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Items: 21

1.

Neuroprotective effects and mechanism of cognitive-enhancing choline analogs JWB 1-84-1 and JAY 2-22-33 in neuronal culture and Caenorhabditis elegans.

Keowkase R, Aboukhatwa M, Adam BL, Beach JW, Terry AV Jr, Buccafussco JJ, Luo Y.

Mol Neurodegener. 2010 Dec 16;5:59. doi: 10.1186/1750-1326-5-59.

2.

Transdermal permeation of novel n-acetyl-glucosamine/NSAIDs mutual prodrugs.

Israel B, Garner ST, Thakare M, Elder D, Abney T, Azadi P, Beach JW, Price JC, Ahmed H, Capomacchia AC.

Pharm Dev Technol. 2012 Jan-Feb;17(1):48-54. doi: 10.3109/10837450.2010.513987. Epub 2010 Sep 21.

PMID:
20858066
3.

Desensitization of nicotinic acetylcholine receptors as a strategy for drug development.

Buccafusco JJ, Beach JW, Terry AV Jr.

J Pharmacol Exp Ther. 2009 Feb;328(2):364-70. doi: 10.1124/jpet.108.145292. Epub 2008 Nov 20. Review.

4.

Solubility of (+/-)-ibuprofen and S (+)-ibuprofen in the presence of cosolvents and cyclodextrins.

Nerurkar J, Beach JW, Park MO, Jun HW.

Pharm Dev Technol. 2005;10(3):413-21.

PMID:
16176022
5.

Novel analogs of choline as potential neuroprotective agents.

Buccafusco JJ, Beach JW, Terry AV Jr, Doad GS, Sood A, Arias E, Misawa H, Masai M, Fujii T, Kawashima K.

J Alzheimers Dis. 2004 Dec;6(6 Suppl):S85-92.

PMID:
15665419
6.

Dopamine transporter-mediated cytotoxicity of beta-carbolinium derivatives related to Parkinson's disease: relationship to transporter-dependent uptake.

Storch A, Hwang YI, Gearhart DA, Beach JW, Neafsey EJ, Collins MA, Schwarz J.

J Neurochem. 2004 May;89(3):685-94.

7.

Solubility of guaifenesin in the presence of common pharmaceutical additives.

Mani N, Jun HW, Beach JW, Nerurkar J.

Pharm Dev Technol. 2003;8(4):385-96.

PMID:
14601963
8.

Relative levels of cytoprotection produced by analogs of choline and the role of alpha7-nicotinic acetylcholine receptors.

Jonnala RR, Graham JH 3rd, Terry AV Jr, Beach JW, Young JA, Buccafusco JJ.

Synapse. 2003 Mar 15;47(4):262-9.

PMID:
12539199
9.

Chiral separation of lobeline analogs using high performance capillary electrophoresis and derivatized cyclodextrins as chiral additives.

McCurdy CR, Venkateshwaran TG, Beach JW, Stewart JT.

Electrophoresis. 1999 Jan;20(1):212-8.

PMID:
10065979
10.

Inhibition of brain choline uptake by isoarecolone and lobeline derivatives: implications for potential vector-mediated brain drug delivery.

Metting TL, Burgio DE, Terry AV Jr, Beach JW, McCurdy CR, Allen DD.

Neurosci Lett. 1998 Dec 11;258(1):25-8.

PMID:
9876043
11.

Lobeline and structurally simplified analogs exhibit differential agonist activity and sensitivity to antagonist blockade when compared to nicotine.

Terry AV Jr, Williamson R, Gattu M, Beach JW, McCurdy CR, Sparks JA, Pauly JR.

Neuropharmacology. 1998;37(1):93-102.

PMID:
9680262
13.

Structure-activity relationships of beta-D-(2S,5R)- and alpha-D-(2S,5S)-1,3-oxathiolanyl nucleosides as potential anti-HIV agents.

Jeong LS, Schinazi RF, Beach JW, Kim HO, Shanmuganathan K, Nampalli S, Chun MW, Chung WK, Choi BG, Chu CK.

J Med Chem. 1993 Sep 3;36(18):2627-38.

PMID:
8410975
14.

L-beta-(2S,4S)- and L-alpha-(2S,4R)-dioxolanyl nucleosides as potential anti-HIV agents: asymmetric synthesis and structure-activity relationships.

Kim HO, Schinazi RF, Shanmuganathan K, Jeong LS, Beach JW, Nampalli S, Cannon DL, Chu CK.

J Med Chem. 1993 Mar 5;36(5):519-28.

PMID:
8496934
15.

Asymmetric synthesis and biological evaluation of beta-L-(2R,5S)- and alpha-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential anti-HIV agents.

Jeong LS, Schinazi RF, Beach JW, Kim HO, Nampalli S, Shanmuganathan K, Alves AJ, McMillan A, Chu CK, Mathis R.

J Med Chem. 1993 Jan 22;36(2):181-95.

PMID:
8423591
16.

1,3-dioxolanylpurine nucleosides (2R,4R) and (2R,4S) with selective anti-HIV-1 activity in human lymphocytes.

Kim HO, Schinazi RF, Nampalli S, Shanmuganathan K, Cannon DL, Alves AJ, Jeong LS, Beach JW, Chu CK.

J Med Chem. 1993 Jan 8;36(1):30-7.

PMID:
8421287
17.

Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication.

Chang CN, Doong SL, Zhou JH, Beach JW, Jeong LS, Chu CK, Tsai CH, Cheng YC, Liotta D, Schinazi R.

J Biol Chem. 1992 Jul 15;267(20):13938-42. Erratum in: J Biol Chem 1992 Nov 25;267(33):24148.

18.

Asymmetric synthesis of 1,3-dioxolane-pyrimidine nucleosides and their anti-HIV activity.

Kim HO, Ahn SK, Alves AJ, Beach JW, Jeong LS, Choi BG, Van Roey P, Schinazi RF, Chu CK.

J Med Chem. 1992 May 29;35(11):1987-95.

PMID:
1597854
19.

Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes.

Schinazi RF, Chu CK, Peck A, McMillan A, Mathis R, Cannon D, Jeong LS, Beach JW, Choi WB, Yeola S, et al.

Antimicrob Agents Chemother. 1992 Mar;36(3):672-6.

20.
21.

Synthesis and structure-activity relationships of 6-substituted 2',3'-dideoxypurine nucleosides as potential anti-human immunodeficiency virus agents.

Chu CK, Ullas GV, Jeong LS, Ahn SK, Doboszewski B, Lin ZX, Beach JW, Schinazi RF.

J Med Chem. 1990 Jun;33(6):1553-61.

PMID:
2342052

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