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Are environmental factors for atopic eczema in ISAAC Phase Three due to reverse causation?

Rutter C, Silverwood RJ, Williams HC, Ellwood P, Asher I, Garcia-Marcos L, Strachan DP, Pearce N, Langan SM; ISAAC Phase Three Study Group, Aït-Khaled N, Anderson HR, Asher MI, Beasley R, Björkstén B, Brunekreef B, Crane J, Ellwood P, Flohr C, Forastiere F, García-Marcos L, Foliaki S, Keil U, Lai CKW, Mallol J, Robertson CF, Mitchell EA, Montefort S, Odhiambo J, Pearce N, Shah J, Stewart AW, Strachan D, von Mutius E, Weiland SK, Weinmayr G, Williams H, Wong G.

J Invest Dermatol. 2018 Dec 3. pii: S0022-202X(18)32812-4. doi: 10.1016/j.jid.2018.08.035. [Epub ahead of print]


The further paradoxes of asthma management: time for a new approach across the spectrum of asthma severity.

Beasley R, Bird G, Harper J, Weatherall M.

Eur Respir J. 2018 Nov 1;52(5). pii: 1800694. doi: 10.1183/13993003.00694-2018. Print 2018 Nov. No abstract available.


Oxygen versus air-driven nebulisers for exacerbations of chronic obstructive pulmonary disease: a randomised controlled trial.

Bardsley G, Pilcher J, McKinstry S, Shirtcliffe P, Berry J, Fingleton J, Weatherall M, Beasley R.

BMC Pulm Med. 2018 Oct 3;18(1):157. doi: 10.1186/s12890-018-0720-7.


Increased risk of mortality with liberal oxygen therapy compared with conservative oxygen therapy in critically ill adults.

Beasley R, Mackle D.

BMJ Evid Based Med. 2018 Sep 28. pii: bmjebm-2018-111054. doi: 10.1136/bmjebm-2018-111054. [Epub ahead of print] No abstract available.


Triaging treatable traits in asthma.

Baggott C, Beasley R.

Respirology. 2018 Sep 19. doi: 10.1111/resp.13406. [Epub ahead of print] No abstract available.


A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): study protocol.

Young PJ, Bagshaw SM, Forbes A, Nichol A, Wright SE, Bellomo R, Bailey MJ, Beasley RW, Eastwood GM, Festa M, Gattas D, van Haren F, Litton E, Mouncey PR, Navarra L, Pilcher D, Mackle DM, McArthur CJ, McGuinness SP, Saxena MK, Webb S, Rowan KM; Australian and New Zealand Intensive Care Society Clinical Trials Group on behalf of the PEPTIC investigators.

Crit Care Resusc. 2018 Sep;20(3):182-189.


Cadmium level and severity of peripheral artery disease in patients with coronary artery disease.

Ujueta F, Arenas IA, Diaz D, Yates T, Beasley R, Navas-Acien A, Lamas GA.

Eur J Prev Cardiol. 2018 Aug 28:2047487318796585. doi: 10.1177/2047487318796585. [Epub ahead of print] No abstract available.


Serum periostin levels following small bone fractures, long bone fractures and joint replacements: an observational study.

Varughese R, Semprini R, Munro C, Fingleton J, Holweg C, Weatherall M, Beasley R, Braithwaite I.

Allergy Asthma Clin Immunol. 2018 Jul 26;14:30. doi: 10.1186/s13223-018-0254-9. eCollection 2018.


Change in biomarkers of type-2 inflammation following severe exacerbations of asthma.

Semprini R, Shortt N, Ebmeier S, Semprini A, Varughese R, Holweg CTJ, Matthews JG, Fingleton J, Weatherall M, Beasley R, Braithwaite I.

Thorax. 2018 Jul 18. pii: thoraxjnl-2018-211657. doi: 10.1136/thoraxjnl-2018-211657. [Epub ahead of print]


Anti-inflammatory duration of action of fluticasone furoate/vilanterol trifenatate in asthma: a cross-over randomised controlled trial.

Bardsley G, Daley-Yates P, Baines A, Kempsford R, Williams M, Mallon T, Braithwaite I, Riddell K, Joshi S, Bareille P, Beasley R, Fingleton J; study team.

Respir Res. 2018 Jul 13;19(1):133. doi: 10.1186/s12931-018-0836-6.


Obesity, underweight and BMI distribution characteristics of children by gross national income and income inequality: results from an international survey.

Murphy R, Stewart AW, Hancox RJ, Wall CR, Braithwaite I, Beasley R, Mitchell EA; ISAAC Phase Three Study Group.

Obes Sci Pract. 2018 May 17;4(3):216-228. doi: 10.1002/osp4.169. eCollection 2018 Jun.


Effect of active temperature management on mortality in intensive care unit patients.

Dallimore J, Ebmeier S, Thayabaran D, Bellomo R, Bernard G, Schortgen F, Saxena M, Beasley R, Weatherall M, Young P.

Crit Care Resusc. 2018 Jun;20(2):150-163. Review.


Pragmatic randomised clinical trials using electronic health records: general practitioner views on a model of a priori consent.

Hills T, Semprini A, Beasley R.

Trials. 2018 May 16;19(1):278. doi: 10.1186/s13063-018-2658-8.


Factors associated with body mass index in children and adolescents: An international cross-sectional study.

Mitchell EA, Stewart AW, Braithwaite I, Murphy R, Hancox RJ, Wall C, Beasley R; ISAAC Phase Three Study Group.

PLoS One. 2018 May 2;13(5):e0196221. doi: 10.1371/journal.pone.0196221. eCollection 2018.


A two centre observational study of simultaneous pulse oximetry and arterial oxygen saturation recordings in intensive care unit patients.

Ebmeier SJ, Barker M, Bacon M, Beasley RC, Bellomo R, Knee Chong C, Eastwood GM, Gilchrist J, Kagaya H, Pilcher J, Reddy SK, Ridgeon E, Sarma N, Sprogis S, Tanaka A, Tweedie M, Weatherall M, Young PJ.

Anaesth Intensive Care. 2018 May;46(3):297-303. Erratum in: Anaesth Intensive Care. 2018 Jul;46(4):432.


A feasibility study: association between gut microbiota enterotype and antibody response to seasonal trivalent influenza vaccine in adults.

Shortt N, Poyntz H, Young W, Jones A, Gestin A, Mooney A, Thayabaran D, Sparks J, Ostapowicz T, Tay A, Poppitt S, Elliott S, Wakefield G, Parry-Strong A, Ralston J, Gasser O, Beasley R, Weatherall M, Braithwaite I, Forbes-Blom E.

Clin Transl Immunology. 2018 Mar 29;7(3):e1013. doi: 10.1002/cti2.1013. eCollection 2018.


Type 2 Biomarkers and Prediction of Future Exacerbations and Lung Function Decline in Adult Asthma.

Semprini R, Williams M, Semprini A, McDouall A, Fingleton J, Holweg C, Weatherall M, Beasley R, Braithwaite I.

J Allergy Clin Immunol Pract. 2018 Nov - Dec;6(6):1982-1988.e1. doi: 10.1016/j.jaip.2018.03.004. Epub 2018 Mar 30.


Randomised controlled trial of rhinothermy for treatment of the common cold: a feasibility study.

Hei SV, McKinstry S, Bardsley G, Weatherall M, Beasley R, Fingleton J.

BMJ Open. 2018 Mar 27;8(3):e019350. doi: 10.1136/bmjopen-2017-019350.


Association between Frequency of Consumption of Fruit, Vegetables, Nuts and Pulses and BMI: Analyses of the International Study of Asthma and Allergies in Childhood (ISAAC).

Wall CR, Stewart AW, Hancox RJ, Murphy R, Braithwaite I, Beasley R, Mitchell EA; ISAAC Phase Three Study Group.

Nutrients. 2018 Mar 7;10(3). pii: E316. doi: 10.3390/nu10030316.


Protocol summary and statistical analysis plan for the intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX).

Mackle DM, Bailey MJ, Beasley RW, Bellomo R, Bennett VL, Deane AM, Eastwood GM, Finfer S, Freebairn RC, Litton E, Linke NJ, McArthur CJ, McGuinness SP, Panwar R, Young PJ; Australian and New Zealand Intensive Care Society Clinical Trials Group.

Crit Care Resusc. 2018 Mar;20(1):22-32.


Starting beta-blockers during exacerbations of chronic obstructive pulmonary disease.

Hancox RJ, Chang CL, Beasley R, Jenkins C.

Intern Med J. 2018 Feb;48(2):227-228. doi: 10.1111/imj.13695. No abstract available.


Gaming: a 21st century variant of seated immobility thromboembolism.

Braithwaite I, Shirtcliffe P, Jurevics R, Beasley R.

N Z Med J. 2018 Feb 2;131(1469):66-68. No abstract available.


The inhaled corticosteroid/long-acting β-agonist maintenance and reliever therapy regimen: where to from here?

Beasley R, Braithwaite I, Fingleton J, Weatherall M.

Eur Respir J. 2018 Jan 4;51(1). pii: 1702338. doi: 10.1183/13993003.02338-2017. Print 2018 Jan. No abstract available.


Phenotypes of symptomatic airways disease in China and New Zealand.

Fingleton J, Huang K, Weatherall M, Guo Y, Ivanov S, Bruijnzeel P, Zhang H, Wang W, Beasley R, Wang C; NZ–China Study Group.

Eur Respir J. 2017 Dec 7;50(6). pii: 1700957. doi: 10.1183/13993003.00957-2017. Print 2017 Dec.


Intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX): results of the pilot phase.

Young PJ, Mackle DM, Bailey MJ, Beasley RW, Bennett VL, Deane AM, Eastwood GM, Finfer S, Freebairn RC, Litton E, Linke NJ, McArthur CJ, McGuinness SP, Panwar R, Bellomo R; The ICU-ROX pilot investigators ; The Australian and New Zealand Intensive Care Society Clinical Trials Group .

Crit Care Resusc. 2017 Dec;19(4):344-354.


New Zealand asthma guidelines updated.

Beasley R, Hancox RJ.

N Z Med J. 2017 Dec 1;130(1466):7-9. No abstract available.


High flow or titrated oxygen for obese medical inpatients: a randomised crossover trial.

Pilcher J, Richards M, Eastlake L, McKinstry SJ, Bardsley G, Jefferies S, Braithwaite I, Weatherall M, Beasley R.

Med J Aust. 2017 Nov 20;207(10):430-434.


Description of the protocol for the PRACTICAL study: a randomised controlled trial of the efficacy and safety of ICS/LABA reliever therapy in asthma.

Fingleton J, Hardy J, Baggott C, Pilcher J, Corin A, Hancox RJ, Harwood M, Holliday M, Reddel HK, Shirtcliffe P, Snively S, Weatherall M, Beasley R.

BMJ Open Respir Res. 2017 Jul 29;4(1):e000217. doi: 10.1136/bmjresp-2017-000217. eCollection 2017.


Precision medicine in airway diseases: moving to clinical practice.

Agustí A, Bafadhel M, Beasley R, Bel EH, Faner R, Gibson PG, Louis R, McDonald VM, Sterk PJ, Thomas M, Vogelmeier C, Pavord ID; on behalf of all participants in the seminar.

Eur Respir J. 2017 Oct 19;50(4). pii: 1701655. doi: 10.1183/13993003.01655-2017. Print 2017 Oct.


Treatable traits of chronic airways disease.

Fingleton J, Hardy J, Beasley R.

Curr Opin Pulm Med. 2018 Jan;24(1):24-31. doi: 10.1097/MCP.0000000000000445. Review.


Vitamin D and asthma: a case to answer.

Beasley R, Weatherall M.

Lancet Respir Med. 2017 Nov;5(11):839-840. doi: 10.1016/S2213-2600(17)30346-6. Epub 2017 Oct 3. No abstract available.


Oseltamivir, amantadine, and ribavirin combination antiviral therapy versus oseltamivir monotherapy for the treatment of influenza: a multicentre, double-blind, randomised phase 2 trial.

Beigel JH, Bao Y, Beeler J, Manosuthi W, Slandzicki A, Dar SM, Panuto J, Beasley RL, Perez-Patrigeon S, Suwanpimolkul G, Losso MH, McClure N, Bozzolo DR, Myers C, Holley HP Jr, Hoopes J, Lane HC, Hughes MD, Davey RT; IRC003 Study Team.

Lancet Infect Dis. 2017 Dec;17(12):1255-1265. doi: 10.1016/S1473-3099(17)30476-0. Epub 2017 Sep 22.


Nasal high flow therapy and PtCO2 in stable COPD: A randomized controlled cross-over trial.

McKinstry S, Pilcher J, Bardsley G, Berry J, Van de Hei S, Braithwaite I, Fingleton J, Weatherall M, Beasley R.

Respirology. 2018 Apr;23(4):378-384. doi: 10.1111/resp.13185. Epub 2017 Sep 22.


After asthma: redefining airways diseases.

Pavord ID, Beasley R, Agusti A, Anderson GP, Bel E, Brusselle G, Cullinan P, Custovic A, Ducharme FM, Fahy JV, Frey U, Gibson P, Heaney LG, Holt PG, Humbert M, Lloyd CM, Marks G, Martinez FD, Sly PD, von Mutius E, Wenzel S, Zar HJ, Bush A.

Lancet. 2018 Jan 27;391(10118):350-400. doi: 10.1016/S0140-6736(17)30879-6. Epub 2017 Sep 11. Review. No abstract available.


Asthma prescribing: Where are we headed?

Beasley R, Hardy J, Hancox R.

Respirology. 2017 Nov;22(8):1487-1488. doi: 10.1111/resp.13159. Epub 2017 Aug 27. No abstract available.


Trends in international asthma mortality: analysis of data from the WHO Mortality Database from 46 countries (1993-2012).

Ebmeier S, Thayabaran D, Braithwaite I, Bénamara C, Weatherall M, Beasley R.

Lancet. 2017 Sep 2;390(10098):935-945. doi: 10.1016/S0140-6736(17)31448-4. Epub 2017 Aug 7.


Protocol for a randomised controlled trial of 90% kanuka honey versus 5% aciclovir for the treatment of herpes simplex labialis in the community setting.

Semprini A, Singer J, Shortt N, Braithwaite I, Beasley R; Pharmacy Research Network.

BMJ Open. 2017 Aug 3;7(8):e017766. doi: 10.1136/bmjopen-2017-017766.


Effect of 0.9% Saline or Plasma-Lyte 148 as Crystalloid Fluid Therapy in the Intensive Care Unit on Blood Product Use and Postoperative Bleeding After Cardiac Surgery.

Reddy SK, Bailey MJ, Beasley RW, Bellomo R, Mackle DM, Psirides AJ, Young PJ.

J Cardiothorac Vasc Anesth. 2017 Oct;31(5):1630-1638. doi: 10.1053/j.jvca.2017.04.023. Epub 2017 Apr 15.


Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial.

Pilcher J, Patel M, Pritchard A, Thayabaran D, Ebmeier S, Shaw D, Black P, Braithwaite I, Weatherall M, Beasley R.

NPJ Prim Care Respir Med. 2017 May 11;27(1):33. doi: 10.1038/s41533-017-0032-z.


Body mass index and vigorous physical activity in children and adolescents: an international cross-sectional study.

Braithwaite IE, Stewart AW, Hancox RJ, Murphy R, Wall CR, Beasley R, Mitchell EA; ISAAC Phase Three Study Group.

Acta Paediatr. 2017 Aug;106(8):1323-1330. doi: 10.1111/apa.13903. Epub 2017 Jun 6.


Physiological effects of titrated oxygen via nasal high-flow cannulae in COPD exacerbations: A randomized controlled cross-over trial.

Pilcher J, Eastlake L, Richards M, Power S, Cripps T, Bibby S, Braithwaite I, Weatherall M, Beasley R.

Respirology. 2017 Aug;22(6):1149-1155. doi: 10.1111/resp.13050. Epub 2017 May 4.


Lack of Association Between Limb Hemodynamics and Response to Infrapopliteal Endovascular Therapy in Patients With Critical Limb Ischemia.

Mustapha JA, Diaz-Sandoval LJ, Adams G, Jaff MR, Beasley R, McGoff T, Finton S, Miller LE, Ansari M, Saab F.

J Invasive Cardiol. 2017 May;29(5):175-180.


RCT of the effect of berryfruit polyphenolic cultivar extract in mild steroid-naive asthma: a cross-over, placebo-controlled study.

Power S, Williams M, Semprini A, Munro C, Caswell-Smith R, Pilcher J, Holliday M, Fingleton J, Harper J, Hurst R, Weatherall M, Beasley R, Braithwaite I.

BMJ Open. 2017 Mar 20;7(3):e013850. doi: 10.1136/bmjopen-2016-013850.


Protocol and statistical analysis plan for the Randomised Evaluation of Active Control of Temperature versus Ordinary Temperature Management (REACTOR) trial.

Young PJ, Bailey MJ, Beasley RW, Freebairn RC, Hammond NE, Haren FM, Harward ML, Henderson SJ, Mackle DM, McArthur CJ, McGuinness SP, Myburgh JA, Saxena MK, Turner A, Webb SA, Bellomo R; The ANZICS Clinical Trials Group .

Crit Care Resusc. 2017 Mar;19(1):81-87.


Day-time variation of serum periostin in asthmatic adults treated with ICS/LABA and adults without asthma.

Caswell-Smith R, Cripps T, Charles T, Hosking A, Handigol M, Holweg C, Matthews J, Holliday M, Maillot C, Fingleton J, Weatherall M, Beasley R, Braithwaite I; Periostin Study Team.

Allergy Asthma Clin Immunol. 2017 Feb 8;13:8. doi: 10.1186/s13223-017-0182-0. eCollection 2017.


β-blockers in exacerbations of COPD: feasibility of a randomised controlled trial.

Chang CL, Wong C, Beckert L, Shafuddin E, Beasley R, Young R, Hancox RJ.

ERJ Open Res. 2017 Jan 17;3(1). pii: 00090-2016. doi: 10.1183/23120541.00090-2016. eCollection 2017 Jan.


Sing Your Lungs Out-a community singing group for chronic obstructive pulmonary disease: a 1-year pilot study.

McNaughton A, Weatherall M, Williams M, McNaughton H, Aldington S, Williams G, Beasley R.

BMJ Open. 2017 Jan 24;7(1):e014151. doi: 10.1136/bmjopen-2016-014151.


Longitudinal variation of serum periostin levels in adults with stable asthma.

Semprini R, Caswell-Smith R, Fingleton J, Holweg C, Matthews J, Weatherall M, Beasley R, Braithwaite I; Periostin Study Team.

J Allergy Clin Immunol. 2017 May;139(5):1687-1688.e9. doi: 10.1016/j.jaci.2016.11.041. Epub 2017 Jan 16. No abstract available.


Adult asthma quick reference guides: Trans-Tasman differences in opinion.

Beasley R, Thayabaran D, Hancox RJ.

Respirology. 2017 Jan;22(1):9-11. doi: 10.1111/resp.12935. Epub 2016 Nov 29. No abstract available.


Asthma and Respiratory Foundation NZ adult asthma guidelines: a quick reference guide.

Beasley R, Hancox RJ, Harwood M, Perrin K, Poot B, Pilcher J, Reid J, Talemaitoga A, Thayabaran D.

N Z Med J. 2016 Nov 18;129(1445):83-102.


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