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Items: 28

1.

Assessment of acute toxicity and cytotoxicity of fluorescent markers produced by cardanol and glycerol, which are industrial waste, to different biological models.

Pelizaro BI, Braga FC, Crispim BDA, de Barros LGML, Pessatto LR, Oliveira EJT, Vani JM, de Souza AP, Grisolia AB, Antoniolli-Silva ACMB, de Lima DP, Dos Santos Jaques JA, Beatriz A, Oliveira RJ.

Environ Sci Pollut Res Int. 2019 Mar;26(9):9193-9202. doi: 10.1007/s11356-019-04376-y. Epub 2019 Feb 4.

PMID:
30719661
2.

Carbonyl Compounds' Journey to Amide Bond Formation.

Narendar Reddy T, Beatriz A, Jayathirtha Rao V, de Lima DP.

Chem Asian J. 2019 Feb 1;14(3):344-388. doi: 10.1002/asia.201801560. Epub 2019 Jan 9. Review.

PMID:
30623602
3.

Resorcinolic lipid 3-heptyl-3,4,6-trimethoxy-3H-isobenzofuran-1-one is a strategy for melanoma treatment.

Navarro SD, Pessatto LR, Meza A, de Oliveira EJT, Auharek SA, Vilela LC, de Lima DP, de Azevedo RB, Kassuya CAL, Cáceres OIA, da Silva Gomes R, Beatriz A, Oliveira RJ, Martines MAU.

Life Sci. 2018 Sep 15;209:300-312. doi: 10.1016/j.lfs.2018.08.022. Epub 2018 Aug 10.

PMID:
30102904
4.

Evaluation of the Antitumor Potential of the Resorcinolic Lipid 3-Heptyl-3,4,6-trimethoxy-3H-isobenzofuran-1-one in Breast Cancer Cells.

Rabacow APM, Meza A, DE Oliveira EJT, DE David N, Vitor N, Antoniolli-Silva ACMB, DE Fátima Cepa Matos M, Perdomo RT, DA Silva Gomes R, DE Lima DP, Beatriz A, Oliveira RJ.

Anticancer Res. 2018 Aug;38(8):4565-4576. doi: 10.21873/anticanres.12761.

PMID:
30061223
5.

The mixture of cashew nut shell liquid and castor oil results in an efficient larvicide against Aedes aegypti that does not alter embryo-fetal development, reproductive performance or DNA integrity.

Vani JM, Monreal MTFD, Auharek SA, Cunha-Laura AL, de Arruda EJ, Lima AR, da Silva CM, Antoniolli-Silva ACMB, de Lima DP, Beatriz A, Oliveira RJ.

PLoS One. 2018 Mar 19;13(3):e0193509. doi: 10.1371/journal.pone.0193509. eCollection 2018.

6.

Assessment of genetic integrity, splenic phagocytosis and cell death potential of (Z)-4-((1,5-dimethyl-3-oxo-2-phenyl-2,3dihydro-1H-pyrazol-4-yl) amino)-4-oxobut-2-enoic acid and its effect when combined with commercial chemotherapeutics.

Oliveira RJ, da Cruz Leite Santos N, Pesarini JR, de Oliveira BC, Berno CR, de Araújo FHS, da Silveira IOMF, Nascimento RO, Brochado Antoniolli-Silva ACM, Duenhas Monreal AC, Beatriz A, de Lima DP, da Silva Gomes R.

Genet Mol Biol. 2018 Jan-Mar;41(1):154-166. doi: 10.1590/1678-4685-GMB-2017-0091. Epub 2018 Feb 19.

7.

In vivo chemotherapeutic insight of a novel isocoumarin (3-hexyl-5,7-dimethoxy-isochromen-1-one): Genotoxicity, cell death induction, leukometry and phagocytic evaluation.

Araújo FHS, Figueiredo DR, Auharek SA, Pesarini JR, Meza A, Gomes RS, Monreal ACD, Antoniolli-Silva ACMB, Lima DP, Kassuya CAL, Beatriz A, Oliveira RJ.

Genet Mol Biol. 2017 Jul-Sep 01;40(3):665-675. doi: 10.1590/1678-4685-GMB-2016-0316.

8.

A potent larvicidal agent against Aedes aegypti mosquito from cardanol.

Paiva DR, Lima DP, Avvari NP, Arruda EJ, Cabrini I, Marques MR, Santos EAD, Biaggio FC, Sangi DP, Beatriz A.

An Acad Bras Cienc. 2017 May;89(1 Suppl 0):373-382. doi: 10.1590/0001-3765201720160615.

9.

4-Aminoantipyrine reduces toxic and genotoxic effects of doxorubicin, cisplatin, and cyclophosphamide in male mice.

Berno CR, Rós Bde T, da Silveira IO, Coelho HR, Antoniolli AC, Beatriz A, de Lima DP, Monreal AC, Sousa FG, da Silva Gomes R, Oliveira RJ.

Mutat Res Genet Toxicol Environ Mutagen. 2016 Jul;805:19-24. doi: 10.1016/j.mrgentox.2016.05.009. Epub 2016 May 20.

10.

Cardanol: toxicogenetic assessment and its effects when combined with cyclophosphamide.

Schneider BU, Meza A, Beatriz A, Pesarini JR, Carvalho PC, Mauro Mde O, Karaziack CB, Cunha-Laura AL, Monreal AC, Matuo R, Lima DP, Oliveira RJ.

Genet Mol Biol. 2016 Apr-Jun;39(2):279-89. doi: 10.1590/1678-4685-GMB-2015-0170.

11.

A novel cytosporone 3-Heptyl-4,6-dihydroxy-3H-isobenzofuran-1-one: synthesis; toxicological, apoptotic and immunomodulatory properties; and potentiation of mutagenic damage.

Oliveira RJ, Navarro SD, de Lima DP, Meza A, Pesarini JR, da Silva Gomes R, Karaziack CB, de Oliveira Mauro M, Cunha-Laura AL, Monreal AC, Romão W, Júnior VL, Beatriz A.

BMC Cancer. 2015 Jul 31;15:561. doi: 10.1186/s12885-015-1532-2.

12.

Novel naphthoquinone derivatives and evaluation of their trypanocidal and leishmanicidal activities.

Naujorks AA, da Silva AO, Lopes Rda S, de Albuquerque S, Beatriz A, Marques MR, de Lima DP.

Org Biomol Chem. 2015 Jan 14;13(2):428-37. doi: 10.1039/c4ob01869a. Epub 2014 Nov 5.

PMID:
25370790
13.

A new synthetic resorcinolic lipid 3-heptyl-3,4,6-trimethoxy-3H-isobenzofuran-1-one: evaluation of toxicology and ability to potentiate the mutagenic and apoptotic effects of cyclophosphamide.

Navarro SD, Beatriz A, Meza A, Pesarini JR, Gomes Rda S, Karaziack CB, Cunha-Laura AL, Monreal AC, Romão W, Lacerda Júnior V, Mauro Mde O, Oliveira RJ.

Eur J Med Chem. 2014 Mar 21;75:132-42. doi: 10.1016/j.ejmech.2014.01.057. Epub 2014 Jan 30.

PMID:
24531226
14.

(4-Methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone inhibits tubulin polymerization, induces G2/M arrest, and triggers apoptosis in human leukemia HL-60 cells.

Magalhães HI, Wilke DV, Bezerra DP, Cavalcanti BC, Rotta R, de Lima DP, Beatriz A, Moraes MO, Diniz-Filho J, Pessoa C.

Toxicol Appl Pharmacol. 2013 Oct 1;272(1):117-26. doi: 10.1016/j.taap.2013.06.001. Epub 2013 Jun 10.

PMID:
23756174
15.

Synthesis and biological activity against Trypanosoma cruzi of substituted 1,4-naphthoquinones.

Olímpio da Silva A, da Silva Lopes R, Vieira de Lima R, Santos Suniga Tozatti C, Marques MR, de Albuquerque S, Beatriz A, Pires de Lima D.

Eur J Med Chem. 2013 Feb;60:51-6. doi: 10.1016/j.ejmech.2012.11.034. Epub 2012 Dec 1.

PMID:
23279867
16.

Increment of antimycobaterial activity on lichexanthone derivatives.

Micheletti AC, Honda NK, Pavan FR, Leite CQ, Matos Mde F, Perdomo RT, Bogo D, Alcantara GB, Beatriz A.

Med Chem. 2013 Nov;9(7):904-10.

PMID:
23106287
17.

Assessment of genotoxic effects of (4-methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone in human lymphocytes.

Magalhães HI, Cavalcanti BC, Bezerra DP, Wilke DV, Paiva JC, Rotta R, de Lima DP, Beatriz A, Burbano RR, Costa-Lotufo LV, Moraes MO, Pessoa C.

Toxicol In Vitro. 2011 Dec;25(8):2048-53. doi: 10.1016/j.tiv.2011.08.007. Epub 2011 Aug 22.

18.

In vitro and in vivo antitumor effects of (4-methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone.

Magalhães HI, Bezerra DP, Cavalcanti BC, Wilke DV, Rotta R, de Lima DP, Beatriz A, Alves AP, Bitencourt Fda S, de Figueiredo IS, Alencar NM, Costa-Lotufo LV, Moraes MO, Pessoa C.

Cancer Chemother Pharmacol. 2011 Jul;68(1):45-52. doi: 10.1007/s00280-010-1446-2. Epub 2010 Sep 7.

PMID:
20821328
19.

1H and 13C NMR spectral data of bioactive cage-like polycyclic compounds.

Salles RC, Lacerda V Jr, Beatriz A, Ito FM, dos Santos RB, Greco SJ, de Castro EV, de Lima DP.

Magn Reson Chem. 2010 May;48(5):409-15. doi: 10.1002/mrc.2588.

PMID:
20301093
20.

Antimycobacterial activity of lichen substances.

Honda NK, Pavan FR, Coelho RG, de Andrade Leite SR, Micheletti AC, Lopes TI, Misutsu MY, Beatriz A, Brum RL, Leite CQ.

Phytomedicine. 2010 Apr;17(5):328-32. doi: 10.1016/j.phymed.2009.07.018. Epub 2009 Aug 14.

PMID:
19683421
21.

Biotransformation of a cage-like diels-alder adduct and derivatives by Mucor ramosissimus samutsevitsch.

Ito FM, Mena AE, Marques MR, de Lima DP, Beatriz A.

Braz J Microbiol. 2009 Jul;40(3):563-8. doi: 10.1590/S1517-838220090003000019. Epub 2009 Sep 1.

22.

A diaryl sulfide, sulfoxide, and sulfone bearing structural similarities to combretastatin A-4.

Barbosa EG, Bega LA, Beatriz A, Sarkar T, Hamel E, do Amaral MS, de Lima DP.

Eur J Med Chem. 2009 Jun;44(6):2685-8. doi: 10.1016/j.ejmech.2008.12.018. Epub 2008 Dec 25.

23.

Synthesis and biological evaluation of cytotoxic properties of stilbene-based resveratrol analogs.

de Lima DP, Rotta R, Beatriz A, Marques MR, Montenegro RC, Vasconcellos MC, Pessoa C, de Moraes MO, Costa-Lotufo LV, Frankland Sawaya AC, Eberlin MN.

Eur J Med Chem. 2009 Feb;44(2):701-7. doi: 10.1016/j.ejmech.2008.05.003. Epub 2008 May 15.

PMID:
18586355
24.

Synthesis of 1-methyl-3-oxo-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid methyl ester.

Aragão V, Constantino MG, Beatriz A, José da Silva GV.

Molecules. 2005 Nov 30;10(11):1413-8.

26.

Synthesis and biological evaluation of rigid polycyclic derivatives of the Diels-Alder adduct tricyclo[6.2.1.02,7]undeca-4,9-dien-3,6-dione.

Ito FM, Petroni JM, de Lima DP, Beatriz A, Marques MR, de Moraes MO, Costa-Lotufo LV, Montenegro RC, Magalhães HI, Pessoa Cdo O.

Molecules. 2007 Feb 27;12(2):271-82.

27.

Two polycyclic compounds derived from a Diels-Alder reaction.

Zukerman-Schpector J, Caracelli I, Vega M, Constantino MG, Beatriz A, da Silva GV.

Acta Crystallogr C. 2001 May;57(Pt 5):646-8. Epub 2001 May 15.

PMID:
11353280
28.

Epidural regional hypothermia for prevention of paraplegia after aortic occlusion: experimental evaluation in a rabbit model.

Gonzalez-Fajardo J, Beatriz A, Perez-Burkhardt JL, Alvarez T, Fernandez L, Ramos G, Vaquero C.

J Vasc Surg. 1996 Mar;23(3):446-52.

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