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Physiologically Based Pharmacokinetic Modelling to Identify Pharmacokinetic Parameters Driving Drug Exposure Changes in the Elderly.

Stader F, Kinvig H, Penny MA, Battegay M, Siccardi M, Marzolini C.

Clin Pharmacokinet. 2019 Oct 4. doi: 10.1007/s40262-019-00822-9. [Epub ahead of print]


Screening HIV-positive men who have sex with men for hepatitis C re-infection risk: is a single question on condom-use enough? A sensitivity analysis.

Künzler-Heule P, Engberg S, Battegay M, Schmidt AJ, Fierz K, Nguyen H, Kocher A, Nöstlinger C, Hampel B, Stöckle M, Béguelin C, Delaloye J, Schmid P, Flepp M, Rougement M, Braun DL, Fehr J, Nicca D; Swiss HIV Cohort Study (SHCS).

BMC Infect Dis. 2019 Sep 18;19(1):821. doi: 10.1186/s12879-019-4456-7.


Prevalence and management of drug-drug interactions with antiretroviral treatment in 2069 people living with HIV in rural Tanzania: a prospective cohort study.

Schlaeppi C, Vanobberghen F, Sikalengo G, Glass TR, Ndege RC, Foe G, Kuemmerle A, Paris DH, Battegay M, Marzolini C, Weisser M; Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) study group.

HIV Med. 2019 Sep 18. doi: 10.1111/hiv.12801. [Epub ahead of print]


Safety and tolerance of lymph node biopsies from chronic HIV-1 volunteers in rural Tanzania.

Mkindi CG, Marandu EA, Masawa N, Bani F, Nyuri A, Byakuzana T, Klimkait T, Ding S, Pantaleo G, Battegay M, Orlova-Fink N, Weisser-Rohacek M, Daubenberger C.

BMC Res Notes. 2019 Sep 6;12(1):561. doi: 10.1186/s13104-019-4600-x.


Pharmacokinetic profiles of boosted darunavir, dolutegravir and lamivudine in aging patients enrolled in the Swiss HIV Cohort Study.

Courlet P, Stader F, Guidi M, Saldanha SA, Stoeckle M, Cavassini M, Battegay M, Buclin T, Decosterd LA, Marzolini C; Swiss HIV Cohort Study.

AIDS. 2019 Sep 3. doi: 10.1097/QAD.0000000000002372. [Epub ahead of print]


VIBRA trial - Effect of village-based refill of ART following home-based same-day ART initiation vs clinic-based ART refill on viral suppression among individuals living with HIV: protocol of a cluster-randomized clinical trial in rural Lesotho.

Amstutz A, Lejone TI, Khesa L, Muhairwe J, Nsakala BL, Tlali K, Bresser M, Tediosi F, Kopo M, Kao M, Klimkait T, Battegay M, Glass TR, Labhardt ND.

Trials. 2019 Aug 22;20(1):522. doi: 10.1186/s13063-019-3510-5.


Identification of influenza urban transmission patterns by geographical, epidemiological and whole genome sequencing data: protocol for an observational study.

Egli A, Saalfrank C, Goldman N, Brunner M, Hollenstein Y, Vogel T, Augustin N, Wüthrich D, Seth-Smith HMB, Roth E, Syedbasha M, Mueller NF, Vogt D, Bauer J, Amar-Sliwa N, Meinel DM, Dubuis O, Naegele M, Tschudin-Sutter S, Buser A, Nickel CH, Zeller A, Ritz N, Battegay M, Stadler T, Schneider-Sliwa R.

BMJ Open. 2019 Aug 20;9(8):e030913. doi: 10.1136/bmjopen-2019-030913.


The HOSENG trial - Effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage: protocol of a cluster-randomized clinical trial in rural Lesotho.

Amstutz A, Lejone TI, Khesa L, Muhairwe J, Nsakala BL, Tlali K, Bresser M, Vanobberghen F, Kopo M, Kao M, Klimkait T, Battegay M, Labhardt ND, Glass TR.

Trials. 2019 Aug 13;20(1):496. doi: 10.1186/s13063-019-3469-2.


Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART.

Bachmann N, von Siebenthal C, Vongrad V, Turk T, Neumann K, Beerenwinkel N, Bogojeska J, Fellay J, Roth V, Kok YL, Thorball CW, Borghesi A, Parbhoo S, Wieser M, Böni J, Perreau M, Klimkait T, Yerly S, Battegay M, Rauch A, Hoffmann M, Bernasconi E, Cavassini M, Kouyos RD, Günthard HF, Metzner KJ; Swiss HIV Cohort Study.

Nat Commun. 2019 Jul 19;10(1):3193. doi: 10.1038/s41467-019-10884-9.


Impact of health insurance status on surgical site infection incidence: A prospective cohort study.

Duggan BT, Roth JA, Dangel M, Battegay M, Widmer AF.

Infect Control Hosp Epidemiol. 2019 Sep;40(9):1063-1065. doi: 10.1017/ice.2019.195. Epub 2019 Jul 16.


HIV Transmission Chains Exhibit Greater HLA-B Homogeneity Than Randomly Expected.

Nguyen H, Thorball CW, Fellay J, Böni J, Yerly S, Perreau M, Klimkait T, Kusejko K, Bachmann N, Chaudron SE, Paioni P, Thurnheer MC, Battegay M, Cavassini M, Vernazza P, Bernasconi E, Günthard HF, Kouyos R; Swiss HIV Cohort Study.

J Acquir Immune Defic Syndr. 2019 Aug 15;81(5):508-515. doi: 10.1097/QAI.0000000000002077.


Why do sub-Saharan Africans present late for HIV care in Switzerland?

Hachfeld A, Darling K, Calmy A, Ledergerber B, Weber R, Battegay M, Wissel K, Di Benedetto C, Fux CA, Tarr PE, Kouyos R, Ruggia LS, Furrer HJ, Wandeler G; Swiss HIV Cohort Study.

HIV Med. 2019 Jul;20(6):418-423. doi: 10.1111/hiv.12727. Epub 2019 May 6.


Sonography to Rule Out Tuberculosis in Sub-Saharan Africa: A Prospective Observational Study.

Ndege R, Weisser M, Elzi L, Diggelmann F, Bani F, Gingo W, Sikalengo G, Mapesi H, Mchomvu E, Kamwela L, Mnzava D, Battegay M, Reither K, Paris DH, Rohacek M.

Open Forum Infect Dis. 2019 Apr 25;6(4):ofz154. doi: 10.1093/ofid/ofz154. eCollection 2019 Apr.


The rate of mother-to-child transmission of antiretroviral drug-resistant HIV strains is low in the Swiss Mother and Child HIV Cohort Study.

Compagno F, Naegele K, Kahlert CR, Hösli I, Aebi-Popp K, Martinez de Tejada B, Paioni P, Yerly S, Böni J, Battegay M, Rudin C, Hirsch HH, Swiss Hiv Cohort Study.

Swiss Med Wkly. 2019 Apr 4;149:w20059. doi: 10.4414/smw.2019.20059. eCollection 2019 Mar 25.


Age-related comorbidities and mortality in people living with HIV in rural Tanzania.

Albrecht S, Franzeck FC, Mapesi H, Hatz C, Kalinjuma AV, Glass TR, Mnzava D, Letang E, Paris DH, Battegay M, Weisser M; KIULARCO Study Group.

AIDS. 2019 May 1;33(6):1031-1041. doi: 10.1097/QAD.0000000000002171.


A Systematic Phylogenetic Approach to Study the Interaction of HIV-1 With Coinfections, Noncommunicable Diseases, and Opportunistic Diseases.

Kusejko K, Bachmann N, Chaudron SE, Nguyen H, Braun DL, Hampel B, Battegay M, Bernasconi E, Calmy A, Cavassini M, Hoffmann M, Böni J, Yerly S, Klimkait T, Perreau M, Rauch A, Günthard HF, Kouyos RD; Swiss HIV Cohort Study .

J Infect Dis. 2019 Jun 19;220(2):244-253. doi: 10.1093/infdis/jiz093.


Viral Diversity Based on Next-Generation Sequencing of HIV-1 Provides Precise Estimates of Infection Recency and Time Since Infection.

Carlisle LA, Turk T, Kusejko K, Metzner KJ, Leemann C, Schenkel CD, Bachmann N, Posada S, Beerenwinkel N, Böni J, Yerly S, Klimkait T, Perreau M, Braun DL, Rauch A, Calmy A, Cavassini M, Battegay M, Vernazza P, Bernasconi E, Günthard HF, Kouyos RD; Swiss HIV Cohort Study .

J Infect Dis. 2019 Jun 19;220(2):254-265. doi: 10.1093/infdis/jiz094.


High Mortality of Non-Fournier Necrotizing Fasciitis With Enterobacteriales: Time to Rethink Classification?

Kuehl R, Tschudin-Sutter S, Siegemund M, Marsch S, Battegay M, Wetterauer C, Seifert HH, Schaefer DJ, Erb S, Egli A.

Clin Infect Dis. 2019 Jun 18;69(1):147-150. doi: 10.1093/cid/ciy1011.


Introduction to Machine Learning in Digital Healthcare Epidemiology.

Roth JA, Battegay M, Juchler F, Vogt JE, Widmer AF.

Infect Control Hosp Epidemiol. 2018 Dec;39(12):1457-1462. doi: 10.1017/ice.2018.265. Epub 2018 Nov 5. Review.


Frequent Door Openings During Cardiac Surgery Are Associated With Increased Risk for Surgical Site Infection: A Prospective Observational Study.

Roth JA, Juchler F, Dangel M, Eckstein FS, Battegay M, Widmer AF.

Clin Infect Dis. 2019 Jul 2;69(2):290-294. doi: 10.1093/cid/ciy879.


Inferring the age difference in HIV transmission pairs by applying phylogenetic methods on the HIV transmission network of the Swiss HIV Cohort Study.

Kusejko K, Kadelka C, Marzel A, Battegay M, Bernasconi E, Calmy A, Cavassini M, Hoffmann M, Böni J, Yerly S, Klimkait T, Perreau M, Rauch A, Günthard HF, Kouyos RD; Swiss HIV Cohort Study .

Virus Evol. 2018 Sep 18;4(2):vey024. doi: 10.1093/ve/vey024. eCollection 2018 Jul. Review.


Tracing HIV-1 strains that imprint broadly neutralizing antibody responses.

Kouyos RD, Rusert P, Kadelka C, Huber M, Marzel A, Ebner H, Schanz M, Liechti T, Friedrich N, Braun DL, Scherrer AU, Weber J, Uhr T, Baumann NS, Leemann C, Kuster H, Chave JP, Cavassini M, Bernasconi E, Hoffmann M, Calmy A, Battegay M, Rauch A, Yerly S, Aubert V, Klimkait T, Böni J, Metzner KJ, Günthard HF, Trkola A; Swiss HIV Cohort Study.

Nature. 2018 Sep;561(7723):406-410. doi: 10.1038/s41586-018-0517-0. Epub 2018 Sep 10.


Lipodystrophy Increases the Risk of CKD Development in HIV-Positive Patients in Switzerland: The LIPOKID Study.

Bouatou Y, Gayet Ageron A, Bernasconi E, Battegay M, Hoffmann M, Staehelin C, Merz L, Kovari H, Fux C, de Seigneux S, Calmy A; Swiss HIV Cohort Study.

Kidney Int Rep. 2018 May 8;3(5):1089-1099. doi: 10.1016/j.ekir.2018.04.014. eCollection 2018 Sep.


Plea for Standardized Reporting and Justification of Propensity Score Methods.

Roth JA, Juchler F, Widmer AF, Battegay M.

Clin Infect Dis. 2019 Feb 1;68(4):710-711. doi: 10.1093/cid/ciy700. No abstract available.


Costs versus earnings in colon surgery and coronary artery bypass grafting under a prospective payment system: Sufficient financial incentives to reduce surgical site infections?

Juchler F, Roth JA, Schweiger A, Dangel M, Gugliotta M, Battegay M, Eckstein FS, Kettelhack C, Abshagen C, Hug BL, Boyce JM, Widmer AF.

Infect Control Hosp Epidemiol. 2018 Oct;39(10):1246-1249. doi: 10.1017/ice.2018.179. Epub 2018 Aug 22.


Repository Describing an Aging Population to Inform Physiologically Based Pharmacokinetic Models Considering Anatomical, Physiological, and Biological Age-Dependent Changes.

Stader F, Siccardi M, Battegay M, Kinvig H, Penny MA, Marzolini C.

Clin Pharmacokinet. 2019 Apr;58(4):483-501. doi: 10.1007/s40262-018-0709-7.


Population-based outcome analysis of diffuse large B-cell lymphoma in people living with HIV infection and competent individuals.

Conconi A, Zucca E, Margiotta-Casaluci G, Darling K, Hasse B, Battegay M, Staehelin C, Novak U, Schmid P, Scherrer A, Dirnhofer S, Kwee I, Nassi L, Cavalli F, Gaidano G, Bertoni F, Bernasconi E; Swiss HIV Cohort study (SHCS).

Hematol Oncol. 2018 Dec;36(5):757-764. doi: 10.1002/hon.2536. Epub 2018 Aug 16.


Using dried blood spots to facilitate therapeutic drug monitoring of antiretroviral drugs in resource-poor regions.

Duthaler U, Berger B, Erb S, Battegay M, Letang E, Gaugler S, Natamatungiro A, Mnzava D, Donzelli M, Krähenbühl S, Haschke M.

J Antimicrob Chemother. 2018 Oct 1;73(10):2729-2737. doi: 10.1093/jac/dky254.


Quantifying the drivers of HIV transmission and prevention in men who have sex with men: a population model-based analysis in Switzerland.

Kusejko K, Marzel A, Hampel B, Bachmann N, Nguyen H, Fehr J, Braun DL, Battegay M, Bernasconi E, Calmy A, Cavassini M, Hoffmann M, Böni J, Yerly S, Klimkait T, Perreau M, Rauch A, Günthard HF, Kouyos RD; Swiss HIV Cohort Study.

HIV Med. 2018 Nov;19(10):688-697. doi: 10.1111/hiv.12660. Epub 2018 Jul 26.


Boosted darunavir, emtricitabine and tenofovir pharmacokinetics in sthe early and late postgastric bypass surgery periods.

Baettig V, Courlet P, Delko T, Battegay M, Marzolini C.

AIDS. 2018 Aug 24;32(13):1903-1905. doi: 10.1097/QAD.0000000000001913. No abstract available.


Cost Estimates for Human Immunodeficiency Virus (HIV) Care and Patient Characteristics for Health Resource Use From Linkage of Claims Data With the Swiss HIV Cohort Study.

Leon-Reyes S, Schäfer J, Früh M, Schwenkglenks M, Reich O, Schmidlin K, Staehelin C, Battegay M, Cavassini M, Hasse B, Bernasconi E, Calmy A, Hoffmann M, Schoeni-Affolter F, Zhao H, Bucher HC.

Clin Infect Dis. 2019 Feb 15;68(5):827-833. doi: 10.1093/cid/ciy564.


Distinct, IgG1-driven antibody response landscapes demarcate individuals with broadly HIV-1 neutralizing activity.

Kadelka C, Liechti T, Ebner H, Schanz M, Rusert P, Friedrich N, Stiegeler E, Braun DL, Huber M, Scherrer AU, Weber J, Uhr T, Kuster H, Misselwitz B, Cavassini M, Bernasconi E, Hoffmann M, Calmy A, Battegay M, Rauch A, Yerly S, Aubert V, Klimkait T, Böni J, Kouyos RD, Günthard HF, Trkola A; Swiss HIV Cohort Study.

J Exp Med. 2018 Jun 4;215(6):1589-1608. doi: 10.1084/jem.20180246. Epub 2018 May 24.


Brief Report: No HIV Transmission From Virally Suppressed Mothers During Breastfeeding in Rural Tanzania.

Luoga E, Vanobberghen F, Bircher R, Nyuri A, Ntamatungiro AJ, Mnzava D, Mollel GJ, Letang E, Battegay M, Weisser M, Gamell A.

J Acquir Immune Defic Syndr. 2018 Sep 1;79(1):e17-e20. doi: 10.1097/QAI.0000000000001758.


Prevalence and Evolution of Renal Impairment in People Living With HIV in Rural Tanzania.

Mapesi H, Kalinjuma AV, Ngerecha A, Franzeck F, Hatz C, Tanner M, Mayr M, Furrer H, Battegay M, Letang E, Weisser M, Glass TR; KIULARCO Study Group .

Open Forum Infect Dis. 2018 Apr 6;5(4):ofy072. doi: 10.1093/ofid/ofy072. eCollection 2018 Apr.


Analysis of Clinical Drug-Drug Interaction Data To Predict Magnitudes of Uncharacterized Interactions between Antiretroviral Drugs and Comedications.

Stader F, Kinvig H, Battegay M, Khoo S, Owen A, Siccardi M, Marzolini C.

Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e00717-18. doi: 10.1128/AAC.00717-18. Print 2018 Jul.


Highlights of the 2017 European AIDS Clinical Society (EACS) Guidelines for the treatment of adult HIV-positive persons version 9.0.

Ryom L, Boesecke C, Bracchi M, Ambrosioni J, Pozniak A, Arribas J, Behrens G, Mallon P, Puoti M, Rauch A, Miro JM, Kirk O, Marzolini C, Lundgren JD, Battegay M; EACS Governing Board.

HIV Med. 2018 May;19(5):309-315. doi: 10.1111/hiv.12600. Epub 2018 Mar 1.


Differences in Virological and Immunological Risk Factors for Non-Hodgkin and Hodgkin Lymphoma.

Shepherd L, Ryom L, Law M, Hatleberg CI, de Wit S, Monforte AD, Battegay M, Phillips A, Bonnet F, Reiss P, Pradier C, Grulich A, Sabin C, Lundgren J, Mocroft A.

J Natl Cancer Inst. 2018 Jun 1;110(6):598-607. doi: 10.1093/jnci/djx249.


Direct Costs of a Contact Isolation Day: A Prospective Cost Analysis at a Swiss University Hospital.

Roth JA, Hornung-Winter C, Radicke I, Hug BL, Biedert M, Abshagen C, Battegay M, Widmer AF.

Infect Control Hosp Epidemiol. 2018 Jan;39(1):101-103. doi: 10.1017/ice.2017.258. Epub 2017 Dec 18.


Digging Out the Evidence-How Strong Is the IDSA Recommendation Against Antibiotic Prophylaxis in Basilar Skull Fracture and Cerebrospinal Fluid Leakage?

Kuehl R, Büchler A, Widmer AF, Battegay M.

Clin Infect Dis. 2018 Apr 3;66(8):1319-1320. doi: 10.1093/cid/cix984. No abstract available.


European AIDS Clinical Society Second Standard of Care Meeting, Brussels 16-17 November 2016: a summary.

De Wit S, Battegay M, D'Arminio Monforte A, Lundgren JD, Oprea C, Antinori A, Bhagani S, Fätkenheuer G, Friis-Moller N, Furrer H, Mussini C; European AIDS Clinical Society.

HIV Med. 2018 Feb;19(2):77-80. doi: 10.1111/hiv.12559. Epub 2017 Oct 27.


Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T-Cell Decline, and Per-Parasite Pathogenicity.

Bertels F, Marzel A, Leventhal G, Mitov V, Fellay J, Günthard HF, Böni J, Yerly S, Klimkait T, Aubert V, Battegay M, Rauch A, Cavassini M, Calmy A, Bernasconi E, Schmid P, Scherrer AU, Müller V, Bonhoeffer S, Kouyos R, Regoes RR; Swiss HIV Cohort Study.

Mol Biol Evol. 2018 Jan 1;35(1):27-37. doi: 10.1093/molbev/msx246.


Previous exposure in a high-risk area for travellers' diarrhoea within the past year is associated with a significant protective effect for travellers' diarrhoea: a prospective observational cohort study in travellers to South Asia.

Kuenzli E, Juergensen D, Kling K, Jaeger VK, DeCrom S, Steffen R, Widmer AF, Battegay M, Hatz C, Neumayr A.

J Travel Med. 2017 Sep 1;24(5). doi: 10.1093/jtm/tax056.


Assessing the danger of self-sustained HIV epidemics in heterosexuals by population based phylogenetic cluster analysis.

Turk T, Bachmann N, Kadelka C, Böni J, Yerly S, Aubert V, Klimkait T, Battegay M, Bernasconi E, Calmy A, Cavassini M, Furrer H, Hoffmann M, Günthard HF, Kouyos RD; Swiss HIV Cohort Study, Aubert V, Battegay M, Bernasconi E, Böni J, Braun DL, Bucher HC, Calmy A, Cavassini M, Ciuffi A, Dollenmaier G, Egger M, Elzi L, Fehr J, Fellay J, Furrer H, Fux CA, Günthard HF, Haerry D, Hasse B, Hirsch HH, Hoffmann M, Hösli I, Kahlert C, Kaiser L, Keiser O, Klimkait T, Kouyos RD, Kovari H, Ledergerber B, Martinetti G, Martinez de Tejada B, Marzolini C, Metzner KJ, Müller N, Nicca D, Pantaleo G, Paioni P, Rauch A, Rudin C, Scherrer AU, Schmid P, Speck R, Stöckle M, Tarr P, Trkola A, Vernazza P, Wandeler G, Weber R, Yerly S.

Elife. 2017 Sep 12;6. pii: e28721. doi: 10.7554/eLife.28721.


Specificity of two HIV screening tests detecting simultaneously HIV-1 p24 antigen and antibodies to HIV-1 and -2.

Blaich A, Buser A, Stöckle M, Gehringer C, Hirsch HH, Battegay M, Klimkait T, Frei R.

J Virol Methods. 2017 Nov;249:143-146. doi: 10.1016/j.jviromet.2017.09.005. Epub 2017 Sep 8.


Value of the Pitt Bacteraemia Score to predict short-term mortality in Staphylococcus aureus bloodstream infection: a validation study.

Roth JA, Tschudin-Sutter S, Dangel M, Frei R, Battegay M, Widmer AF.

Swiss Med Wkly. 2017 Aug 10;147:w14482. doi: 10.4414/smw.2017.14482. eCollection 2017.


A decade of HIV care in rural Tanzania: Trends in clinical outcomes and impact of clinic optimisation in an open, prospective cohort.

Vanobberghen F, Letang E, Gamell A, Mnzava DK, Faini D, Luwanda LB, Mapesi H, Mwamelo K, Sikalengo G, Tanner M, Hatz C, Furrer H, Battegay M, Glass TR; KIULARCO Study Group.

PLoS One. 2017 Jul 18;12(7):e0180983. doi: 10.1371/journal.pone.0180983. eCollection 2017.


Prevention of mother-to-child transmission of HIV Option B+ cascade in rural Tanzania: The One Stop Clinic model.

Gamell A, Luwanda LB, Kalinjuma AV, Samson L, Ntamatungiro AJ, Weisser M, Gingo W, Tanner M, Hatz C, Letang E, Battegay M; KIULARCO Study Group.

PLoS One. 2017 Jul 12;12(7):e0181096. doi: 10.1371/journal.pone.0181096. eCollection 2017.


Cohort profile: The Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) - A prospective HIV cohort in rural Tanzania.

Letang E, Kalinjuma AV, Glass TR, Gamell A, Mapesi H, Sikalengo GR, Luwanda LB, Mnzava D, Ntamatungiro AJ, Ndaki R, Francis G, Vanobberghen F, Furrer H, Klimkait T, Felger I, Tanner M, Hatz C, Weisser M, Battegay M, Kiularco Study Group.

Swiss Med Wkly. 2017 Jul 4;147:w14485. doi: 10.4414/smw.2017.14485. eCollection 2017.


Adverse events of raltegravir and dolutegravir.

Elzi L, Erb S, Furrer H, Cavassini M, Calmy A, Vernazza P, Günthard H, Bernasconi E, Battegay M; Swiss HIV Cohort Study Group.

AIDS. 2017 Aug 24;31(13):1853-1858. doi: 10.1097/QAD.0000000000001590.

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