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Items: 39


Extracellular vesicles from mature dendritic cells (DC) differentiate monocytes into immature DC.

Schierer S, Ostalecki C, Zinser E, Lamprecht R, Plosnita B, Stich L, Dörrie J, Lutz MB, Schuler G, Baur AS.

Life Sci Alliance. 2018 Dec 3;1(6):e201800093. doi: 10.26508/lsa.201800093. eCollection 2018 Dec.


HIV Activates the Tyrosine Kinase Hck to Secrete ADAM Protease-Containing Extracellular Vesicles.

Lee JH, Ostalecki C, Zhao Z, Kesti T, Bruns H, Simon B, Harrer T, Saksela K, Baur AS.

EBioMedicine. 2018 Feb;28:151-161. doi: 10.1016/j.ebiom.2018.01.004. Epub 2018 Jan 4. No abstract available.


Multiepitope tissue analysis reveals SPPL3-mediated ADAM10 activation as a key step in the transformation of melanocytes.

Ostalecki C, Lee JH, Dindorf J, Collenburg L, Schierer S, Simon B, Schliep S, Kremmer E, Schuler G, Baur AS.

Sci Signal. 2017 Mar 14;10(470). pii: eaai8288. doi: 10.1126/scisignal.aai8288.


HIV Nef- and Notch1-dependent Endocytosis of ADAM17 Induces Vesicular TNF Secretion in Chronic HIV Infection.

Ostalecki C, Wittki S, Lee JH, Geist MM, Tibroni N, Harrer T, Schuler G, Fackler OT, Baur AS.

EBioMedicine. 2016 Nov;13:294-304. doi: 10.1016/j.ebiom.2016.10.027. Epub 2016 Oct 19.


HIV-Nef and ADAM17-Containing Plasma Extracellular Vesicles Induce and Correlate with Immune Pathogenesis in Chronic HIV Infection.

Lee JH, Schierer S, Blume K, Dindorf J, Wittki S, Xiang W, Ostalecki C, Koliha N, Wild S, Schuler G, Fackler OT, Saksela K, Harrer T, Baur AS.

EBioMedicine. 2016 Apr;6:103-113. doi: 10.1016/j.ebiom.2016.03.004. Epub 2016 Mar 3.


Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak® on CD25+ cells.

Lutz MB, Baur AS, Schuler-Thurner B, Schuler G.

Oncoimmunology. 2014 Mar 17;3:e28223. eCollection 2014.


Denileukin diftitox (ONTAK) induces a tolerogenic phenotype in dendritic cells and stimulates survival of resting Treg.

Baur AS, Lutz MB, Schierer S, Beltrame L, Theiner G, Zinser E, Ostalecki C, Heidkamp G, Haendle I, Erdmann M, Wiesinger M, Leisgang W, Gross S, Pommer AJ, Kämpgen E, Dudziak D, Steinkasserer A, Cavalieri D, Schuler-Thurner B, Schuler G.

Blood. 2013 Sep 26;122(13):2185-94. doi: 10.1182/blood-2012-09-456988. Epub 2013 Aug 19.


HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases.

Lee JH, Wittki S, Bräu T, Dreyer FS, Krätzel K, Dindorf J, Johnston IC, Gross S, Kremmer E, Zeidler R, Schlötzer-Schrehardt U, Lichtenheld M, Saksela K, Harrer T, Schuler G, Federico M, Baur AS.

Mol Cell. 2013 Feb 21;49(4):668-79. doi: 10.1016/j.molcel.2012.12.004. Epub 2013 Jan 11.


HIV-Nef and AIDS pathogenesis: are we barking up the wrong tree?

Baur AS.

Trends Microbiol. 2011 Sep;19(9):435-40. doi: 10.1016/j.tim.2011.06.002. Epub 2011 Jul 25.


Human dendritic cells efficiently phagocytose adenoviral oncolysate but require additional stimulation to mature.

Schierer S, Hesse A, Knippertz I, Kaempgen E, Baur AS, Schuler G, Steinkasserer A, Nettelbeck DM.

Int J Cancer. 2012 Apr 1;130(7):1682-94. doi: 10.1002/ijc.26176. Epub 2011 Aug 3.


Massive secretion by T cells is caused by HIV Nef in infected cells and by Nef transfer to bystander cells.

Muratori C, Cavallin LE, Krätzel K, Tinari A, De Milito A, Fais S, D'Aloja P, Federico M, Vullo V, Fomina A, Mesri EA, Superti F, Baur AS.

Cell Host Microbe. 2009 Sep 17;6(3):218-30. doi: 10.1016/j.chom.2009.06.009.


Induction of HIV transcription by Nef involves Lck activation and protein kinase C theta raft recruitment leading to activation of ERK1/2 but not NF kappa B.

Witte V, Laffert B, Gintschel P, Krautkrämer E, Blume K, Fackler OT, Baur AS.

J Immunol. 2008 Dec 15;181(12):8425-32. Erratum in: J Immunol. 2009 Mar 1;182(5):3327.


HIV Nef enhances Tat-mediated viral transcription through a hnRNP-K-nucleated signaling complex.

Wolf D, Witte V, Clark P, Blume K, Lichtenheld MG, Baur AS.

Cell Host Microbe. 2008 Oct 16;4(4):398-408. doi: 10.1016/j.chom.2008.08.013.


Novel (n)PKC kinases phosphorylate Nef for increased HIV transcription, replication and perinuclear targeting.

Wolf D, Giese SI, Witte V, Krautkrämer E, Trapp S, Sass G, Haller C, Blume K, Fackler OT, Baur AS.

Virology. 2008 Jan 5;370(1):45-54. Epub 2007 Sep 29.


Case study of intracerebral plasmacytoma as an initial presentation of multiple myeloma.

Wavre A, Baur AS, Betz M, Mühlematter D, Jotterand M, Zaman K, Ketterer N.

Neuro Oncol. 2007 Jul;9(3):370-2. Epub 2007 May 23.


Primary intracranial dural lymphoma of mucosa-associated lymphoid tissue (MALT) type: report of one case and review of the literature.

George AC, Ozsahin M, Janzer R, Agassis S, Meuli R, Baur AS, Frossard V, Leyvraz S, Ketterer N.

Bull Cancer. 2005 Jul;92(7):E51-6.


[Disseminated cryptococcosis as inaugural manifestation of AIDS].

Fournier Y, Bellini C, Baur AS, Waeber G, Cavassini M.

Praxis (Bern 1994). 2005 Jan 12;94(1-2):17-23. French.


HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane.

Witte V, Laffert B, Rosorius O, Lischka P, Blume K, Galler G, Stilper A, Willbold D, D'Aloja P, Sixt M, Kolanus J, Ott M, Kolanus W, Schuler G, Baur AS.

Mol Cell. 2004 Jan 30;13(2):179-90.


Contribution of IgH-PCR to the evaluation of B-cell lymphoma involvement in paraffin-embedded bone marrow biopsy specimens.

Braunschweig R, Baur AS, Delacrétaz F, Bricod C, Benhattar J.

Am J Clin Pathol. 2003 May;119(5):634-42.


Disseminated histoplasmosis in Switzerland: an unexpected cause of septic shock and multiple organ dysfunction.

Cavassini M, Lepori M, Baur AS, Bille J, Schaller MD, Marchetti O.

Intensive Care Med. 2002 Oct;28(10):1501-2. Epub 2002 Aug 1. No abstract available.


Live and let die: Nef functions beyond HIV replication.

Fackler OT, Baur AS.

Immunity. 2002 Apr;16(4):493-7. Review.


HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals.

Wolf D, Witte V, Laffert B, Blume K, Stromer E, Trapp S, d'Aloja P, Schürmann A, Baur AS.

Nat Med. 2001 Nov;7(11):1217-24.


A natural variability in the proline-rich motif of Nef modulates HIV-1 replication in primary T cells.

Fackler OT, Wolf D, Weber HO, Laffert B, D'Aloja P, Schuler-Thurner B, Geffin R, Saksela K, Geyer M, Peterlin BM, Schuler G, Baur AS.

Curr Biol. 2001 Aug 21;11(16):1294-9.


Nef from human immunodeficiency virus type 1(F12) inhibits viral production and infectivity.

Fackler OT, d'Aloja P, Baur AS, Federico M, Peterlin BM.

J Virol. 2001 Jul;75(14):6601-8.


Functional and structural defects in HIV type 1 nef genes derived from pediatric long-term survivors.

Geffin R, Wolf D, Müller R, Hill MD, Stellwag E, Freitag M, Sass G, Scott GB, Baur AS.

AIDS Res Hum Retroviruses. 2000 Nov 20;16(17):1855-68.


CD34/QBEND10 immunostaining in bone marrow biopsies: an additional parameter for the diagnosis and classification of myelodysplastic syndromes.

Baur AS, Meugé-Moraw C, Schmidt PM, Parlier V, Jotterand M, Delacrétaz F.

Eur J Haematol. 2000 Feb;64(2):71-9.


Rare occurrence of classical Hodgkin's disease as a T cell lymphoma.

Müschen M, Rajewsky K, Bräuninger A, Baur AS, Oudejans JJ, Roers A, Hansmann ML, Küppers R.

J Exp Med. 2000 Jan 17;191(2):387-94.


Frequent methylation silencing of p15(INK4b) (MTS2) and p16(INK4a) (MTS1) in B-cell and T-cell lymphomas.

Baur AS, Shaw P, Burri N, Delacrétaz F, Bosman FT, Chaubert P.

Blood. 1999 Sep 1;94(5):1773-81.


Chromosomal abnormalities in renal cell neoplasms associated with acquired renal cystic disease. A series studied by comparative genomic hybridization and fluorescence in situ hybridization.

Gronwald J, Baur AS, Holtgreve-Grez H, Jauch A, Mosimann F, Jichlinski P, Wauters JP, Cremer T, Guillou L.

J Pathol. 1999 Feb;187(3):308-12.


Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain.

Xu XN, Laffert B, Screaton GR, Kraft M, Wolf D, Kolanus W, Mongkolsapay J, McMichael AJ, Baur AS.

J Exp Med. 1999 May 3;189(9):1489-96.


Prognostic value of follicular dendritic cells in nodular sclerosing Hodgkin's disease.

Baur AS, Meugé-Moraw C, Michel G, Delacrétaz F.

Histopathology. 1998 Jun;32(6):512-20.


The N-terminus of Nef from HIV-1/SIV associates with a protein complex containing Lck and a serine kinase.

Baur AS, Sass G, Laffert B, Willbold D, Cheng-Mayer C, Peterlin BM.

Immunity. 1997 Mar;6(3):283-91.


A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity.

Sawai ET, Baur AS, Peterlin BM, Levy JA, Cheng-Mayer C.

J Biol Chem. 1995 Jun 23;270(25):15307-14.


HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization.

Baur AS, Sawai ET, Dazin P, Fantl WJ, Cheng-Mayer C, Peterlin BM.

Immunity. 1994 Aug;1(5):373-84.


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