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Items: 1 to 50 of 177

1.

Chromosome X loci and spontaneous granulosa cell tumor development in SWR mice: epigenetics and epistasis at work for an ovarian phenotype.

Dorward AM, Yaskowiak ES, Smith KN, Stanford KR, Shultz KL, Beamer WG.

Epigenetics. 2013 Feb;8(2):184-91. doi: 10.4161/epi.23399. Epub 2013 Jan 8.

2.

Fine map of the Gct1 spontaneous ovarian granulosa cell tumor locus.

Smith KN, Halfyard SJ, Yaskowiak ES, Shultz KL, Beamer WG, Dorward AM.

Mamm Genome. 2013 Feb;24(1-2):63-71. doi: 10.1007/s00335-012-9439-6. Epub 2012 Nov 18.

3.

A novel animal model for bone metastasis in human lung cancer.

Li M, Zhou M, Gong M, Ma J, Pei F, Beamer WG, Shultz LD, Hock JM, Yu X.

Oncol Lett. 2012 Apr 1;3(4):802-806. Epub 2012 Feb 1.

4.

Low magnitude mechanical signals mitigate osteopenia without compromising longevity in an aged murine model of spontaneous granulosa cell ovarian cancer.

Pagnotti GM, Adler BJ, Green DE, Chan ME, Frechette DM, Shroyer KR, Beamer WG, Rubin J, Rubin CT.

Bone. 2012 Sep;51(3):570-7. doi: 10.1016/j.bone.2012.05.004. Epub 2012 May 11.

5.

Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density.

Ackert-Bicknell CL, Demissie S, Tsaih SW, Beamer WG, Cupples LA, Paigen BJ, Hsu YH, Kiel DP, Karasik D.

Bone. 2012 May;50(5):1188-95. doi: 10.1016/j.bone.2012.01.011. Epub 2012 Jan 28.

6.

Bone morphogenetic protein receptor type Ia localization causes increased BMP2 signaling in mice exhibiting increased peak bone mass phenotype.

Bragdon B, Bonor J, Shultz KL, Beamer WG, Rosen CJ, Nohe A.

J Cell Physiol. 2012 Jul;227(7):2870-9. doi: 10.1002/jcp.23028.

7.

Altered plasma membrane dynamics of bone morphogenetic protein receptor type Ia in a low bone mass mouse model.

Bragdon B, D'Angelo A, Gurski L, Bonor J, Schultz KL, Beamer WG, Rosen CJ, Nohe A.

Bone. 2012 Jan;50(1):189-99. doi: 10.1016/j.bone.2011.10.016. Epub 2011 Oct 22.

8.

Multiple quantitative trait loci for cortical and trabecular bone regulation map to mid-distal mouse chromosome 4 that shares linkage homology to human chromosome 1p36.

Beamer WG, Shultz KL, Coombs HF 3rd, Horton LG, Donahue LR, Rosen CJ.

J Bone Miner Res. 2012 Jan;27(1):47-57. doi: 10.1002/jbmr.515.

9.

Insulin-like growth factor-1 increases bone calcium accumulation only during rapid growth in female rats.

Zhang Q, Wastney ME, Rosen CJ, Beamer WG, Weaver CM.

J Nutr. 2011 Nov;141(11):2010-6. doi: 10.3945/jn.111.142679. Epub 2011 Sep 28.

10.

Casein kinase 2 regulates in vivo bone formation through its interaction with bone morphogenetic protein receptor type Ia.

Bragdon B, Thinakaran S, Moseychuk O, Gurski L, Bonor J, Price C, Wang L, Beamer WG, Nohe A.

Bone. 2011 Nov;49(5):944-54. doi: 10.1016/j.bone.2011.06.037. Epub 2011 Jul 13.

PMID:
21763800
11.

An essential role for the association of CD47 to SHPS-1 in skeletal remodeling.

Maile LA, DeMambro VE, Wai C, Lotinun S, Aday AW, Capps BE, Beamer WG, Rosen CJ, Clemmons DR.

J Bone Miner Res. 2011 Sep;26(9):2068-81. doi: 10.1002/jbmr.441. Erratum in: J Bone Miner Res. 2011 Nov;26(11):2792. Lotinun, Sutada [added].

12.

The heparin-binding domain of IGFBP-2 has insulin-like growth factor binding-independent biologic activity in the growing skeleton.

Kawai M, Breggia AC, DeMambro VE, Shen X, Canalis E, Bouxsein ML, Beamer WG, Clemmons DR, Rosen CJ.

J Biol Chem. 2011 Apr 22;286(16):14670-80. doi: 10.1074/jbc.M110.193334. Epub 2011 Mar 3. Erratum in: J Biol Chem. 2011 Dec 16;286(50):43588.

13.

BMD regulation on mouse distal chromosome 1, candidate genes, and response to ovariectomy or dietary fat.

Beamer WG, Shultz KL, Coombs HF 3rd, DeMambro VE, Reinholdt LG, Ackert-Bicknell CL, Canalis E, Rosen CJ, Donahue LR.

J Bone Miner Res. 2011 Jan;26(1):88-99. doi: 10.1002/jbmr.200.

14.

Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice.

Canalis E, Zanotti S, Beamer WG, Economides AN, Smerdel-Ramoya A.

Endocrinology. 2010 Aug;151(8):3490-501. doi: 10.1210/en.2010-0145. Epub 2010 Jun 9.

15.

Quantitative trait loci for tibial bone strength in C57BL/6J and C3H/HeJ inbred strains of mice.

Jiao F, Chiu H, Jiao Y, de Rijk WG, Li X, Eckstein EC, Beamer WG, Gu W.

J Genet. 2010 Apr;89(1):21-7.

16.

A novel spontaneous mutation of Irs1 in mice results in hyperinsulinemia, reduced growth, low bone mass and impaired adipogenesis.

DeMambro VE, Kawai M, Clemens TL, Fulzele K, Maynard JA, Marín de Evsikova C, Johnson KR, Canalis E, Beamer WG, Rosen CJ, Donahue LR.

J Endocrinol. 2010 Mar;204(3):241-53. doi: 10.1677/JOE-09-0328. Epub 2009 Dec 23.

17.

Nephroblastoma overexpressed (Nov) inactivation sensitizes osteoblasts to bone morphogenetic protein-2, but nov is dispensable for skeletal homeostasis.

Canalis E, Smerdel-Ramoya A, Durant D, Economides AN, Beamer WG, Zanotti S.

Endocrinology. 2010 Jan;151(1):221-33. doi: 10.1210/en.2009-0574. Epub 2009 Nov 24.

18.

Gender- and compartment-specific bone loss in C57BL/6J mice: correlation to season?

Delahunty KM, Horton LG, Coombs HF 3rd, Shultz KL, Svenson KL, Marion MA, Holick MF, Beamer WG, Rosen CJ.

J Clin Densitom. 2009 Jan-Mar;12(1):89-94. doi: 10.1016/j.jocd.2008.10.008.

19.

Quantitative trait loci, genes, and polymorphisms that regulate bone mineral density in mouse.

Xiong Q, Jiao Y, Hasty KA, Canale ST, Stuart JM, Beamer WG, Deng HW, Baylink D, Gu W.

Genomics. 2009 May;93(5):401-14. doi: 10.1016/j.ygeno.2008.12.008. Epub 2009 Jan 14. Review.

20.

PPARG by dietary fat interaction influences bone mass in mice and humans.

Ackert-Bicknell CL, Demissie S, Marín de Evsikova C, Hsu YH, DeMambro VE, Karasik D, Cupples LA, Ordovas JM, Tucker KL, Cho K, Canalis E, Paigen B, Churchill GA, Forejt J, Beamer WG, Ferrari S, Bouxsein ML, Kiel DP, Rosen CJ.

J Bone Miner Res. 2008 Sep;23(9):1398-408. doi: 10.1359/jbmr.080419.

21.

A close examination of genes within quantitative trait loci of bone mineral density in whole mouse genome.

Xiong Q, Han C, Beamer WG, Gu W.

Crit Rev Eukaryot Gene Expr. 2008;18(4):323-43. Review.

PMID:
18652562
22.

Quantitative trait loci for BMD in an SM/J by NZB/BlNJ intercross population and identification of Trps1 as a probable candidate gene.

Ishimori N, Stylianou IM, Korstanje R, Marion MA, Li R, Donahue LR, Rosen CJ, Beamer WG, Paigen B, Churchill GA.

J Bone Miner Res. 2008 Sep;23(9):1529-37. doi: 10.1359/jbmr.080414.

23.

Gender-specific changes in bone turnover and skeletal architecture in igfbp-2-null mice.

DeMambro VE, Clemmons DR, Horton LG, Bouxsein ML, Wood TL, Beamer WG, Canalis E, Rosen CJ.

Endocrinology. 2008 May;149(5):2051-61. doi: 10.1210/en.2007-1068. Epub 2008 Feb 14.

24.

Evaluation of gene expression profiling in a mouse model of L-gulonolactone oxidase gene deficiency.

Yan J, Jiao Y, Li X, Jiao F, Beamer WG, Rosen CJ, Gu W.

Genet Mol Biol. 2007;30(2):322-329.

25.
26.

Bone quality and bone strength in BXH recombinant inbred mice.

Ng AH, Wang SX, Turner CH, Beamer WG, Grynpas MD.

Calcif Tissue Int. 2007 Sep;81(3):215-23. Epub 2007 Jul 20.

PMID:
17638038
27.

Genetic regulation of femoral bone mineral density: complexity of sex effect in chromosome 1 revealed by congenic sublines of mice.

Edderkaoui B, Baylink DJ, Beamer WG, Shultz KL, Wergedal JE, Mohan S.

Bone. 2007 Sep;41(3):340-5. Epub 2007 Jun 6.

PMID:
17618849
28.

Quantitative trait loci that determine mouse tibial nanoindentation properties in an F2 population derived from C57BL/6J x C3H/HeJ.

Jiao Y, Chiu H, Fan Z, Jiao F, Eckstein EC, Beamer WG, Gu W.

Calcif Tissue Int. 2007 Jun;80(6):383-90. Epub 2007 Jun 7.

PMID:
17551771
29.

Mapping genetic loci that regulate lipid levels in a NZB/B1NJxRF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains.

Wergedal JE, Ackert-Bicknell CL, Beamer WG, Mohan S, Baylink DJ, Srivastava AK.

J Lipid Res. 2007 Aug;48(8):1724-34. Epub 2007 May 13.

30.

Genetic dissection of mouse distal chromosome 1 reveals three linked BMD QTLs with sex-dependent regulation of bone phenotypes.

Beamer WG, Shultz KL, Ackert-Bicknell CL, Horton LG, Delahunty KM, Coombs HF 3rd, Donahue LR, Canalis E, Rosen CJ.

J Bone Miner Res. 2007 Aug;22(8):1187-96.

31.

Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene.

Edderkaoui B, Baylink DJ, Beamer WG, Wergedal JE, Porte R, Chaudhuri A, Mohan S.

Genome Res. 2007 May;17(5):577-85. Epub 2007 Apr 6.

32.

Genetic effects on bone mechanotransduction in congenic mice harboring bone size and strength quantitative trait loci.

Robling AG, Warden SJ, Shultz KL, Beamer WG, Turner CH.

J Bone Miner Res. 2007 Jul;22(7):984-91.

33.

Detecting novel bone density and bone size quantitative trait loci using a cross of MRL/MpJ and CAST/EiJ inbred mice.

Yu H, Mohan S, Edderkaoui B, Masinde GL, Davidson HM, Wergedal JE, Beamer WG, Baylink DJ.

Calcif Tissue Int. 2007 Feb;80(2):103-10. Epub 2007 Feb 2.

PMID:
17308992
34.

Effects of carbonic anhydrase VIII deficiency on cerebellar gene expression profiles in the wdl mouse.

Yan J, Jiao Y, Jiao F, Stuart J, Donahue LR, Beamer WG, Li X, Roe BA, LeDoux MS, Gu W.

Neurosci Lett. 2007 Feb 21;413(3):196-201. Epub 2006 Dec 15.

35.

Early apoptotic responses in transgenic mouse mammary carcinoma for photodynamic therapy.

Walt H, Nap M, Dorward AM, Leers MP, Tennent BJ, Varga Z, Stallmach T, Björklund V, Beamer WG.

Photodiagnosis Photodyn Ther. 2006 Dec;3(4):227-33. doi: 10.1016/j.pdpdt.2006.07.002. Epub 2006 Sep 15.

PMID:
25046987
36.

Femur mechanical properties in the F2 progeny of an NZB/B1NJ x RF/J cross are regulated predominantly by genetic loci that regulate bone geometry.

Wergedal JE, Ackert-Bicknell CL, Tsaih SW, Sheng MH, Li R, Mohan S, Beamer WG, Churchill GA, Baylink DJ.

J Bone Miner Res. 2006 Aug;21(8):1256-66.

37.

Congenic mice provide in vivo evidence for a genetic locus that modulates serum insulin-like growth factor-I and bone acquisition.

Delahunty KM, Shultz KL, Gronowicz GA, Koczon-Jaremko B, Adamo ML, Horton LG, Lorenzo J, Donahue LR, Ackert-Bicknell C, Kream BE, Beamer WG, Rosen CJ.

Endocrinology. 2006 Aug;147(8):3915-23. Epub 2006 May 4.

PMID:
16675518
38.

Genetic increase in serum insulin-like growth factor-I (IGF-I) in C3H/HeJ compared with C57BL/6J mice is associated with increased transcription from the IGF-I exon 2 promoter.

Adamo ML, Ma X, Ackert-Bicknell CL, Donahue LR, Beamer WG, Rosen CJ.

Endocrinology. 2006 Jun;147(6):2944-55. Epub 2006 Mar 9.

PMID:
16527837
39.

IGF-I secretion by prostate carcinoma cells does not alter tumor-bone cell interactions in vitro or in vivo.

Rubin J, Fan X, Rahnert J, Sen B, Hsieh CL, Murphy TC, Nanes MS, Horton LG, Beamer WG, Rosen CJ.

Prostate. 2006 Jun 1;66(8):789-800.

PMID:
16482567
40.

Quantitative trait loci that determine BMD in C57BL/6J and 129S1/SvImJ inbred mice.

Ishimori N, Li R, Walsh KA, Korstanje R, Rollins JA, Petkov P, Pletcher MT, Wiltshire T, Donahue LR, Rosen CJ, Beamer WG, Churchill GA, Paigen B.

J Bone Miner Res. 2006 Jan;21(1):105-12. Epub 2005 Sep 9.

41.

Multiple genetic loci from CAST/EiJ chromosome 1 affect vBMD either positively or negatively in a C57BL/6J background.

Edderkaoui B, Baylink DJ, Beamer WG, Wergedal JE, Dunn NR, Shultz KL, Mohan S.

J Bone Miner Res. 2006 Jan;21(1):97-104. Epub 2005 Oct 17.

42.

Chromosomal inversion discovered in C3H/HeJ mice.

Akeson EC, Donahue LR, Beamer WG, Shultz KL, Ackert-Bicknell C, Rosen CJ, Corrigan J, Davisson MT.

Genomics. 2006 Feb;87(2):311-3. Epub 2005 Nov 23.

43.
44.

Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3h/HeJ inbred strains of mice. (2001).

Beamer WG, Shultz KL, Donahue LR, Churchill GA, Sen S, Wergedal JR, Baylink DJ, Rosen CJ.

J Bone Miner Res. 2005 Sep;20(9):1701-12; discussion 1700. No abstract available.

45.

Carbonic anhydrase-related protein VIII deficiency is associated with a distinctive lifelong gait disorder in waddles mice.

Jiao Y, Yan J, Zhao Y, Donahue LR, Beamer WG, Li X, Roe BA, Ledoux MS, Gu W.

Genetics. 2005 Nov;171(3):1239-46. Epub 2005 Aug 22.

46.

Effects of growth hormone transgene expression on vertebrae in a mouse model of osteogenesis imperfecta.

King D, Chase J, Havey RM, Voronov L, Sartori M, McEwen HA, Beamer WG, Patwardhan AG.

Spine (Phila Pa 1976). 2005 Jul 1;30(13):1491-5.

PMID:
15990661
47.

Ovariectomy-induced bone loss varies among inbred strains of mice.

Bouxsein ML, Myers KS, Shultz KL, Donahue LR, Rosen CJ, Beamer WG.

J Bone Miner Res. 2005 Jul;20(7):1085-92. Epub 2005 Mar 7.

48.

Is skeletal mechanotransduction under genetic control?

Turner CH, Beamer WG.

J Musculoskelet Neuronal Interact. 2002 Mar;2(3):237-8.

49.

Genetics and bone. Using the mouse to understand man.

Beamer WG, Donahue LR, Rosen CJ.

J Musculoskelet Neuronal Interact. 2002 Mar;2(3):225-31.

50.

Distal Chr 4 harbors a genetic locus (Gct1) fundamental for spontaneous ovarian granulosa cell tumorigenesis in a mouse model.

Dorward AM, Shultz KL, Horton LG, Li R, Churchill GA, Beamer WG.

Cancer Res. 2005 Feb 15;65(4):1259-64.

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