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Items: 1 to 50 of 269

1.

Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome.

Asiminas A, Jackson AD, Louros SR, Till SM, Spano T, Dando O, Bear MF, Chattarji S, Hardingham GE, Osterweil EK, Wyllie DJA, Wood ER, Kind PC.

Sci Transl Med. 2019 May 29;11(494). pii: eaao0498. doi: 10.1126/scitranslmed.aao0498.

PMID:
31142675
2.

How Do You Get Citizen Scientists to Dive with Sharks?

Bear M.

Narrat Inq Bioeth. 2019;9(1):6-8. doi: 10.1353/nib.2019.0004. No abstract available.

PMID:
31031277
3.

Full Collection of Personal Narratives.

Soutar IF, Bear M, Savoie H, Farmer L, Bélisle-Pipon JC, Grande CD, Rouleau G, Thiagarajan S, Wacha S, Lee AM, Bressler DW, Jackson JK, Ehrhart MJ, Arscott DB, Nguyen KA, Michelucci P, Hastings JJ, Nichols M, Nuñez-Farias P, Velásquez-Contreras S, Ríos-Carmona V, Velásquez-Contreras J, Velásquez-Contreras AE, Rojas-Rojas JL, Riveros-Flores B, Hulbert J, Santos-Lang C.

Narrat Inq Bioeth. 2019;9(1):4-34. doi: 10.1353/nib.2019.0002. No abstract available.

PMID:
31031275
4.

In memoriam: John Lisman - commentaries on CaMKII as a memory molecule.

Bear MF, Cooke SF, Giese KP, Kaang BK, Kennedy MB, Kim JI, Morris RGM, Park P.

Mol Brain. 2018 Dec 28;11(1):76. doi: 10.1186/s13041-018-0419-y.

5.

Neuroanatomy, Hypothalamus.

Bear MH, Bollu PC.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2019 Jan 13.

6.

The mouse as a model for neuropsychiatric drug development.

Howe JR 6th, Bear MF, Golshani P, Klann E, Lipton SA, Mucke L, Sahin M, Silva AJ.

Curr Biol. 2018 Sep 10;28(17):R909-R914. doi: 10.1016/j.cub.2018.07.046.

7.

Consecutive Day HSP90 Inhibitor Administration Improves Efficacy in Murine Models of KIT-Driven Malignancies and Canine Mast Cell Tumors.

London CA, Acquaviva J, Smith DL, Sequeira M, Ogawa LS, Gardner HL, Bernabe LF, Bear MD, Bechtel SA, Proia DA.

Clin Cancer Res. 2018 Dec 15;24(24):6396-6407. doi: 10.1158/1078-0432.CCR-18-0703. Epub 2018 Aug 31.

8.

Interneuron Simplification and Loss of Structural Plasticity As Markers of Aging-Related Functional Decline.

Eavri R, Shepherd J, Welsh CA, Flanders GH, Bear MF, Nedivi E.

J Neurosci. 2018 Sep 26;38(39):8421-8432. doi: 10.1523/JNEUROSCI.0808-18.2018. Epub 2018 Aug 14.

9.

Phase I/II evaluation of RV1001, a novel PI3Kδ inhibitor, in spontaneous canine lymphoma.

Gardner HL, Rippy SB, Bear MD, Cronin KL, Heeb H, Burr H, Cannon CM, Penmetsa KV, Viswanadha S, Vakkalanka S, London CA.

PLoS One. 2018 Apr 24;13(4):e0195357. doi: 10.1371/journal.pone.0195357. eCollection 2018.

10.

Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome.

Berry-Kravis EM, Lindemann L, Jønch AE, Apostol G, Bear MF, Carpenter RL, Crawley JN, Curie A, Des Portes V, Hossain F, Gasparini F, Gomez-Mancilla B, Hessl D, Loth E, Scharf SH, Wang PP, Von Raison F, Hagerman R, Spooren W, Jacquemont S.

Nat Rev Drug Discov. 2018 Apr;17(4):280-299. doi: 10.1038/nrd.2017.221. Epub 2017 Dec 8. Review.

PMID:
29217836
11.

The Economy of Shark Conservation in the Northeast Pacific: The Role of Ecotourism and Citizen Science.

Mieras PA, Harvey-Clark C, Bear M, Hodgin G, Hodgin B.

Adv Mar Biol. 2017;78:121-153. doi: 10.1016/bs.amb.2017.08.003. Epub 2017 Sep 21.

PMID:
29056141
12.

Recovery from the anatomical effects of long-term monocular deprivation in cat lateral geniculate nucleus.

Duffy KR, Fong MF, Mitchell DE, Bear MF.

J Comp Neurol. 2018 Feb 1;526(2):310-323. doi: 10.1002/cne.24336. Epub 2017 Oct 27.

PMID:
29023717
13.

Improving admission medication reconciliation with pharmacists or pharmacy technicians in the emergency department: a randomised controlled trial.

Pevnick JM, Nguyen C, Jackevicius CA, Palmer KA, Shane R, Cook-Wiens G, Rogatko A, Bear M, Rosen O, Seki D, Doyle B, Desai A, Bell DS.

BMJ Qual Saf. 2018 Jul;27(7):512-520. doi: 10.1136/bmjqs-2017-006761. Epub 2017 Oct 6.

14.

R-Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice.

Stoppel LJ, Kazdoba TM, Schaffler MD, Preza AR, Heynen A, Crawley JN, Bear MF.

Neuropsychopharmacology. 2018 Feb;43(3):513-524. doi: 10.1038/npp.2017.236. Epub 2017 Oct 6.

15.

Experience-Dependent Synaptic Plasticity in V1 Occurs without Microglial CX3CR1.

Schecter RW, Maher EE, Welsh CA, Stevens B, Erisir A, Bear MF.

J Neurosci. 2017 Nov 1;37(44):10541-10553. doi: 10.1523/JNEUROSCI.2679-16.2017. Epub 2017 Sep 26.

16.

Arc restores juvenile plasticity in adult mouse visual cortex.

Jenks KR, Kim T, Pastuzyn ED, Okuno H, Taibi AV, Bito H, Bear MF, Shepherd JD.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9182-9187. doi: 10.1073/pnas.1700866114. Epub 2017 Aug 8.

17.

Arbaclofen in fragile X syndrome: results of phase 3 trials.

Berry-Kravis E, Hagerman R, Visootsak J, Budimirovic D, Kaufmann WE, Cherubini M, Zarevics P, Walton-Bowen K, Wang P, Bear MF, Carpenter RL.

J Neurodev Disord. 2017 Jun 12;9:3. doi: 10.1186/s11689-016-9181-6. eCollection 2017.

18.

β-Arrestin2 Couples Metabotropic Glutamate Receptor 5 to Neuronal Protein Synthesis and Is a Potential Target to Treat Fragile X.

Stoppel LJ, Auerbach BD, Senter RK, Preza AR, Lefkowitz RJ, Bear MF.

Cell Rep. 2017 Mar 21;18(12):2807-2814. doi: 10.1016/j.celrep.2017.02.075.

19.

Pharmacist Counseling and the Use of Nonsteroidal Anti-Inflammatory Drugs by Older Adults.

Bear MD, Bartlett D, Evans P.

Consult Pharm. 2017 Mar 1;32(3):161-168. doi: 10.4140/TCP.n.2017.161.

PMID:
28270271
20.

Negative Allosteric Modulation of mGluR5 Partially Corrects Pathophysiology in a Mouse Model of Rett Syndrome.

Tao J, Wu H, Coronado AA, de Laittre E, Osterweil EK, Zhang Y, Bear MF.

J Neurosci. 2016 Nov 23;36(47):11946-11958.

21.

Rapid recovery from the effects of early monocular deprivation is enabled by temporary inactivation of the retinas.

Fong MF, Mitchell DE, Duffy KR, Bear MF.

Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):14139-14144. Epub 2016 Nov 17.

22.

Arbaclofen in Children and Adolescents with Autism Spectrum Disorder: A Randomized, Controlled, Phase 2 Trial.

Veenstra-VanderWeele J, Cook EH, King BH, Zarevics P, Cherubini M, Walton-Bowen K, Bear MF, Wang PP, Carpenter RL.

Neuropsychopharmacology. 2017 Jun;42(7):1390-1398. doi: 10.1038/npp.2016.237. Epub 2016 Oct 17.

23.

MiR-9 is overexpressed in spontaneous canine osteosarcoma and promotes a metastatic phenotype including invasion and migration in osteoblasts and osteosarcoma cell lines.

Fenger JM, Roberts RD, Iwenofu OH, Bear MD, Zhang X, Couto JI, Modiano JF, Kisseberth WC, London CA.

BMC Cancer. 2016 Oct 10;16(1):784.

24.

Urine metabolomic profiling of children with respiratory tract infections in the emergency department: a pilot study.

Adamko DJ, Saude E, Bear M, Regush S, Robinson JL.

BMC Infect Dis. 2016 Aug 22;16(1):439. doi: 10.1186/s12879-016-1709-6.

25.

Phase 3 Trials of Thermosensitive Ciprofloxacin Gel for Middle Ear Effusion in Children with Tubes.

Park AH, White DR, Moss JR, Bear M, LeBel C.

Otolaryngol Head Neck Surg. 2016 Aug;155(2):324-31. doi: 10.1177/0194599816645526. Epub 2016 May 17.

26.

Perspectives in Marine Citizen Science.

Bear M.

J Microbiol Biol Educ. 2016 Mar 1;17(1):56-9. doi: 10.1128/jmbe.v17i1.1037. eCollection 2016 Mar. Erratum in: J Microbiol Biol Educ. 2016 Dec 02;17 (3):505.

27.

Safety and Efficacy of Intratympanic Ciprofloxacin Otic Suspension in Children With Middle Ear Effusion Undergoing Tympanostomy Tube Placement: Two Randomized Clinical Trials.

Mair EA, Park AH, Don D, Koempel J, Bear M, LeBel C.

JAMA Otolaryngol Head Neck Surg. 2016 May 1;142(5):444-51. doi: 10.1001/jamaoto.2016.0001.

PMID:
26985629
28.

Contrasting roles for parvalbumin-expressing inhibitory neurons in two forms of adult visual cortical plasticity.

Kaplan ES, Cooke SF, Komorowski RW, Chubykin AA, Thomazeau A, Khibnik LA, Gavornik JP, Bear MF.

Elife. 2016 Mar 4;5. pii: e11450. doi: 10.7554/eLife.11450.

29.

Gene expression analysis in Fmr1KO mice identifies an immunological signature in brain tissue and mGluR5-related signaling in primary neuronal cultures.

Prilutsky D, Kho AT, Palmer NP, Bhakar AL, Smedemark-Margulies N, Kong SW, Margulies DM, Bear MF, Kohane IS.

Mol Autism. 2015 Dec 21;6:66. doi: 10.1186/s13229-015-0061-9. eCollection 2015.

30.

Convergence of Hippocampal Pathophysiology in Syngap+/- and Fmr1-/y Mice.

Barnes SA, Wijetunge LS, Jackson AD, Katsanevaki D, Osterweil EK, Komiyama NH, Grant SG, Bear MF, Nägerl UV, Kind PC, Wyllie DJ.

J Neurosci. 2015 Nov 11;35(45):15073-81. doi: 10.1523/JNEUROSCI.1087-15.2015.

31.

Metabotropic glutamate receptor signaling is required for NMDA receptor-dependent ocular dominance plasticity and LTD in visual cortex.

Sidorov MS, Kaplan ES, Osterweil EK, Lindemann L, Bear MF.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12852-7. doi: 10.1073/pnas.1512878112. Epub 2015 Sep 28.

32.

Alpha-Catulin Co-Localizes With Vimentin Intermediate Filaments and Functions in Pulmonary Vascular Endothelial Cell Migration via ROCK.

Bear MD, Liu T, Abualkhair S, Ghamloush MA, Hill NS, Preston I, Fanburg BL, Kayyali US, Toksoz D.

J Cell Physiol. 2016 Apr;231(4):934-43. doi: 10.1002/jcp.25185. Epub 2015 Sep 17.

PMID:
26377600
33.

Randomized Clinical Trial of a Sustained-Exposure Ciprofloxacin for Intratympanic Injection During Tympanostomy Tube Surgery.

Mair EA, Moss JR, Dohar JE, Antonelli PJ, Bear M, LeBel C.

Ann Otol Rhinol Laryngol. 2016 Feb;125(2):105-14. doi: 10.1177/0003489415599001. Epub 2015 Aug 20.

34.

Characterization of STAT3 expression, signaling and inhibition in feline oral squamous cell carcinoma.

Brown ME, Bear MD, Rosol TJ, Premanandan C, Kisseberth WC, London CA.

BMC Vet Res. 2015 Aug 14;11:206. doi: 10.1186/s12917-015-0505-7.

35.

Conserved hippocampal cellular pathophysiology but distinct behavioural deficits in a new rat model of FXS.

Till SM, Asiminas A, Jackson AD, Katsanevaki D, Barnes SA, Osterweil EK, Bear MF, Chattarji S, Wood ER, Wyllie DJ, Kind PC.

Hum Mol Genet. 2015 Nov 1;24(21):5977-84. doi: 10.1093/hmg/ddv299. Epub 2015 Aug 4.

36.

Visual recognition memory: a view from V1.

Cooke SF, Bear MF.

Curr Opin Neurobiol. 2015 Dec;35:57-65. doi: 10.1016/j.conb.2015.06.008. Epub 2015 Jul 4. Review.

37.

Erratum: Visual recognition memory, manifested as long-term habituation, requires synaptic plasticity in V1.

Cooke SF, Komorowski RW, Kaplan ES, Gavornik JP, Bear MF.

Nat Neurosci. 2015 Jun;18(6):926. doi: 10.1038/nn0615-926d. No abstract available.

PMID:
26007217
38.

Visual recognition memory, manifested as long-term habituation, requires synaptic plasticity in V1.

Cooke SF, Komorowski RW, Kaplan ES, Gavornik JP, Bear MF.

Nat Neurosci. 2015 Feb;18(2):262-71. doi: 10.1038/nn.3920. Epub 2015 Jan 19. Erratum in: Nat Neurosci. 2015 Jun;18(6):926.

39.

Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion.

Tian D, Stoppel LJ, Heynen AJ, Lindemann L, Jaeschke G, Mills AA, Bear MF.

Nat Neurosci. 2015 Feb;18(2):182-4. doi: 10.1038/nn.3911. Epub 2015 Jan 12.

40.

Evolution of Staphylococcus aureus under vancomycin selective pressure: the role of the small-colony variant phenotype.

Lenhard JR, von Eiff C, Hong IS, Holden PN, Bear MD, Suen A, Bulman ZP, Tsuji BT.

Antimicrob Agents Chemother. 2015 Feb;59(2):1347-51. doi: 10.1128/AAC.04508-14. Epub 2014 Dec 1.

41.

Microchip amplifier for in vitro, in vivo, and automated whole cell patch-clamp recording.

Harrison RR, Kolb I, Kodandaramaiah SB, Chubykin AA, Yang A, Bear MF, Boyden ES, Forest CR.

J Neurophysiol. 2015 Feb 15;113(4):1275-82. doi: 10.1152/jn.00629.2014. Epub 2014 Nov 26.

42.

Higher brain functions served by the lowly rodent primary visual cortex.

Gavornik JP, Bear MF.

Learn Mem. 2014 Sep 15;21(10):527-33. doi: 10.1101/lm.034355.114. Print 2014 Oct. Review.

43.

Biologic activity of the novel orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 against canine melanoma cell lines.

Breit MN, Kisseberth WC, Bear MD, Landesman Y, Kashyap T, McCauley D, Kauffman MG, Shacham S, London CA.

BMC Vet Res. 2014 Jul 15;10:160. doi: 10.1186/1746-6148-10-160.

44.

Extinction of an instrumental response: a cognitive behavioral assay in Fmr1 knockout mice.

Sidorov MS, Krueger DD, Taylor M, Gisin E, Osterweil EK, Bear MF.

Genes Brain Behav. 2014 Jun;13(5):451-8. doi: 10.1111/gbb.12137. Epub 2014 Apr 30.

45.

The effect of Burns & Wounds (B&W)/burdock leaf therapy on burn-injured Amish patients: a pilot study measuring pain levels, infection rates, and healing times.

Amish Burn Study Group, Kolacz NM, Jaroch MT, Bear ML, Hess RF.

J Holist Nurs. 2014 Dec;32(4):327-40. doi: 10.1177/0898010114525683. Epub 2014 Mar 25.

PMID:
24668061
46.

Learned spatiotemporal sequence recognition and prediction in primary visual cortex.

Gavornik JP, Bear MF.

Nat Neurosci. 2014 May;17(5):732-7. doi: 10.1038/nn.3683. Epub 2014 Mar 23.

47.

Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis.

Kong SW, Sahin M, Collins CD, Wertz MH, Campbell MG, Leech JD, Krueger D, Bear MF, Kunkel LM, Kohane IS.

Mol Autism. 2014 Feb 24;5(1):16. doi: 10.1186/2040-2392-5-16.

48.

Overexpression of miR-9 in mast cells is associated with invasive behavior and spontaneous metastasis.

Fenger JM, Bear MD, Volinia S, Lin TY, Harrington BK, London CA, Kisseberth WC.

BMC Cancer. 2014 Feb 11;14:84. doi: 10.1186/1471-2407-14-84.

49.

Preclinical evaluation of the novel, orally bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in spontaneous canine cancer: results of a phase I study.

London CA, Bernabe LF, Barnard S, Kisseberth WC, Borgatti A, Henson M, Wilson H, Jensen K, Ito D, Modiano JF, Bear MD, Pennell ML, Saint-Martin JR, McCauley D, Kauffman M, Shacham S.

PLoS One. 2014 Feb 4;9(2):e87585. doi: 10.1371/journal.pone.0087585. eCollection 2014.

50.

How the mechanisms of long-term synaptic potentiation and depression serve experience-dependent plasticity in primary visual cortex.

Cooke SF, Bear MF.

Philos Trans R Soc Lond B Biol Sci. 2013 Dec 2;369(1633):20130284. doi: 10.1098/rstb.2013.0284. Print 2014 Jan 5. Review. Erratum in: Philos Trans R Soc Lond B Biol Sci. 2014 Apr 5;369(1639):20140021.

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