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An immunocompetent rat model of infection with Cryptosporidium species: Cryptosporidium hominis and Cryptosporidium parvum.

Dayao DA, Sheoran A, Carvalho A, Xu H, Beamer G, Widmer G, Tzipori S.

Int J Parasitol. 2019 Nov 21. pii: S0020-7519(19)30268-1. doi: 10.1016/j.ijpara.2019.10.002. [Epub ahead of print]


The impact of Actotoxumab treatment of gnotobiotic piglets infected with different Clostridium difficile isogenic mutants.

Danz HR, Lee S, Chapman-Bonofiglio SP, Ginese M, Beamer G, Girouard DJ, Tzipori S.

J Infect Dis. 2019 Sep 9. pii: jiz459. doi: 10.1093/infdis/jiz459. [Epub ahead of print]


The Lung Mucosa Environment in the Elderly Increases Host Susceptibility to Mycobacterium tuberculosis Infection.

Moliva JI, Duncan MA, Olmo-Fontánez A, Akhter A, Arnett E, Scordo JM, Ault R, Sasindran SJ, Azad AK, Montoya MJ, Reinhold-Larsson N, Rajaram MVS, Merrit RE, Lafuse WP, Zhang L, Wang SH, Beamer G, Wang Y, Proud K, Maselli DJ, Peters J, Weintraub ST, Turner J, Schlesinger LS, Torrelles JB.

J Infect Dis. 2019 Jul 2;220(3):514-523. doi: 10.1093/infdis/jiz138.


Piperazine-Derivative MMV665917: An Effective Drug in the Diarrheic Piglet Model of Cryptosporidium hominis.

Lee S, Ginese M, Girouard D, Beamer G, Huston CD, Osbourn D, Griggs DW, Tzipori S.

J Infect Dis. 2019 Jun 19;220(2):285-293. doi: 10.1093/infdis/jiz105.


Selective delipidation of Mycobacterium bovis BCG enables direct pulmonary vaccination and enhances protection against Mycobacterium tuberculosis.

Moliva JI, Hossfeld AP, Sidiki S, Canan CH, Dwivedi V, Beamer G, Turner J, Torrelles JB.

Mucosal Immunol. 2019 May;12(3):805-815. doi: 10.1038/s41385-019-0148-2. Epub 2019 Feb 18.


The piglet acute diarrhea model for evaluating efficacy of treatment and control of cryptosporidiosis.

Lee S, Beamer G, Tzipori S.

Hum Vaccin Immunother. 2019;15(6):1445-1452. doi: 10.1080/21645515.2018.1498436. Epub 2018 Aug 27.


Therapeutic Efficacy of Bumped Kinase Inhibitor 1369 in a Pig Model of Acute Diarrhea Caused by Cryptosporidium hominis.

Lee S, Ginese M, Beamer G, Danz HR, Girouard DJ, Chapman-Bonofiglio SP, Lee M, Hulverson MA, Choi R, Whitman GR, Ojo KK, Arnold SLM, Van Voorhis WC, Tzipori S.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e00147-18. doi: 10.1128/AAC.00147-18. Print 2018 Jul.


The therapeutic efficacy of azithromycin and nitazoxanide in the acute pig model of Cryptosporidium hominis.

Lee S, Harwood M, Girouard D, Meyers MJ, Campbell MA, Beamer G, Tzipori S.

PLoS One. 2017 Oct 3;12(10):e0185906. doi: 10.1371/journal.pone.0185906. eCollection 2017.


Exposure to human alveolar lining fluid enhances Mycobacterium bovis BCG vaccine efficacy against Mycobacterium tuberculosis infection in a CD8+ T-cell-dependent manner.

Moliva JI, Hossfeld AP, Canan CH, Dwivedi V, Wewers MD, Beamer G, Turner J, Torrelles JB.

Mucosal Immunol. 2018 May;11(3):968-978. doi: 10.1038/mi.2017.80. Epub 2017 Sep 20.


Transgenerational Social Stress Alters Immune-Behavior Associations and the Response to Vaccination.

Hicks-Nelson A, Beamer G, Gurel K, Cooper R, Nephew BC.

Brain Sci. 2017 Jul 21;7(7). pii: E89. doi: 10.3390/brainsci7070089.


Dorsally located corneal dermoid in a cat.

LoPinto AJ, Pirie CG, Huynh T, Beamer G.

JFMS Open Rep. 2016 Apr 7;2(1):2055116916641970. doi: 10.1177/2055116916641970. eCollection 2016 Jan-Jun.


Effects of Chronic Social Stress and Maternal Intranasal Oxytocin and Vasopressin on Offspring Interferon-γ and Behavior.

Murgatroyd CA, Hicks-Nelson A, Fink A, Beamer G, Gurel K, Elnady F, Pittet F, Nephew BC.

Front Endocrinol (Lausanne). 2016 Dec 14;7:155. doi: 10.3389/fendo.2016.00155. eCollection 2016.


IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection.

Booty MG, Barreira-Silva P, Carpenter SM, Nunes-Alves C, Jacques MK, Stowell BL, Jayaraman P, Beamer G, Behar SM.

Sci Rep. 2016 Nov 7;6:36720. doi: 10.1038/srep36720.


Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype.

Smith CM, Proulx MK, Olive AJ, Laddy D, Mishra BB, Moss C, Gutierrez NM, Bellerose MM, Barreira-Silva P, Phuah JY, Baker RE, Behar SM, Kornfeld H, Evans TG, Beamer G, Sassetti CM.

MBio. 2016 Sep 20;7(5). pii: e01516-16. doi: 10.1128/mBio.01516-16.


A Tetraspecific VHH-Based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection.

Schmidt DJ, Beamer G, Tremblay JM, Steele JA, Kim HB, Wang Y, Debatis M, Sun X, Kashentseva EA, Dmitriev IP, Curiel DT, Shoemaker CB, Tzipori S.

Clin Vaccine Immunol. 2016 Sep 6;23(9):774-84. doi: 10.1128/CVI.00730-15. Print 2016 Sep.


Glaucoma with Descemet's membrane detachment in five horses.

Henriksen ML, La Croix N, Wilkie DA, Lassaline-Utter M, Brantman KR, Beamer GL, Teixeira LBC, Dubielzig RR.

Vet Ophthalmol. 2017 May;20(3):273-279. doi: 10.1111/vop.12388. Epub 2016 May 18.


Acute Exposure to Crystalline Silica Reduces Macrophage Activation in Response to Bacterial Lipoproteins.

Beamer GL, Seaver BP, Jessop F, Shepherd DM, Beamer CA.

Front Immunol. 2016 Feb 15;7:49. doi: 10.3389/fimmu.2016.00049. eCollection 2016.


Immunogenicity in dogs and protection against visceral leishmaniasis induced by a 14kDa Leishmania infantum recombinant polypeptide.

Abeijon C, Daifalla N, Krautz-Peterson G, Pizzirani S, Beamer G, Frazatti-Gallina NM, Raw I, Campos-Neto A.

Trials Vaccinol. 2016;5:1-7.


Mouse models of human TB pathology: roles in the analysis of necrosis and the development of host-directed therapies.

Kramnik I, Beamer G.

Semin Immunopathol. 2016 Mar;38(2):221-37. doi: 10.1007/s00281-015-0538-9. Epub 2015 Nov 5. Review.


Microscopic Lesions in Canine Eyes with Primary Glaucoma.

Beamer G, Reilly CM, Pizzirani S.

Vet Clin North Am Small Anim Pract. 2015 Nov;45(6):1213-33, vi. doi: 10.1016/j.cvsm.2015.07.001. Review.


Lung necrosis and neutrophils reflect common pathways of susceptibility to Mycobacterium tuberculosis in genetically diverse, immune-competent mice.

Niazi MK, Dhulekar N, Schmidt D, Major S, Cooper R, Abeijon C, Gatti DM, Kramnik I, Yener B, Gurcan M, Beamer G.

Dis Model Mech. 2015 Sep;8(9):1141-53. doi: 10.1242/dmm.020867. Epub 2015 Jul 23.


Genetically diverse mice are novel and valuable models of age-associated susceptibility to Mycobacterium tuberculosis.

Harrison DE, Astle CM, Niazi MKK, Major S, Beamer GL.

Immun Ageing. 2014 Dec 16;11(1):24. doi: 10.1186/s12979-014-0024-6. eCollection 2014.


Unilateral choristoma of the nictitating membrane in a horse.

Gornik KR, Pirie CG, Beamer GL.

J Am Vet Med Assoc. 2015 Jan 15;246(2):231-5. doi: 10.2460/javma.246.2.231.


Bone marrow mesenchymal stem cells provide an antibiotic-protective niche for persistent viable Mycobacterium tuberculosis that survive antibiotic treatment.

Beamer G, Major S, Das B, Campos-Neto A.

Am J Pathol. 2014 Dec;184(12):3170-5. doi: 10.1016/j.ajpath.2014.08.024. Epub 2014 Oct 16.


Rapid prototyped sutureless anastomosis device from self-curing silk bio-ink.

Jose RR, Raja WK, Ibrahim AM, Koolen PG, Kim K, Abdurrob A, Kluge JA, Lin SJ, Beamer G, Kaplan DL.

J Biomed Mater Res B Appl Biomater. 2015 Oct;103(7):1333-43. doi: 10.1002/jbm.b.33312. Epub 2014 Nov 11.


Hyperimmune bovine colostrum as a novel therapy to combat Clostridium difficile infection.

Sponseller JK, Steele JA, Schmidt DJ, Kim HB, Beamer G, Sun X, Tzipori S.

J Infect Dis. 2015 Apr 15;211(8):1334-41. doi: 10.1093/infdis/jiu605. Epub 2014 Nov 7.


Adenovirus vector expressing Stx1/Stx2-neutralizing agent protects piglets infected with Escherichia coli O157:H7 against fatal systemic intoxication.

Sheoran AS, Dmitriev IP, Kashentseva EA, Cohen O, Mukherjee J, Debatis M, Shearer J, Tremblay JM, Beamer G, Curiel DT, Shoemaker CB, Tzipori S.

Infect Immun. 2015 Jan;83(1):286-91. doi: 10.1128/IAI.02360-14. Epub 2014 Nov 3.


Systemically administered IgG anti-toxin antibodies protect the colonic mucosa during infection with Clostridium difficile in the piglet model.

Cohen OR, Steele JA, Zhang Q, Schmidt DJ, Wang Y, Hamel PE, Beamer G, Xu B, Tzipori S.

PLoS One. 2014 Oct 27;9(10):e111075. doi: 10.1371/journal.pone.0111075. eCollection 2014.


Beneficial effect of oral tigecycline treatment on Clostridium difficile infection in gnotobiotic piglets.

Kim HB, Zhang Q, Sun X, Beamer G, Wang Y, Tzipori S.

Antimicrob Agents Chemother. 2014 Dec;58(12):7560-4. doi: 10.1128/AAC.03447-14. Epub 2014 Sep 29.


Prolonged prophylactic protection from botulism with a single adenovirus treatment promoting serum expression of a VHH-based antitoxin protein.

Mukherjee J, Dmitriev I, Debatis M, Tremblay JM, Beamer G, Kashentseva EA, Curiel DT, Shoemaker CB.

PLoS One. 2014 Aug 29;9(8):e106422. doi: 10.1371/journal.pone.0106422. eCollection 2014.


Detecting and characterizing cellular responses to Mycobacterium tuberculosis from histology slides.

Niazi MK, Beamer G, Gurcan MN.

Cytometry A. 2014 Feb;85(2):151-61. doi: 10.1002/cyto.a.22424. Epub 2013 Dec 12.


Corneal sequestrum in a dog with chronic unilateral keratoconjunctivitis sicca.

Dubin AJ, Pizzirani S, Beamer GL.

J Am Vet Med Assoc. 2013 Dec 15;243(12):1751-5. doi: 10.2460/javma.243.12.1751.


A single VHH-based toxin-neutralizing agent and an effector antibody protect mice against challenge with Shiga toxins 1 and 2.

Tremblay JM, Mukherjee J, Leysath CE, Debatis M, Ofori K, Baldwin K, Boucher C, Peters R, Beamer G, Sheoran A, Bedenice D, Tzipori S, Shoemaker CB.

Infect Immun. 2013 Dec;81(12):4592-603. doi: 10.1128/IAI.01033-13. Epub 2013 Sep 30.


MBX-500 is effective for treatment of Clostridium difficile infection in gnotobiotic piglets.

Steele J, Zhang Q, Beamer G, Butler M, Bowlin T, Tzipori S.

Antimicrob Agents Chemother. 2013 Aug;57(8):4039-41. doi: 10.1128/AAC.00304-13. Epub 2013 May 20.


Tuberculosis in CBA/J mice.

Major S, Turner J, Beamer G.

Vet Pathol. 2013 Nov;50(6):1016-21. doi: 10.1177/0300985813482952. Epub 2013 Mar 26.


Clonal expansions of CD8+ T cells with IL-10 secreting capacity occur during chronic Mycobacterium tuberculosis infection.

Cyktor JC, Carruthers B, Beamer GL, Turner J.

PLoS One. 2013;8(3):e58612. doi: 10.1371/journal.pone.0058612. Epub 2013 Mar 5.


IL-10 inhibits mature fibrotic granuloma formation during Mycobacterium tuberculosis infection.

Cyktor JC, Carruthers B, Kominsky RA, Beamer GL, Stromberg P, Turner J.

J Immunol. 2013 Mar 15;190(6):2778-90. doi: 10.4049/jimmunol.1202722. Epub 2013 Feb 8.


CBA/J mice generate protective immunity to soluble Ag85 but fail to respond efficiently to Ag85 during natural Mycobacterium tuberculosis infection.

Beamer GL, Cyktor J, Flaherty DK, Stromberg PC, Carruthers B, Turner J.

Eur J Immunol. 2012 Apr;42(4):870-9. doi: 10.1002/eji.201142054.


A novel spongiform leukoencephalomyelopathy in Border Terrier puppies.

Martin-Vaquero P, da Costa RC, Simmons JK, Beamer GL, Jäderlund KH, Oglesbee MJ.

J Vet Intern Med. 2012 Mar-Apr;26(2):402-6. doi: 10.1111/j.1939-1676.2011.00873.x. Epub 2012 Jan 23. No abstract available.


H-2 alleles contribute to antigen 85-specific interferon-gamma responses during Mycobacterium tuberculosis infection.

Beamer GL, Cyktor J, Carruthers B, Turner J.

Cell Immunol. 2011;271(1):53-61. doi: 10.1016/j.cellimm.2011.06.002. Epub 2011 Jun 12.


CCL5 participates in early protection against Mycobacterium tuberculosis.

Vesosky B, Rottinghaus EK, Stromberg P, Turner J, Beamer G.

J Leukoc Biol. 2010 Jun;87(6):1153-65. doi: 10.1189/jlb.1109742. Epub 2010 Apr 6.


Adjuvant CCNU (lomustine) and prednisone chemotherapy for dogs with incompletely excised grade 2 mast cell tumors.

Hosoya K, Kisseberth WC, Alvarez FJ, Lara-Garcia A, Beamer G, Stromberg PC, Couto CG.

J Am Anim Hosp Assoc. 2009 Jan-Feb;45(1):14-8.


Interleukin-10 promotes Mycobacterium tuberculosis disease progression in CBA/J mice.

Beamer GL, Flaherty DK, Assogba BD, Stromberg P, Gonzalez-Juarrero M, de Waal Malefyt R, Vesosky B, Turner J.

J Immunol. 2008 Oct 15;181(8):5545-50.


Hematuria and transitional cell papilloma of the renal pelvis treated via unilateral nephrectomy in an alpaca.

Gerspach C, Hull BL, Rings DM, Chew DJ, Beamer GL, Hubbell JA, Lakritz J.

J Am Vet Med Assoc. 2008 Apr 15;232(8):1206-9. doi: 10.2460/javma.232.8.1206.


Peripheral blood gamma interferon release assays predict lung responses and Mycobacterium tuberculosis disease outcome in mice.

Beamer GL, Flaherty DK, Vesosky B, Turner J.

Clin Vaccine Immunol. 2008 Mar;15(3):474-83. doi: 10.1128/CVI.00408-07. Epub 2008 Jan 9.


Exposure to Mycobacterium avium can modulate established immunity against Mycobacterium tuberculosis infection generated by Mycobacterium bovis BCG vaccination.

Flaherty DK, Vesosky B, Beamer GL, Stromberg P, Turner J.

J Leukoc Biol. 2006 Dec;80(6):1262-71. Epub 2006 Sep 12.


Murine models of susceptibility to tuberculosis.

Beamer GL, Turner J.

Arch Immunol Ther Exp (Warsz). 2005 Nov-Dec;53(6):469-83. Review.


State health care reform politics and the unfortunate end of the 1990s.

Beamer G.

J Health Polit Policy Law. 2004 Apr;29(2):293-304. No abstract available.


Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice.

Christianson SW, Greiner DL, Schweitzer IB, Gott B, Beamer GL, Schweitzer PA, Hesselton RM, Shultz LD.

Cell Immunol. 1996 Aug 1;171(2):186-99.


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