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Items: 1 to 50 of 419

1.

Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3.

Le Clorennec C, Bazin H, Dubreuil O, Larbouret C, Ogier C, Lazrek Y, Garambois V, Poul MA, Mondon P, Barret JM, Mathis G, Prost JF, Pèlegrin A, Chardès T.

Mol Cancer Ther. 2017 Jul;16(7):1312-1323. doi: 10.1158/1535-7163.MCT-16-0886. Epub 2017 May 15.

2.

Evaluation of novel synthetic TLR7/8 agonists as vaccine adjuvants.

Smith AJ, Li Y, Bazin HG, St-Jean JR, Larocque D, Evans JT, Baldridge JR.

Vaccine. 2016 Aug 5;34(36):4304-12. doi: 10.1016/j.vaccine.2016.06.080. Epub 2016 Jul 9.

3.

Structural requirements for TLR7-selective signaling by 9-(4-piperidinylalkyl)-8-oxoadenine derivatives.

Bazin HG, Li Y, Khalaf JK, Mwakwari S, Livesay MT, Evans JT, Johnson DA.

Bioorg Med Chem Lett. 2015 Mar 15;25(6):1318-23. doi: 10.1016/j.bmcl.2015.01.037. Epub 2015 Jan 31.

4.

Examination of HER3 targeting in cancer using monoclonal antibodies.

Gaborit N, Abdul-Hai A, Mancini M, Lindzen M, Lavi S, Leitner O, Mounier L, Chentouf M, Dunoyer S, Ghosh M, Larbouret C, Chardès T, Bazin H, Pèlegrin A, Sela M, Yarden Y.

Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):839-44. doi: 10.1073/pnas.1423645112. Epub 2015 Jan 6.

5.

Characterization of TRIF selectivity in the AGP class of lipid A mimetics: role of secondary lipid chains.

Khalaf JK, Bowen WS, Bazin HG, Ryter KT, Livesay MT, Ward JR, Evans JT, Johnson DA.

Bioorg Med Chem Lett. 2015 Feb 1;25(3):547-53. doi: 10.1016/j.bmcl.2014.12.024. Epub 2014 Dec 17.

6.

Evaluation of the dimerization profiles of HER tyrosine kinases by time-resolved Förster resonance energy transfer (TR-FRET).

Lopez-Crapez E, Ho-Pun-Cheung A, Garnero P, Bazin H.

Methods Mol Biol. 2015;1233:45-55. doi: 10.1007/978-1-4939-1789-1_5.

PMID:
25319888
7.

HER3 as biomarker and therapeutic target in pancreatic cancer: new insights in pertuzumab therapy in preclinical models.

Thomas G, Chardès T, Gaborit N, Mollevi C, Leconet W, Robert B, Radosevic-Robin N, Penault-Llorca F, Gongora C, Colombo PE, Lazrek Y, Bras-Goncalves R, Savina A, Azria D, Bazin H, Pèlegrin A, Larbouret C.

Oncotarget. 2014 Aug 30;5(16):7138-48.

8.

Luminescent lanthanide cryptates: from the bench to the bedside.

Zwier JM, Bazin H, Lamarque L, Mathis G.

Inorg Chem. 2014 Feb 17;53(4):1854-66. doi: 10.1021/ic402234k. Epub 2014 Jan 6. Review.

PMID:
24392868
9.

Endogenous morphine-6-glucuronide (M6G) is present in the plasma of patients: validation of a specific anti-M6G antibody for clinical and basic research.

Laux-Biehlmann A, Chung H, Mouheiche J, Vérièpe J, Delalande F, Lamshöft M, Welters ID, Soldevila S, Bazin H, Lamarque L, Van Dorsselaer A, Poisbeau P, Schneider F, Goumon Y, Garnero P.

Biofactors. 2014 Jan-Feb;40(1):113-20. doi: 10.1002/biof.1107. Epub 2013 Jul 17.

PMID:
23861301
10.

Synthesis and optical properties of macrocyclic lanthanide(III) chelates as new reagents for luminescent biolabeling.

Deslandes S, Galaup C, Poole R, Mestre-Voegtlé B, Soldevila S, Leygue N, Bazin H, Lamarque L, Picard C.

Org Biomol Chem. 2012 Nov 14;10(42):8509-23. doi: 10.1039/c2ob26311d. Epub 2012 Sep 25.

PMID:
23011114
11.

Quantification of HER expression and dimerization in patients' tumor samples using time-resolved Förster resonance energy transfer.

Ho-Pun-Cheung A, Bazin H, Gaborit N, Larbouret C, Garnero P, Assenat E, Castan F, Bascoul-Mollevi C, Ramos J, Ychou M, Pèlegrin A, Mathis G, Lopez-Crapez E.

PLoS One. 2012;7(7):e37065. doi: 10.1371/journal.pone.0037065. Epub 2012 Jul 19.

12.

In vivo phage display to identify new human antibody fragments homing to atherosclerotic endothelial and subendothelial tissues [corrected].

Deramchia K, Jacobin-Valat MJ, Vallet A, Bazin H, Santarelli X, Sanchez S, Dos Santos P, Franconi JM, Claverol S, Bonetto S, Clofent-Sanchez G.

Am J Pathol. 2012 Jun;180(6):2576-89. doi: 10.1016/j.ajpath.2012.02.013. Epub 2012 Apr 17. Erratum in: Am J Pathol. 2012 Nov;181(5):1889.

PMID:
22521648
13.

[History of vaccine refusal].

Bazin H.

Bull Acad Natl Med. 2010 Apr-May;194(4-5):705-18. French.

PMID:
21568044
14.

Time-resolved fluorescence resonance energy transfer (TR-FRET) to analyze the disruption of EGFR/HER2 dimers: a new method to evaluate the efficiency of targeted therapy using monoclonal antibodies.

Gaborit N, Larbouret C, Vallaghe J, Peyrusson F, Bascoul-Mollevi C, Crapez E, Azria D, Chardès T, Poul MA, Mathis G, Bazin H, Pèlegrin A.

J Biol Chem. 2011 Apr 1;286(13):11337-45. doi: 10.1074/jbc.M111.223503. Epub 2011 Jan 31.

15.

Time-resolved FRET between GPCR ligands reveals oligomers in native tissues.

Albizu L, Cottet M, Kralikova M, Stoev S, Seyer R, Brabet I, Roux T, Bazin H, Bourrier E, Lamarque L, Breton C, Rives ML, Newman A, Javitch J, Trinquet E, Manning M, Pin JP, Mouillac B, Durroux T.

Nat Chem Biol. 2010 Aug;6(8):587-94. doi: 10.1038/nchembio.396. Epub 2010 Jul 11.

16.

The 'Ethereal' nature of TLR4 agonism and antagonism in the AGP class of lipid A mimetics.

Bazin HG, Murray TJ, Bowen WS, Mozaffarian A, Fling SP, Bess LS, Livesay MT, Arnold JS, Johnson CL, Ryter KT, Cluff CW, Evans JT, Johnson DA.

Bioorg Med Chem Lett. 2008 Oct 15;18(20):5350-4. doi: 10.1016/j.bmcl.2008.09.060. Epub 2008 Sep 19.

PMID:
18835160
17.

A homogeneous resonance energy transfer-based assay to monitor MutS/DNA interactions.

Lopez-Crapez E, Malinge JM, Gatchitch F, Casano L, Langlois T, Pugnière M, Roquet F, Mathis G, Bazin H.

Anal Biochem. 2008 Dec 15;383(2):301-6. doi: 10.1016/j.ab.2008.09.004. Epub 2008 Sep 11.

PMID:
18824153
18.

Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization.

Maurel D, Comps-Agrar L, Brock C, Rives ML, Bourrier E, Ayoub MA, Bazin H, Tinel N, Durroux T, Prézeau L, Trinquet E, Pin JP.

Nat Methods. 2008 Jun;5(6):561-7. doi: 10.1038/nmeth.1213. Epub 2008 May 18.

19.

Toward efficient drug screening by homogeneous assays based on the development of new fluorescent vasopressin and oxytocin receptor ligands.

Albizu L, Teppaz G, Seyer R, Bazin H, Ansanay H, Manning M, Mouillac B, Durroux T.

J Med Chem. 2007 Oct 4;50(20):4976-85. Epub 2007 Sep 12.

PMID:
17850055
20.

Luminescent Eu(III) and Gd(III) trisbipyridine cryptates: experimental and theoretical study of the substituent effects.

Guillaumont D, Bazin H, Benech JM, Boyer M, Mathis G.

Chemphyschem. 2007 Feb 19;8(3):480-8.

PMID:
17226873
21.

D-myo-inositol 1-phosphate as a surrogate of D-myo-inositol 1,4,5-tris phosphate to monitor G protein-coupled receptor activation.

Trinquet E, Fink M, Bazin H, Grillet F, Maurin F, Bourrier E, Ansanay H, Leroy C, Michaud A, Durroux T, Maurel D, Malhaire F, Goudet C, Pin JP, Naval M, Hernout O, Chrétien F, Chapleur Y, Mathis G.

Anal Biochem. 2006 Nov 1;358(1):126-35. Epub 2006 Aug 30.

PMID:
16965760
22.

Long-term results (10 years) of a prospective trial comparing Lo-tact-1 monoclonal antibody and anti-thymocyte globulin induction therapy in kidney transplantation.

Beaudreuil S, Durrbach A, Noury J, Ducot B, Kriaa F, Bazin H, Charpentier B.

Transpl Int. 2006 Oct;19(10):814-20.

23.

Positively charged GdIII cryptates: slow, associative water exchange.

Burai L, Tóth E, Bazin H, Benmelouka M, Jászberényi Z, Helm L, Merbach AE.

Dalton Trans. 2006 Jan 28;(4):629-34. Epub 2005 Oct 31.

PMID:
16402151
24.

Anti-CD2 monoclonal antibody and tacrolimus in adult liver transplantation.

Lerut J, Van Thuyne V, Mathijs J, Lemaire J, Talpe S, Roggen F, Ciccarelli O, Zuckermann M, Goffette P, Hope J, Gianello P, Bazin H, Cornet A, Rahier J, Latinne D.

Transplantation. 2005 Nov 15;80(9):1186-93.

PMID:
16314784
25.

The relation between p70S6k expression in lymphocytes and the decline of cognitive test scores in patients with Alzheimer disease.

Paccalin M, Pain-Barc S, Pluchon C, Paul C, Bazin H, Gil R, Hugon J.

Arch Intern Med. 2005 Nov 14;165(20):2428-9. No abstract available.

PMID:
16287775
26.

Microwaves synthesis of solid supports for the synthesis of 3'-aminoalkyl oligodeoxynucleotides.

Goussu C, Vasseur JJ, Bazin H, Morvan F.

Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):623-7.

PMID:
16248000
27.

A separation-free assay for the detection of mutations: combination of homogeneous time-resolved fluorescence and minisequencing.

Lopez-Crapez E, Bazin H, Chevalier J, Trinquet E, Grenier J, Mathis G.

Hum Mutat. 2005 May;25(5):468-75.

PMID:
15832307
28.

Optimized synthesis of functionalized fluorescent oligodeoxynucleotides for protein labeling.

Goussu C, Vasseur JJ, Bazin H, Trinquet E, Maurin F, Morvan F.

Bioconjug Chem. 2005 Mar-Apr;16(2):465-70.

PMID:
15769102
29.

The anti-CD2 monoclonal antibody BTI-322 generates unresponsiveness by activation-associated T cell depletion.

Xu Y, Kolber-Simonds D, Hope JA, Bazin H, Latinne D, Monroy R, White-Scharf ME, Schuurman HJ.

Clin Exp Immunol. 2004 Dec;138(3):476-83.

30.

A homogeneous time-resolved fluorescence detection of telomerase activity.

Gabourdes M, Bourgine V, Mathis G, Bazin H, Alpha-Bazin B.

Anal Biochem. 2004 Oct 1;333(1):105-13.

PMID:
15351286
31.
32.

In vitro and in vivo investigation of a novel monoclonal antibody to plasma cells (W5 mAb).

Harper D, Gollackner B, Xu Y, Calderhead D, Ryan D, Li W, Cheng J, Wu C, Moran K, Latinne D, Bazin H, White-Scharf ME, Cooper DK, Awwad M.

Xenotransplantation. 2004 Jan;11(1):78-90. Erratum in: Xenotransplantation. 2004 May;11(3):305. Chang, J [corrected to Cheng, J].

PMID:
14962296
33.

Cell-mediated cytotoxicity to porcine aortic endothelial cells is not dependent on galactosyl residues when baboon peripheral blood lymphocytes are previously primed with pig xenoantigens.

Dehoux JP, Nizet Y, de la Parra B, Lecuivre C, Vergauwen M, Bazin H, Latinne D, Gianello P.

Transplantation. 2003 Dec 27;76(12):1675-80.

PMID:
14688514
34.

Immunoglobulin E is not required for but enhances airway inflammation and hyperresponsiveness.

Itami DM, Latinne D, Bazin H, Garcia ML, Perini A, Martins MA, Macedo MS, Macedo-Soares MF.

Allergy. 2003 Nov;58(11):1117-24.

PMID:
14616121
35.

A brief history of the prevention of infectious diseases by immunisations.

Bazin H.

Comp Immunol Microbiol Infect Dis. 2003 Oct;26(5-6):293-308.

PMID:
12818618
37.

Characterization of baboon anti-porcine IgG antibodies during acute vascular rejection of porcine kidney xenograft.

Dehoux JP, de la Parra B, Latinne D, Bazin H, Gianello P.

Xenotransplantation. 2002 Sep;9(5):338-49.

PMID:
12199865
38.

Inhibition of apolipoprotein E-related neurotoxicity by glycosaminoglycans and their oligosaccharides.

Bazin HG, Marques MA, Owens AP 3rd, Linhardt RJ, Crutcher KA.

Biochemistry. 2002 Jun 25;41(25):8203-11.

PMID:
12069613
39.

Ratio between Epstein-Barr viral load and anti-Epstein-Barr virus specific T-cell response as a predictive marker of posttransplant lymphoproliferative disease.

Smets F, Latinne D, Bazin H, Reding R, Otte JB, Buts JP, Sokal EM.

Transplantation. 2002 May 27;73(10):1603-10.

PMID:
12042647
40.

Time resolved amplification of cryptate emission: a versatile technology to trace biomolecular interactions.

Bazin H, Trinquet E, Mathis G.

J Biotechnol. 2002 Jan;82(3):233-50. Review.

PMID:
11999692
41.

The ethics of vaccine usage in society: lessons from the past.

Bazin H.

Endeavour. 2001 Sep;25(3):104-8.

PMID:
11725304
42.
43.

Homogeneous time resolved fluorescence resonance energy transfer using rare earth cryptates as a tool for probing molecular interactions in biology.

Bazin H, Préaudat M, Trinquet E, Mathis G.

Spectrochim Acta A Mol Biomol Spectrosc. 2001 Sep 14;57(11):2197-211. Review.

PMID:
11603838
44.
45.

The ethics of vaccine usage in society: lessons from the past. Commentary.

Bazin H.

Curr Opin Immunol. 2001 Aug;13(4):505-10. No abstract available.

PMID:
11498309
46.

Effect in vitro and in vivo of a rat anti-CD2 monoclonal antibody (LO-CD2b) on pig-to-baboon xenogeneic cellular (T and natural killer cells) immune response.

Dehoux JP, de la Parra B, Latinne D, Bazin H, Gianello P.

Xenotransplantation. 2001 Aug;8(3):193-201.

PMID:
11472627
47.

A homogeneous europium cryptate-based assay for the diagnosis of mutations by time-resolved fluorescence resonance energy transfer.

Lopez-Crapez E, Bazin H, Andre E, Noletti J, Grenier J, Mathis G.

Nucleic Acids Res. 2001 Jul 15;29(14):E70.

48.

Enzymatic preparation of heparin disaccharides as building blocks in glycosaminoglycan synthesis.

Kim YS, Thanawiroon C, Bazin HG, Kerns RJ, Linhard RJ.

Prep Biochem Biotechnol. 2001 May;31(2):113-24.

PMID:
11426699
49.

Europium cryptate labeled deoxyuridine-triphosphate analog: synthesis and enzymatic incorporation.

Alpha-Bazin B, Bazin H, Guillemer S, Sauvaigo S, Mathis G.

Nucleosides Nucleotides Nucleic Acids. 2000 Sep;19(9):1463-74.

PMID:
11092315
50.

B-Cell suppression in adult mice injected with anti-delta followed by anti-mu mAb.

Chentoufi AA, Nizet Y, Havaux X, Nisol F, Bazin H, Latinne D.

Cell Immunol. 2000 Oct 10;205(1):40-51.

PMID:
11078606

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