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Items: 29


Sustained p16INK4a expression is required to prevent IR-induced tumorigenesis in mice.

Palacio L, Krishnan V, Le NL, Sharpless NE, Beauséjour CM.

Oncogene. 2017 Mar 2;36(9):1309-1314. doi: 10.1038/onc.2016.298. Epub 2016 Aug 29.


Heterotopic bone formation derived from multipotent stromal cells is not inhibited in aged mice.

Carbonneau CL, Despars G, Beaudry GM, Benabdallah B, Bouhanik S, Dépôt J, Moreau A, Beauséjour CM.

Cytotherapy. 2014 Aug;16(8):1073-9. doi: 10.1016/j.jcyt.2014.03.004. Epub 2014 Jun 13.


Expression of the senescence marker p16INK4a in skin biopsies of acute lymphoblastic leukemia survivors: a pilot study.

Marcoux S, Le ON, Langlois-Pelletier C, Laverdière C, Hatami A, Robaey P, Beauséjour CM.

Radiat Oncol. 2013 Oct 31;8:252. doi: 10.1186/1748-717X-8-252.


Loss of the osteogenic differentiation potential during senescence is limited to bone progenitor cells and is dependent on p53.

Despars G, Carbonneau CL, Bardeau P, Coutu DL, Beauséjour CM.

PLoS One. 2013 Aug 29;8(8):e73206. doi: 10.1371/journal.pone.0073206. eCollection 2013.


p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes.

Davalos AR, Kawahara M, Malhotra GK, Schaum N, Huang J, Ved U, Beausejour CM, Coppe JP, Rodier F, Campisi J.

J Cell Biol. 2013 May 13;201(4):613-29. doi: 10.1083/jcb.201206006. Epub 2013 May 6.


Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation.

Benabdallah BF, Duval A, Rousseau J, Chapdelaine P, Holmes MC, Haddad E, Tremblay JP, Beauséjour CM.

Mol Ther Nucleic Acids. 2013 Jan 29;2:e68. doi: 10.1038/mtna.2012.55.


A soluble granulocyte colony stimulating factor decoy receptor as a novel tool to increase hematopoietic cell homing and reconstitution in mice.

Fortin A, Benabdallah B, Palacio L, Carbonneau CL, Le ON, Haddad E, Beauséjour CM.

Stem Cells Dev. 2013 Mar 15;22(6):975-84. doi: 10.1089/scd.2012.0438. Epub 2013 Jan 11.


Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation.

Fumagalli M, Rossiello F, Clerici M, Barozzi S, Cittaro D, Kaplunov JM, Bucci G, Dobreva M, Matti V, Beausejour CM, Herbig U, Longhese MP, d'Adda di Fagagna F.

Nat Cell Biol. 2012 Mar 18;14(4):355-65. doi: 10.1038/ncb2466. Erratum in: Nat Cell Biol. 2012 May;14(5):555.


Ionizing radiation-induced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis.

Carbonneau CL, Despars G, Rojas-Sutterlin S, Fortin A, Le O, Hoang T, Beauséjour CM.

Blood. 2012 Jan 19;119(3):717-26. doi: 10.1182/blood-2011-06-361626. Epub 2011 Nov 18.


Therapeutic efficacy of cord blood-derived mesenchymal stromal cells for the prevention of acute graft-versus-host disease in a xenogenic mouse model.

Gregoire-Gauthier J, Selleri S, Fontaine F, Dieng MM, Patey N, Despars G, Beauséjour CM, Haddad E.

Stem Cells Dev. 2012 Jul 1;21(10):1616-26. doi: 10.1089/scd.2011.0413. Epub 2011 Oct 21.


DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion.

Rodier F, Muñoz DP, Teachenor R, Chu V, Le O, Bhaumik D, Coppé JP, Campeau E, Beauséjour CM, Kim SH, Davalos AR, Campisi J.

J Cell Sci. 2011 Jan 1;124(Pt 1):68-81. doi: 10.1242/jcs.071340. Epub 2010 Nov 30.


Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status.

Le ON, Rodier F, Fontaine F, Coppe JP, Campisi J, DeGregori J, Laverdière C, Kokta V, Haddad E, Beauséjour CM.

Aging Cell. 2010 Jun;9(3):398-409. doi: 10.1111/j.1474-9726.2010.00567.x. Epub 2010 Mar 13.


Targeted gene addition to human mesenchymal stromal cells as a cell-based plasma-soluble protein delivery platform.

Benabdallah BF, Allard E, Yao S, Friedman G, Gregory PD, Eliopoulos N, Fradette J, Spees JL, Haddad E, Holmes MC, Beauséjour CM.

Cytotherapy. 2010 May;12(3):394-9. doi: 10.3109/14653240903583803.


A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen.

Coppé JP, Patil CK, Rodier F, Krtolica A, Beauséjour CM, Parrinello S, Hodgson JG, Chin K, Desprez PY, Campisi J.

PLoS One. 2010 Feb 12;5(2):e9188. doi: 10.1371/journal.pone.0009188.


Secretion of SDF-1alpha by bone marrow-derived stromal cells enhances skin wound healing of C57BL/6 mice exposed to ionizing radiation.

Landry Y, Lê O, Mace KA, Restivo TE, Beauséjour CM.

J Cell Mol Med. 2010 Jun;14(6B):1594-604. doi: 10.1111/j.1582-4934.2009.00887.x. Epub 2009 Sep 1.


Blockade of sensory abnormalities and kinin B(1) receptor expression by N-acetyl-L-cysteine and ramipril in a rat model of insulin resistance.

Ismael MA, Talbot S, Carbonneau CL, Beauséjour CM, Couture R.

Eur J Pharmacol. 2008 Jul 28;589(1-3):66-72. doi: 10.1016/j.ejphar.2008.05.006. Epub 2008 May 16.


Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery.

Lombardo A, Genovese P, Beausejour CM, Colleoni S, Lee YL, Kim KA, Ando D, Urnov FD, Galli C, Gregory PD, Holmes MC, Naldini L.

Nat Biotechnol. 2007 Nov;25(11):1298-306. Epub 2007 Oct 28.


An improved zinc-finger nuclease architecture for highly specific genome editing.

Miller JC, Holmes MC, Wang J, Guschin DY, Lee YL, Rupniewski I, Beausejour CM, Waite AJ, Wang NS, Kim KA, Gregory PD, Pabo CO, Rebar EJ.

Nat Biotechnol. 2007 Jul;25(7):778-85. Epub 2007 Jul 1.


Ageing: balancing regeneration and cancer.

Beausejour CM, Campisi J.

Nature. 2006 Sep 28;443(7110):404-5. No abstract available.


Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence.

Coppé JP, Kauser K, Campisi J, Beauséjour CM.

J Biol Chem. 2006 Oct 6;281(40):29568-74. Epub 2006 Jul 31.


Highly efficient endogenous human gene correction using designed zinc-finger nucleases.

Urnov FD, Miller JC, Lee YL, Beausejour CM, Rock JM, Augustus S, Jamieson AC, Porteus MH, Gregory PD, Holmes MC.

Nature. 2005 Jun 2;435(7042):646-51. Epub 2005 Apr 3.


Reversal of human cellular senescence: roles of the p53 and p16 pathways.

Beauséjour CM, Krtolica A, Galimi F, Narita M, Lowe SW, Yaswen P, Campisi J.

EMBO J. 2003 Aug 15;22(16):4212-22.


Cytotoxic activity of 2',2'-difluorodeoxycytidine, 5-aza-2'-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene.

Beauséjour CM, Gagnon J, Primeau M, Momparler RL.

Biochem Biophys Res Commun. 2002 May 24;293(5):1478-84.


Human cytidine deaminase as an ex vivo drug selectable marker in gene-modified primary bone marrow stromal cells.

Eliopoulos N, Al-Khaldi A, Beauséjour CM, Momparler RL, Momparler LF, Galipeau J.

Gene Ther. 2002 Apr;9(7):452-62.


Selection of drug-resistant transduced cells with cytosine nucleoside analogs using the human cytidine deaminase gene.

Beauséjour CM, Eliopoulos N, Momparler L, Le NL, Momparler RL.

Cancer Gene Ther. 2001 Sep;8(9):669-76.


Potential of ribozymes against deoxycytidine kinase to confer drug resistance to cytosine nucleoside analogs.

Beauséjour CM, Tremblay G, Momparler RL.

Biochem Biophys Res Commun. 2000 Nov 30;278(3):569-75.


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