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Items: 1 to 50 of 101

1.

Burkholderia pseudomallei Rapidly Infects the Brain Stem and Spinal Cord via the Trigeminal Nerve after Intranasal Inoculation.

St John JA, Walkden H, Nazareth L, Beagley KW, Ulett GC, Batzloff MR, Beacham IR, Ekberg JA.

Infect Immun. 2016 Aug 19;84(9):2681-8. doi: 10.1128/IAI.00361-16. Print 2016 Sep.

2.

Burkholderia pseudomallei Capsule Exacerbates Respiratory Melioidosis but Does Not Afford Protection against Antimicrobial Signaling or Bacterial Killing in Human Olfactory Ensheathing Cells.

Dando SJ, Ipe DS, Batzloff M, Sullivan MJ, Crossman DK, Crowley M, Strong E, Kyan S, Leclercq SY, Ekberg JAK, St John J, Beacham IR, Ulett GC.

Infect Immun. 2016 Jun 23;84(7):1941-1956. doi: 10.1128/IAI.01546-15. Print 2016 Jul.

3.

Functional and structural characterization of a heparanase.

Bohlmann L, Tredwell GD, Yu X, Chang CW, Haselhorst T, Winger M, Dyason JC, Thomson RJ, Tiralongo J, Beacham IR, Blanchard H, von Itzstein M.

Nat Chem Biol. 2015 Dec;11(12):955-7. doi: 10.1038/nchembio.1956. Epub 2015 Nov 2.

PMID:
26565989
4.

Pathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasion.

Dando SJ, Mackay-Sim A, Norton R, Currie BJ, St John JA, Ekberg JA, Batzloff M, Ulett GC, Beacham IR.

Clin Microbiol Rev. 2014 Oct;27(4):691-726. doi: 10.1128/CMR.00118-13. Review.

5.

Burkholderia pseudomallei penetrates the brain via destruction of the olfactory and trigeminal nerves: implications for the pathogenesis of neurological melioidosis.

St John JA, Ekberg JA, Dando SJ, Meedeniya AC, Horton RE, Batzloff M, Owen SJ, Holt S, Peak IR, Ulett GC, Mackay-Sim A, Beacham IR.

MBio. 2014 Apr 15;5(2):e00025. doi: 10.1128/mBio.00025-14.

6.

Distinct physiological roles for the two L-asparaginase isozymes of Escherichia coli.

Srikhanta YN, Atack JM, Beacham IR, Jennings MP.

Biochem Biophys Res Commun. 2013 Jul 5;436(3):362-5. doi: 10.1016/j.bbrc.2013.05.066. Epub 2013 May 31.

PMID:
23726917
7.

Quorum sensing negatively regulates multinucleate cell formation during intracellular growth of Burkholderia pseudomallei in macrophage-like cells.

Horton RE, Grant GD, Matthews B, Batzloff M, Owen SJ, Kyan S, Flegg CP, Clark AM, Ulett GC, Morrison N, Peak IR, Beacham IR.

PLoS One. 2013 May 21;8(5):e63394. doi: 10.1371/journal.pone.0063394. Print 2013.

8.

Interaction of Burkholderia pseudomallei and Burkholderia thailandensis with human monocyte-derived dendritic cells.

Horton RE, Morrison NA, Beacham IR, Peak IR.

J Med Microbiol. 2012 May;61(Pt 5):607-14. doi: 10.1099/jmm.0.038588-0. Epub 2012 Feb 2.

PMID:
22301613
9.

Coupling between codon usage, translation and protein export in Escherichia coli.

Zalucki YM, Beacham IR, Jennings MP.

Biotechnol J. 2011 Jun;6(6):660-7. doi: 10.1002/biot.201000334. Epub 2011 May 13. Review.

PMID:
21567959
10.

Nasal-associated lymphoid tissue and olfactory epithelium as portals of entry for Burkholderia pseudomallei in murine melioidosis.

Owen SJ, Batzloff M, Chehrehasa F, Meedeniya A, Casart Y, Logue CA, Hirst RG, Peak IR, Mackay-Sim A, Beacham IR.

J Infect Dis. 2009 Jun 15;199(12):1761-70. doi: 10.1086/599210.

PMID:
19456230
11.

Biased codon usage in signal peptides: a role in protein export.

Zalucki YM, Beacham IR, Jennings MP.

Trends Microbiol. 2009 Apr;17(4):146-50. doi: 10.1016/j.tim.2009.01.005. Epub 2009 Mar 21.

PMID:
19307122
12.

Facile construction of unmarked deletion mutants in Burkholderia pseudomallei using sacB counter-selection in sucrose-resistant and sucrose-sensitive isolates.

Logue CA, Peak IR, Beacham IR.

J Microbiol Methods. 2009 Mar;76(3):320-3. doi: 10.1016/j.mimet.2008.12.007. Epub 2008 Dec 29.

PMID:
19150470
13.

Evaluation of recombinant antigens for diagnosis of melioidosis.

Allwood EM, Logue CA, Hafner GJ, Ketheesan N, Norton RE, Peak IR, Beacham IR.

FEMS Immunol Med Microbiol. 2008 Oct;54(1):144-53. doi: 10.1111/j.1574-695X.2008.00464.x. Epub 2008 Jul 24.

14.

Genetic tools for select-agent-compliant manipulation of Burkholderia pseudomallei.

Choi KH, Mima T, Casart Y, Rholl D, Kumar A, Beacham IR, Schweizer HP.

Appl Environ Microbiol. 2008 Feb;74(4):1064-75. Epub 2007 Dec 21. Erratum in: Appl Environ Microbiol. 2008 Aug;74(16):5265.

15.

The bacterial gene lfpA influences the potent induction of calcitonin receptor and osteoclast-related genes in Burkholderia pseudomallei-induced TRAP-positive multinucleated giant cells.

Boddey JA, Day CJ, Flegg CP, Ulrich RL, Stephens SR, Beacham IR, Morrison NA, Peak IR.

Cell Microbiol. 2007 Feb;9(2):514-31. Epub 2006 Sep 20.

PMID:
16987331
16.
17.

A type IV pilin, PilA, Contributes To Adherence of Burkholderia pseudomallei and virulence in vivo.

Essex-Lopresti AE, Boddey JA, Thomas R, Smith MP, Hartley MG, Atkins T, Brown NF, Tsang CH, Peak IR, Hill J, Beacham IR, Titball RW.

Infect Immun. 2005 Feb;73(2):1260-4.

19.

Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei.

Holden MT, Titball RW, Peacock SJ, Cerdeño-Tárraga AM, Atkins T, Crossman LC, Pitt T, Churcher C, Mungall K, Bentley SD, Sebaihia M, Thomson NR, Bason N, Beacham IR, Brooks K, Brown KA, Brown NF, Challis GL, Cherevach I, Chillingworth T, Cronin A, Crossett B, Davis P, DeShazer D, Feltwell T, Fraser A, Hance Z, Hauser H, Holroyd S, Jagels K, Keith KE, Maddison M, Moule S, Price C, Quail MA, Rabbinowitsch E, Rutherford K, Sanders M, Simmonds M, Songsivilai S, Stevens K, Tumapa S, Vesaratchavest M, Whitehead S, Yeats C, Barrell BG, Oyston PC, Parkhill J.

Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14240-5. Epub 2004 Sep 17.

20.

Whole genome analysis reveals a high incidence of non-optimal codons in secretory signal sequences of Escherichia coli.

Power PM, Jones RA, Beacham IR, Bucholtz C, Jennings MP.

Biochem Biophys Res Commun. 2004 Sep 24;322(3):1038-44.

PMID:
15336569
21.

Identification of a novel two-partner secretion system from Burkholderia pseudomallei.

Brown NF, Logue CA, Boddey JA, Scott R, Hirst RG, Beacham IR.

Mol Genet Genomics. 2004 Sep;272(2):204-15. Epub 2004 Aug 13.

PMID:
15316770
22.

Searching for virulence Burkholderia pseudomallei genes by immunoscreening the lambda ZAPII expressed genomic library.

Jitsurong S, Chirathaworn C, Brown NF, Beacham IR, Tumwasorn S.

Southeast Asian J Trop Med Public Health. 2003 Dec;34(4):810-21.

PMID:
15115093
23.
25.
26.
27.

The cryptic ushA gene (ushA(c)) in natural isolates of Salmonella enterica (serotype Typhimurium) has been inactivated by a single missense mutation.

Innes D, Beacham IR, Beven CA, Douglas M, Laird MW, Joly JC, Burns DM.

Microbiology. 2001 Jul;147(Pt 7):1887-96.

PMID:
11429465
28.
29.

The aprX-lipA operon of Pseudomonas fluorescens B52: a molecular analysis of metalloprotease and lipase production.

Woods RG, Burger M, Beven CA, Beacham IR.

Microbiology. 2001 Feb;147(Pt 2):345-54.

PMID:
11158351
30.

Temperature regulation of protease in Pseudomonas fluorescens LS107d2 by an ECF sigma factor and a transmembrane activator.

Burger M, Woods RG, McCarthy C, Beacham IR.

Microbiology. 2000 Dec;146 Pt 12:3149-55.

PMID:
11101673
31.
32.
33.
34.

Amylase and 16S rRNA genes from a hyperthermophilic archaebacterium.

Jones RA, Jermiin LS, Easteal S, Patel BK, Beacham IR.

J Appl Microbiol. 1999 Jan;86(1):93-107.

35.
36.
38.

Human stomach class IV alcohol dehydrogenase: molecular genetic analysis.

Cheung B, Anderson JK, Holmes RS, Beacham IR.

Alcohol Clin Exp Res. 1995 Feb;19(1):185-6.

PMID:
7771649
39.

Cloning and molecular analysis of the Salmonella enterica ansP gene, encoding an L-asparagine permease.

Jennings MP, Anderson JK, Beacham IR.

Microbiology. 1995 Jan;141 ( Pt 1):141-6.

PMID:
7894705
40.
41.

Membrane localisation of a UDP-sugar hydrolase, in Salmonella, is by an uncleaved N-terminal signal peptide.

Jones RA, Burns DM, Carruthers DJ, Beacham IR.

FEMS Microbiol Lett. 1993 Dec 15;114(3):299-304.

PMID:
8288107
43.

Regulation of the ansB gene of Salmonella enterica.

Jennings MP, Scott SP, Beacham IR.

Mol Microbiol. 1993 Jul;9(1):165-72.

PMID:
8412661
44.
45.

Bovine corneal aldehyde dehydrogenases: evidence for multiple gene products (ALDH3 and ALDHX).

Algar EM, Cheung B, Hayes J, Holmes RS, Beacham IR.

Adv Exp Med Biol. 1993;328:153-7. No abstract available.

PMID:
8493893
46.

Site-specific mutagenesis of Escherichia coli asparaginase II. None of the three histidine residues is required for catalysis.

Wehner A, Harms E, Jennings MP, Beacham IR, Derst C, Bast P, Röhm KH.

Eur J Biochem. 1992 Sep 1;208(2):475-80.

47.
48.

Molecular analysis of an esterase-encoding gene from a lipolytic psychrotrophic pseudomonad.

McKay DB, Jennings MP, Godfrey EA, MacRae IC, Rogers PJ, Beacham IR.

J Gen Microbiol. 1992 Apr;138(4):701-8.

PMID:
1339464
49.

Hypoxanthine-guanine phosphoribosyltransferase deficiency: analysis of HPRT mutations by direct sequencing and allele-specific amplification.

Sculley DG, Dawson PA, Beacham IR, Emmerson BT, Gordon RB.

Hum Genet. 1991 Oct;87(6):688-92.

PMID:
1937471

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