SJ, Hoffmann C, Hill SJ, Smit MJ, Vischer HF, Wijtmans M, de Graaf C, de Esch IJP, Leurs R.

Eur J Med Chem. 2019 Jan 15;162:631-649. doi: 10.1016/j.ejmech.2018.10.060. Epub 2018 Oct 30.

PMID:
30476826
2.

Photoswitching the Efficacy of a Small-Molecule Ligand for a Peptidergic GPCR: from Antagonism to Agonism.

Gómez-Santacana X, de Munnik SM, Vijayachandran P, Da Costa Pereira D, Bebelman JPM, de Esch IJP, Vischer HF, Wijtmans M, Leurs R.

Angew Chem Int Ed Engl. 2018 Sep 3;57(36):11608-11612. doi: 10.1002/anie.201804875. Epub 2018 Aug 6.

PMID:
29926530
3.

Surface plasmon resonance biosensor assay for the analysis of small-molecule inhibitor binding to human and parasitic phosphodiesterases.

Siderius M, Shanmugham A, England P, van der Meer T, Bebelman JP, Blaazer AR, de Esch IJ, Leurs R.

Anal Biochem. 2016 Jun 15;503:41-9. doi: 10.1016/j.ab.2016.03.013. Epub 2016 Mar 28.

PMID:
27033007
4.

The CXCR3-CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection.

Torraca V, Cui C, Boland R, Bebelman JP, van der Sar AM, Smit MJ, Siderius M, Spaink HP, Meijer AH.

Dis Model Mech. 2015 Mar;8(3):253-69. doi: 10.1242/dmm.017756. Epub 2015 Jan 8.

5.

Quantitative expression profiling of G-protein-coupled receptors (GPCRs) in metastatic melanoma: the constitutively active orphan GPCR GPR18 as novel drug target.

Qin Y, Verdegaal EM, Siderius M, Bebelman JP, Smit MJ, Leurs R, Willemze R, Tensen CP, Osanto S.

Pigment Cell Melanoma Res. 2011 Feb;24(1):207-18. doi: 10.1111/j.1755-148X.2010.00781.x. Epub 2010 Oct 21.

PMID:
20880198
6.

Cdc37p is involved in osmoadaptation and controls high osmolarity-induced cross-talk via the MAP kinase Kss1p.

Yang XX, Hawle P, Bebelman JP, Meenhuis A, Siderius M, van der Vies SM.

FEMS Yeast Res. 2007 Sep;7(6):796-807. Epub 2007 Apr 20.

7.

Thermosensitivity of the Saccharomyces cerevisiae gpp1gpp2 double deletion strain can be reduced by overexpression of genes involved in cell wall maintenance.

Wojda I, Bebelman JP, Jakubowicz T, Siderius M.

Arch Microbiol. 2007 Aug;188(2):175-84. Epub 2007 Mar 28.

PMID:
17390123
8.
9.
10.

Hyperosmotic stress response and regulation of cell wall integrity in Saccharomyces cerevisiae share common functional aspects.

Alonso-Monge R, Real E, Wojda I, Bebelman JP, Mager WH, Siderius M.

Mol Microbiol. 2001 Aug;41(3):717-30.

11.

Very low amounts of glucose cause repression of the stress-responsive gene HSP12 in Saccharomyces cerevisiae.

de Groot E, Bebelman JP, Mager WH, Planta RJ.

Microbiology. 2000 Feb;146 ( Pt 2):367-75.

PMID:
10708375
12.

Stp1p, Stp2p and Abf1p are involved in regulation of expression of the amino acid transporter gene BAP3 of Saccharomyces cerevisiae.

de Boer M, Nielsen PS, Bebelman JP, Heerikhuizen H, Andersen HA, Planta RJ.

Nucleic Acids Res. 2000 Feb 15;28(4):974-81.

13.

Regulation of expression of the amino acid transporter gene BAP3 in Saccharomyces cerevisiae.

De Boer M, Bebelman JP, Gonçalves PM, Maat J, Van Heerikhuizen H, Planta RJ.

Mol Microbiol. 1998 Nov;30(3):603-13.

14.

Signalling pathways leading to transcriptional regulation of genes involved in the activation of glycolysis in yeast.

Gonçalves PM, Griffioen G, Bebelman JP, Planta RJ.

Mol Microbiol. 1997 Aug;25(3):483-93.

15.

Transcription regulation of human and porcine pepsinogen A.

Pals G, Meijerink PH, Defize J, Bebelman JP, Strunk M, Arwert F, Timmerman A, Mager WH.

Adv Exp Med Biol. 1995;362:67-75. No abstract available.

PMID:
8540382
16.

Gastric chief cell-specific transcription of the pepsinogen A gene.

Meijerink PH, Bebelman JP, Oldenburg AM, Defize J, Planta RJ, Eriksson AW, Pals G, Mager WH.

Eur J Biochem. 1993 May 1;213(3):1283-96.

17.

Analysis of the promoter of a human pepsinogen A gene.

Meijerink PH, Bebelman JP, Pals G, Arwert F, Planta RJ, Eriksson AW, Mager WH.

Adv Exp Med Biol. 1991;306:87-90. No abstract available.

PMID:
1812762
18.

Family and population studies on the human pepsinogen A multigene family.

Bebelman JP, Evers MP, Zelle B, Bank R, Pronk JC, Meuwissen SG, Mager WH, Planta RJ, Eriksson AW, Frants RR.

Hum Genet. 1989 May;82(2):142-6.

PMID:
2566575
19.

Nucleotide sequence comparison of five human pepsinogen A (PGA) genes: evolution of the PGA multigene family.

Evers MP, Zelle B, Bebelman JP, van Beusechem V, Kraakman L, Hoffer MJ, Pronk JC, Mager WH, Planta RJ, Eriksson AW, et al.

Genomics. 1989 Apr;4(3):232-9.

PMID:
2714789
20.

Cloning and sequencing of rhesus monkey pepsinogen A cDNA.

Evers MP, Zelle B, Bebelman JP, Pronk JC, Mager WH, Planta RJ, Eriksson AW, Frants RR.

Gene. 1988 May 30;65(2):179-85.

PMID:
2900796
21.

Genomic structure and evolution of the human pepsinogen A multigene family.

Zelle B, Evers MP, Groot PC, Bebelman JP, Mager WH, Planta RJ, Pronk JC, Meuwissen SG, Hofker MH, Eriksson AW, et al.

Hum Genet. 1988 Jan;78(1):79-82.

PMID:
2892778

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