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Items: 17

1.

A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis.

Love MS, Beasley FC, Jumani RS, Wright TM, Chatterjee AK, Huston CD, Schultz PG, McNamara CW.

PLoS Negl Trop Dis. 2017 Feb 3;11(2):e0005373. doi: 10.1371/journal.pntd.0005373. eCollection 2017 Feb.

2.

Nitric Oxide Synthase as a Target for Methicillin-Resistant Staphylococcus aureus.

Holden JK, Kang S, Beasley FC, Cinelli MA, Li H, Roy SG, Dejam D, Edinger AL, Nizet V, Silverman RB, Poulos TL.

Chem Biol. 2015 Jun 18;22(6):785-92. doi: 10.1016/j.chembiol.2015.05.013.

3.

Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection.

Lin AE, Beasley FC, Olson J, Keller N, Shalwitz RA, Hannan TJ, Hultgren SJ, Nizet V.

PLoS Pathog. 2015 Apr 30;11(4):e1004818. doi: 10.1371/journal.ppat.1004818. eCollection 2015 Apr.

4.

A group A Streptococcus ADP-ribosyltransferase toxin stimulates a protective interleukin 1β-dependent macrophage immune response.

Lin AE, Beasley FC, Keller N, Hollands A, Urbano R, Troemel ER, Hoffman HM, Nizet V.

mBio. 2015 Mar 10;6(2):e00133. doi: 10.1128/mBio.00133-15.

5.

A Staphylococcus aureus TIR domain protein virulence factor blocks TLR2-mediated NF-κB signaling.

Askarian F, van Sorge NM, Sangvik M, Beasley FC, Henriksen JR, Sollid JU, van Strijp JA, Nizet V, Johannessen M.

J Innate Immun. 2014;6(4):485-98. doi: 10.1159/000357618. Epub 2014 Jan 25.

6.

Group B Streptococcus engages an inhibitory Siglec through sialic acid mimicry to blunt innate immune and inflammatory responses in vivo.

Chang YC, Olson J, Beasley FC, Tung C, Zhang J, Crocker PR, Varki A, Nizet V.

PLoS Pathog. 2014 Jan;10(1):e1003846. doi: 10.1371/journal.ppat.1003846. Epub 2014 Jan 2.

7.

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, Frezza C, Bernard NJ, Kelly B, Foley NH, Zheng L, Gardet A, Tong Z, Jany SS, Corr SC, Haneklaus M, Caffrey BE, Pierce K, Walmsley S, Beasley FC, Cummins E, Nizet V, Whyte M, Taylor CT, Lin H, Masters SL, Gottlieb E, Kelly VP, Clish C, Auron PE, Xavier RJ, O'Neill LA.

Nature. 2013 Apr 11;496(7444):238-42. doi: 10.1038/nature11986. Epub 2013 Mar 24.

8.

Methicillin-resistant Staphylococcus aureus bacterial nitric-oxide synthase affects antibiotic sensitivity and skin abscess development.

van Sorge NM, Beasley FC, Gusarov I, Gonzalez DJ, von Köckritz-Blickwede M, Anik S, Borkowski AW, Dorrestein PC, Nudler E, Nizet V.

J Biol Chem. 2013 Mar 1;288(9):6417-26. doi: 10.1074/jbc.M112.448738. Epub 2013 Jan 15.

9.

E622, a miniature, virulence-associated mobile element.

Stavrinides J, Kirzinger MW, Beasley FC, Guttman DS.

J Bacteriol. 2012 Jan;194(2):509-17. doi: 10.1128/JB.06211-11. Epub 2011 Nov 11.

10.

Mutation of L-2,3-diaminopropionic acid synthase genes blocks staphyloferrin B synthesis in Staphylococcus aureus.

Beasley FC, Cheung J, Heinrichs DE.

BMC Microbiol. 2011 Sep 9;11:199. doi: 10.1186/1471-2180-11-199.

11.
12.

Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulence.

Wyatt MA, Wang W, Roux CM, Beasley FC, Heinrichs DE, Dunman PM, Magarvey NA.

Science. 2010 Jul 16;329(5989):294-6. doi: 10.1126/science.1188888. Epub 2010 Jun 3. Erratum in: Science. 2011 Sep 9;333(6048):1381.

13.

Staphylococcus aureus fur regulates the expression of virulence factors that contribute to the pathogenesis of pneumonia.

Torres VJ, Attia AS, Mason WJ, Hood MI, Corbin BD, Beasley FC, Anderson KL, Stauff DL, McDonald WH, Zimmerman LJ, Friedman DB, Heinrichs DE, Dunman PM, Skaar EP.

Infect Immun. 2010 Apr;78(4):1618-28. doi: 10.1128/IAI.01423-09. Epub 2010 Jan 25.

14.

Siderophore-mediated iron acquisition in the staphylococci.

Beasley FC, Heinrichs DE.

J Inorg Biochem. 2010 Mar;104(3):282-8. doi: 10.1016/j.jinorgbio.2009.09.011. Epub 2009 Sep 26. Review.

PMID:
19850350
15.

Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus.

Cheung J, Beasley FC, Liu S, Lajoie GA, Heinrichs DE.

Mol Microbiol. 2009 Nov;74(3):594-608. doi: 10.1111/j.1365-2958.2009.06880.x. Epub 2009 Sep 22.

16.

Characterization of staphyloferrin A biosynthetic and transport mutants in Staphylococcus aureus.

Beasley FC, Vinés ED, Grigg JC, Zheng Q, Liu S, Lajoie GA, Murphy ME, Heinrichs DE.

Mol Microbiol. 2009 May;72(4):947-63. doi: 10.1111/j.1365-2958.2009.06698.x. Epub 2009 Apr 14.

17.

Receptor-interacting protein-2 deficiency delays macrophage migration and increases intracellular infection during peritoneal dialysis-associated peritonitis.

McCully ML, Fairhead T, Colmont CS, Beasley FC, Heinrichs DE, Blake PG, Topley N, Madrenas J.

Am J Nephrol. 2008;28(6):879-89. doi: 10.1159/000141041. Epub 2008 Jun 20.

PMID:
18566542

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