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Items: 20

1.

Length of Uninterrupted CAG, Independent of Polyglutamine Size, Results in Increased Somatic Instability, Hastening Onset of Huntington Disease.

Wright GEB, Collins JA, Kay C, McDonald C, Dolzhenko E, Xia Q, Bečanović K, Drögemöller BI, Semaka A, Nguyen CM, Trost B, Richards F, Bijlsma EK, Squitieri F, Ross CJD, Scherer SW, Eberle MA, Yuen RKC, Hayden MR.

Am J Hum Genet. 2019 Jun 6;104(6):1116-1126. doi: 10.1016/j.ajhg.2019.04.007. Epub 2019 May 16.

PMID:
31104771
2.

Computational Analysis of Transcriptional Regulation Sites at the HTT Gene Locus.

De Souza RAG, Kosior N, Thomson SB, Mathelier A, Zhang AW, Bečanović K, Wasserman WW, Leavitt BR.

J Huntingtons Dis. 2018;7(3):223-237. doi: 10.3233/JHD-170272.

PMID:
30103339
3.

A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease.

Bečanović K, Nørremølle A, Neal SJ, Kay C, Collins JA, Arenillas D, Lilja T, Gaudenzi G, Manoharan S, Doty CN, Beck J, Lahiri N, Portales-Casamar E, Warby SC, Connolly C, De Souza RA; REGISTRY Investigators of the European Huntington's Disease Network, Tabrizi SJ, Hermanson O, Langbehn DR, Hayden MR, Wasserman WW, Leavitt BR.

Nat Neurosci. 2015 Jun;18(6):807-16. doi: 10.1038/nn.4014. Epub 2015 May 4.

PMID:
25938884
4.

p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin.

Ehrnhoefer DE, Skotte NH, Ladha S, Nguyen YT, Qiu X, Deng Y, Huynh KT, Engemann S, Nielsen SM, Becanovic K, Leavitt BR, Hasholt L, Hayden MR.

Hum Mol Genet. 2014 Feb 1;23(3):717-29. doi: 10.1093/hmg/ddt458. Epub 2013 Sep 18.

PMID:
24070868
5.

Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease.

Tang B, Becanovic K, Desplats PA, Spencer B, Hill AM, Connolly C, Masliah E, Leavitt BR, Thomas EA.

Hum Mol Genet. 2012 Jul 15;21(14):3097-111. doi: 10.1093/hmg/dds132. Epub 2012 Apr 6.

6.

IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation.

Beyeen AD, Adzemovic MZ, Ockinger J, Stridh P, Becanovic K, Laaksonen H, Lassmann H, Harris RA, Hillert J, Alfredsson L, Celius EG, Harbo HF, Kockum I, Jagodic M, Olsson T.

J Immunol. 2010 Dec 1;185(11):6883-90. doi: 10.4049/jimmunol.1001392. Epub 2010 Nov 1.

7.

Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat.

Stridh P, Thessen Hedreul M, Beyeen AD, Adzemovic MZ, Laaksonen H, Gillett A, Ockinger J, Marta M, Lassmann H, Becanovic K, Jagodic M, Olsson T.

PLoS One. 2010 Sep 15;5(9):e12716. doi: 10.1371/journal.pone.0012716.

8.

Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis.

Becanovic K, Pouladi MA, Lim RS, Kuhn A, Pavlidis P, Luthi-Carter R, Hayden MR, Leavitt BR.

Hum Mol Genet. 2010 Apr 15;19(8):1438-52. doi: 10.1093/hmg/ddq018. Epub 2010 Jan 20.

9.

Expression analysis of novel striatal-enriched genes in Huntington disease.

Mazarei G, Neal SJ, Becanovic K, Luthi-Carter R, Simpson EM, Leavitt BR.

Hum Mol Genet. 2010 Feb 15;19(4):609-22. doi: 10.1093/hmg/ddp527. Epub 2009 Nov 23.

10.

Multiple loci comprising immune-related genes regulate experimental neuroinflammation.

Marta M, Stridh P, Becanovic K, Gillett A, Ockinger J, Lorentzen JC, Jagodic M, Olsson T.

Genes Immun. 2010 Jan;11(1):21-36. doi: 10.1038/gene.2009.62. Epub 2009 Aug 13.

PMID:
19675581
11.

Definition of arthritis candidate risk genes by combining rat linkage-mapping results with human case-control association data.

Bäckdahl L, Guo JP, Jagodic M, Becanovic K, Ding B, Olsson T, Lorentzen JC.

Ann Rheum Dis. 2009 Dec;68(12):1925-32. doi: 10.1136/ard.2008.090803. Epub 2008 Dec 9.

PMID:
19066175
12.

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.

Kuhn A, Goldstein DR, Hodges A, Strand AD, Sengstag T, Kooperberg C, Becanovic K, Pouladi MA, Sathasivam K, Cha JH, Hannan AJ, Hayden MR, Leavitt BR, Dunnett SB, Ferrante RJ, Albin R, Shelbourne P, Delorenzi M, Augood SJ, Faull RL, Olson JM, Bates GP, Jones L, Luthi-Carter R.

Hum Mol Genet. 2007 Aug 1;16(15):1845-61. Epub 2007 May 21.

PMID:
17519223
13.

Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis.

Becanovic K, Jagodic M, Sheng JR, Dahlman I, Aboul-Enein F, Wallstrom E, Olofsson P, Holmdahl R, Lassmann H, Olsson T.

J Immunol. 2006 May 15;176(10):6055-64.

14.

Eae19, a new locus on rat chromosome 15 regulating experimental autoimmune encephalomyelitis.

Sheng JR, Jagodic M, Dahlman I, Becanovic K, Nohra R, Marta M, Iacobaeus E, Olsson T, Wallström E.

Genetics. 2005 May;170(1):283-9. Epub 2005 Feb 16.

15.

Resolution of a 16.8-Mb autoimmunity-regulating rat chromosome 4 region into multiple encephalomyelitis quantitative trait loci and evidence for epistasis.

Jagodic M, Marta M, Becanovic K, Sheng JR, Nohra R, Olsson T, Lorentzen JC.

J Immunol. 2005 Jan 15;174(2):918-24.

16.

An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci.

Jagodic M, Becanovic K, Sheng JR, Wu X, Bäckdahl L, Lorentzen JC, Wallström E, Olsson T.

J Immunol. 2004 Jul 15;173(2):1366-73.

17.

Current gene-mapping strategies in experimental models of multiple sclerosis.

Becanovic K, Jagodic M, Wallström E, Olsson T.

Scand J Immunol. 2004 Jul-Aug;60(1-2):39-51. Review.

18.

Paradoxical effects of arthritis-regulating chromosome 4 regions on myelin oligodendrocyte glycoprotein-induced encephalomyelitis in congenic rats.

Becanovic K, Bäckdahl L, Wallström E, Aboul-Enein F, Lassmann H, Olsson T, Lorentzen JC.

Eur J Immunol. 2003 Jul;33(7):1907-16.

19.

New loci regulating rat myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis.

Becanovic K, Wallstrom E, Kornek B, Glaser A, Broman KW, Dahlman I, Olofsson P, Holmdahl R, Luthman H, Lassmann H, Olsson T.

J Immunol. 2003 Jan 15;170(2):1062-9.

20.

Identification of rat quantitative trait loci that regulate LPS-induced pro-inflammatory cytokine responses.

Xu H, Wallstrom E, Becanovic K, Dahlman I, Lorentzen JC.

Scand J Immunol. 2002 Sep;56(3):248-53.

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