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Items: 1 to 50 of 85

1.

Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling.

McGuire VA, Gray A, Monk CE, Santos SG, Lee K, Aubareda A, Crowe J, Ronkina N, Schwermann J, Batty IH, Leslie NR, Dean JL, O'Keefe SJ, Boothby M, Gaestel M, Arthur JS.

Mol Cell Biol. 2013 Nov;33(21):4152-65. doi: 10.1128/MCB.01691-12. Epub 2013 Aug 26.

2.

IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold.

Dixon MJ, Gray A, Schenning M, Agacan M, Tempel W, Tong Y, Nedyalkova L, Park HW, Leslie NR, van Aalten DM, Downes CP, Batty IH.

J Biol Chem. 2012 Jun 29;287(27):22483-96. doi: 10.1074/jbc.M112.352773. Epub 2012 Apr 5.

3.

Distinct inactivation of PI3K signalling by PTEN and 5-phosphatases.

Leslie NR, Dixon MJ, Schenning M, Gray A, Batty IH.

Adv Biol Regul. 2012 Jan;52(1):205-13. Review. No abstract available.

PMID:
21930147
4.

A screen for novel phosphoinositide 3-kinase effector proteins.

Dixon MJ, Gray A, Boisvert FM, Agacan M, Morrice NA, Gourlay R, Leslie NR, Downes CP, Batty IH.

Mol Cell Proteomics. 2011 Apr;10(4):M110.003178. doi: 10.1074/mcp.M110.003178. Epub 2011 Jan 24.

5.

Understanding PTEN regulation: PIP2, polarity and protein stability.

Leslie NR, Batty IH, Maccario H, Davidson L, Downes CP.

Oncogene. 2008 Sep 18;27(41):5464-76. doi: 10.1038/onc.2008.243. Review.

PMID:
18794881
6.

Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation.

Hale BG, Batty IH, Downes CP, Randall RE.

J Biol Chem. 2008 Jan 18;283(3):1372-80. Epub 2007 Nov 20.

7.
8.

Loss of PTEN selectively desensitizes upstream IGF1 and insulin signaling.

Lackey J, Barnett J, Davidson L, Batty IH, Leslie NR, Downes CP.

Oncogene. 2007 Nov 1;26(50):7132-42. Epub 2007 May 7.

9.

Metabolic switching of PI3K-dependent lipid signals.

Downes CP, Leslie NR, Batty IH, van der Kaay J.

Biochem Soc Trans. 2007 Apr;35(Pt 2):188-92.

PMID:
17371235
10.

The regulation of membrane to cytosol partitioning of signalling proteins by phosphoinositides and their soluble headgroups.

Downes CP, Gray A, Fairservice A, Safrany ST, Batty IH, Fleming I.

Biochem Soc Trans. 2005 Dec;33(Pt 6):1303-7.

PMID:
16246104
11.
12.

Acute regulation of the tumour suppressor phosphatase, PTEN, by anionic lipids and reactive oxygen species.

Downes CP, Walker S, McConnachie G, Lindsay Y, Batty IH, Leslie NR.

Biochem Soc Trans. 2004 Apr;32(Pt 2):338-42. Review.

PMID:
15046604
14.

The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif.

Walker SM, Leslie NR, Perera NM, Batty IH, Downes CP.

Biochem J. 2004 Apr 15;379(Pt 2):301-7.

15.
17.

Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.

Hajduch E, Balendran A, Batty IH, Litherland GJ, Blair AS, Downes CP, Hundal HS.

Diabetologia. 2001 Feb;44(2):173-83.

PMID:
11270673
18.
19.

Serotonin (5-Hydroxytryptamine), a novel regulator of glucose transport in rat skeletal muscle.

Hajduch E, Rencurel F, Balendran A, Batty IH, Downes CP, Hundal HS.

J Biol Chem. 1999 May 7;274(19):13563-8.

20.

The lipid phosphatase activity of PTEN is critical for its tumor supressor function.

Myers MP, Pass I, Batty IH, Van der Kaay J, Stolarov JP, Hemmings BA, Wigler MH, Downes CP, Tonks NK.

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13513-8.

22.
23.

Cross-talk between phospholipase C and phosphoinositide 3-kinase signalling pathways.

Batty IH, Hickinson DM, Downes CP.

Biochem Soc Trans. 1997 Nov;25(4):1132-7. Review.

PMID:
9449962
24.

Inositol phospholipid 3-kinase is activated by cellular stress but is not required for the stress-induced activation of glucose transport in L6 rat skeletal muscle cells.

McDowell HE, Walker T, Hajduch E, Christie G, Batty IH, Downes CP, Hundal HS.

Eur J Biochem. 1997 Jul 1;247(1):306-13.

29.

Inositol lipid signalling exacts a transfer fee.

Downes CP, Batty IH.

Curr Biol. 1993 Nov 1;3(11):794-6. No abstract available.

PMID:
15335851
30.

The characteristics, capacity and receptor regulation of inositol uptake in 1321N1 astrocytoma cells.

Batty IH, Michie A, Fennel M, Downes CP.

Biochem J. 1993 Aug 15;294 ( Pt 1):49-55.

31.

Lithium and myo-inositol homeostasis.

Gani D, Downes CP, Batty I, Bramham J.

Biochim Biophys Acta. 1993 Jun 30;1177(3):253-69. Review. No abstract available.

PMID:
8391849
32.

Localisation of agonist stimulated CMP-phosphatidate accumulation in single mammalian neurones.

Bevilacqua JA, Batty IH, Downes CP, Lowenstein PR.

Biochem Soc Trans. 1993 May;21(2):118S. No abstract available.

PMID:
8359374
35.

Formation of inositol polyphosphates in airway smooth muscle after muscarinic receptor stimulation.

Chilvers ER, Batty IH, Barnes PJ, Nahorski SR.

J Pharmacol Exp Ther. 1990 Feb;252(2):786-91.

PMID:
2313600
36.

A simple enzymic method to separate [3H]inositol 1,4,5- and 1,3,4-trisphosphate isomers in tissue extracts.

Kennedy ED, Batty IH, Chilvers ER, Nahorski SR.

Biochem J. 1989 May 15;260(1):283-6.

39.
40.

Dopamine receptor stimulation does not affect phosphoinositide hydrolysis in slices of rat striatum.

Kelly E, Batty I, Nahorski SR.

J Neurochem. 1988 Sep;51(3):918-24.

PMID:
2842457
42.

Receptors and phosphoinositide metabolism in the central nervous system.

Nahorski SR, Kendall DA, Batty I.

Biochem Pharmacol. 1986 Aug 1;35(15):2447-53. Review. No abstract available.

PMID:
2427081
43.

The use and standardization of multicomponent veterinary vaccines.

Walker PD, Batty I.

Dev Biol Stand. 1986;65:227-36. Review.

PMID:
3549398
45.
46.

Active and passive immunization to protect against antibiotic associated caecitis in hamsters.

Fernie DS, Thomson RO, Batty I, Walker PD.

Dev Biol Stand. 1983;53:325-32.

PMID:
6873474
47.

Quality control of fluorescein isothiocyanate-labeled reagents.

Chantler S, Batty I.

Ann N Y Acad Sci. 1983;420:68-73.

PMID:
6426363
48.

Observations on vaccine and post-infection immunity in contagious equine metritis.

Fernie DS, Batty I, Walker PD, Platt H, Mackintosh ME, Simpson DJ.

Res Vet Sci. 1980 May;28(3):362-7.

PMID:
7414090
49.

IUIS standardization.

Batty I.

J Immunol Methods. 1980;33(4):391-2. No abstract available.

PMID:
6989922
50.

The typing of Cl. perfringens and the veterinary background.

Walker PD, Batty I, Egerton JR.

P N G Med J. 1979 Mar;22(1):50-6. No abstract available.

PMID:
233176

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