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Items: 21


FMRP recruitment of β-catenin to the translation pre-initiation complex represses translation.

Ehyai S, Miyake T, Williams D, Vinayak J, Bayfield MA, McDermott JC.

EMBO Rep. 2018 Oct 25. pii: e45536. doi: 10.15252/embr.201745536. [Epub ahead of print]


Human La binds mRNAs through contacts to the poly(A) tail.

Vinayak J, Marrella SA, Hussain RH, Rozenfeld L, Solomon K, Bayfield MA.

Nucleic Acids Res. 2018 May 4;46(8):4228-4240. doi: 10.1093/nar/gky090.


The RNA chaperone La promotes pre-tRNA maturation via indiscriminate binding of both native and misfolded targets.

Vakiloroayaei A, Shah NS, Oeffinger M, Bayfield MA.

Nucleic Acids Res. 2017 Nov 2;45(19):11341-11355. doi: 10.1093/nar/gkx764.


Distinct Dynamic Modes Enable the Engagement of Dissimilar Ligands in a Promiscuous Atypical RNA Recognition Motif.

Brown KA, Sharifi S, Hussain R, Donaldson L, Bayfield MA, Wilson DJ.

Biochemistry. 2016 Dec 27;55(51):7141-7150. doi: 10.1021/acs.biochem.6b00995. Epub 2016 Dec 13.


Imprint Desorption Electrospray Ionization Mass Spectrometry Imaging for Monitoring Secondary Metabolites Production during Antagonistic Interaction of Fungi.

Tata A, Perez C, Campos ML, Bayfield MA, Eberlin MN, Ifa DR.

Anal Chem. 2015 Dec 15;87(24):12298-305. doi: 10.1021/acs.analchem.5b03614. Epub 2015 Dec 4.


Analysis of metabolic changes in plant pathosystems by imprint imaging DESI-MS.

Tata A, Perez CJ, Hamid TS, Bayfield MA, Ifa DR.

J Am Soc Mass Spectrom. 2015 Apr;26(4):641-8. doi: 10.1007/s13361-014-1039-0. Epub 2014 Dec 16.


Conservation of RNA chaperone activity of the human La-related proteins 4, 6 and 7.

Hussain RH, Zawawi M, Bayfield MA.

Nucleic Acids Res. 2013 Oct;41(18):8715-25. doi: 10.1093/nar/gkt649. Epub 2013 Jul 25.


RNA chaperone activity of human La protein is mediated by variant RNA recognition motif.

Naeeni AR, Conte MR, Bayfield MA.

J Biol Chem. 2012 Feb 17;287(8):5472-82. doi: 10.1074/jbc.M111.276071. Epub 2011 Dec 27.


Comparative whole genome sequencing reveals phenotypic tRNA gene duplication in spontaneous Schizosaccharomyces pombe La mutants.

Iben JR, Epstein JA, Bayfield MA, Bruinsma MW, Hasson S, Bacikova D, Ahmad D, Rockwell D, Kittler EL, Zapp ML, Maraia RJ.

Nucleic Acids Res. 2011 Jun;39(11):4728-42. doi: 10.1093/nar/gkr066. Epub 2011 Feb 11.


Conserved and divergent features of the structure and function of La and La-related proteins (LARPs).

Bayfield MA, Yang R, Maraia RJ.

Biochim Biophys Acta. 2010 May-Jun;1799(5-6):365-78. doi: 10.1016/j.bbagrm.2010.01.011. Epub 2010 Feb 2. Review.


Precursor-product discrimination by La protein during tRNA metabolism.

Bayfield MA, Maraia RJ.

Nat Struct Mol Biol. 2009 Apr;16(4):430-7. doi: 10.1038/nsmb.1573. Epub 2009 Mar 15.


Cellular La protein shields nonsegmented negative-strand RNA viral leader RNA from RIG-I and enhances virus growth by diverse mechanisms.

Bitko V, Musiyenko A, Bayfield MA, Maraia RJ, Barik S.

J Virol. 2008 Aug;82(16):7977-87. doi: 10.1128/JVI.02762-07. Epub 2008 Jun 11.


It's a mod mod tRNA world.

Maraia RJ, Blewett NH, Bayfield MA.

Nat Chem Biol. 2008 Mar;4(3):162-4. doi: 10.1038/nchembio0308-162. No abstract available.


A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis.

He N, Jahchan NS, Hong E, Li Q, Bayfield MA, Maraia RJ, Luo K, Zhou Q.

Mol Cell. 2008 Mar 14;29(5):588-99. doi: 10.1016/j.molcel.2008.01.003. Epub 2008 Jan 31.


Conservation of a masked nuclear export activity of La proteins and its effects on tRNA maturation.

Bayfield MA, Kaiser TE, Intine RV, Maraia RJ.

Mol Cell Biol. 2007 May;27(9):3303-12. Epub 2007 Feb 16.


Separate RNA-binding surfaces on the multifunctional La protein mediate distinguishable activities in tRNA maturation.

Huang Y, Bayfield MA, Intine RV, Maraia RJ.

Nat Struct Mol Biol. 2006 Jul;13(7):611-8. Epub 2006 Jun 25.


The La protein-RNA complex surfaces.

Maraia RJ, Bayfield MA.

Mol Cell. 2006 Jan 20;21(2):149-52. Review.


Probing ribosome structure and function by mutagenesis.

Gregory ST, Bayfield MA, O'Connor M, Thompson J, Dahlberg AE.

Cold Spring Harb Symp Quant Biol. 2001;66:101-8. Review. No abstract available.


A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition.

Bayfield MA, Dahlberg AE, Schulmeister U, Dorner S, Barta A.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10096-101. Epub 2001 Aug 21.


Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit.

Thompson J, Kim DF, O'Connor M, Lieberman KR, Bayfield MA, Gregory ST, Green R, Noller HF, Dahlberg AE.

Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9002-7. Epub 2001 Jul 24.

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