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Items: 25

1.

Photoreversible interconversion of a phytochrome photosensory module in the crystalline state.

Burgie ES, Clinger JA, Miller MD, Brewster AS, Aller P, Butryn A, Fuller FD, Gul S, Young ID, Pham CC, Kim IS, Bhowmick A, O'Riordan LJ, Sutherlin KD, Heinemann JV, Batyuk A, Alonso-Mori R, Hunter MS, Koglin JE, Yano J, Yachandra VK, Sauter NK, Cohen AE, Kern J, Orville AM, Phillips GN Jr, Vierstra RD.

Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):300-307. doi: 10.1073/pnas.1912041116. Epub 2019 Dec 18.

2.

Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis.

Dasgupta M, Budday D, de Oliveira SHP, Madzelan P, Marchany-Rivera D, Seravalli J, Hayes B, Sierra RG, Boutet S, Hunter MS, Alonso-Mori R, Batyuk A, Wierman J, Lyubimov A, Brewster AS, Sauter NK, Applegate GA, Tiwari VK, Berkowitz DB, Thompson MC, Cohen AE, Fraser JS, Wall ME, van den Bedem H, Wilson MA.

Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25634-25640. doi: 10.1073/pnas.1901864116. Epub 2019 Dec 4.

PMID:
31801874
3.

Toward G protein-coupled receptor structure-based drug design using X-ray lasers.

Ishchenko A, Stauch B, Han GW, Batyuk A, Shiriaeva A, Li C, Zatsepin N, Weierstall U, Liu W, Nango E, Nakane T, Tanaka R, Tono K, Joti Y, Iwata S, Moraes I, Gati C, Cherezov V.

IUCrJ. 2019 Oct 24;6(Pt 6):1106-1119. doi: 10.1107/S2052252519013137. eCollection 2019 Nov 1.

4.

3D printed droplet generation devices for serial femtosecond crystallography enabled by surface coating.

Echelmeier A, Kim D, Cruz Villarreal J, Coe J, Quintana S, Brehm G, Egatz-Gomez A, Nazari R, Sierra RG, Koglin JE, Batyuk A, Hunter MS, Boutet S, Zatsepin N, Kirian RA, Grant TD, Fromme P, Ros A.

J Appl Crystallogr. 2019 Aug 29;52(Pt 5):997-1008. doi: 10.1107/S1600576719010343. eCollection 2019 Oct 1.

PMID:
31636518
5.

Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.

Luginina A, Gusach A, Marin E, Mishin A, Brouillette R, Popov P, Shiriaeva A, Besserer-Offroy É, Longpré JM, Lyapina E, Ishchenko A, Patel N, Polovinkin V, Safronova N, Bogorodskiy A, Edelweiss E, Hu H, Weierstall U, Liu W, Batyuk A, Gordeliy V, Han GW, Sarret P, Katritch V, Borshchevskiy V, Cherezov V.

Sci Adv. 2019 Oct 9;5(10):eaax2518. doi: 10.1126/sciadv.aax2518. eCollection 2019 Oct.

6.

Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin.

Nass Kovacs G, Colletier JP, Grünbein ML, Yang Y, Stensitzki T, Batyuk A, Carbajo S, Doak RB, Ehrenberg D, Foucar L, Gasper R, Gorel A, Hilpert M, Kloos M, Koglin JE, Reinstein J, Roome CM, Schlesinger R, Seaberg M, Shoeman RL, Stricker M, Boutet S, Haacke S, Heberle J, Heyne K, Domratcheva T, Barends TRM, Schlichting I.

Nat Commun. 2019 Jul 18;10(1):3177. doi: 10.1038/s41467-019-10758-0.

7.

Publisher Correction: Structural basis of ligand recognition at the human MT1 melatonin receptor.

Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang XP, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, Grant TD, Grandner JM, Shiriaeva A, Olsen RHJ, Tribo AR, Yous S, Stevens RC, Weierstall U, Katritch V, Roth BL, Liu W, Cherezov V.

Nature. 2019 May;569(7756):E6. doi: 10.1038/s41586-019-1209-0.

PMID:
31048811
8.

Structural basis of ligand recognition at the human MT1 melatonin receptor.

Stauch B, Johansson LC, McCorvy JD, Patel N, Han GW, Huang XP, Gati C, Batyuk A, Slocum ST, Ishchenko A, Brehm W, White TA, Michaelian N, Madsen C, Zhu L, Grant TD, Grandner JM, Shiriaeva A, Olsen RHJ, Tribo AR, Yous S, Stevens RC, Weierstall U, Katritch V, Roth BL, Liu W, Cherezov V.

Nature. 2019 May;569(7755):284-288. doi: 10.1038/s41586-019-1141-3. Epub 2019 Apr 24. Erratum in: Nature. 2019 May 3;:.

9.

XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity.

Johansson LC, Stauch B, McCorvy JD, Han GW, Patel N, Huang XP, Batyuk A, Gati C, Slocum ST, Li C, Grandner JM, Hao S, Olsen RHJ, Tribo AR, Zaare S, Zhu L, Zatsepin NA, Weierstall U, Yous S, Stevens RC, Liu W, Roth BL, Katritch V, Cherezov V.

Nature. 2019 May;569(7755):289-292. doi: 10.1038/s41586-019-1144-0. Epub 2019 Apr 24.

10.

The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source.

Sierra RG, Batyuk A, Sun Z, Aquila A, Hunter MS, Lane TJ, Liang M, Yoon CH, Alonso-Mori R, Armenta R, Castagna JC, Hollenbeck M, Osier TO, Hayes M, Aldrich J, Curtis R, Koglin JE, Rendahl T, Rodriguez E, Carbajo S, Guillet S, Paul R, Hart P, Nakahara K, Carini G, DeMirci H, Dao EH, Hayes BM, Rao YP, Chollet M, Feng Y, Fuller FD, Kupitz C, Sato T, Seaberg MH, Song S, van Driel TB, Yavas H, Zhu D, Cohen AE, Wakatsuki S, Boutet S.

J Synchrotron Radiat. 2019 Mar 1;26(Pt 2):346-357. doi: 10.1107/S1600577519001577. Epub 2019 Feb 22.

11.

Snapshot of an oxygen intermediate in the catalytic reaction of cytochrome c oxidase.

Ishigami I, Lewis-Ballester A, Echelmeier A, Brehm G, Zatsepin NA, Grant TD, Coe JD, Lisova S, Nelson G, Zhang S, Dobson ZF, Boutet S, Sierra RG, Batyuk A, Fromme P, Fromme R, Spence JCH, Ros A, Yeh SR, Rousseau DL.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3572-3577. doi: 10.1073/pnas.1814526116. Epub 2019 Feb 11.

12.

Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor.

Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, Katritch V, Cherezov V, Hanson MA, Stevens RC.

Nat Chem Biol. 2019 Feb;15(2):206. doi: 10.1038/s41589-018-0214-1.

PMID:
30573766
13.

Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor.

Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, Katritch V, Cherezov V, Hanson MA, Stevens RC.

Nat Chem Biol. 2019 Jan;15(1):11-17. doi: 10.1038/s41589-018-0160-y. Epub 2018 Dec 3. Erratum in: Nat Chem Biol. 2019 Feb;15(2):206.

14.

Structures of the intermediates of Kok's photosynthetic water oxidation clock.

Kern J, Chatterjee R, Young ID, Fuller FD, Lassalle L, Ibrahim M, Gul S, Fransson T, Brewster AS, Alonso-Mori R, Hussein R, Zhang M, Douthit L, de Lichtenberg C, Cheah MH, Shevela D, Wersig J, Seuffert I, Sokaras D, Pastor E, Weninger C, Kroll T, Sierra RG, Aller P, Butryn A, Orville AM, Liang M, Batyuk A, Koglin JE, Carbajo S, Boutet S, Moriarty NW, Holton JM, Dobbek H, Adams PD, Bergmann U, Sauter NK, Zouni A, Messinger J, Yano J, Yachandra VK.

Nature. 2018 Nov;563(7731):421-425. doi: 10.1038/s41586-018-0681-2. Epub 2018 Nov 7.

15.

Design and applications of a clamp for Green Fluorescent Protein with picomolar affinity.

Hansen S, Stüber JC, Ernst P, Koch A, Bojar D, Batyuk A, Plückthun A.

Sci Rep. 2017 Nov 24;7(1):16292. doi: 10.1038/s41598-017-15711-z.

16.

Structural Basis for the Selective Inhibition of c-Jun N-Terminal Kinase 1 Determined by Rigid DARPin-DARPin Fusions.

Wu Y, Honegger A, Batyuk A, Mittl PRE, Plückthun A.

J Mol Biol. 2018 Jul 6;430(14):2128-2138. doi: 10.1016/j.jmb.2017.10.032. Epub 2017 Nov 8.

PMID:
29126898
17.

Rigidly connected multispecific artificial binders with adjustable geometries.

Wu Y, Batyuk A, Honegger A, Brandl F, Mittl PRE, Plückthun A.

Sci Rep. 2017 Sep 11;7(1):11217. doi: 10.1038/s41598-017-11472-x.

18.

Rigidity of the extracellular part of HER2: Evidence from engineering subdomain interfaces and shared-helix DARPin-DARPin fusions.

Jost C, Stüber JC, Honegger A, Wu Y, Batyuk A, Plückthun A.

Protein Sci. 2017 Sep;26(9):1796-1806. doi: 10.1002/pro.3216. Epub 2017 Jul 5.

19.

Se-SAD serial femtosecond crystallography datasets from selenobiotinyl-streptavidin.

Yoon CH, DeMirci H, Sierra RG, Dao EH, Ahmadi R, Aksit F, Aquila AL, Batyuk A, Ciftci H, Guillet S, Hayes MJ, Hayes B, Lane TJ, Liang M, Lundström U, Koglin JE, Mgbam P, Rao Y, Rendahl T, Rodriguez E, Zhang L, Wakatsuki S, Boutet S, Holton JM, Hunter MS.

Sci Data. 2017 Apr 25;4:170055. doi: 10.1038/sdata.2017.55.

20.

Structural basis for selectivity and diversity in angiotensin II receptors.

Zhang H, Han GW, Batyuk A, Ishchenko A, White KL, Patel N, Sadybekov A, Zamlynny B, Rudd MT, Hollenstein K, Tolstikova A, White TA, Hunter MS, Weierstall U, Liu W, Babaoglu K, Moore EL, Katz RD, Shipman JM, Garcia-Calvo M, Sharma S, Sheth P, Soisson SM, Stevens RC, Katritch V, Cherezov V.

Nature. 2017 Apr 20;544(7650):327-332. doi: 10.1038/nature22035. Epub 2017 Apr 5.

21.

Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.

Batyuk A, Galli L, Ishchenko A, Han GW, Gati C, Popov PA, Lee MY, Stauch B, White TA, Barty A, Aquila A, Hunter MS, Liang M, Boutet S, Pu M, Liu ZJ, Nelson G, James D, Li C, Zhao Y, Spence JC, Liu W, Fromme P, Katritch V, Weierstall U, Stevens RC, Cherezov V.

Sci Adv. 2016 Sep 23;2(9):e1600292. eCollection 2016 Sep.

22.

DARPin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography.

Batyuk A, Wu Y, Honegger A, Heberling MM, Plückthun A.

J Mol Biol. 2016 Apr 24;428(8):1574-88. doi: 10.1016/j.jmb.2016.03.002. Epub 2016 Mar 11.

PMID:
26975886
23.

Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools.

Schütz M, Batyuk A, Klenk C, Kummer L, de Picciotto S, Gülbakan B, Wu Y, Newby GA, Zosel F, Schöppe J, Sedlák E, Mittl PRE, Zenobi R, Wittrup KD, Plückthun A.

J Mol Biol. 2016 Mar 27;428(6):1272-1289. doi: 10.1016/j.jmb.2016.01.017. Epub 2016 Jan 23.

PMID:
26812208
24.

Phase behavior of a designed cyclopropyl analogue of monoolein: implications for low-temperature membrane protein crystallization.

Salvati Manni L, Zabara A, Osornio YM, Schöppe J, Batyuk A, Plückthun A, Siegel JS, Mezzenga R, Landau EM.

Angew Chem Int Ed Engl. 2015 Jan 12;54(3):1027-31. doi: 10.1002/anie.201409791. Epub 2014 Nov 21.

PMID:
25418121
25.

Structure of signaling-competent neurotensin receptor 1 obtained by directed evolution in Escherichia coli.

Egloff P, Hillenbrand M, Klenk C, Batyuk A, Heine P, Balada S, Schlinkmann KM, Scott DJ, Schütz M, Plückthun A.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):E655-62. doi: 10.1073/pnas.1317903111. Epub 2014 Jan 22.

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