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Baum BJ.

J Natl Cancer Inst Monogr. 2019 Aug 1;2019(53). pii: lgz001. doi: 10.1093/jncimonographs/lgz001. No abstract available.


Using salivary glands to treat serious systemic diseases-Examples of new roles for oral medicine in the healthcare team?

Baum BJ.

Oral Dis. 2019 Jan;25(1):3-5. doi: 10.1111/odi.12848. Epub 2018 Apr 10. No abstract available.



Baum BJ.

Oral Dis. 2018 Mar;24(1-2):3-4. doi: 10.1111/odi.12787. No abstract available.


Professor Crispian Scully.

Baum BJ.

Oral Dis. 2017 May;23(4):403. doi: 10.1111/odi.12670. No abstract available.


Effect of Tempol on the prevention of irradiation-induced mucositis in miniature pigs.

Hu L, Wang Y, Cotrim AP, Zhu Z, Gao R, Zheng C, Goldsmith CM, Jin L, Zhang C, Mitchell JB, Baum BJ, Wang S.

Oral Dis. 2017 Sep;23(6):801-808. doi: 10.1111/odi.12667. Epub 2017 Apr 27.


Late responses to adenoviral-mediated transfer of the aquaporin-1 gene for radiation-induced salivary hypofunction.

Alevizos I, Zheng C, Cotrim AP, Liu S, McCullagh L, Billings ME, Goldsmith CM, Tandon M, Helmerhorst EJ, Catalán MA, Danielides SJ, Perez P, Nikolov NP, Chiorini JA, Melvin JE, Oppenheim FG, Illei GG, Baum BJ.

Gene Ther. 2017 Mar;24(3):176-186. doi: 10.1038/gt.2016.87. Epub 2016 Dec 20.


Gene Therapy of Salivary Diseases.

Baum BJ, Afione S, Chiorini JA, Cotrim AP, Goldsmith CM, Zheng C.

Methods Mol Biol. 2017;1537:107-123.


Immune reactivity after adenoviral-mediated aquaporin-1 cDNA transfer to human parotid glands.

Alevizos I, Zheng C, Cotrim AP, Goldsmith CM, McCullagh L, Berkowitz T, Strobl SL, Malyguine A, Kopp WC, Chiorini JA, Nikolov NP, Neely M, Illei GG, Baum BJ.

Oral Dis. 2017 Apr;23(3):337-346. doi: 10.1111/odi.12614. Epub 2017 Feb 8.


Outcomes From the NIH Clinical Research Training Program: A Mentored Research Experience to Enhance Career Development of Clinician-Scientists.

Ognibene FP, Gallin JI, Baum BJ, Wyatt RG, Gottesman MM.

Acad Med. 2016 Dec;91(12):1684-1690. doi: 10.1097/ACM.0000000000001245.


Adenovirus-mediated hAQP1 expression in irradiated mouse salivary glands causes recovery of saliva secretion by enhancing acinar cell volume decrease.

Teos LY, Zheng CY, Liu X, Swaim WD, Goldsmith CM, Cotrim AP, Baum BJ, Ambudkar IS.

Gene Ther. 2016 Jul;23(7):572-9. doi: 10.1038/gt.2016.29. Epub 2016 Mar 11.


Radiation-Induced Loss of Salivary Gland Function Is Driven by Cellular Senescence and Prevented by IL6 Modulation.

Marmary Y, Adar R, Gaska S, Wygoda A, Maly A, Cohen J, Eliashar R, Mizrachi L, Orfaig-Geva C, Baum BJ, Rose-John S, Galun E, Axelrod JH.

Cancer Res. 2016 Mar 1;76(5):1170-80. doi: 10.1158/0008-5472.CAN-15-1671. Epub 2016 Jan 12. Erratum in: Cancer Res. 2016 May 1;76(9):2846.


Radiation-induced salivary hypofunction may become a thing of the past.

Baum BJ.

Oral Dis. 2016 Mar;22(2):81-4. doi: 10.1111/odi.12388. Epub 2016 Jan 11. No abstract available.


Alfred Traxler Baum, 1922-2015.

Baum GM, Baum BJ.

Am J Orthod Dentofacial Orthop. 2015 Jul;148(1):192. No abstract available.


Persistence of hAQP1 expression in human salivary gland cells following AdhAQP1 transduction is associated with a lack of methylation of hCMV promoter.

Zheng C, Baum BJ, Liu X, Goldsmith CM, Perez P, Jang SI, Cotrim AP, McCullagh L, Ambudkar IS, Alevizos I.

Gene Ther. 2015 Sep;22(9):758-66. doi: 10.1038/gt.2015.55. Epub 2015 Jul 16.


Advances in salivary gland gene therapy - oral and systemic implications.

Baum BJ, Alevizos I, Chiorini JA, Cotrim AP, Zheng C.

Expert Opin Biol Ther. 2015;15(10):1443-54. doi: 10.1517/14712598.2015.1064894. Epub 2015 Jul 6. Review.


Training specialists in oral medicine.

Baum BJ, Scully C.

Oral Dis. 2015 Sep;21(6):681-4. doi: 10.1111/odi.12351. Epub 2015 Jun 30. No abstract available.


Gene therapy in dentistry: present and future.

Baum BJ.

Am J Dent. 2014 Dec;27(6):335-40. Review.


AdLTR2EF1α-FGF2-mediated prevention of fractionated irradiation-induced salivary hypofunction in swine.

Guo L, Gao R, Xu J, Jin L, Cotrim AP, Yan X, Zheng C, Goldsmith CM, Shan Z, Hai B, Zhou J, Zhang C, Baum BJ, Wang S.

Gene Ther. 2014 Oct;21(10):866-73. doi: 10.1038/gt.2014.63. Epub 2014 Jul 17.


Integration of the hybrid adenoretroviral vector AdLTR-luc involves both MoMLV elements flanking the transgene.

Zheng C, Baum BJ.

Int J Med Sci. 2014 Jun 1;11(8):803-9. doi: 10.7150/ijms.9084. eCollection 2014.


All human EF1α promoters are not equal: markedly affect gene expression in constructs from different sources.

Zheng C, Baum BJ.

Int J Med Sci. 2014 Mar 7;11(5):404-8. doi: 10.7150/ijms.8033. eCollection 2014.


Gene therapy.

Baum BJ.

Oral Dis. 2014 Mar;20(2):115-8. doi: 10.1111/odi.12211. Epub 2013 Dec 26.


Toward gene therapy for growth hormone deficiency via salivary gland expression of growth hormone.

Racz GZ, Zheng C, Goldsmith CM, Baum BJ, Cawley NX.

Oral Dis. 2015 Mar;21(2):149-55. doi: 10.1111/odi.12217. Epub 2014 Jan 13.


Expression and secretion of human proinsulin-B10 from mouse salivary glands: implications for the treatment of type I diabetes mellitus.

Rowzee AM, Perez-Riveros PJ, Zheng C, Krygowski S, Baum BJ, Cawley NX.

PLoS One. 2013;8(3):e59222. doi: 10.1371/journal.pone.0059222. Epub 2013 Mar 15.


Recovery of radiation-induced dry eye and corneal damage by pretreatment with adenoviral vector-mediated transfer of erythropoietin to the salivary glands in mice.

Rocha EM, Cotrim AP, Zheng C, Riveros PP, Baum BJ, Chiorini JA.

Hum Gene Ther. 2013 Apr;24(4):417-23. doi: 10.1089/hum.2012.111.


Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction.

Baum BJ, Alevizos I, Zheng C, Cotrim AP, Liu S, McCullagh L, Goldsmith CM, Burbelo PD, Citrin DE, Mitchell JB, Nottingham LK, Rudy SF, Van Waes C, Whatley MA, Brahim JS, Chiorini JA, Danielides S, Turner RJ, Patronas NJ, Chen CC, Nikolov NP, Illei GG.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19403-7. doi: 10.1073/pnas.1210662109. Epub 2012 Nov 5.


Distribution of Y-receptors in murine lingual epithelia.

Hurtado MD, Acosta A, Riveros PP, Baum BJ, Ukhanov K, Brown AR, Dotson CD, Herzog H, Zolotukhin S.

PLoS One. 2012;7(9):e46358. doi: 10.1371/journal.pone.0046358. Epub 2012 Sep 26.


A novel hybrid adenoretroviral vector with more extensive E3 deletion extends transgene expression in submandibular glands.

Zheng C, Cotrim AP, Nikolov N, Mineshiba F, Swaim W, Baum BJ.

Hum Gene Ther Methods. 2012 Jun;23(3):169-81. doi: 10.1089/hgtb.2011.175. Epub 2012 Jul 20.


Including the p53 ELAV-like protein-binding site in vector cassettes enhances transgene expression in rat submandibular gland.

Zheng C, Baum BJ.

Oral Dis. 2012 Jul;18(5):477-84. doi: 10.1111/j.1601-0825.2011.01895.x. Epub 2012 Jan 18.


Pharmacological protection from radiation ± cisplatin-induced oral mucositis.

Cotrim AP, Yoshikawa M, Sunshine AN, Zheng C, Sowers AL, Thetford AD, Cook JA, Mitchell JB, Baum BJ.

Int J Radiat Oncol Biol Phys. 2012 Jul 15;83(4):1284-90. doi: 10.1016/j.ijrobp.2011.09.026. Epub 2011 Dec 22.


Salivary PYY: a putative bypass to satiety.

Acosta A, Hurtado MD, Gorbatyuk O, La Sala M, Duncan D, Aslanidi G, Campbell-Thompson M, Zhang L, Herzog H, Voutetakis A, Baum BJ, Zolotukhin S.

PLoS One. 2011;6(10):e26137. doi: 10.1371/journal.pone.0026137. Epub 2011 Oct 10.


Scientific frontiers: emerging technologies for salivary diagnostics.

Baum BJ, Yates JR 3rd, Srivastava S, Wong DT, Melvin JE.

Adv Dent Res. 2011 Oct;23(4):360-8. doi: 10.1177/0022034511420433.


Gene delivery in salivary glands: from the bench to the clinic.

Samuni Y, Baum BJ.

Biochim Biophys Acta. 2011 Nov;1812(11):1515-21. doi: 10.1016/j.bbadis.2011.06.014. Epub 2011 Jul 6. Review.


Assessment of the safety and biodistribution of a regulated AAV2 gene transfer vector after delivery to murine submandibular glands.

Zheng C, Voutetakis A, Goldstein B, Afione S, Rivera VM, Clackson T, Wenk ML, Boyle M, Nyska A, Chiorini JA, Vallant M, Irwin RD, Baum BJ.

Toxicol Sci. 2011 Sep;123(1):247-55. doi: 10.1093/toxsci/kfr144. Epub 2011 May 30.


Prevention of radiation-induced salivary hypofunction following hKGF gene delivery to murine submandibular glands.

Zheng C, Cotrim AP, Rowzee A, Swaim W, Sowers A, Mitchell JB, Baum BJ.

Clin Cancer Res. 2011 May 1;17(9):2842-51. doi: 10.1158/1078-0432.CCR-10-2982. Epub 2011 Mar 2.


Transgenic α-1-antitrypsin secreted into the bloodstream from salivary glands is biologically active.

Perez P, Adriaansen J, Goldsmith CM, Zheng C, Baum BJ.

Oral Dis. 2011 Jul;17(5):476-83. doi: 10.1111/j.1601-0825.2010.01775.x. Epub 2010 Dec 2.


Human parathyroid hormone is secreted primarily into the bloodstream after rat parotid gland gene transfer.

Adriaansen J, Perez P, Zheng C, Collins MT, Baum BJ.

Hum Gene Ther. 2011 Jan;22(1):84-92. doi: 10.1089/hum.2010.097. Epub 2011 Jan 3.


Clinical management of salivary gland hypofunction and xerostomia in head-and-neck cancer patients: successes and barriers.

Vissink A, Mitchell JB, Baum BJ, Limesand KH, Jensen SB, Fox PC, Elting LS, Langendijk JA, Coppes RP, Reyland ME.

Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):983-91. doi: 10.1016/j.ijrobp.2010.06.052. Review.


Microchimerism in salivary glands after blood- and marrow-derived stem cell transplantation.

Tran SD, Redman RS, Barrett AJ, Pavletic SZ, Key S, Liu Y, Carpenter A, Nguyen HM, Sumita Y, Baum BJ, Pillemer SR, Mezey E.

Biol Blood Marrow Transplant. 2011 Mar;17(3):429-33. doi: 10.1016/j.bbmt.2010.09.021. Epub 2010 Dec 4.


AAV2-mediated transfer of the human aquaporin-1 cDNA restores fluid secretion from irradiated miniature pig parotid glands.

Gao R, Yan X, Zheng C, Goldsmith CM, Afione S, Hai B, Xu J, Zhou J, Zhang C, Chiorini JA, Baum BJ, Wang S.

Gene Ther. 2011 Jan;18(1):38-42. doi: 10.1038/gt.2010.128. Epub 2010 Sep 30.


Effect of irradiation on microvascular endothelial cells of parotid glands in the miniature pig.

Xu J, Yan X, Gao R, Mao L, Cotrim AP, Zheng C, Zhang C, Baum BJ, Wang S.

Int J Radiat Oncol Biol Phys. 2010 Nov 1;78(3):897-903. doi: 10.1016/j.ijrobp.2010.05.048. Epub 2010 Sep 9.


Gene therapy of salivary diseases.

Baum BJ, Adriaansen J, Cotrim AP, Goldsmith CM, Perez P, Qi S, Rowzee AM, Zheng C.

Methods Mol Biol. 2010;666:3-20. doi: 10.1007/978-1-60761-820-1_1.


Convenient and reproducible in vivo gene transfer to mouse parotid glands.

Zheng C, Shinomiya T, Goldsmith CM, Di Pasquale G, Baum BJ.

Oral Dis. 2011 Jan;17(1):77-82. doi: 10.1111/j.1601-0825.2010.01707.x.


Systemic delivery of bioactive glucagon-like peptide 1 after adenoviral-mediated gene transfer in the murine salivary gland.

Voutetakis A, Cotrim AP, Rowzee A, Zheng C, Rathod T, Yanik T, Loh YP, Baum BJ, Cawley NX.

Endocrinology. 2010 Sep;151(9):4566-72. doi: 10.1210/en.2010-0193. Epub 2010 Jul 7.


Radioprotectors and mitigators of radiation-induced normal tissue injury.

Citrin D, Cotrim AP, Hyodo F, Baum BJ, Krishna MC, Mitchell JB.

Oncologist. 2010;15(4):360-71. doi: 10.1634/theoncologist.2009-S104. Review.


Evaluation of a rapamycin-regulated serotype 2 adeno-associated viral vector in macaque parotid glands.

Zheng C, Voutetakis A, Metzger M, Afione S, Cotrim AP, Eckhaus MA, Rivera VM, Clackson T, Chiorini JA, Donahue RE, Dunbar CE, Baum BJ.

Oral Dis. 2010 Apr;16(3):269-77. doi: 10.1111/j.1601-0825.2009.01631.x.


Salivary epithelial cells: an unassuming target site for gene therapeutics.

Perez P, Rowzee AM, Zheng C, Adriaansen J, Baum BJ.

Int J Biochem Cell Biol. 2010 Jun;42(6):773-7. doi: 10.1016/j.biocel.2010.02.012. Epub 2010 Feb 26. Review.


Conditional overexpression of TGF-beta1 disrupts mouse salivary gland development and function.

Hall BE, Zheng C, Swaim WD, Cho A, Nagineni CN, Eckhaus MA, Flanders KC, Ambudkar IS, Baum BJ, Kulkarni AB.

Lab Invest. 2010 Apr;90(4):543-55. doi: 10.1038/labinvest.2010.5. Epub 2010 Feb 8.


Production and sorting of transgenic, modified human parathyroid hormone in vivo in rat salivary glands.

Adriaansen J, Zheng C, Perez P, Baum BJ.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):768-72. doi: 10.1016/j.bbrc.2009.11.135. Epub 2009 Nov 26.


Transient detection of E1-containing adenovirus in saliva after the delivery of a first-generation adenoviral vector to human parotid gland.

Zheng C, Nikolov NP, Alevizos I, Cotrim AP, Liu S, McCullagh L, Chiorini JA, Illei GG, Baum BJ.

J Gene Med. 2010 Jan;12(1):3-10. doi: 10.1002/jgm.1416.


Development of a gene transfer-based treatment for radiation-induced salivary hypofunction.

Baum BJ, Zheng C, Alevizos I, Cotrim AP, Liu S, McCullagh L, Goldsmith CM, McDermott N, Chiorini JA, Nikolov NP, Illei GG.

Oral Oncol. 2010 Jan;46(1):4-8. doi: 10.1016/j.oraloncology.2009.09.004. Epub 2009 Nov 4. Review.

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