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Items: 1 to 50 of 90

1.

Correction to Soft Hyaluronic Gels Promote Cell Spreading, Stress Fibers, Focal Adhesion, and Membrane Tension by Phosphoinositide Signaling, Not Traction Force.

Mandal K, Aroush DR, Graber ZT, Wu B, Park CY, Fredberg JJ, Guo W, Baumgart T, Janmey PA.

ACS Nano. 2019 Apr 23;13(4):4854. doi: 10.1021/acsnano.9b01435. Epub 2019 Mar 18. No abstract available.

PMID:
30883087
2.

Encoding biological recognition in a bicomponent cell-membrane mimic.

Rodriguez-Emmenegger C, Xiao Q, Kostina NY, Sherman SE, Rahimi K, Partridge BE, Li S, Sahoo D, Reveron Perez AM, Buzzacchera I, Han H, Kerzner M, Malhotra I, Möller M, Wilson CJ, Good MC, Goulian M, Baumgart T, Klein ML, Percec V.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5376-5382. doi: 10.1073/pnas.1821924116. Epub 2019 Feb 28.

3.

The 2018 biomembrane curvature and remodeling roadmap.

Bassereau P, Jin R, Baumgart T, Deserno M, Dimova R, Frolov VA, Bashkirov PV, Grubmüller H, Jahn R, Risselada HJ, Johannes L, Kozlov MM, Lipowsky R, Pucadyil TJ, Zeno WF, Stachowiak JC, Stamou D, Breuer A, Lauritsen L, Simon C, Sykes C, Voth GA, Weikl TR.

J Phys D Appl Phys. 2018 Aug;51(34). pii: 343001. doi: 10.1088/1361-6463/aacb98. Epub 2018 Jul 20.

4.

Correction: Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evaluation and Randomized Phase 1 Clinical Study.

Bekker P, Dairaghi D, Seitz L, Leleti M, Wang Y, Ertl L, Baumgart T, Shugarts S, Lohr L, Dang T, Miao S, Zeng Y, Fan P, Zhang P, Johnson D, Powers J, Jaen J, Charo I, Schall TJ.

PLoS One. 2019 Jan 4;14(1):e0210593. doi: 10.1371/journal.pone.0210593. eCollection 2019.

5.

Soft Hyaluronic Gels Promote Cell Spreading, Stress Fibers, Focal Adhesion, and Membrane Tension by Phosphoinositide Signaling, Not Traction Force.

Mandal K, Raz-Ben Aroush D, Graber ZT, Wu B, Park CY, Fredberg JJ, Guo W, Baumgart T, Janmey PA.

ACS Nano. 2019 Jan 22;13(1):203-214. doi: 10.1021/acsnano.8b05286. Epub 2018 Dec 14. Erratum in: ACS Nano. 2019 Apr 23;13(4):4854.

6.

Cell Membranes Resist Flow.

Shi Z, Graber ZT, Baumgart T, Stone HA, Cohen AE.

Cell. 2018 Dec 13;175(7):1769-1779.e13. doi: 10.1016/j.cell.2018.09.054. Epub 2018 Nov 1.

PMID:
30392960
7.

Screening Libraries of Amphiphilic Janus Dendrimers Based on Natural Phenolic Acids to Discover Monodisperse Unilamellar Dendrimersomes.

Buzzacchera I, Xiao Q, Han H, Rahimi K, Li S, Kostina NY, Toebes BJ, Wilner SE, Möller M, Rodriguez-Emmenegger C, Baumgart T, Wilson DA, Wilson CJ, Klein ML, Percec V.

Biomacromolecules. 2019 Feb 11;20(2):712-727. doi: 10.1021/acs.biomac.8b01405. Epub 2018 Nov 7.

8.

Correction to: α-Synuclein's Uniquely Long Amphipathic Helix Enhances its Membrane Binding and Remodeling Capacity.

Braun AR, Lacy MM, Ducas VC, Chen Z, Baumgart T, Rhoades E, Sachs JN.

J Membr Biol. 2018 Dec;251(5-6):757. doi: 10.1007/s00232-018-0042-y.

PMID:
30054671
9.

Dendrimersomes Exhibit Lamellar-to-Sponge Phase Transitions.

Wilner SE, Xiao Q, Graber ZT, Sherman SE, Percec V, Baumgart T.

Langmuir. 2018 May 15;34(19):5527-5534. doi: 10.1021/acs.langmuir.8b00275. Epub 2018 Apr 30.

10.

Kinetics of PTEN-mediated PI(3,4,5)P3 hydrolysis on solid supported membranes.

Liu C, Deb S, Ferreira VS, Xu E, Baumgart T.

PLoS One. 2018 Feb 15;13(2):e0192667. doi: 10.1371/journal.pone.0192667. eCollection 2018.

11.

Integrins Modulate T Cell Receptor Signaling by Constraining Actin Flow at the Immunological Synapse.

Jankowska KI, Williamson EK, Roy NH, Blumenthal D, Chandra V, Baumgart T, Burkhardt JK.

Front Immunol. 2018 Jan 18;9:25. doi: 10.3389/fimmu.2018.00025. eCollection 2018.

12.

Excess area dependent scaling behavior of nano-sized membrane tethers.

Ramakrishnan N, Sreeja KK, Roychoudhury A, Eckmann DM, Ayyaswamy PS, Baumgart T, Pucadyil T, Patil S, Weaver VM, Radhakrishnan R.

Phys Biol. 2018 Jan 11;15(2):026002. doi: 10.1088/1478-3975/aa9905.

13.

Janus dendrimersomes coassembled from fluorinated, hydrogenated, and hybrid Janus dendrimers as models for cell fusion and fission.

Xiao Q, Sherman SE, Wilner SE, Zhou X, Dazen C, Baumgart T, Reed EH, Hammer DA, Shinoda W, Klein ML, Percec V.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7045-E7053. doi: 10.1073/pnas.1708380114. Epub 2017 Aug 7.

14.

[Callus distraction and bone transport in the treatment of bone defects].

Baumgart R, Schuster B, Baumgart T.

Orthopade. 2017 Aug;46(8):673-680. doi: 10.1007/s00132-017-3441-3. Review. German.

PMID:
28725933
15.

Cations induce shape remodeling of negatively charged phospholipid membranes.

Graber ZT, Shi Z, Baumgart T.

Phys Chem Chem Phys. 2017 Jun 14;19(23):15285-15295. doi: 10.1039/c7cp00718c.

16.

Site-Specific Fluorescence Polarization for Studying the Disaggregation of α-Synuclein Fibrils by Small Molecules.

Haney CM, Cleveland CL, Wissner RF, Owei L, Robustelli J, Daniels MJ, Canyurt M, Rodriguez P, Ischiropoulos H, Baumgart T, Petersson EJ.

Biochemistry. 2017 Feb 7;56(5):683-691. doi: 10.1021/acs.biochem.6b01060. Epub 2016 Nov 11.

17.

Curvature-Driven Migration of Colloids on Tense Lipid Bilayers.

Li N, Sharifi-Mood N, Tu F, Lee D, Radhakrishnan R, Baumgart T, Stebe KJ.

Langmuir. 2017 Jan 17;33(2):600-610. doi: 10.1021/acs.langmuir.6b03406. Epub 2016 Dec 30.

18.

Membrane Shape Instability Induced by Protein Crowding.

Chen Z, Atefi E, Baumgart T.

Biophys J. 2016 Nov 1;111(9):1823-1826. doi: 10.1016/j.bpj.2016.09.039.

19.

The N-Terminal Amphipathic Helix of Endophilin Does Not Contribute to Its Molecular Curvature Generation Capacity.

Chen Z, Zhu C, Kuo CJ, Robustelli J, Baumgart T.

J Am Chem Soc. 2016 Nov 9;138(44):14616-14622. Epub 2016 Oct 28.

20.

Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evaluation and Randomized Phase 1 Clinical Study.

Bekker P, Dairaghi D, Seitz L, Leleti M, Wang Y, Ertl L, Baumgart T, Shugarts S, Lohr L, Dang T, Miao S, Zeng Y, Fan P, Zhang P, Johnson D, Powers J, Jaen J, Charo I, Schall TJ.

PLoS One. 2016 Oct 21;11(10):e0164646. doi: 10.1371/journal.pone.0164646. eCollection 2016. Erratum in: PLoS One. 2019 Jan 4;14(1):e0210593.

21.

Self-Sorting and Coassembly of Fluorinated, Hydrogenated, and Hybrid Janus Dendrimers into Dendrimersomes.

Xiao Q, Rubien JD, Wang Z, Reed EH, Hammer DA, Sahoo D, Heiney PA, Yadavalli SS, Goulian M, Wilner SE, Baumgart T, Vinogradov SA, Klein ML, Percec V.

J Am Chem Soc. 2016 Sep 28;138(38):12655-63. doi: 10.1021/jacs.6b08069. Epub 2016 Sep 14.

22.

DNA Island Formation on Binary Block Copolymer Vesicles.

Luo Q, Shi Z, Zhang Y, Chen XJ, Han SY, Baumgart T, Chenoweth DM, Park SJ.

J Am Chem Soc. 2016 Aug 17;138(32):10157-62. doi: 10.1021/jacs.6b04076. Epub 2016 Aug 3.

23.
24.

Application of a free-energy-landscape approach to study tension-dependent bilayer tubulation mediated by curvature-inducing proteins.

Tourdot RW, Ramakrishnan N, Baumgart T, Radhakrishnan R.

Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Oct;92(4):042715. doi: 10.1103/PhysRevE.92.042715. Epub 2015 Oct 29. Erratum in: Phys Rev E. 2016 May;93(5-2):059902.

25.

Regulation of membrane-shape transitions induced by I-BAR domains.

Chen Z, Shi Z, Baumgart T.

Biophys J. 2015 Jul 21;109(2):298-307. doi: 10.1016/j.bpj.2015.06.010.

26.

Investigation of epothilone B-induced cell death mechanisms in human epithelial cancer cells -in consideration of combined treatment with ionizing radiation.

Baumgart T, Kriesen S, Neels O, Hildebrandt G, Manda K.

Cancer Invest. 2015 Jul;33(6):213-24. doi: 10.3109/07357907.2015.1020115. Epub 2015 Apr 28.

PMID:
25919223
27.

Biophysics of α-synuclein induced membrane remodelling.

Shi Z, Sachs JN, Rhoades E, Baumgart T.

Phys Chem Chem Phys. 2015 Jun 28;17(24):15561-8. doi: 10.1039/c4cp05883f. Epub 2015 Feb 10.

28.

Membrane tension and peripheral protein density mediate membrane shape transitions.

Shi Z, Baumgart T.

Nat Commun. 2015 Jan 8;6:5974. doi: 10.1038/ncomms6974.

29.

Membrane morphology is actively transformed by covalent binding of the protein Atg8 to PE-lipids.

Knorr RL, Nakatogawa H, Ohsumi Y, Lipowsky R, Baumgart T, Dimova R.

PLoS One. 2014 Dec 18;9(12):e115357. doi: 10.1371/journal.pone.0115357. eCollection 2014.

30.

BIN1 membrane curvature sensing and generation show autoinhibition regulated by downstream ligands and PI(4,5)P2.

Wu T, Baumgart T.

Biochemistry. 2014 Nov 25;53(46):7297-309. doi: 10.1021/bi501082r. Epub 2014 Nov 14.

31.

Coupling between endocytosis and sphingosine kinase 1 recruitment.

Shen H, Giordano F, Wu Y, Chan J, Zhu C, Milosevic I, Wu X, Yao K, Chen B, Baumgart T, Sieburth D, De Camilli P.

Nat Cell Biol. 2014 Jul;16(7):652-62. doi: 10.1038/ncb2987. Epub 2014 Jun 15.

32.

Mutations in BIN1 associated with centronuclear myopathy disrupt membrane remodeling by affecting protein density and oligomerization.

Wu T, Shi Z, Baumgart T.

PLoS One. 2014 Apr 22;9(4):e93060. doi: 10.1371/journal.pone.0093060. eCollection 2014.

33.

Intradimer/Intermolecular interactions suggest autoinhibition mechanism in endophilin A1.

Chen Z, Chang K, Capraro BR, Zhu C, Hsu CJ, Baumgart T.

J Am Chem Soc. 2014 Mar 26;136(12):4557-64. doi: 10.1021/ja411607b. Epub 2014 Mar 13.

34.

Dynamics and instabilities of lipid bilayer membrane shapes.

Shi Z, Baumgart T.

Adv Colloid Interface Sci. 2014 Jun;208:76-88. doi: 10.1016/j.cis.2014.01.004. Epub 2014 Jan 25. Review.

35.

Exploiting imperfections in the bulk to direct assembly of surface colloids.

Cavallaro M Jr, Gharbi MA, Beller DA, Čopar S, Shi Z, Baumgart T, Yang S, Kamien RD, Stebe KJ.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18804-8. doi: 10.1073/pnas.1313551110. Epub 2013 Nov 4.

36.

C5a receptor (CD88) blockade protects against MPO-ANCA GN.

Xiao H, Dairaghi DJ, Powers JP, Ertl LS, Baumgart T, Wang Y, Seitz LC, Penfold ME, Gan L, Hu P, Lu B, Gerard NP, Gerard C, Schall TJ, Jaen JC, Falk RJ, Jennette JC.

J Am Soc Nephrol. 2014 Feb;25(2):225-31. doi: 10.1681/ASN.2013020143. Epub 2013 Oct 31.

37.

CCR2 antagonist CCX140-B provides renal and glycemic benefits in diabetic transgenic human CCR2 knockin mice.

Sullivan T, Miao Z, Dairaghi DJ, Krasinski A, Wang Y, Zhao BN, Baumgart T, Ertl LS, Pennell A, Seitz L, Powers J, Zhao R, Ungashe S, Wei Z, Boring L, Tsou CL, Charo I, Berahovich RD, Schall TJ, Jaen JC.

Am J Physiol Renal Physiol. 2013 Nov 1;305(9):F1288-97. doi: 10.1152/ajprenal.00316.2013. Epub 2013 Aug 28.

38.

Experimental evidence for the use of CCR2 antagonists in the treatment of type 2 diabetes.

Sullivan TJ, Miao Z, Zhao BN, Ertl LS, Wang Y, Krasinski A, Walters MJ, Powers JP, Dairaghi DJ, Baumgart T, Seitz LC, Berahovich RD, Schall TJ, Jaen JC.

Metabolism. 2013 Nov;62(11):1623-32. doi: 10.1016/j.metabol.2013.06.008. Epub 2013 Aug 15.

PMID:
23953944
39.

Exo70 generates membrane curvature for morphogenesis and cell migration.

Zhao Y, Liu J, Yang C, Capraro BR, Baumgart T, Bradley RP, Ramakrishnan N, Xu X, Radhakrishnan R, Svitkina T, Guo W.

Dev Cell. 2013 Aug 12;26(3):266-78. doi: 10.1016/j.devcel.2013.07.007.

40.

Measuring interactions between polydimethylsiloxane and serum proteins at the air-water interface.

Liao Z, Hsieh WT, Baumgart T, Dmochowski IJ.

Langmuir. 2013 Jul 30;29(30):9420-7. doi: 10.1021/la401619s. Epub 2013 Jul 15.

PMID:
23819833
41.

Kinetics of endophilin N-BAR domain dimerization and membrane interactions.

Capraro BR, Shi Z, Wu T, Chen Z, Dunn JM, Rhoades E, Baumgart T.

J Biol Chem. 2013 May 3;288(18):12533-43. doi: 10.1074/jbc.M112.435511. Epub 2013 Mar 12.

42.

Divide and adhere.

Baumgart T.

Biophys J. 2013 Feb 19;104(4):744-5. doi: 10.1016/j.bpj.2013.01.004. No abstract available.

43.

Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function.

May RM, Okumura M, Hsu CJ, Bassiri H, Yang E, Rak G, Mace EM, Philip NH, Zhang W, Baumgart T, Orange JS, Nichols KE, Kambayashi T.

Blood. 2013 Apr 18;121(16):3135-46. doi: 10.1182/blood-2012-12-474361. Epub 2013 Feb 13.

44.

Dynamic domains in polymersomes: mixtures of polyanionic and neutral diblocks respond more rapidly to changes in calcium than to pH.

Spinler K, Tian A, Christian DA, Pantano DA, Baumgart T, Discher DE.

Langmuir. 2013 Jun 18;29(24):7499-508. doi: 10.1021/la304602e. Epub 2013 Feb 11.

45.

Curvature sorting of proteins on a cylindrical lipid membrane tether connected to a reservoir.

Singh P, Mahata P, Baumgart T, Das SL.

Phys Rev E Stat Nonlin Soft Matter Phys. 2012 May;85(5 Pt 1):051906. Epub 2012 May 14.

46.

Lipid sorting by ceramide structure from plasma membrane to ER for the cholera toxin receptor ganglioside GM1.

Chinnapen DJ, Hsieh WT, te Welscher YM, Saslowsky DE, Kaoutzani L, Brandsma E, D'Auria L, Park H, Wagner JS, Drake KR, Kang M, Benjamin T, Ullman MD, Costello CE, Kenworthy AK, Baumgart T, Massol RH, Lencer WI.

Dev Cell. 2012 Sep 11;23(3):573-86. doi: 10.1016/j.devcel.2012.08.002.

47.
48.

Curvature sorting of peripheral proteins on solid-supported wavy membranes.

Hsieh WT, Hsu CJ, Capraro BR, Wu T, Chen CM, Yang S, Baumgart T.

Langmuir. 2012 Sep 4;28(35):12838-43. doi: 10.1021/la302205b. Epub 2012 Aug 23.

49.

Nonlinear sorting, curvature generation, and crowding of endophilin N-BAR on tubular membranes.

Zhu C, Das SL, Baumgart T.

Biophys J. 2012 Apr 18;102(8):1837-45. doi: 10.1016/j.bpj.2012.03.039.

50.

Elucidating membrane structure and protein behavior using giant plasma membrane vesicles.

Sezgin E, Kaiser HJ, Baumgart T, Schwille P, Simons K, Levental I.

Nat Protoc. 2012 May 3;7(6):1042-51. doi: 10.1038/nprot.2012.059.

PMID:
22555243

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