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Items: 1 to 50 of 125

1.

Impact of the Microbiome on the Human Genome.

Jeyakumar T, Beauchemin N, Gros P.

Trends Parasitol. 2019 Oct;35(10):809-821. doi: 10.1016/j.pt.2019.07.015. Epub 2019 Aug 23. Review.

PMID:
31451407
2.

LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis.

Poffenberger MC, Metcalfe-Roach A, Aguilar E, Chen J, Hsu BE, Wong AH, Johnson RM, Flynn B, Samborska B, Ma EH, Gravel SP, Tonelli L, Devorkin L, Kim P, Hall A, Izreig S, Loginicheva E, Beauchemin N, Siegel PM, Artyomov MN, Lum JJ, Zogopoulos G, Blagih J, Jones RG.

Science. 2018 Jul 27;361(6400):406-411. doi: 10.1126/science.aan3975.

PMID:
30049881
3.

[Delivery in hypoxic tumor regions of a chemotherapeutic agent encapsulated in nanoliposomes carried by magnetoaerotactic bacteria].

Felfoul O, Mohammadi M, Taherkhani S, de Lanauze D, Zhong Xu Y, Lafleur M, Gaboury L, Tabrizian M, Vuong T, Batist G, Beauchemin N, Radzioch D, Martel S.

Med Sci (Paris). 2018 Mar;34(3):197-199. doi: 10.1051/medsci/20183403002. Epub 2018 Mar 16. French. No abstract available.

4.

EphA2 signaling is impacted by carcinoembryonic antigen cell adhesion molecule 1-L expression in colorectal cancer liver metastasis in a cell context-dependent manner.

Arabzadeh A, McGregor K, Breton V, Van Der Kraak L, Akavia UD, Greenwood CMT, Beauchemin N.

Oncotarget. 2017 Nov 1;8(61):104330-104346. doi: 10.18632/oncotarget.22236. eCollection 2017 Nov 28.

5.

CEACAM1 as a multi-purpose target for cancer immunotherapy.

Dankner M, Gray-Owen SD, Huang YH, Blumberg RS, Beauchemin N.

Oncoimmunology. 2017 May 16;6(7):e1328336. doi: 10.1080/2162402X.2017.1328336. eCollection 2017. Review.

6.

Next generation sequencing of progressive colorectal liver metastases after portal vein embolization.

Simoneau E, Chicoine J, Negi S, Salman A, Lazaris A, Hassanain M, Beauchemin N, Petrillo S, Valenti D, Amre R, Metrakos P.

Clin Exp Metastasis. 2017 Jun;34(5):351-361. doi: 10.1007/s10585-017-9855-9. Epub 2017 Jul 31.

PMID:
28758175
7.

Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors.

Lévesque N, Christensen KE, Van Der Kraak L, Best AF, Deng L, Caldwell D, MacFarlane AJ, Beauchemin N, Rozen R.

Mol Carcinog. 2017 Mar;56(3):1030-1040. doi: 10.1002/mc.22568. Epub 2016 Nov 1.

PMID:
27597531
8.

Magneto-aerotactic bacteria deliver drug-containing nanoliposomes to tumour hypoxic regions.

Felfoul O, Mohammadi M, Taherkhani S, de Lanauze D, Zhong Xu Y, Loghin D, Essa S, Jancik S, Houle D, Lafleur M, Gaboury L, Tabrizian M, Kaou N, Atkin M, Vuong T, Batist G, Beauchemin N, Radzioch D, Martel S.

Nat Nanotechnol. 2016 Nov;11(11):941-947. doi: 10.1038/nnano.2016.137. Epub 2016 Aug 15.

9.

The p53 status can influence the role of Sam68 in tumorigenesis.

Li N, Ngo CT, Aleynikova O, Beauchemin N, Richard S.

Oncotarget. 2016 Nov 1;7(44):71651-71659. doi: 10.18632/oncotarget.12305.

10.

CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo.

Wegwitz F, Lenfert E, Gerstel D, von Ehrenstein L, Einhoff J, Schmidt G, Logsdon M, Brandner J, Tiegs G, Beauchemin N, Wagener C, Deppert W, Horst AK.

Oncotarget. 2016 Sep 27;7(39):63730-63746. doi: 10.18632/oncotarget.11650.

11.

Permanent Draft Genome Sequence of Nocardia sp. BMG111209, an Actinobacterium Isolated from Nodules of Casuarina glauca.

Ghodhbane-Gtari F, Beauchemin N, Gueddou A, Hezbri K, Ktari A, Louati M, Nouioui I, Chen A, Huntemann M, Ivanova N, Kyrpides N, Markowitz V, Mavrommatis K, Pagani I, Sen A, Wall L, Woyke T, Gtari M, Tisa LS.

Genome Announc. 2016 Aug 4;4(4). pii: e00770-16. doi: 10.1128/genomeA.00770-16.

12.

Permanent Improved High-Quality Draft Genome Sequence of Nocardia casuarinae Strain BMG51109, an Endophyte of Actinorhizal Root Nodules of Casuarina glauca.

Ghodhbane-Gtari F, Beauchemin N, Louati M, Nouioui I, Ktari A, Hezbri K, Gueddou A, Chen A, Huntemann M, Ivanova N, Kyrpides N, Markowitz V, Mavrommatis K, Pagani I, Sen A, Wall L, Woyke T, Gtari M, Tisa LS.

Genome Announc. 2016 Aug 4;4(4). pii: e00799-16. doi: 10.1128/genomeA.00799-16.

13.

From Solo in the Silo to Strategic Training Programs.

Koritzinsky M, Koch CA, Riley B, Beauchemin N, Johnston G, Johnston M, Koropatnick J, Loiselle CG, Maslowska M, McCormick C, Miller WH Jr, Mulligan L, Tsao MS.

CBE Life Sci Educ. 2016 Spring;15(1):le1. No abstract available.

14.

Mutational Profiles Reveal an Aberrant TGF-β-CEA Regulated Pathway in Colon Adenomas.

Chen J, Raju GS, Jogunoori W, Menon V, Majumdar A, Chen JS, Gi YJ, Jeong YS, Phan L, Belkin M, Gu S, Kundra S, Mistry NA, Zhang J, Su X, Li S, Lin SH, Javle M, McMurray JS, Rahlfs TF, Mishra B, White J, Rashid A, Beauchemin N, Weston BR, Shafi MA, Stroehlein JR, Davila M, Akbani R, Weinstein JN, Wu X, Mishra L.

PLoS One. 2016 Apr 21;11(4):e0153933. doi: 10.1371/journal.pone.0153933. eCollection 2016.

15.

Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.

Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS.

Nature. 2016 Aug 18;536(7616):359. doi: 10.1038/nature17421. Epub 2016 Mar 16. No abstract available.

16.

Mapping hyper-susceptibility to colitis-associated colorectal cancer in FVB/NJ mice.

Van Der Kraak L, Langlais D, Jothy S, Beauchemin N, Gros P.

Mamm Genome. 2016 Jun;27(5-6):213-24. doi: 10.1007/s00335-016-9625-z. Epub 2016 Mar 15.

PMID:
26979842
17.

Colitis-associated colon cancer: Is it in your genes?

Van Der Kraak L, Gros P, Beauchemin N.

World J Gastroenterol. 2015 Nov 7;21(41):11688-99. doi: 10.3748/wjg.v21.i41.11688. Review.

18.

The Nlrp3 Inflammasome Suppresses Colorectal Cancer Metastatic Growth in the Liver by Promoting Natural Killer Cell Tumoricidal Activity.

Dupaul-Chicoine J, Arabzadeh A, Dagenais M, Douglas T, Champagne C, Morizot A, Rodrigue-Gervais IG, Breton V, Colpitts SL, Beauchemin N, Saleh M.

Immunity. 2015 Oct 20;43(4):751-63. doi: 10.1016/j.immuni.2015.08.013. Epub 2015 Sep 15.

19.

Draft Genome Sequence of Frankia sp. Strain DC12, an Atypical, Noninfective, Ineffective Isolate from Datisca cannabina.

Tisa LS, Beauchemin N, Cantor MN, Furnholm T, Ghodhbane-Gtari F, Goodwin L, Copeland A, Gtari M, Huntemann M, Ivanova N, Kyrpides N, Markowitz V, Mavrommatis K, Mikhailova N, Nouioui I, Oshone R, Ovchinnikova G, Pagani I, Palaniappan K, Pati A, Sen A, Shapiro N, Szeto E, Wall L, Wishart J, Woyke T.

Genome Announc. 2015 Aug 6;3(4). pii: e00889-15. doi: 10.1128/genomeA.00889-15.

20.

CEACAM1 regulates integrin αIIbβ3-mediated functions in platelets.

Yip J, Alshahrani M, Beauchemin N, Jackson DE.

Platelets. 2016;27(2):168-77. doi: 10.3109/09537104.2015.1064102. Epub 2015 Jul 21.

PMID:
26196244
21.

CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production.

Khairnar V, Duhan V, Maney SK, Honke N, Shaabani N, Pandyra AA, Seifert M, Pozdeev V, Xu HC, Sharma P, Baldin F, Marquardsen F, Merches K, Lang E, Kirschning C, Westendorf AM, Häussinger D, Lang F, Dittmer U, Küppers R, Recher M, Hardt C, Scheffrahn I, Beauchemin N, Göthert JR, Singer BB, Lang PA, Lang KS.

Nat Commun. 2015 Feb 18;6:6217. doi: 10.1038/ncomms7217.

22.

Carcinoembryonic Antigen Cell Adhesion Molecule 1 long isoform modulates malignancy of poorly differentiated colon cancer cells.

Arabzadeh A, Dupaul-Chicoine J, Breton V, Haftchenary S, Yumeen S, Turbide C, Saleh M, McGregor K, Greenwood CM, Akavia UD, Blumberg RS, Gunning PT, Beauchemin N.

Gut. 2016 May;65(5):821-9. doi: 10.1136/gutjnl-2014-308781. Epub 2015 Feb 9.

23.

Inflammation-induced tumorigenesis in mouse colon is caspase-6 independent.

Foveau B, Van Der Kraak L, Beauchemin N, Albrecht S, LeBlanc AC.

PLoS One. 2014 Dec 3;9(12):e114270. doi: 10.1371/journal.pone.0114270. eCollection 2014.

24.

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.

Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS.

Nature. 2015 Jan 15;517(7534):386-90. doi: 10.1038/nature13848. Epub 2014 Oct 26. Erratum in: Nature. 2016 Aug 18;536(7616):359.

25.

p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition.

Hudson J, Ha JR, Sabourin V, Ahn R, La Selva R, Livingstone J, Podmore L, Knight J, Forrest L, Beauchemin N, Hallett M, Park M, Ursini-Siegel J.

Mol Cell Biol. 2014 Oct 1;34(19):3689-701. doi: 10.1128/MCB.00341-14. Epub 2014 Jul 28.

26.

Contrasted reactivity to oxygen tensions in Frankia sp. strain CcI3 throughout nitrogen fixation and assimilation.

Ghodhbane-Gtari F, Hezbri K, Ktari A, Sbissi I, Beauchemin N, Gtari M, Tisa LS.

Biomed Res Int. 2014;2014:568549. doi: 10.1155/2014/568549. Epub 2014 May 28.

27.

Hepatocyte-specific Ptpn6 deletion promotes hepatic lipid accretion, but reduces NAFLD in diet-induced obesity: potential role of PPARγ.

Xu E, Forest MP, Schwab M, Avramoglu RK, St-Amand E, Caron AZ, Bellmann K, Shum M, Voisin G, Paquet M, Montoudis A, Lévy E, Siminovitch KA, Neel BG, Beauchemin N, Marette A.

Hepatology. 2014 May;59(5):1803-15. doi: 10.1002/hep.26957. Epub 2014 Apr 1.

PMID:
24327268
28.

What stories can the Frankia genomes start to tell us?

Tisa LS, Beauchemin N, Gtari M, Sen A, Wall LG.

J Biosci. 2013 Nov;38(4):719-26.

29.

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis.

Beauchemin N, Arabzadeh A.

Cancer Metastasis Rev. 2013 Dec;32(3-4):643-71. doi: 10.1007/s10555-013-9444-6. Review.

PMID:
23903773
30.

Draft Genome Sequence of Frankia sp. Strain BCU110501, a Nitrogen-Fixing Actinobacterium Isolated from Nodules of Discaria trinevis.

Wall LG, Beauchemin N, Cantor MN, Chaia E, Chen A, Detter JC, Furnholm T, Ghodhbane-Gtari F, Goodwin L, Gtari M, Han C, Han J, Huntemann M, Hua SX, Ivanova N, Kyrpides N, Markowitz V, Mavrommatis K, Mikhailova N, Nordberg HP, Nouioui I, Ovchinnikova G, Pagani I, Pati A, Sen A, Sur S, Szeto E, Thakur S, Wei CL, Woyke T, Tisa LS.

Genome Announc. 2013 Jul 11;1(4). pii: e00503-13. doi: 10.1128/genomeA.00503-13.

31.

Draft Genome Sequence of Frankia sp. Strain BMG5.12, a Nitrogen-Fixing Actinobacterium Isolated from Tunisian Soils.

Nouioui I, Beauchemin N, Cantor MN, Chen A, Detter JC, Furnholm T, Ghodhbane-Gtari F, Goodwin L, Gtari M, Han C, Han J, Huntemann M, Hua SX, Ivanova N, Kyrpides N, Markowitz V, Mavrommatis K, Mikhailova N, Nordberg HP, Ovchinnikova G, Pagani I, Pati A, Sen A, Sur S, Szeto E, Thakur S, Wall L, Wei CL, Woyke T, Tisa LS.

Genome Announc. 2013 Jul 11;1(4). pii: e00468-13. doi: 10.1128/genomeA.00468-13.

32.

Ceacam1 deletion causes vascular alterations in large vessels.

Najjar SM, Ledford KJ, Abdallah SL, Paus A, Russo L, Kaw MK, Ramakrishnan SK, Muturi HT, Raphael CK, Lester SG, Heinrich G, Pierre SV, Benndorf R, Kleff V, Jaffa AA, Lévy E, Vazquez G, Goldberg IJ, Beauchemin N, Scalia R, Ergün S.

Am J Physiol Endocrinol Metab. 2013 Aug 15;305(4):E519-29. doi: 10.1152/ajpendo.00266.2013. Epub 2013 Jun 25.

33.

CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling.

Hosomi S, Chen Z, Baker K, Chen L, Huang YH, Olszak T, Zeissig S, Wang JH, Mandelboim O, Beauchemin N, Lanier LL, Blumberg RS.

Eur J Immunol. 2013 Sep;43(9):2473-83. doi: 10.1002/eji.201242676. Epub 2013 Jun 18.

34.

Positional mapping and candidate gene analysis of the mouse Ccs3 locus that regulates differential susceptibility to carcinogen-induced colorectal cancer.

Meunier C, Van Der Kraak L, Turbide C, Groulx N, Labouba I, Cingolani P, Blanchette M, Yeretssian G, Mes-Masson AM, Saleh M, Beauchemin N, Gros P.

PLoS One. 2013;8(3):e58733. doi: 10.1371/journal.pone.0058733. Epub 2013 Mar 14.

35.

Draft genome sequence of Frankia sp. strain QA3, a nitrogen-fixing actinobacterium isolated from the root nodule of Alnus nitida.

Sen A, Beauchemin N, Bruce D, Chain P, Chen A, Walston Davenport K, Deshpande S, Detter C, Furnholm T, Ghodbhane-Gtari F, Goodwin L, Gtari M, Han C, Han J, Huntemann M, Ivanova N, Kyrpides N, Land ML, Markowitz V, Mavrommatis K, Nolan M, Nouioui I, Pagani I, Pati A, Pitluck S, Santos CL, Sur S, Szeto E, Tavares F, Teshima H, Thakur S, Wall L, Woyke T, Wishart J, Tisa LS.

Genome Announc. 2013 Mar 21;1(2):e0010313. doi: 10.1128/genomeA.00103-13.

36.

Draft genome sequence of Frankia sp. strain CN3, an atypical, noninfective (Nod-) ineffective (Fix-) isolate from Coriaria nepalensis.

Ghodhbane-Gtari F, Beauchemin N, Bruce D, Chain P, Chen A, Walston Davenport K, Deshpande S, Detter C, Furnholm T, Goodwin L, Gtari M, Han C, Han J, Huntemann M, Ivanova N, Kyrpides N, Land ML, Markowitz V, Mavrommatis K, Nolan M, Nouioui I, Pagani I, Pati A, Pitluck S, Santos CL, Sen A, Sur S, Szeto E, Tavares F, Teshima H, Thakur S, Wall L, Woyke T, Tisa LS.

Genome Announc. 2013 Mar 14;1(2):e0008513. doi: 10.1128/genomeA.00085-13.

37.

Stromal CEACAM1 expression regulates colorectal cancer metastasis.

Arabzadeh A, Beauchemin N.

Oncoimmunology. 2012 Oct 1;1(7):1205-1207.

38.

The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction.

Chen L, Chen Z, Baker K, Halvorsen EM, da Cunha AP, Flak MB, Gerber G, Huang YH, Hosomi S, Arthur JC, Dery KJ, Nagaishi T, Beauchemin N, Holmes KV, Ho JW, Shively JE, Jobin C, Onderdonk AB, Bry L, Weiner HL, Higgins DE, Blumberg RS.

Immunity. 2012 Nov 16;37(5):930-46. doi: 10.1016/j.immuni.2012.07.016. Epub 2012 Nov 1.

39.

Hepatocyte-specific Ptpn6 deletion protects from obesity-linked hepatic insulin resistance.

Xu E, Charbonneau A, Rolland Y, Bellmann K, Pao L, Siminovitch KA, Neel BG, Beauchemin N, Marette A.

Diabetes. 2012 Aug;61(8):1949-58. doi: 10.2337/db11-1502. Epub 2012 Jun 14.

40.

Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer.

Arabzadeh A, Chan C, Nouvion AL, Breton V, Benlolo S, DeMarte L, Turbide C, Brodt P, Ferri L, Beauchemin N.

Oncogene. 2013 Feb 14;32(7):849-60. doi: 10.1038/onc.2012.112. Epub 2012 Apr 2.

PMID:
22469976
41.

CEACAM1 dampens antitumor immunity by down-regulating NKG2D ligand expression on tumor cells.

Chen Z, Chen L, Baker K, Olszak T, Zeissig S, Huang YH, Kuo TT, Mandelboim O, Beauchemin N, Lanier LL, Blumberg RS.

J Exp Med. 2011 Dec 19;208(13):2633-40. doi: 10.1084/jem.20102575. Epub 2011 Dec 5.

42.

Casuarina root exudates alter the physiology, surface properties, and plant infectivity of Frankia sp. strain CcI3.

Beauchemin NJ, Furnholm T, Lavenus J, Svistoonoff S, Doumas P, Bogusz D, Laplaze L, Tisa LS.

Appl Environ Microbiol. 2012 Jan;78(2):575-80. doi: 10.1128/AEM.06183-11. Epub 2011 Nov 18.

43.

CEACAM1 deficiency delays important wound healing processes.

LeBlanc S, Arabzadeh A, Benlolo S, Breton V, Turbide C, Beauchemin N, Nouvion AL.

Wound Repair Regen. 2011 Nov;19(6):745-52. doi: 10.1111/j.1524-475X.2011.00742.x.

PMID:
22092845
44.

Development of a semi-high-throughput growth assay for the filamentous actinobacteria Frankia.

Furnholm T, Beauchemin N, Tisa LS.

Arch Microbiol. 2012 Jan;194(1):13-20. doi: 10.1007/s00203-011-0748-z. Epub 2011 Aug 23.

PMID:
21861152
45.

Phylogenetic perspectives of nitrogen-fixing actinobacteria.

Gtari M, Ghodhbane-Gtari F, Nouioui I, Beauchemin N, Tisa LS.

Arch Microbiol. 2012 Jan;194(1):3-11. doi: 10.1007/s00203-011-0733-6. Epub 2011 Jul 21. Review.

PMID:
21779790
46.

Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation.

Lu SX, Kappel LW, Charbonneau-Allard AM, Atallah R, Holland AM, Turbide C, Hubbard VM, Rotolo JA, Smith M, Suh D, King C, Rao UK, Yim N, Bautista JL, Jenq RR, Penack O, Na IK, Liu C, Murphy G, Alpdogan O, Blumberg RS, Macian F, Holmes KV, Beauchemin N, van den Brink MR.

PLoS One. 2011;6(7):e21611. doi: 10.1371/journal.pone.0021611. Epub 2011 Jul 6.

47.

The colorectal tumor microenvironment: the next decade.

Beauchemin N.

Cancer Microenviron. 2011 Aug;4(2):181-5. doi: 10.1007/s12307-011-0074-7. Epub 2011 Jul 7.

48.

Phylogeny of members of the Frankia genus based on gyrB, nifH and glnII sequences.

Nouioui I, Ghodhbane-Gtari F, Beauchemin NJ, Tisa LS, Gtari M.

Antonie Van Leeuwenhoek. 2011 Nov;100(4):579-87. doi: 10.1007/s10482-011-9613-y. Epub 2011 Jun 29.

PMID:
21713368
49.

Genetic control of susceptibility to carcinogen-induced colorectal cancer in mice: the Ccs3 and Ccs5 loci regulate different aspects of tumorigenesis.

Meunier C, Kwan T, Turbide C, Beauchemin N, Gros P.

Cell Cycle. 2011 Jun 1;10(11):1739-49. Epub 2011 Jun 1.

PMID:
21543896
50.

CEACAM1 creates a pro-angiogenic tumor microenvironment that supports tumor vessel maturation.

Gerstel D, Wegwitz F, Jannasch K, Ludewig P, Scheike K, Alves F, Beauchemin N, Deppert W, Wagener C, Horst AK.

Oncogene. 2011 Oct 13;30(41):4275-88. doi: 10.1038/onc.2011.146. Epub 2011 May 2.

PMID:
21532628

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