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Four Ways to Fit an Ion Channel Model.

Clerx M, Beattie KA, Gavaghan DJ, Mirams GR.

Biophys J. 2019 Aug 6. pii: S0006-3495(19)30666-6. doi: 10.1016/j.bpj.2019.08.001. [Epub ahead of print]


Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence.

Lei CL, Clerx M, Beattie KA, Melgari D, Hancox JC, Gavaghan DJ, Polonchuk L, Wang K, Mirams GR.

Biophys J. 2019 Jul 25. pii: S0006-3495(19)30598-3. doi: 10.1016/j.bpj.2019.07.030. [Epub ahead of print]


Determining known-group validity and test-retest reliability in the PEQ (personalized exercise questionnaire).

Rodrigues IB, Adachi JD, Beattie KA, Lau A, MacDermid JC.

BMC Musculoskelet Disord. 2019 Aug 14;20(1):373. doi: 10.1186/s12891-019-2761-3.


Preclinical efficacy of hK2 targeted [177Lu]hu11B6 for prostate cancer theranostics.

Timmermand OV, Elgqvist J, Beattie KA, Örbom A, Larsson E, Eriksson SE, Thorek DLJ, Beattie BJ, Tran TA, Ulmert D, Strand SE.

Theranostics. 2019 Apr 6;9(8):2129-2142. doi: 10.7150/thno.31179. eCollection 2019.


Assessing the Educational Needs of Canadians with Systemic Sclerosis.

Semalulu T, Beattie KA, Larché MJ.

J Rheumatol. 2019 Jun;46(6):658-659. doi: 10.3899/jrheum.180554. Epub 2019 Apr 1. No abstract available.


Factors that influence Canadian internal medicine residents' choice to pursue a rheumatology career.

Matsos M, Docherty-Skippen SM, Yelovich MC, Beattie KA.

Clin Rheumatol. 2019 Jan;38(1):229-234. doi: 10.1007/s10067-018-4222-z. Epub 2018 Jul 20.


Treatment of small intestinal bacterial overgrowth in systemic sclerosis: a systematic review.

Pittman N, Rawn SM, Wang M, Masetto A, Beattie KA, Larché M.

Rheumatology (Oxford). 2018 Oct 1;57(10):1802-1811. doi: 10.1093/rheumatology/key175. Review.


Ophthalmoplegia in an elderly woman with giant cell arteritis.

Quinn R, Hawkes C, Lodhi A, Tang S, Beattie KA, van Adel B, Larché MJ.

Rheumatol Adv Pract. 2018 Jun 29;2(2):rky020. doi: 10.1093/rap/rky020. eCollection 2018. No abstract available.


Reproducible model development in the cardiac electrophysiology Web Lab.

Daly AC, Clerx M, Beattie KA, Cooper J, Gavaghan DJ, Mirams GR.

Prog Biophys Mol Biol. 2018 Nov;139:3-14. doi: 10.1016/j.pbiomolbio.2018.05.011. Epub 2018 May 26.


Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics.

Beattie KA, Hill AP, Bardenet R, Cui Y, Vandenberg JI, Gavaghan DJ, de Boer TP, Mirams GR.

J Physiol. 2018 May 15;596(10):1813-1828. doi: 10.1113/JP275733. Epub 2018 Apr 17.


Development and validation of a new tool to measure the facilitators, barriers and preferences to exercise in people with osteoporosis.

Rodrigues IB, Adachi JD, Beattie KA, MacDermid JC.

BMC Musculoskelet Disord. 2017 Dec 19;18(1):540. doi: 10.1186/s12891-017-1914-5.


Corrigendum: Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment.

Dutta S, Chang KC, Beattie KA, Sheng J, Tran PN, Wu WW, Wu M, Strauss DG, Colatsky T, Li Z.

Front Physiol. 2017 Dec 6;8:1025. doi: 10.3389/fphys.2017.01025. eCollection 2017.


Uncertainty Quantification Reveals the Importance of Data Variability and Experimental Design Considerations for in Silico Proarrhythmia Risk Assessment.

Chang KC, Dutta S, Mirams GR, Beattie KA, Sheng J, Tran PN, Wu M, Wu WW, Colatsky T, Strauss DG, Li Z.

Front Physiol. 2017 Nov 21;8:917. doi: 10.3389/fphys.2017.00917. eCollection 2017.


Optimization of an In silico Cardiac Cell Model for Proarrhythmia Risk Assessment.

Dutta S, Chang KC, Beattie KA, Sheng J, Tran PN, Wu WW, Wu M, Strauss DG, Colatsky T, Li Z.

Front Physiol. 2017 Aug 23;8:616. doi: 10.3389/fphys.2017.00616. eCollection 2017. Erratum in: Front Physiol. 2017 Dec 06;8:1025.


Baseline knee adduction moment interacts with body mass index to predict loss of medial tibial cartilage volume over 2.5 years in knee Osteoarthritis.

Brisson NM, Wiebenga EG, Stratford PW, Beattie KA, Totterman S, Tamez-Peña JG, Callaghan JP, Adachi JD, Maly MR.

J Orthop Res. 2017 Nov;35(11):2476-2483. doi: 10.1002/jor.23564. Epub 2017 Apr 7.


Lean muscle volume of the thigh has a stronger relationship with muscle power than muscle strength in women with knee osteoarthritis.

Davison MJ, Maly MR, Keir PJ, Hapuhennedige SM, Kron AT, Adachi JD, Beattie KA.

Clin Biomech (Bristol, Avon). 2017 Jan;41:92-97. doi: 10.1016/j.clinbiomech.2016.11.005. Epub 2016 Nov 25.


Relationships between fatty infiltration in the thigh and calf in women with knee osteoarthritis.

Davison MJ, Maly MR, Adachi JD, Noseworthy MD, Beattie KA.

Aging Clin Exp Res. 2017 Apr;29(2):291-299. doi: 10.1007/s40520-016-0556-z. Epub 2016 Mar 10.


The reliability of a segmentation methodology for assessing intramuscular adipose tissue and other soft-tissue compartments of lower leg MRI images.

Karampatos S, Papaioannou A, Beattie KA, Maly MR, Chan A, Adachi JD, Pritchard JM.

MAGMA. 2016 Apr;29(2):237-44. doi: 10.1007/s10334-015-0510-7. Epub 2015 Dec 24.


Identifying real and perceived barriers to therapeutic education programs for individuals with inflammatory arthritis.

Bain L, Sangrar R, Bornstein C, Lukmanji S, Hapuhennedige S, Thorne C, Beattie KA.

Clin Rheumatol. 2016 Sep;35(9):2317-26. doi: 10.1007/s10067-015-3097-5. Epub 2015 Oct 29.


Assessing the Reliability of a Semiautomated Segmentation Algorithm for Quantifying Erosions in the Metacarpophalangeal Joints of Patients with Rheumatoid Arthritis.

Tomizza MA, Jessome MA, Barbosa J, Beattie KA, Bensen WG, Bobba RS, Cividino AA, Emond PD, Gordon C, Hart L, Ioannidis G, Koh MX, Larché M, Tavares R, Tytus S, Adachi JD.

J Rheumatol. 2015 Sep;42(9):1582-6. doi: 10.3899/jrheum.141139. Epub 2015 Jul 15.


Do Knee Moments Normalized to Measures of Knee Cartilage Area Better Classify the Severity of Knee Osteoarthritis?

Brisson NM, Stratford PW, Totterman S, Tamez-Peña JG, Beattie KA, Adachi JD, Maly MR.

J Appl Biomech. 2015 Dec;31(6):415-22. doi: 10.1123/jab.2014-0249. Epub 2015 Jul 9.


Knee adduction moment relates to medial femoral and tibial cartilage morphology in clinical knee osteoarthritis.

Maly MR, Acker SM, Totterman S, Tamez-Peña J, Stratford PW, Callaghan JP, Adachi JD, Beattie KA.

J Biomech. 2015 Sep 18;48(12):3495-501. doi: 10.1016/j.jbiomech.2015.04.039. Epub 2015 May 6.


Bone lead (Pb) content at the tibia is associated with thinner distal tibia cortices and lower volumetric bone density in postmenopausal women.

Wong AK, Beattie KA, Bhargava A, Cheung M, Webber CE, Chettle DR, Papaioannou A, Adachi JD; Canadian Multicentre Osteoporosis Study (CaMos) Research Group.

Bone. 2015 Oct;79:58-64. doi: 10.1016/j.bone.2015.05.010. Epub 2015 May 15.


The Relationship between Intramuscular Adipose Tissue, Functional Mobility, and Strength in Postmenopausal Women with and without Type 2 Diabetes.

Pritchard JM, Karampatos S, Beattie KA, Giangregorio LM, Ioannidis G, Atkinson SA, Thabane L, Gerstein H, Punthakee Z, Adachi JD, Papaioannou A.

J Aging Res. 2015;2015:872726. doi: 10.1155/2015/872726. Epub 2015 Jan 27.


Peripheral quantitative computed tomography-derived muscle density and peripheral magnetic resonance imaging-derived muscle adiposity: precision and associations with fragility fractures in women.

Wong AK, Beattie KA, Min KK, Gordon C, Pickard L, Papaioannou A, Adachi JD; Canadian Multicentre Osteoporosis Study (CaMos) Research Group.

J Musculoskelet Neuronal Interact. 2014 Dec;14(4):401-10.


Intermittent and constant pain and physical function or performance in men and women with knee osteoarthritis: data from the osteoarthritis initiative.

Davison MJ, Ioannidis G, Maly MR, Adachi JD, Beattie KA.

Clin Rheumatol. 2016 Feb;35(2):371-9. doi: 10.1007/s10067-014-2810-0. Epub 2014 Nov 8.


A Trimodality Comparison of Volumetric Bone Imaging Technologies. Part III: SD, SEE, LSC Association With Fragility Fractures.

Wong AK, Beattie KA, Min KK, Merali Z, Webber CE, Gordon CL, Papaioannou A, Cheung AM, Adachi JD.

J Clin Densitom. 2015 Jul-Sep;18(3):408-18. doi: 10.1016/j.jocd.2014.07.003. Epub 2014 Aug 13.


A Trimodality Comparison of Volumetric Bone Imaging Technologies. Part II: 1-Yr Change, Long-Term Precision, and Least Significant Change.

Wong AK, Beattie KA, Min KK, Merali Z, Webber CE, Gordon CL, Papaioannou A, Cheung AM, Adachi JD.

J Clin Densitom. 2015 Apr-Jun;18(2):260-9. doi: 10.1016/j.jocd.2014.07.004. Epub 2014 Aug 13.


A trimodality comparison of volumetric bone imaging technologies. Part I: Short-term precision and validity.

Wong AK, Beattie KA, Min KK, Webber CE, Gordon CL, Papaioannou A, Cheung AM, Adachi JD.

J Clin Densitom. 2015 Jan-Mar;18(1):124-35. doi: 10.1016/j.jocd.2014.07.005. Epub 2014 Aug 13.


Improving reliability of pQCT-derived muscle area and density measures using a watershed algorithm for muscle and fat segmentation.

Wong AK, Hummel K, Moore C, Beattie KA, Shaker S, Craven BC, Adachi JD, Papaioannou A, Giangregorio L.

J Clin Densitom. 2015 Jan-Mar;18(1):93-101. doi: 10.1016/j.jocd.2014.04.124. Epub 2014 Jul 1.


Knee power is an important parameter in understanding medial knee joint load in knee osteoarthritis.

Calder KM, Acker SM, Arora N, Beattie KA, Callaghan JP, Adachi JD, Maly MR.

Arthritis Care Res (Hoboken). 2014 May;66(5):687-94. doi: 10.1002/acr.22223.


Appropriate osteoporosis treatment by family physicians in response to FRAX vs CAROC reporting: results from a randomized controlled trial.

Beattie KA, Ioannidis G, MacDermid JC, Grewal R, Papaioannou A, Adachi JD, Hodsman AB.

J Clin Densitom. 2014 Oct-Dec;17(4):458-65. doi: 10.1016/j.jocd.2013.09.007. Epub 2013 Oct 25.


Evaluation of an in silico cardiac safety assay: using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge.

Beattie KA, Luscombe C, Williams G, Munoz-Muriedas J, Gavaghan DJ, Cui Y, Mirams GR.

J Pharmacol Toxicol Methods. 2013 Jul-Aug;68(1):88-96. doi: 10.1016/j.vascn.2013.04.004. Epub 2013 Apr 25.


Changes in trabecular bone microarchitecture in postmenopausal women with and without type 2 diabetes: a two year longitudinal study.

Pritchard JM, Giangregorio LM, Atkinson SA, Beattie KA, Inglis D, Ioannidis G, Gerstein H, Punthakee Z, Adachi JD, Papaioannou A.

BMC Musculoskelet Disord. 2013 Mar 27;14:114. doi: 10.1186/1471-2474-14-114.


Bone mineralization is elevated and less heterogeneous in adults with type 2 diabetes and osteoarthritis compared to controls with osteoarthritis alone.

Pritchard JM, Papaioannou A, Tomowich C, Giangregorio LM, Atkinson SA, Beattie KA, Adachi JD, DeBeer J, Winemaker M, Avram V, Schwarcz HP.

Bone. 2013 May;54(1):76-82. doi: 10.1016/j.bone.2013.01.032. Epub 2013 Jan 26.


A critical review of brand and generic alendronate for the treatment of osteoporosis.

Brown JP, Davison KS, Olszynski WP, Beattie KA, Adachi JD.

Springerplus. 2013 Oct 21;2:550. doi: 10.1186/2193-1801-2-550. eCollection 2013. Review.


Relationship of intermuscular fat volume in the thigh with knee extensor strength and physical performance in women at risk of or with knee osteoarthritis.

Maly MR, Calder KM, Macintyre NJ, Beattie KA.

Arthritis Care Res (Hoboken). 2013 Jan;65(1):44-52. doi: 10.1002/acr.21868.


Accumulation of bone strontium measured by in vivo XRF in rats supplemented with strontium citrate and strontium ranelate.

Wohl GR, Chettle DR, Pejović-Milić A, Druchok C, Webber CE, Adachi JD, Beattie KA.

Bone. 2013 Jan;52(1):63-9. doi: 10.1016/j.bone.2012.09.002. Epub 2012 Sep 17.


Association of larger holes in the trabecular bone at the distal radius in postmenopausal women with type 2 diabetes mellitus compared to controls.

Pritchard JM, Giangregorio LM, Atkinson SA, Beattie KA, Inglis D, Ioannidis G, Punthakee Z, Adachi JD, Papaioannou A.

Arthritis Care Res (Hoboken). 2012 Jan;64(1):83-91. doi: 10.1002/acr.20602. Erratum in: Arthritis Care Res (Hoboken). 2012 Jun;64(6):944.


Effect of low-intensity pulsed ultrasound on the cartilage repair in people with mild to moderate knee osteoarthritis: a double-blinded, randomized, placebo-controlled pilot study.

Loyola-Sánchez A, Richardson J, Beattie KA, Otero-Fuentes C, Adachi JD, MacIntyre NJ.

Arch Phys Med Rehabil. 2012 Jan;93(1):35-42. doi: 10.1016/j.apmr.2011.07.196.


Atypical femoral fractures in patients taking longterm alendronate.

Mulgund M, Beattie KA, Anaspure R, Matsos M, Patel A, Adachi JD.

J Rheumatol. 2011 Dec;38(12):2686-7. doi: 10.3899/jrheum.110725. No abstract available.


Longitudinal changes in intermuscular fat volume and quadriceps muscle volume in the thighs of women with knee osteoarthritis.

Beattie KA, MacIntyre NJ, Ramadan K, Inglis D, Maly MR.

Arthritis Care Res (Hoboken). 2012 Jan;64(1):22-9. doi: 10.1002/acr.20628.


The sensitivity, specificity and reliability of the GALS (gait, arms, legs and spine) examination when used by physiotherapists and physiotherapy students to detect rheumatoid arthritis.

Beattie KA, Macintyre NJ, Pierobon J, Coombs J, Horobetz D, Petric A, Pimm M, Kean W, Larché MJ, Cividino A.

Physiotherapy. 2011 Sep;97(3):196-202. doi: 10.1016/ Epub 2011 Feb 2.


Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals.

McMahon M, Lamont DJ, Beattie KA, Hayes JD.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18838-43. doi: 10.1073/pnas.1007387107. Epub 2010 Oct 18.


Multiplanar reconstruction recovers morphological cartilage assessment reproducibility from maloriented coronal MRI scans.

Inglis D, Wong AK, Eckstein F, Adachi JD, Beattie KA.

Magn Reson Med. 2011 Mar;65(3):790-5. doi: 10.1002/mrm.22659. Epub 2010 Oct 11.


Cell homeostasis in a Leishmania major mutant overexpressing the spliced leader RNA is maintained by an increased proteolytic activity.

Toledo JS, Ferreira TR, Defina TP, Dossin Fde M, Beattie KA, Lamont DJ, Cloutier S, Papadopoulou B, Schenkman S, Cruz AK.

Int J Biochem Cell Biol. 2010 Oct;42(10):1661-71. doi: 10.1016/j.biocel.2010.06.013. Epub 2010 Jun 22.


Quantitative analysis of subchondral sclerosis of the tibia by bone texture parameters in knee radiographs: site-specific relationships with joint space width.

Wong AK, Beattie KA, Emond PD, Inglis D, Duryea J, Doan A, Ioannidis G, Webber CE, O'Neill J, de Beer J, Adachi JD, Papaioannou A.

Osteoarthritis Cartilage. 2009 Nov;17(11):1453-60. doi: 10.1016/j.joca.2009.05.004. Epub 2009 May 18.


Assessing adherence to teriparatide therapy, causes of nonadherence and effect of adherence on bone mineral density measurements in osteoporotic patients at high risk for fracture.

Mulgund M, Beattie KA, Wong AK, Papaioannou A, Adachi JD.

Ther Adv Musculoskelet Dis. 2009 Feb;1(1):5-11. doi: 10.1177/1759720X09339551.

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