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Items: 11


Circulating Myeloid Derived Suppressor Cells (MDSC) That Accumulate in Premalignancy Share Phenotypic and Functional Characteristics With MDSC in Cancer.

Ma P, Beatty PL, McKolanis J, Brand R, Schoen RE, Finn OJ.

Front Immunol. 2019 Jun 19;10:1401. doi: 10.3389/fimmu.2019.01401. eCollection 2019.


Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines, mediated by NF-κB p65 and EzH2, in colitis-associated cancer.

Cascio S, Faylo JL, Sciurba JC, Xue J, Ranganathan S, Lohmueller JJ, Beatty PL, Finn OJ.

Oncotarget. 2017 Oct 27;8(62):105284-105298. doi: 10.18632/oncotarget.22168. eCollection 2017 Dec 1.


Immunobiology and immunosurveillance in patients with intraductal papillary mucinous neoplasms (IPMNs), premalignant precursors of pancreatic adenocarcinomas.

Beatty PL, van der Geest R, Hashash JG, Kimura T, Gutkin D, Brand RE, Finn OJ.

Cancer Immunol Immunother. 2016 Jul;65(7):771-8. doi: 10.1007/s00262-016-1838-1. Epub 2016 Apr 22.


Cancer immunoprevention.

Finn OJ, Beatty PL.

Curr Opin Immunol. 2016 Apr;39:52-8. doi: 10.1016/j.coi.2016.01.002. Epub 2016 Jan 19. Review.


Influenza virus infection elicits protective antibodies and T cells specific for host cell antigens also expressed as tumor-associated antigens: a new view of cancer immunosurveillance.

Iheagwara UK, Beatty PL, Van PT, Ross TM, Minden JS, Finn OJ.

Cancer Immunol Res. 2014 Mar;2(3):263-73. doi: 10.1158/2326-6066.CIR-13-0125. Epub 2013 Dec 5.


Preventing cancer by targeting abnormally expressed self-antigens: MUC1 vaccines for prevention of epithelial adenocarcinomas.

Beatty PL, Finn OJ.

Ann N Y Acad Sci. 2013 May;1284:52-6. doi: 10.1111/nyas.12108.


Importance of MUC1 and spontaneous mouse tumor models for understanding the immunobiology of human adenocarcinomas.

Finn OJ, Gantt KR, Lepisto AJ, Pejawar-Gaddy S, Xue J, Beatty PL.

Immunol Res. 2011 Aug;50(2-3):261-8. doi: 10.1007/s12026-011-8214-1. Review.


Tumor immunology: basic and clinical advances.

Beatty PL, Cascio S, Lutz E.

Cancer Res. 2011 Jul 1;71(13):4338-43. doi: 10.1158/0008-5472.CAN-11-0717. Epub 2011 Jun 28.


Vaccine against MUC1 antigen expressed in inflammatory bowel disease and cancer lessens colonic inflammation and prevents progression to colitis-associated colon cancer.

Beatty PL, Narayanan S, Gariépy J, Ranganathan S, Finn OJ.

Cancer Prev Res (Phila). 2010 Apr;3(4):438-46. doi: 10.1158/1940-6207.CAPR-09-0194. Epub 2010 Mar 23.


Inflammation driven by overexpression of the hypoglycosylated abnormal mucin 1 (MUC1) links inflammatory bowel disease and pancreatitis.

Kadayakkara DK, Beatty PL, Turner MS, Janjic JM, Ahrens ET, Finn OJ.

Pancreas. 2010 May;39(4):510-5. doi: 10.1097/MPA.0b013e3181bd6501.


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