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Usefulness of Left Ventricular Assist Device in the Recovery of Severe Amphetamine-Associated Dilated Cardiomyopathy.

Soucy-Giguère MC, Cinq-Mars A, Charbonneau É, Voisine P, Beaudoin J, Dubois M, Sénéchal M.

Can J Cardiol. 2019 Oct 12. pii: S0828-282X(19)31340-6. doi: 10.1016/j.cjca.2019.09.024. [Epub ahead of print]


Airway smooth muscle adapting in dynamic conditions is refractory to the bronchodilator effect of a deep inspiration.

Gazzola M, Khadangi F, Clisson M, Beaudoin J, Clavel MA, Bossé Y.

Am J Physiol Lung Cell Mol Physiol. 2020 Jan 8. doi: 10.1152/ajplung.00270.2019. [Epub ahead of print]


Transesophageal echocardiography complications associated with interventional cardiology procedures.

Freitas-Ferraz AB, Rodés-Cabau J, Junquera Vega L, Beaudoin J, O'Connor K, Turgeon PY, Paradis JM, Ferreira-Neto A, Asmarats L, Champagne J, O'Hara G, Bernier M.

Am Heart J. 2019 Dec 9;221:19-28. doi: 10.1016/j.ahj.2019.11.018. [Epub ahead of print]


Dichotomic effects of clinically used drugs on tumor growth, bone remodeling and pain management.

André Barrière D, Midavaine É, Doré-Savard L, Kirby K, Tremblay L, Beaudoin JF, Beaudet N, Longpré JM, Lecomte R, Lepage M, Sarret P.

Sci Rep. 2019 Dec 27;9(1):20155. doi: 10.1038/s41598-019-56622-5.


Effects of the loss of estrogen on the heart's hypertrophic response to chronic left ventricle volume overload in rats.

Walsh-Wilkinson E, Beaumont C, Drolet MC, Roy ÈM, Le Houillier C, Beaudoin J, Arsenault M, Couet J.

PeerJ. 2019 Oct 21;7:e7924. doi: 10.7717/peerj.7924. eCollection 2019.


Shortening of airway smooth muscle is modulated by prolonging the time without simulated deep inspirations in ovine tracheal strips.

Gazzola M, Khadangi F, Clisson M, Beaudoin J, Clavel MA, Bossé Y.

J Appl Physiol (1985). 2019 Dec 1;127(6):1528-1538. doi: 10.1152/japplphysiol.00423.2019. Epub 2019 Sep 23.


Early Experience With Transcatheter Mitral Valve Replacement: A Systematic Review.

Del Val D, Ferreira-Neto AN, Wintzer-Wehekind J, Dagenais F, Paradis JM, Bernier M, O'Connor K, Beaudoin J, Freitas-Ferraz AB, Rodés-Cabau J.

J Am Heart Assoc. 2019 Sep 3;8(17):e013332. doi: 10.1161/JAHA.119.013332. Epub 2019 Aug 23.


Sex-Related Differences in the Extent of Myocardial Fibrosis in Patients With Aortic Valve Stenosis.

Tastet L, Kwiecinski J, Pibarot P, Capoulade R, Everett RJ, Newby DE, Shen M, Guzzetti E, Arsenault M, Bédard É, Larose É, Beaudoin J, Dweck M, Clavel MA.

JACC Cardiovasc Imaging. 2019 Aug 14. pii: S1936-878X(19)30596-0. doi: 10.1016/j.jcmg.2019.06.014. [Epub ahead of print]


Staging Cardiac Damage in Patients With Asymptomatic Aortic Valve Stenosis.

Tastet L, Tribouilloy C, Maréchaux S, Vollema EM, Delgado V, Salaun E, Shen M, Capoulade R, Clavel MA, Arsenault M, Bédard É, Bernier M, Beaudoin J, Narula J, Lancellotti P, Bax JJ, Généreux P, Pibarot P.

J Am Coll Cardiol. 2019 Jul 30;74(4):550-563. doi: 10.1016/j.jacc.2019.04.065.


Genome wide analysis of 3' UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish.

Vejnar CE, Abdel Messih M, Takacs CM, Yartseva V, Oikonomou P, Christiano R, Stoeckius M, Lau S, Lee MT, Beaudoin JD, Musaev D, Darwich-Codore H, Walther TC, Tavazoie S, Cifuentes D, Giraldez AJ.

Genome Res. 2019 Jul;29(7):1100-1114. doi: 10.1101/gr.245159.118. Epub 2019 Jun 21.


Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation.

Chan SH, Tang Y, Miao L, Darwich-Codore H, Vejnar CE, Beaudoin JD, Musaev D, Fernandez JP, Benitez MDJ, Bazzini AA, Moreno-Mateos MA, Giraldez AJ.

Dev Cell. 2019 Jun 17;49(6):867-881.e8. doi: 10.1016/j.devcel.2019.05.037.


Clinical and echocardiographic presentation of postmyocardial infarction papillary muscle rupture.

Leroux É, Chauvette V, Voisine P, Dagenais F, Charbonneau É, Beaudoin J, Dubois-Sénéchal É, Dubois M, Sénéchal M.

Echocardiography. 2019 Jul;36(7):1322-1329. doi: 10.1111/echo.14402. Epub 2019 Jun 17.


Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease.

Bezençon J, Beaudoin JJ, Ito K, Fu D, Roth SE, Brock WJ, Brouwer KLR.

Drug Metab Dispos. 2019 Aug;47(8):899-906. doi: 10.1124/dmd.119.086785. Epub 2019 Jun 3.


Testosterone deficiency reduces cardiac hypertrophy in a rat model of severe volume overload.

Beaumont C, Walsh-Wilkinson É, Drolet MC, Roussel É, Melançon N, Fortier É, Harpin G, Beaudoin J, Arsenault M, Couet J.

Physiol Rep. 2019 May;7(9):e14088. doi: 10.14814/phy2.14088.


Case report of an unusual and catastrophic presentation of coral reef aorta.

Verreault-Julien L, Beaudoin J, Thériault MM, Do DH.

Eur Heart J Case Rep. 2019 Jan 8;3(1):yty163. doi: 10.1093/ehjcr/yty163. eCollection 2019 Mar.


Growing Pigs' Interest in Enrichment Objects with Different Characteristics and Cleanliness.

Beaudoin JM, Bergeron R, Devillers N, Laforest JP.

Animals (Basel). 2019 Mar 8;9(3). pii: E85. doi: 10.3390/ani9030085.


Significant mitral regurgitation in patients undergoing TAVR: Mechanisms and imaging variables associated with improvement.

Chiche O, Rodés-Cabau J, Campelo-Parada F, Freitas-Ferraz AB, Regueiro A, Chamandi C, Rodriguez-Gabella T, Côté M, DeLarochellière R, Paradis JM, Dumont E, Doyle D, Mohammadi S, Bergeron S, Pibarot P, Beaudoin J.

Echocardiography. 2019 Apr;36(4):722-731. doi: 10.1111/echo.14303. Epub 2019 Mar 4.


Strain overestimates non-viable myocardium in patients with ischemic mitral regurgitation: understandable discrepancy of complementary methods?

Beaudoin J, Sénéchal M.

J Thorac Dis. 2018 Nov;10(Suppl 33):S3946-S3950. doi: 10.21037/jtd.2018.09.69. No abstract available.


Altered Hepatobiliary Disposition of Tolvaptan and Selected Tolvaptan Metabolites in a Rodent Model of Polycystic Kidney Disease.

Beaudoin JJ, Bezençon J, Cao Y, Mizuno K, Roth SE, Brock WJ, Brouwer KLR.

Drug Metab Dispos. 2019 Feb;47(2):155-163. doi: 10.1124/dmd.118.083907. Epub 2018 Nov 30. Erratum in: Drug Metab Dispos. 2019 Mar;47(3):328.


Novel in Vitro Method Reveals Drugs That Inhibit Organic Solute Transporter Alpha/Beta (OSTα/β).

Malinen MM, Kauttonen A, Beaudoin JJ, Sjöstedt N, Honkakoski P, Brouwer KLR.

Mol Pharm. 2019 Jan 7;16(1):238-246. doi: 10.1021/acs.molpharmaceut.8b00966. Epub 2018 Dec 14.


Co-delivery of paclitaxel and cisplatin in poly(2-oxazoline) polymeric micelles: Implications for drug loading, release, pharmacokinetics and outcome of ovarian and breast cancer treatments.

Wan X, Beaudoin JJ, Vinod N, Min Y, Makita N, Bludau H, Jordan R, Wang A, Sokolsky M, Kabanov AV.

Biomaterials. 2019 Feb;192:1-14. doi: 10.1016/j.biomaterials.2018.10.032. Epub 2018 Oct 31.


Second Time's a Charm: Percutaneous Edge-to-Edge Repair With the MitraClip Device as Rescue Therapy After a Failed Surgical Edge-to-Edge Alfieri Stitch.

Rimac G, Kalavrouziotis D, Beaudoin J, Rodés-Cabau J, Paradis JM.

Can J Cardiol. 2018 Sep;34(9):1233.e1-1233.e3. doi: 10.1016/j.cjca.2018.05.004. Epub 2018 May 9.


A role for the transcription factor Mca1 in activating the meiosis-specific copper transporter Mfc1.

Beaudoin J, Ioannoni R, Normant V, Labbé S.

PLoS One. 2018 Aug 7;13(8):e0201861. doi: 10.1371/journal.pone.0201861. eCollection 2018.


Analyses of mRNA structure dynamics identify embryonic gene regulatory programs.

Beaudoin JD, Novoa EM, Vejnar CE, Yartseva V, Takacs CM, Kellis M, Giraldez AJ.

Nat Struct Mol Biol. 2018 Aug;25(8):677-686. doi: 10.1038/s41594-018-0091-z. Epub 2018 Jul 30.


Hemodynamic impact of percutaneous left atrial appendage closure in patients with paroxysmal atrial fibrillation.

Asmarats L, Bernier M, O'Hara G, Paradis JM, O'Connor K, Beaudoin J, Bilodeau S, Cavalcanti R, Champagne J, Rodés-Cabau J.

J Interv Card Electrophysiol. 2018 Nov;53(2):151-157. doi: 10.1007/s10840-018-0387-2. Epub 2018 Jun 4.


Infective endocarditis following transcatheter edge-to-edge mitral valve repair: A systematic review.

Asmarats L, Rodriguez-Gabella T, Chamandi C, Bernier M, Beaudoin J, O'Connor K, Dumont E, Dagenais F, Paradis JM, Rodés-Cabau J.

Catheter Cardiovasc Interv. 2018 Sep 1;92(3):583-591. doi: 10.1002/ccd.27632. Epub 2018 May 10.


Bile Acids as Potential Biomarkers to Assess Liver Impairment in Polycystic Kidney Disease.

Brock WJ, Beaudoin JJ, Slizgi JR, Su M, Jia W, Roth SE, Brouwer KLR.

Int J Toxicol. 2018 Mar/Apr;37(2):144-154. doi: 10.1177/1091581818760746.


ApoB/ApoA-I Ratio is Associated With Faster Hemodynamic Progression of Aortic Stenosis: Results From the PROGRESSA (Metabolic Determinants of the Progression of Aortic Stenosis) Study.

Tastet L, Capoulade R, Shen M, Clavel MA, Côté N, Mathieu P, Arsenault M, Bédard É, Tremblay A, Samson M, Bossé Y, Dumesnil JG, Arsenault BJ, Beaudoin J, Bernier M, Després JP, Pibarot P.

J Am Heart Assoc. 2018 Feb 10;7(4). pii: e007980. doi: 10.1161/JAHA.117.007980.


Increasing Pulmonary Arterial Pressure at Low Level of Exercise in Asymptomatic, Organic Mitral Regurgitation.

Toubal O, Mahjoub H, Thébault C, Clavel MA, Dahou A, Magne J, O'Connor K, Beaudoin J, Bernier M, Le Ven F, Pibarot P.

J Am Coll Cardiol. 2018 Feb 13;71(6):700-701. doi: 10.1016/j.jacc.2017.11.062. No abstract available.


Organic solute transporter OSTα/β is overexpressed in nonalcoholic steatohepatitis and modulated by drugs associated with liver injury.

Malinen MM, Ali I, Bezençon J, Beaudoin JJ, Brouwer KLR.

Am J Physiol Gastrointest Liver Physiol. 2018 May 1;314(5):G597-G609. doi: 10.1152/ajpgi.00310.2017. Epub 2018 Feb 8.


Interaction between the patatin-like phospholipase domain-containing protein 3 genotype and coffee drinking and the risk for acute alcoholic hepatitis.

Liangpunsakul S, Beaudoin JJ, Shah VH, Puri P, Sanyal AJ, Kamath PS, Lourens SG, Tang Q, Katz BP, Crabb DW, Chalasani NP.

Hepatol Commun. 2017 Nov 11;2(1):29-34. doi: 10.1002/hep4.1123. eCollection 2018 Jan.


Adverse impact of diabetes mellitus on left ventricular remodelling in patients with chronic primary mitral regurgitation.

Ernande L, Beaudoin J, Piro V, Meziani S, Scherrer-Crosbie M.

Arch Cardiovasc Dis. 2018 Aug - Sep;111(8-9):487-496. doi: 10.1016/j.acvd.2017.10.004. Epub 2018 Jan 3.


Giant Left Atrial Appendage Aneurysm Mimicking Mediastinal Mass and Associated with Incessant Atrial Arrhythmias.

Morin J, Cantin L, Pasian S, Philippon F, Beaudoin J.

J Atr Fibrillation. 2017 Apr 30;9(6):1539. doi: 10.4022/jafib.1539. eCollection 2017 Apr-May.


Early Activation of Growth Pathways in Mitral Leaflets Exposed to Aortic Regurgitation: New Insights from an Animal Model.

Marsit O, Royer O, Drolet MC, Arsenault M, Couet J, Morin S, Levine RA, Pibarot P, Beaudoin J.

J Heart Valve Dis. 2017 May;26(3):281-289.


Forward Left Ventricular Ejection Fraction: A Simple Risk Marker in Patients With Primary Mitral Regurgitation.

Dupuis M, Mahjoub H, Clavel MA, Côté N, Toubal O, Tastet L, Dumesnil JG, O'Connor K, Dahou A, Thébault C, Bélanger C, Beaudoin J, Arsenault M, Bernier M, Pibarot P.

J Am Heart Assoc. 2017 Oct 27;6(11). pii: e006309. doi: 10.1161/JAHA.117.006309.


Mitral Leaflet Changes Following Myocardial Infarction: Clinical Evidence for Maladaptive Valvular Remodeling.

Beaudoin J, Dal-Bianco JP, Aikawa E, Bischoff J, Guerrero JL, Sullivan S, Bartko PE, Handschumacher MD, Kim DH, Wylie-Sears J, Aaron J, Levine RA.

Circ Cardiovasc Imaging. 2017 Nov;10(11). pii: e006512. doi: 10.1161/CIRCIMAGING.117.006512.


Multi-Modality Imaging in the Evaluation and Treatment of Mitral Regurgitation.

Bouchard MA, Côté-Laroche C, Beaudoin J.

Curr Treat Options Cardiovasc Med. 2017 Oct 13;19(12):91. doi: 10.1007/s11936-017-0589-4. Review.


The loss of P2X7 receptor expression leads to increase intestinal glucose transit and hepatic steatosis.

Arguin G, Bourzac JF, Placet M, Molle CM, Paquette M, Beaudoin JF, Rousseau JA, Lecomte R, Plourde M, Gendron FP.

Sci Rep. 2017 Oct 10;7(1):12917. doi: 10.1038/s41598-017-13300-8.


Association of Paravalvular Regurgitation With 1-Year Outcomes After Transcatheter Aortic Valve Replacement With the SAPIEN 3 Valve.

Pibarot P, Hahn RT, Weissman NJ, Arsenault M, Beaudoin J, Bernier M, Dahou A, Khalique OK, Asch FM, Toubal O, Leipsic J, Blanke P, Zhang F, Parvataneni R, Alu M, Herrmann H, Makkar R, Mack M, Smalling R, Leon M, Thourani VH, Kodali S.

JAMA Cardiol. 2017 Nov 1;2(11):1208-1216. doi: 10.1001/jamacardio.2017.3425.


Effect of Losartan on Mitral Valve Changes After Myocardial Infarction.

Bartko PE, Dal-Bianco JP, Guerrero JL, Beaudoin J, Szymanski C, Kim DH, Seybolt MM, Handschumacher MD, Sullivan S, Garcia ML, Titus JS, Wylie-Sears J, Irvin WS, Messas E, Hagège AA, Carpentier A, Aikawa E, Bischoff J, Levine RA; Leducq Transatlantic Mitral Network.

J Am Coll Cardiol. 2017 Sep 5;70(10):1232-1244. doi: 10.1016/j.jacc.2017.07.734.


An exploratory genome-wide analysis of genetic risk for alcoholic hepatitis.

Beaudoin JJ, Long N, Liangpunsakul S, Puri P, Kamath PS, Shah V, Sanyal AJ, Crabb DW, Chalasani NP, Urban TJ; TREAT Consortium.

Scand J Gastroenterol. 2017 Nov;52(11):1263-1269. doi: 10.1080/00365521.2017.1359664. Epub 2017 Aug 4.


Schizosaccharomyces pombe Grx4 regulates the transcriptional repressor Php4 via [2Fe-2S] cluster binding.

Dlouhy AC, Beaudoin J, Labbé S, Outten CE.

Metallomics. 2017 Aug 16;9(8):1096-1105. doi: 10.1039/c7mt00144d.


Changes in Coagulation and Platelet Activation Markers Following Transcatheter Left Atrial Appendage Closure.

Rodés-Cabau J, O'Hara G, Paradis JM, Bernier M, Rodriguez-Gabella T, Regueiro A, O'Connor K, Beaudoin J, Puri R, Côté M, Champagne J.

Am J Cardiol. 2017 Jul 1;120(1):87-91. doi: 10.1016/j.amjcard.2017.03.253. Epub 2017 Apr 12.


Current Management of Patients with Severe Aortic Regurgitation.

Nadeau-Routhier C, Marsit O, Beaudoin J.

Curr Treat Options Cardiovasc Med. 2017 Feb;19(2):9. doi: 10.1007/s11936-017-0508-8. Review.


Impact of left ventricular remodelling patterns on outcomes in patients with aortic stenosis.

Capoulade R, Clavel MA, Le Ven F, Dahou A, Thébault C, Tastet L, Shen M, Arsenault M, Bédard É, Beaudoin J, O'Connor K, Bernier M, Dumesnil JG, Pibarot P.

Eur Heart J Cardiovasc Imaging. 2017 Dec 1;18(12):1378-1387. doi: 10.1093/ehjci/jew288.


Distinct responses of compartmentalized glutathione redox potentials to pharmacologic quinones targeting NQO1.

Kolossov VL, Ponnuraj N, Beaudoin JN, Leslie MT, Kenis PJ, Gaskins HR.

Biochem Biophys Res Commun. 2017 Jan 29;483(1):680-686. doi: 10.1016/j.bbrc.2016.12.082. Epub 2016 Dec 14.


Run With the Hare and Hunt With the Hounds: Watchman Device Surgical Resection in the Setting of Recurrent Device Related Thrombi in a Patient With Bleeding Diathesis.

O'Hara C, O'Hara GE, Jacques F, Champagne J, Lemyre M, Charbonneau L, O'Connor K, Bernier M, Beaudoin J, Rodés-Cabau J, Paradis JM.

JACC Cardiovasc Interv. 2016 Dec 12;9(23):e223-e225. doi: 10.1016/j.jcin.2016.09.041. No abstract available.


Tyrosine kinase fusion genes in pediatric BCR-ABL1-like acute lymphoblastic leukemia.

Boer JM, Steeghs EM, Marchante JR, Boeree A, Beaudoin JJ, Beverloo HB, Kuiper RP, Escherich G, van der Velden VH, van der Schoot CE, de Groot-Kruseman HA, Pieters R, den Boer ML.

Oncotarget. 2017 Jan 17;8(3):4618-4628. doi: 10.18632/oncotarget.13492.


Left atrial appendage closure: Initial experience with the ultraseal device.

Regueiro A, Bernier M, O'Hara G, O'Connor K, Paradis JM, Beaudoin J, Rodriguez-Gabella T, Champagne J, Rodés-Cabau J.

Catheter Cardiovasc Interv. 2017 Nov 1;90(5):817-823. doi: 10.1002/ccd.26870. Epub 2016 Nov 17.


Impact of AVR on LV Remodeling and Function in Paradoxical Low-Flow, Low-Gradient Aortic Stenosis With Preserved LVEF.

Dahou A, Clavel MA, Dumesnil JG, Capoulade R, Ribeiro HB, O'Connor K, Mathieu P, Beaudoin J, Larose É, Rodés-Cabau J, Pibarot P.

JACC Cardiovasc Imaging. 2017 Jan;10(1):88-89. doi: 10.1016/j.jcmg.2016.07.009. Epub 2016 Nov 9. No abstract available.

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