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Items: 10


VLA-4 phosphorylation during tumor and immune cell migration relies on its coupling to VEGFR2 and CXCR4 by syndecan-1.

Jung O, Beauvais DM, Adams KM, Rapraeger AC.

J Cell Sci. 2019 Sep 27. pii: jcs.232645. doi: 10.1242/jcs.232645. [Epub ahead of print]


Syndecan-1 (CD138) Suppresses Apoptosis in Multiple Myeloma by Activating IGF1 Receptor: Prevention by SynstatinIGF1R Inhibits Tumor Growth.

Beauvais DM, Jung O, Yang Y, Sanderson RD, Rapraeger AC.

Cancer Res. 2016 Sep 1;76(17):4981-93. doi: 10.1158/0008-5472.CAN-16-0232. Epub 2016 Jun 30.


Cytoplasmic domain interactions of syndecan-1 and syndecan-4 with α6β4 integrin mediate human epidermal growth factor receptor (HER1 and HER2)-dependent motility and survival.

Wang H, Jin H, Beauvais DM, Rapraeger AC.

J Biol Chem. 2014 Oct 31;289(44):30318-32. doi: 10.1074/jbc.M114.586438. Epub 2014 Sep 8.


Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation.

Beauvais DM, Rapraeger AC.

J Cell Sci. 2010 Nov 1;123(Pt 21):3796-807. doi: 10.1242/jcs.067645.


Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor.

Beauvais DM, Ell BJ, McWhorter AR, Rapraeger AC.

J Exp Med. 2009 Mar 16;206(3):691-705. doi: 10.1084/jem.20081278. Epub 2009 Mar 2.


Syndecan-1 regulates alphavbeta5 integrin activity in B82L fibroblasts.

McQuade KJ, Beauvais DM, Burbach BJ, Rapraeger AC.

J Cell Sci. 2006 Jun 15;119(Pt 12):2445-56. Epub 2006 May 23.


The syndecan-1 ectodomain regulates alphavbeta3 integrin activity in human mammary carcinoma cells.

Beauvais DM, Burbach BJ, Rapraeger AC.

J Cell Biol. 2004 Oct 11;167(1):171-81.


Syndecans in tumor cell adhesion and signaling.

Beauvais DM, Rapraeger AC.

Reprod Biol Endocrinol. 2004 Jan 7;2:3. Review.


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