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Items: 1 to 50 of 255

1.

Metabolites of the ring-substituted stimulants MDMA, methylone and MDPV differentially affect human monoaminergic systems.

Luethi D, Kolaczynska KE, Walter M, Suzuki M, Rice KC, Blough BE, Hoener MC, Baumann MH, Liechti ME.

J Psychopharmacol. 2019 Jul;33(7):831-841. doi: 10.1177/0269881119844185. Epub 2019 Apr 30.

PMID:
31038382
2.

Evidence for nonlinear accumulation of the ultrapotent fentanyl analog, carfentanil, after systemic administration to male rats.

Bergh MS, Bogen IL, Garibay N, Baumann MH.

Neuropharmacology. 2019 Apr 6:107596. doi: 10.1016/j.neuropharm.2019.04.002. [Epub ahead of print]

PMID:
30965021
3.

2-Aminoindan and its ring-substituted derivatives interact with plasma membrane monoamine transporters and α2-adrenergic receptors.

Halberstadt AL, Brandt SD, Walther D, Baumann MH.

Psychopharmacology (Berl). 2019 Mar;236(3):989-999. doi: 10.1007/s00213-019-05207-1. Epub 2019 Mar 23.

PMID:
30904940
4.

The Supplement Adulterant β-Methylphenethylamine Increases Blood Pressure by Acting at Peripheral Norepinephrine Transporters.

Schindler CW, Thorndike EB, Rice KC, Partilla JS, Baumann MH.

J Pharmacol Exp Ther. 2019 Jun;369(3):328-336. doi: 10.1124/jpet.118.255976. Epub 2019 Mar 21.

5.

Pharmacological Research as a Key Component in Mitigating the Opioid Overdose Crisis.

Baumann MH, Kopajtic TA, Madras BK.

Trends Pharmacol Sci. 2018 Dec;39(12):995-998. doi: 10.1016/j.tips.2018.09.006. Review.

PMID:
30454770
6.

Neuropharmacology of Synthetic Cathinones.

Baumann MH, Walters HM, Niello M, Sitte HH.

Handb Exp Pharmacol. 2018;252:113-142. doi: 10.1007/164_2018_178.

PMID:
30406443
7.

Systematic Structure-Activity Studies on Selected 2-, 3-, and 4-Monosubstituted Synthetic Methcathinone Analogs as Monoamine Transporter Releasing Agents.

Walther D, Shalabi AR, Baumann MH, Glennon RA.

ACS Chem Neurosci. 2019 Jan 16;10(1):740-745. doi: 10.1021/acschemneuro.8b00524. Epub 2018 Nov 7.

PMID:
30354055
8.

The synthetic cathinones, butylone and pentylone, are stimulants that act as dopamine transporter blockers but 5-HT transporter substrates.

Saha K, Li Y, Holy M, Lehner KR, Bukhari MO, Partilla JS, Sandtner W, Sitte HH, Baumann MH.

Psychopharmacology (Berl). 2019 Mar;236(3):953-962. doi: 10.1007/s00213-018-5075-5. Epub 2018 Oct 22.

PMID:
30345459
9.

The dopamine, serotonin and norepinephrine releasing activities of a series of methcathinone analogs in male rat brain synaptosomes.

Blough BE, Decker AM, Landavazo A, Namjoshi OA, Partilla JS, Baumann MH, Rothman RB.

Psychopharmacology (Berl). 2019 Mar;236(3):915-924. doi: 10.1007/s00213-018-5063-9. Epub 2018 Oct 20.

PMID:
30341459
10.

The abuse-related effects of pyrrolidine-containing cathinones are related to their potency and selectivity to inhibit the dopamine transporter.

Gannon BM, Baumann MH, Walther D, Jimenez-Morigosa C, Sulima A, Rice KC, Collins GT.

Neuropsychopharmacology. 2018 Nov;43(12):2399-2407. doi: 10.1038/s41386-018-0209-3. Epub 2018 Sep 10.

PMID:
30305739
11.

Pharmacodynamic Effects, Pharmacokinetics, and Metabolism of the Synthetic Cannabinoid AM-2201 in Male Rats.

Carlier J, Wohlfarth A, Salmeron BD, Scheidweiler KB, Huestis MA, Baumann MH.

J Pharmacol Exp Ther. 2018 Dec;367(3):543-550. doi: 10.1124/jpet.118.250530. Epub 2018 Sep 28.

12.

Analytical quantification, intoxication case series, and pharmacological mechanism of action for N-ethylnorpentylone (N-ethylpentylone or ephylone).

Costa JL, Cunha KF, Lanaro R, Cunha RL, Walther D, Baumann MH.

Drug Test Anal. 2019 Mar;11(3):461-471. doi: 10.1002/dta.2502. Epub 2018 Oct 21.

PMID:
30207090
13.

Effects of N-Alkyl-4-Methylamphetamine Optical Isomers on Plasma Membrane Monoamine Transporters and Abuse-Related Behavior.

Battisti UM, Sitta R, Harris A, Sakloth F, Walther D, Ruchala I, Negus SS, Baumann MH, Glennon RA, Eltit JM.

ACS Chem Neurosci. 2018 Jul 18;9(7):1829-1839. doi: 10.1021/acschemneuro.8b00138. Epub 2018 May 14.

14.

Synthesis, analytical characterization, and monoamine transporter activity of the new psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation from its ortho- and meta- positional isomers.

McLaughlin G, Baumann MH, Kavanagh PV, Morris N, Power JD, Dowling G, Twamley B, O'Brien J, Hessman G, Westphal F, Walther D, Brandt SD.

Drug Test Anal. 2018 Sep;10(9):1404-1416. doi: 10.1002/dta.2396. Epub 2018 May 23.

PMID:
29673128
15.

Repeated Exposure to the "Spice" Cannabinoid JWH-018 Induces Tolerance and Enhances Responsiveness to 5-HT1A Receptor Stimulation in Male Rats.

Elmore JS, Baumann MH.

Front Psychiatry. 2018 Feb 27;9:55. doi: 10.3389/fpsyt.2018.00055. eCollection 2018.

16.

Comparative neuropharmacology of N-(2-methoxybenzyl)-2,5-dimethoxyphenethylamine (NBOMe) hallucinogens and their 2C counterparts in male rats.

Elmore JS, Decker AM, Sulima A, Rice KC, Partilla JS, Blough BE, Baumann MH.

Neuropharmacology. 2018 Nov;142:240-250. doi: 10.1016/j.neuropharm.2018.02.033. Epub 2018 Mar 1.

PMID:
29501528
17.

Fentanyl-related designer drugs W-18 and W-15 lack appreciable opioid activity in vitro and in vivo.

Huang XP, Che T, Mangano TJ, Le Rouzic V, Pan YX, Majumdar S, Cameron MD, Baumann MH, Pasternak GW, Roth BL.

JCI Insight. 2017 Nov 16;2(22). pii: 97222. doi: 10.1172/jci.insight.97222. eCollection 2017 Nov 16.

18.

Novel Synthetic Opioids and Overdose Deaths: Tip of the Iceberg?

Baumann MH, Pasternak GW.

Neuropsychopharmacology. 2018 Jan;43(1):216-217. doi: 10.1038/npp.2017.211. No abstract available.

19.

Fluorinated phenmetrazine "legal highs" act as substrates for high-affinity monoamine transporters of the SLC6 family.

Mayer FP, Burchardt NV, Decker AM, Partilla JS, Li Y, McLaughlin G, Kavanagh PV, Sandtner W, Blough BE, Brandt SD, Baumann MH, Sitte HH.

Neuropharmacology. 2018 May 15;134(Pt A):149-157. doi: 10.1016/j.neuropharm.2017.10.006. Epub 2017 Oct 6.

20.

Trace amine-associated receptor 1 regulation of methamphetamine-induced neurotoxicity.

Miner NB, Elmore JS, Baumann MH, Phillips TJ, Janowsky A.

Neurotoxicology. 2017 Dec;63:57-69. doi: 10.1016/j.neuro.2017.09.006. Epub 2017 Sep 15.

21.

Synthetic cannabinoids found in "spice" products alter body temperature and cardiovascular parameters in conscious male rats.

Schindler CW, Gramling BR, Justinova Z, Thorndike EB, Baumann MH.

Drug Alcohol Depend. 2017 Oct 1;179:387-394. doi: 10.1016/j.drugalcdep.2017.07.029. Epub 2017 Aug 18.

22.

Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates.

Bhat S, Hasenhuetl PS, Kasture A, El-Kasaby A, Baumann MH, Blough BE, Sucic S, Sandtner W, Freissmuth M.

J Biol Chem. 2017 Oct 6;292(40):16773-16786. doi: 10.1074/jbc.M117.794081. Epub 2017 Aug 23.

23.

Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace.

Baumann MH, Majumdar S, Le Rouzic V, Hunkele A, Uprety R, Huang XP, Xu J, Roth BL, Pan YX, Pasternak GW.

Neuropharmacology. 2018 May 15;134(Pt A):101-107. doi: 10.1016/j.neuropharm.2017.08.016. Epub 2017 Aug 12.

24.

Impact of Novel Psychoactive Substances on Clinical and Forensic Toxicology and Global Public Health.

Huestis MA, Brandt SD, Rana S, Auwärter V, Baumann MH.

Clin Chem. 2017 Oct;63(10):1564-1569. doi: 10.1373/clinchem.2017.274662. Epub 2017 Jun 30. No abstract available.

25.

Misuse of Novel Synthetic Opioids: A Deadly New Trend.

Prekupec MP, Mansky PA, Baumann MH.

J Addict Med. 2017 Jul/Aug;11(4):256-265. doi: 10.1097/ADM.0000000000000324. Review.

26.

N-Alkylated Analogs of 4-Methylamphetamine (4-MA) Differentially Affect Monoamine Transporters and Abuse Liability.

Solis E Jr, Partilla JS, Sakloth F, Ruchala I, Schwienteck KL, De Felice LJ, Eltit JM, Glennon RA, Negus SS, Baumann MH.

Neuropsychopharmacology. 2017 Sep;42(10):1950-1961. doi: 10.1038/npp.2017.98. Epub 2017 May 22.

27.

Deconstructed Analogues of Bupropion Reveal Structural Requirements for Transporter Inhibition versus Substrate-Induced Neurotransmitter Release.

Shalabi AR, Walther D, Baumann MH, Glennon RA.

ACS Chem Neurosci. 2017 Jun 21;8(6):1397-1403. doi: 10.1021/acschemneuro.7b00055. Epub 2017 Feb 27.

PMID:
28220701
28.

Atypical dopamine efflux caused by 3,4-methylenedioxypyrovalerone (MDPV) via the human dopamine transporter.

Shekar A, Aguilar JI, Galli G, Cozzi NV, Brandt SD, Ruoho AE, Baumann MH, Matthies HJG, Galli A.

J Chem Neuroanat. 2017 Oct;83-84:69-74. doi: 10.1016/j.jchemneu.2017.01.004. Epub 2017 Feb 3.

29.

Analytical characterization and pharmacological evaluation of the new psychoactive substance 4-fluoromethylphenidate (4F-MPH) and differentiation between the (±)-threo and (±)-erythro diastereomers.

McLaughlin G, Morris N, Kavanagh PV, Power JD, Dowling G, Twamley B, O'Brien J, Hessman G, Murphy B, Walther D, Partilla JS, Baumann MH, Brandt SD.

Drug Test Anal. 2017 Mar;9(3):347-357. doi: 10.1002/dta.2167. Epub 2017 Mar 7.

30.

Neuropharmacology of 3,4-Methylenedioxypyrovalerone (MDPV), Its Metabolites, and Related Analogs.

Baumann MH, Bukhari MO, Lehner KR, Anizan S, Rice KC, Concheiro M, Huestis MA.

Curr Top Behav Neurosci. 2017;32:93-117. doi: 10.1007/7854_2016_53. Review.

31.

Pharmacokinetic Profiles and Pharmacodynamic Effects for Methylone and Its Metabolites in Rats.

Elmore JS, Dillon-Carter O, Partilla JS, Ellefsen KN, Concheiro M, Suzuki M, Rice KC, Huestis MA, Baumann MH.

Neuropsychopharmacology. 2017 Feb;42(3):649-660. doi: 10.1038/npp.2016.213. Epub 2016 Sep 23.

32.

Enduring Loss of Serotonergic Control of Orbitofrontal Cortex Function Following Contingent and Noncontingent Cocaine Exposure.

Wright AM, Zapata A, Baumann MH, Elmore JS, Hoffman AF, Lupica CR.

Cereb Cortex. 2017 Dec 1;27(12):5463-5476. doi: 10.1093/cercor/bhw312.

33.

Pharmacological mechanisms underlying the cardiovascular effects of the "bath salt" constituent 3,4-methylenedioxypyrovalerone (MDPV).

Schindler CW, Thorndike EB, Suzuki M, Rice KC, Baumann MH.

Br J Pharmacol. 2016 Dec;173(24):3492-3501. doi: 10.1111/bph.13640. Epub 2016 Nov 16.

34.

Cadherin 13: human cis-regulation and selectively-altered addiction phenotypes and cerebral cortical dopamine in knockout mice.

Drgonova J, Walther D, Hartstein GL, Bukhari MO, Baumann MH, Katz J, Hall FS, Arnold ER, Flax S, Riley A, Rivero-Martin O, Lesch KP, Troncoso J, Ranscht B, Uhl GR.

Mol Med. 2016 Oct;22:537-547. doi: 10.2119/molmed.2015.00170. Epub 2016 Aug 18.

35.

Synthesis, characterization and monoamine transporter activity of the new psychoactive substance mexedrone and its N-methoxy positional isomer, N-methoxymephedrone.

McLaughlin G, Morris N, Kavanagh PV, Power JD, Dowling G, Twamley B, O'Brien J, Talbot B, Walther D, Partilla JS, Baumann MH, Brandt SD.

Drug Test Anal. 2017 Mar;9(3):358-368. doi: 10.1002/dta.2053. Epub 2016 Sep 21.

36.

The Changing Face of Recreational Drug Use.

Baumann MH.

Cerebrum. 2016 Jan 1;2016. pii: cer-01-16. eCollection 2016 Jan-Feb.

37.

Phase I metabolites of mephedrone display biological activity as substrates at monoamine transporters.

Mayer FP, Wimmer L, Dillon-Carter O, Partilla JS, Burchardt NV, Mihovilovic MD, Baumann MH, Sitte HH.

Br J Pharmacol. 2016 Sep;173(17):2657-68. doi: 10.1111/bph.13547. Epub 2016 Jul 31.

38.

Quantification of [1-(5-fluoropentyl)-1H-indol-3-yl](naphthalene-1-yl)methanone (AM-2201) and 13 metabolites in human and rat plasma by liquid chromatography-tandem mass spectrometry.

Carlier J, Scheidweiler KB, Wohlfarth A, Salmeron BD, Baumann MH, Huestis MA.

J Chromatogr A. 2016 Jun 17;1451:97-106. doi: 10.1016/j.chroma.2016.05.020. Epub 2016 May 6.

39.

Abuse-related neurochemical and behavioral effects of cathinone and 4-methylcathinone stereoisomers in rats.

Hutsell BA, Baumann MH, Partilla JS, Banks ML, Vekariya R, Glennon RA, Negus SS.

Eur Neuropsychopharmacol. 2016 Feb;26(2):288-297. doi: 10.1016/j.euroneuro.2015.12.010. Epub 2015 Dec 11.

40.

Disruption of hippocampal synaptic transmission and long-term potentiation by psychoactive synthetic cannabinoid 'Spice' compounds: comparison with Δ9 -tetrahydrocannabinol.

Hoffman AF, Lycas MD, Kaczmarzyk JR, Spivak CE, Baumann MH, Lupica CR.

Addict Biol. 2017 Mar;22(2):390-399. doi: 10.1111/adb.12334. Epub 2016 Jan 5.

41.

Binding Mode Selection Determines the Action of Ecstasy Homologs at Monoamine Transporters.

Sandtner W, Stockner T, Hasenhuetl PS, Partilla JS, Seddik A, Zhang YW, Cao J, Holy M, Steinkellner T, Rudnick G, Baumann MH, Ecker GF, Newman AH, Sitte HH.

Mol Pharmacol. 2016 Jan;89(1):165-75. doi: 10.1124/mol.115.101394. Epub 2015 Oct 30.

42.

The new psychoactive substances 5-(2-aminopropyl)indole (5-IT) and 6-(2-aminopropyl)indole (6-IT) interact with monoamine transporters in brain tissue.

Marusich JA, Antonazzo KR, Blough BE, Brandt SD, Kavanagh PV, Partilla JS, Baumann MH.

Neuropharmacology. 2016 Feb;101:68-75. doi: 10.1016/j.neuropharm.2015.09.004. Epub 2015 Sep 8.

43.

Reinforcing and neurochemical effects of the "bath salts" constituents 3,4-methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxy-N-methylcathinone (methylone) in male rats.

Schindler CW, Thorndike EB, Goldberg SR, Lehner KR, Cozzi NV, Brandt SD, Baumann MH.

Psychopharmacology (Berl). 2016 May;233(10):1981-90. doi: 10.1007/s00213-015-4057-0. Epub 2015 Aug 29.

44.

Abuse of New Psychoactive Substances: Threats and Solutions.

Baumann MH, Volkow ND.

Neuropsychopharmacology. 2016 Feb;41(3):663-5. doi: 10.1038/npp.2015.260. Epub 2015 Aug 25. No abstract available.

45.
46.

Structural Modification of the Designer Stimulant α-Pyrrolidinovalerophenone (α-PVP) Influences Potency at Dopamine Transporters.

Kolanos R, Sakloth F, Jain AD, Partilla JS, Baumann MH, Glennon RA.

ACS Chem Neurosci. 2015 Oct 21;6(10):1726-31. doi: 10.1021/acschemneuro.5b00160. Epub 2015 Aug 11.

47.

Quantitative analysis of PPT1 interactome in human neuroblastoma cells.

Scifo E, Szwajda A, Soliymani R, Pezzini F, Bianchi M, Dapkunas A, Dębski J, Uusi-Rauva K, Dadlez M, Gingras AC, Tyynelä J, Simonati A, Jalanko A, Baumann MH, Lalowski M.

Data Brief. 2015 Jun 12;4:207-16. doi: 10.1016/j.dib.2015.05.016. eCollection 2015 Sep.

48.

Clinically Relevant Pharmacological Strategies That Reverse MDMA-Induced Brain Hyperthermia Potentiated by Social Interaction.

Kiyatkin EA, Ren S, Wakabayashi KT, Baumann MH, Shaham Y.

Neuropsychopharmacology. 2016 Jan;41(2):549-59. doi: 10.1038/npp.2015.182. Epub 2015 Jun 24.

49.

Proteomic analysis of the palmitoyl protein thioesterase 1 interactome in SH-SY5Y human neuroblastoma cells.

Scifo E, Szwajda A, Soliymani R, Pezzini F, Bianchi M, Dapkunas A, Dębski J, Uusi-Rauva K, Dadlez M, Gingras AC, Tyynelä J, Simonati A, Jalanko A, Baumann MH, Lalowski M.

J Proteomics. 2015 Jun 18;123:42-53. doi: 10.1016/j.jprot.2015.03.038. Epub 2015 Apr 10.

PMID:
25865307
50.

Studies of the biogenic amine transporters 15. Identification of novel allosteric dopamine transporter ligands with nanomolar potency.

Rothman RB, Ananthan S, Partilla JS, Saini SK, Moukha-Chafiq O, Pathak V, Baumann MH.

J Pharmacol Exp Ther. 2015 Jun;353(3):529-38. doi: 10.1124/jpet.114.222299. Epub 2015 Mar 18.

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