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Items: 25


Regulatory T-cell Genes Drive Altered Immune Microenvironment in Adult Solid Cancers and Allow for Immune Contextual Patient Subtyping.

Brouwer-Visser J, Cheng WY, Bauer-Mehren A, Maisel D, Lechner K, Andersson E, Dudley JT, Milletti F.

Cancer Epidemiol Biomarkers Prev. 2018 Jan;27(1):103-112. doi: 10.1158/1055-9965.EPI-17-0461. Epub 2017 Nov 13.


Proton Pump Inhibitor Usage and the Risk of Myocardial Infarction in the General Population.

Shah NH, LePendu P, Bauer-Mehren A, Ghebremariam YT, Iyer SV, Marcus J, Nead KT, Cooke JP, Leeper NJ.

PLoS One. 2015 Jun 10;10(6):e0124653. doi: 10.1371/journal.pone.0124653. eCollection 2015.


DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes.

Piñero J, Queralt-Rosinach N, Bravo À, Deu-Pons J, Bauer-Mehren A, Baron M, Sanz F, Furlong LI.

Database (Oxford). 2015 Apr 15;2015:bav028. doi: 10.1093/database/bav028. Print 2015.


Functional evaluation of out-of-the-box text-mining tools for data-mining tasks.

Jung K, LePendu P, Iyer S, Bauer-Mehren A, Percha B, Shah NH.

J Am Med Inform Assoc. 2015 Jan;22(1):121-31. doi: 10.1136/amiajnl-2014-002902. Epub 2014 Oct 21.


Gathering and exploring scientific knowledge in pharmacovigilance.

Lopes P, Nunes T, Campos D, Furlong LI, Bauer-Mehren A, Sanz F, Carrascosa MC, Mestres J, Kors J, Singh B, van Mulligen E, Van der Lei J, Diallo G, Avillach P, Ahlberg E, Boyer S, Diaz C, Oliveira JL.

PLoS One. 2013 Dec 11;8(12):e83016. doi: 10.1371/journal.pone.0083016. eCollection 2013.


Pharmacovigilance using Clinical Text.

Lependu P, Iyer SV, Bauer-Mehren A, Harpaz R, Ghebremariam YT, Cooke JP, Shah NH.

AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:109. eCollection 2013.


Learning signals of adverse drug-drug interactions from the unstructured text of electronic health records.

Iyer SV, Lependu P, Harpaz R, Bauer-Mehren A, Shah NH.

AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:83-7. eCollection 2013.


Learning signals of adverse drug-drug interactions from the unstructured text of electronic health records.

Iyer SV, Lependu P, Harpaz R, Bauer-Mehren A, Shah NH.

AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:98. eCollection 2013.


Network analysis of unstructured EHR data for clinical research.

Bauer-Mehren A, Lependu P, Iyer SV, Harpaz R, Leeper NJ, Shah NH.

AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:14-8. eCollection 2013.


Profiling risk factors for chronic uveitis in juvenile idiopathic arthritis: a new model for EHR-based research.

Cole TS, Frankovich J, Iyer S, Lependu P, Bauer-Mehren A, Shah NH.

Pediatr Rheumatol Online J. 2013 Dec 3;11(1):45. doi: 10.1186/1546-0096-11-45.


Mining clinical text for signals of adverse drug-drug interactions.

Iyer SV, Harpaz R, LePendu P, Bauer-Mehren A, Shah NH.

J Am Med Inform Assoc. 2014 Mar-Apr;21(2):353-62. doi: 10.1136/amiajnl-2013-001612. Epub 2013 Oct 24.


Drug-induced acute myocardial infarction: identifying 'prime suspects' from electronic healthcare records-based surveillance system.

Coloma PM, Schuemie MJ, Trifirò G, Furlong L, van Mulligen E, Bauer-Mehren A, Avillach P, Kors J, Sanz F, Mestres J, Oliveira JL, Boyer S, Helgee EA, Molokhia M, Matthews J, Prieto-Merino D, Gini R, Herings R, Mazzaglia G, Picelli G, Scotti L, Pedersen L, van der Lei J, Sturkenboom M; EU-ADR consortium.

PLoS One. 2013 Aug 28;8(8):e72148. doi: 10.1371/journal.pone.0072148. eCollection 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/8824e161-bf8f-4f78-81e0-a62a1540276d.


Response to "Logistic regression in signal detection: another piece added to the puzzle".

Harpaz R, DuMouchel W, LePendu P, Bauer-Mehren A, Ryan P, Shah NH.

Clin Pharmacol Ther. 2013 Sep;94(3):313. doi: 10.1038/clpt.2013.125. Epub 2013 Jun 12. No abstract available.


Practice-based evidence: profiling the safety of cilostazol by text-mining of clinical notes.

Leeper NJ, Bauer-Mehren A, Iyer SV, Lependu P, Olson C, Shah NH.

PLoS One. 2013 May 23;8(5):e63499. doi: 10.1371/journal.pone.0063499. Print 2013.


Integration of genomic information with biological networks using Cytoscape.

Bauer-Mehren A.

Methods Mol Biol. 2013;1021:37-61. doi: 10.1007/978-1-62703-450-0_3.


Pharmacovigilance using clinical notes.

LePendu P, Iyer SV, Bauer-Mehren A, Harpaz R, Mortensen JM, Podchiyska T, Ferris TA, Shah NH.

Clin Pharmacol Ther. 2013 Jun;93(6):547-55. doi: 10.1038/clpt.2013.47. Epub 2013 Mar 4.


Performance of pharmacovigilance signal-detection algorithms for the FDA adverse event reporting system.

Harpaz R, DuMouchel W, LePendu P, Bauer-Mehren A, Ryan P, Shah NH.

Clin Pharmacol Ther. 2013 Jun;93(6):539-46. doi: 10.1038/clpt.2013.24. Epub 2013 Feb 11.


The EU-ADR Web Platform: delivering advanced pharmacovigilance tools.

Oliveira JL, Lopes P, Nunes T, Campos D, Boyer S, Ahlberg E, van Mulligen EM, Kors JA, Singh B, Furlong LI, Sanz F, Bauer-Mehren A, Carrascosa MC, Mestres J, Avillach P, Diallo G, Díaz Acedo C, van der Lei J.

Pharmacoepidemiol Drug Saf. 2013 May;22(5):459-67. doi: 10.1002/pds.3375. Epub 2012 Dec 4.


Automatic filtering and substantiation of drug safety signals.

Bauer-Mehren A, van Mullingen EM, Avillach P, Carrascosa Mdel C, Garcia-Serna R, Piñero J, Singh B, Lopes P, Oliveira JL, Diallo G, Ahlberg Helgee E, Boyer S, Mestres J, Sanz F, Kors JA, Furlong LI.

PLoS Comput Biol. 2012;8(4):e1002457. doi: 10.1371/journal.pcbi.1002457. Epub 2012 Apr 5. Erratum in: PLoS Comput Biol. 2012 May;8(5): doi/10.1371/annotation/695450aa-95a0-491d-804d-470cbfa861e8.


Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseases.

Bauer-Mehren A, Bundschus M, Rautschka M, Mayer MA, Sanz F, Furlong LI.

PLoS One. 2011;6(6):e20284. doi: 10.1371/journal.pone.0020284. Epub 2011 Jun 14.


DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks.

Bauer-Mehren A, Rautschka M, Sanz F, Furlong LI.

Bioinformatics. 2010 Nov 15;26(22):2924-6. doi: 10.1093/bioinformatics/btq538. Epub 2010 Sep 21.


Prediction of 60 day case-fatality after aneurysmal subarachnoid haemorrhage: results from the International Subarachnoid Aneurysm Trial (ISAT).

Risselada R, Lingsma HF, Bauer-Mehren A, Friedrich CM, Molyneux AJ, Kerr RS, Yarnold J, Sneade M, Steyerberg EW, Sturkenboom MC.

Eur J Epidemiol. 2010 Apr;25(4):261-6. doi: 10.1007/s10654-010-9432-x. Epub 2010 Feb 14.


A novel multilevel statistical method for the study of the relationships between multireceptorial binding affinity profiles and in vivo endpoints.

Selent J, Bauer-Mehren A, López L, Loza MI, Sanz F, Pastor M.

Mol Pharmacol. 2010 Feb;77(2):149-58. doi: 10.1124/mol.109.060103. Epub 2009 Nov 10.


From SNPs to pathways: integration of functional effect of sequence variations on models of cell signalling pathways.

Bauer-Mehren A, Furlong LI, Rautschka M, Sanz F.

BMC Bioinformatics. 2009 Aug 27;10 Suppl 8:S6. doi: 10.1186/1471-2105-10-S8-S6.


Pathway databases and tools for their exploitation: benefits, current limitations and challenges.

Bauer-Mehren A, Furlong LI, Sanz F.

Mol Syst Biol. 2009;5:290. doi: 10.1038/msb.2009.47. Epub 2009 Jul 28.

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