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Brain Penetration of Lorlatinib: Cumulative Incidences of CNS and Non-CNS Progression with Lorlatinib in Patients with Previously Treated ALK-Positive Non-Small-Cell Lung Cancer.

Bauer TM, Shaw AT, Johnson ML, Navarro A, Gainor JF, Thurm H, Pithavala YK, Abbattista A, Peltz G, Felip E.

Target Oncol. 2020 Feb 14. doi: 10.1007/s11523-020-00702-4. [Epub ahead of print]


Digital Whole Slide Imaging Compared With Light Microscopy for Primary Diagnosis in Surgical Pathology: A Multicenter, Double-Blinded, Randomized Study of 2045 Cases.

Borowsky AD, Glassy EF, Wallace WD, Kallichanda NS, Behling CA, Miller DV, Oswal HN, Feddersen RM, Bakhtar OR, Mendoza AE, Molden DP, Saffer HL, Wixom CR, Albro JE, Cessna MH, Hall BJ, Lloyd IE, Bishop JW, Darrow MA, Gui D, Jen KY, Walby JAS, Bauer SM, Cortez DA, Gandhi P, Rodgers MM, Rodriguez RA, Martin DR, McConnell TG, Reynolds SJ, Spigel JH, Stepenaskie SA, Viktorova E, Magari R, Wharton KA Jr, Qiu J, Bauer TW.

Arch Pathol Lab Med. 2020 Feb 14. doi: 10.5858/arpa.2019-0569-OA. [Epub ahead of print]


Electrophysiology-based stratification of pancreatic tumorigenicity by label-free single-cell impedance cytometry.

McGrath JS, Honrado C, Moore JH, Adair SJ, Varhue WB, Salahi A, Farmehini V, Goudreau BJ, Nagdas S, Blais EM, Bauer TW, Swami NS.

Anal Chim Acta. 2020 Mar 8;1101:90-98. doi: 10.1016/j.aca.2019.12.033. Epub 2019 Dec 19.


The toxic effect of CuO of different dispersion degrees on the structure and ultrastructure of spring barley cells (Hordeum sativum distichum).

Fedorenko AG, Minkina TM, Chernikova NP, Fedorenko GM, Mandzhieva SS, Rajput VD, Burachevskaya MV, Chaplygin VA, Bauer TV, Sushkova SN, Soldatov AV.

Environ Geochem Health. 2020 Feb 5. doi: 10.1007/s10653-020-00530-5. [Epub ahead of print]


Global knockout of ROMK potassium channel worsens cardiac ischemia-reperfusion injury but cardiomyocyte-specific knockout does not: Implications for the identity of mitoKATP.

Papanicolaou KN, Ashok D, Liu T, Bauer TM, Sun J, Li Z, da Costa E, D'Orleans CC, Nathan S, Lefer DJ, Murphy E, Paolocci N, Foster DB, O'Rourke B.

J Mol Cell Cardiol. 2020 Jan 28. pii: S0022-2828(20)30022-5. doi: 10.1016/j.yjmcc.2020.01.010. [Epub ahead of print]


Transcatheter aortic valve implantation in nonagenarians: insights from the German Aortic Valve Registry (GARY).

Blumenstein J, Möllmann H, Bleiziffer S, Bauer T, Ensminger S, Bekeredjian R, Walther T, Frerker C, Beyersdorf F, Hamm C, Beckmann A.

Clin Res Cardiol. 2020 Jan 28. doi: 10.1007/s00392-020-01601-4. [Epub ahead of print]


Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4.

Antwi EB, Olins A, Teif VB, Bieg M, Bauer T, Gu Z, Brors B, Eils R, Olins D, Ishaque N.

Biol Open. 2020 Jan 27. pii: bio.044222. doi: 10.1242/bio.044222. [Epub ahead of print]


Risk factors for passive anterior tibial subluxation on MRI in complete ACL tear.

Sigonney G, Klouche S, Chevance V, Bauer T, Rousselin B, Judet O, Hardy P.

Orthop Traumatol Surg Res. 2020 Jan 23. pii: S1877-0568(19)30412-8. doi: 10.1016/j.otsr.2019.10.025. [Epub ahead of print]


The impact of cirrhosis and MELD score on postoperative morbidity and mortality among patients selected for liver resection.

Zaydfudim VM, Turrentine FE, Smolkin ME, Bauer TB, Adams RB, McMurry TL.

Am J Surg. 2020 Jan 20. pii: S0002-9610(20)30023-4. doi: 10.1016/j.amjsurg.2020.01.022. [Epub ahead of print]


Long-Distance Distribution of Atom-Photon Entanglement at Telecom Wavelength.

van Leent T, Bock M, Garthoff R, Redeker K, Zhang W, Bauer T, Rosenfeld W, Becher C, Weinfurter H.

Phys Rev Lett. 2020 Jan 10;124(1):010510. doi: 10.1103/PhysRevLett.124.010510.


Reply to Comment on 'Volatile biomarker in breath predicts lung cancer and pulmonary nodules'.

Phillips M, Bauer TL, Pass HI.

J Breath Res. 2020 Jan 24;14(2):028002. doi: 10.1088/1752-7163/ab6417. No abstract available.


Number and Station of Lymph Node Metastasis After Curative-intent Resection of Intrahepatic Cholangiocarcinoma Impact Prognosis.

Zhang XF, Xue F, Dong DH, Weiss M, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM.

Ann Surg. 2020 Jan 14. doi: 10.1097/SLA.0000000000003788. [Epub ahead of print]


Differential upregulation of host cell protein kinases by the replication of α-, β- and γ-herpesviruses provides a signature of virus-specific signalling.

Marschall M, Strojan H, Kiener R, Wangen C, Sonntag E, Müller R, Zeitträger I, Wagner S, Stamminger T, Milbradt J, Behrends U, Körber N, Bauer T, Schrödel S, Thirion C, Wagner R, Hutterer C.

J Gen Virol. 2020 Jan 20. doi: 10.1099/jgv.0.001370. [Epub ahead of print]


Adenosine signalling is prognostic for cancer outcome and has predictive utility for immunotherapeutic response.

Sidders B, Zhang P, Goodwin K, O'Connor G, Russell DL, Borodovsky A, Armenia J, McEwen R, Linghu B, Bendell JC, Bauer TM, Patel MR, Falchook GS, Merchant M, Pouliot G, Barrett JC, Dry JR, Woessner R, Sachsenmeier K.

Clin Cancer Res. 2020 Jan 17. pii: clincanres.2183.2019. doi: 10.1158/1078-0432.CCR-19-2183. [Epub ahead of print]


Role of Mitochondrial Calcium and the Permeability Transition Pore in Regulating Cell Death.

Bauer TM, Murphy E.

Circ Res. 2020 Jan 17;126(2):280-293. doi: 10.1161/CIRCRESAHA.119.316306. Epub 2020 Jan 16.


Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle-Cell Interactions.

Dal NK, Kocere A, Wohlmann J, Van Herck S, Bauer TA, Resseguier J, Bagherifam S, Hyldmo H, Barz M, De Geest BG, Fenaroli F.

Small. 2020 Feb;16(5):e1906719. doi: 10.1002/smll.201906719. Epub 2020 Jan 15.


JBJS Endorses Concerns Regarding Speculative Commercial Cell-Banking Services.

Bauer TW, Swiontkowski M.

J Bone Joint Surg Am. 2020 Jan 2;102(1):1. doi: 10.2106/JBJS.19.01268. No abstract available.


Using Patient Portals to Improve Patient Outcomes: Systematic Review.

Han HR, Gleason KT, Sun CA, Miller HN, Kang SJ, Chow S, Anderson R, Nagy P, Bauer T.

JMIR Hum Factors. 2019 Dec 19;6(4):e15038. doi: 10.2196/15038. Review.


Hair eruption initiates and commensal skin microbiota aggravate adverse events of anti-EGFR therapy.

Klufa J, Bauer T, Hanson B, Herbold C, Starkl P, Lichtenberger B, Srutkova D, Schulz D, Vujic I, Mohr T, Rappersberger K, Bodenmiller B, Kozakova H, Knapp S, Loy A, Sibilia M.

Sci Transl Med. 2019 Dec 11;11(522). pii: eaax2693. doi: 10.1126/scitranslmed.aax2693.


Redefining Conditional Overall and Disease-Free Survival After Curative Resection for Intrahepatic Cholangiocarcinoma: a Multi-institutional, International Study of 1221 patients.

Hu LS, Zhang XF, Weiss M, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM.

J Gastrointest Surg. 2019 Dec 10. doi: 10.1007/s11605-019-04472-x. [Epub ahead of print]


Better functional outcomes for ORIF in tibial eminence fracture treatment: a national comparative multicentric study of ORIF vs ARIF.

Pailhé R, Bauer T, Flecher X, Bonnevialle N, Roussignol X, Saragaglia D, Ehlinger M; SOFCOT.

Knee Surg Sports Traumatol Arthrosc. 2020 Feb;28(2):653-657. doi: 10.1007/s00167-019-05785-9. Epub 2019 Dec 3.


Plasma protein patterns as comprehensive indicators of health.

Williams SA, Kivimaki M, Langenberg C, Hingorani AD, Casas JP, Bouchard C, Jonasson C, Sarzynski MA, Shipley MJ, Alexander L, Ash J, Bauer T, Chadwick J, Datta G, DeLisle RK, Hagar Y, Hinterberg M, Ostroff R, Weiss S, Ganz P, Wareham NJ.

Nat Med. 2019 Dec;25(12):1851-1857. doi: 10.1038/s41591-019-0665-2. Epub 2019 Dec 2.


Circular Dichroism Measurement of Single Metal Nanoparticles Using Photothermal Imaging.

Spaeth P, Adhikari S, Le L, Jollans T, Pud S, Albrecht W, Bauer T, Caldarola M, Kuipers L, Orrit M.

Nano Lett. 2019 Dec 11;19(12):8934-8940. doi: 10.1021/acs.nanolett.9b03853. Epub 2019 Dec 2.


Phase 1 study of capmatinib in MET-positive solid tumor patients: Dose escalation and expansion of selected cohorts.

Bang YJ, Su WC, Schuler M, Nam DH, Lim WT, Bauer TM, Azaro A, Poon RTP, Hong D, Lin CC, Akimov M, Ghebremariam S, Zhao S, Giovannini M, Ma B.

Cancer Sci. 2020 Feb;111(2):536-547. doi: 10.1111/cas.14254. Epub 2019 Dec 30.


A novel class of cardioprotective small-molecule PTP inhibitors.

Antonucci S, Di Sante M, Sileikyte J, Deveraux J, Bauer T, Bround MJ, Menabò R, Paillard M, Alanova P, Carraro M, Ovize M, Molkentin JD, Cohen M, Forte MA, Bernardi P, Di Lisa F, Murphy E.

Pharmacol Res. 2020 Jan;151:104548. doi: 10.1016/j.phrs.2019.104548. Epub 2019 Nov 20.


Valve-in-Valve Implantation Using the ACURATE Neo in Degenerated Aortic Bioprostheses: An International Multicenter Analysis.

Holzamer A, Kim WK, Rück A, Sathananthan J, Keller L, Cosma J, Bauer T, Nef H, Amat-Santos IJ, Brinkert M, Husser O, Pellegrini C, Schofer J, Nerla R, Montorfano M, Giannini F, Stella P, Kuwata S, Hilker M, Castriota F, Ussia GP, Webb JG, Nietlispach F, Toggweiler S.

JACC Cardiovasc Interv. 2019 Nov 25;12(22):2309-2316. doi: 10.1016/j.jcin.2019.07.042.


Efficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study.

Piha-Paul SA, Taylor MH, Spitz D, Schwartzberg L, Beck JT, Bauer TM, Meric-Bernstam F, Purkayastha D, Karpiak L, Szpakowski S, Braiteh F.

Oncotarget. 2019 Nov 5;10(60):6526-6535. doi: 10.18632/oncotarget.27251. eCollection 2019 Nov 5.


Short-Term Microgravity Influences Cell Adhesion in Human Breast Cancer Cells.

Nassef MZ, Kopp S, Melnik D, Corydon TJ, Sahana J, Krüger M, Wehland M, Bauer TJ, Liemersdorf C, Hemmersbach R, Infanger M, Grimm D.

Int J Mol Sci. 2019 Nov 15;20(22). pii: E5730. doi: 10.3390/ijms20225730.


A Machine-Based Approach to Preoperatively Identify Patients with the Most and Least Benefit Associated with Resection for Intrahepatic Cholangiocarcinoma: An International Multi-institutional Analysis of 1146 Patients.

Tsilimigras DI, Mehta R, Moris D, Sahara K, Bagante F, Paredes AZ, Moro A, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Soubrane O, Koerkamp BG, Endo I, Pawlik TM.

Ann Surg Oncol. 2019 Nov 14. doi: 10.1245/s10434-019-08067-3. [Epub ahead of print]


Multiplex Antibody Measurement for Post-treatment Follow-up of Staphylococcal Prosthetic Joint Infection: A Diagnostic Pilot Study.

Bauer T, Marmor S, Ghout I, Salomon E, Sayed FE, Heym B, Rottman M, Gaillard JL, Roux AL.

J Bone Jt Infect. 2019 Sep 26;4(5):227-233. doi: 10.7150/jbji.36015. eCollection 2019.


JBJS Will Require Adherence to ARRIVE Guidelines for Animal Research to Reduce Bias and Improve Quality of Reporting.

Bauer TW, Bechtold JE, Swiontkowski MF.

J Bone Joint Surg Am. 2019 Nov 6;101(21):1891-1893. doi: 10.2106/JBJS.19.01001. No abstract available.


Population pharmacokinetics of vactosertib, a new TGF-β receptor type Ι inhibitor, in patients with advanced solid tumors.

Jung SY, Yug JS, Clarke JM, Bauer TM, Keedy VL, Hwang S, Kim SJ, Chung EK, Lee JI.

Cancer Chemother Pharmacol. 2020 Jan;85(1):173-183. doi: 10.1007/s00280-019-03979-z. Epub 2019 Oct 30.


Augmenting cancer cell proteomics with cellular images - A semantic approach to understand focal adhesion.

Bauer TJ, Gombocz E, Krüger M, Sahana J, Corydon TJ, Bauer J, Infanger M, Grimm D.

J Biomed Inform. 2019 Dec;100:103320. doi: 10.1016/j.jbi.2019.103320. Epub 2019 Oct 24.


Lorlatinib in advanced ROS1-positive non-small-cell lung cancer: a multicentre, open-label, single-arm, phase 1-2 trial.

Shaw AT, Solomon BJ, Chiari R, Riely GJ, Besse B, Soo RA, Kao S, Lin CC, Bauer TM, Clancy JS, Thurm H, Martini JF, Peltz G, Abbattista A, Li S, Ou SI.

Lancet Oncol. 2019 Dec;20(12):1691-1701. doi: 10.1016/S1470-2045(19)30655-2. Epub 2019 Oct 25.


Six months follow-up of protected high-risk percutaneous coronary intervention with the microaxial Impella pump: results from the German Impella registry.

Baumann S, Werner N, Al-Rashid F, Schäfer A, Bauer T, Sotoudeh R, Bojara W, Shamekhi J, Sinning JM, Becher T, Eder F, Akin I.

Coron Artery Dis. 2019 Oct 23. doi: 10.1097/MCA.0000000000000824. [Epub ahead of print]


Efficacy of cotrimoxazole (Sulfamethoxazole-Trimethoprim) as a salvage therapy for the treatment of bone and joint infections (BJIs).

Deconinck L, Dinh A, Nich C, Tritz T, Matt M, Senard O, Bessis S, Bauer T, Rottman M, Salomon J, Bouchand F, Davido B.

PLoS One. 2019 Oct 17;14(10):e0224106. doi: 10.1371/journal.pone.0224106. eCollection 2019.


Comparison of different semi-automated cfDNA extraction methods in combination with UMI-based targeted sequencing.

Streubel A, Stenzinger A, Stephan-Falkenau S, Kollmeier J, Misch D, Blum TG, Bauer T, Landt O, Am Ende A, Schirmacher P, Mairinger T, Endris V.

Oncotarget. 2019 Oct 1;10(55):5690-5702. doi: 10.18632/oncotarget.27183. eCollection 2019 Oct 1.


Genomic profiling of cell-free circulating tumor DNA in patients with colorectal cancer and its fidelity to the genomics of the tumor biopsy.

Li G, Pavlick D, Chung JH, Bauer T, Tan BA, Peguero J, Ward P, Kallab A, Bufill J, Hoffman A, Sadiq A, Edenfield J, He J, Cooke M, Hughes J, Forcier B, Nahas M, Stephens P, Ali SM, Schrock AB, Ross JS, Miller VA, Gregg JP.

J Gastrointest Oncol. 2019 Oct;10(5):831-840. doi: 10.21037/jgo.2019.05.05.


Pegilodecakin combined with pembrolizumab or nivolumab for patients with advanced solid tumours (IVY): a multicentre, multicohort, open-label, phase 1b trial.

Naing A, Wong DJ, Infante JR, Korn WM, Aljumaily R, Papadopoulos KP, Autio KA, Pant S, Bauer TM, Drakaki A, Daver NG, Hung A, Ratti N, McCauley S, Van Vlasselaer P, Verma R, Ferry D, Oft M, Diab A, Garon EB, Tannir NM.

Lancet Oncol. 2019 Nov;20(11):1544-1555. doi: 10.1016/S1470-2045(19)30514-5. Epub 2019 Sep 25. Erratum in: Lancet Oncol. 2019 Dec;20(12):e663.


Prognostic significance of the pattern of pathological N1 lymph node metastases for non-small cell lung cancer.

Griff S, Taber S, Bauer TT, Pfannschmidt J.

J Thorac Dis. 2019 Aug;11(8):3449-3458. doi: 10.21037/jtd.2019.07.73.


The modular structure of α/β-hydrolases.

Bauer TL, Buchholz PCF, Pleiss J.

FEBS J. 2019 Sep 23. doi: 10.1111/febs.15071. [Epub ahead of print]


Perfused murine heart optical transmission spectroscopy using optical catheter and integrating sphere: Effects of ischemia/reperfusion.

Bauer TM, Giles AV, Sun J, Femnou A, Covian R, Murphy E, Balaban RS.

Anal Biochem. 2019 Dec 1;586:113443. doi: 10.1016/j.ab.2019.113443. Epub 2019 Sep 17.


Correction to: Neuroendocrine Liver Metastasis: Prognostic Implications of Primary Tumor Site on Patients Undergoing Curative Intent Liver Surgery.

Spolverato G, Bagante F, Aldrighetti L, Poultsides G, Bauer TW, Fields RC, Marques HP, Weiss M, Maithel SK, Pawlik TM.

J Gastrointest Surg. 2020 Jan;24(1):231. doi: 10.1007/s11605-019-04371-1.


Contribution of arthroscopy to the management of intra-articular distal radius fractures: Knowledge update based on a systematic 10-year literature review.

Saab M, Guerre E, Chantelot C, Clavert P, Ehlinger M, Bauer T; SoFCOT.

Orthop Traumatol Surg Res. 2019 Dec;105(8):1617-1625. doi: 10.1016/j.otsr.2019.06.016. Epub 2019 Sep 13. Review.


Fractional flow reserve and frequency of PCI in patients with coronary artery disease.

Dörr O, Liebetrau C, Weferling M, Hoffmann F, Forderer N, Keller T, Boeder N, Blachutzik F, Keranov S, Bauer P, Bauer T, Hamm CW, Nef H.

Herz. 2019 Sep 4. doi: 10.1007/s00059-019-04848-4. [Epub ahead of print]


Dynamics of bacterial communities in alfalfa and mung bean sprouts during refrigerated conditions.

Keshri J, Krouptiski Y, Abu-Fani L, Achmon Y, Bauer TS, Zarka O, Maler I, Pinto R, Sela Saldinger S.

Food Microbiol. 2019 Dec;84:103261. doi: 10.1016/ Epub 2019 Jul 6.


Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth.

Nagdas S, Kashatus JA, Nascimento A, Hussain SS, Trainor RE, Pollock SR, Adair SJ, Michaels AD, Sesaki H, Stelow EB, Bauer TW, Kashatus DF.

Cell Rep. 2019 Aug 13;28(7):1845-1859.e5. doi: 10.1016/j.celrep.2019.07.031.


Impact of Vascular Function on Maximum Power Output in Elite Handball Athletes.

Bauer P, Kraushaar L, Most A, Hölscher S, Tajmiri-Gondai S, Dörr O, Troidl C, Bauer T, Nef H, Hamm CW, Keller T.

Res Q Exerc Sport. 2019 Dec;90(4):600-608. doi: 10.1080/02701367.2019.1639602. Epub 2019 Aug 9.


Random peptide mixtures entrapped within a copper-cuprite matrix: new antimicrobial agent against methicillin-resistant Staphylococcus aureus.

Bauer TS, Menagen B, Avnir D, Hayouka Z.

Sci Rep. 2019 Aug 2;9(1):11215. doi: 10.1038/s41598-019-47315-0.


A phase Ib, open-label, dose-escalation study of the safety and pharmacology of taselisib (GDC-0032) in combination with either docetaxel or paclitaxel in patients with HER2-negative, locally advanced, or metastatic breast cancer.

Abramson VG, Oliveira M, Cervantes A, Wildiers H, Patel MR, Bauer TM, Bedard PL, Becerra C, Richey S, Wei MC, Reyner E, Bond J, Cui N, Wilson TR, Moore HM, Saura C, Krop IE.

Breast Cancer Res Treat. 2019 Nov;178(1):121-133. doi: 10.1007/s10549-019-05360-3. Epub 2019 Jul 31.


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