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Items: 1 to 50 of 161

1.

VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy.

Onions K, Gamez M, Buckner NR, Baker SL, Betteridge KB, Desideri S, Dallyn BP, Ramnath R, Neal CR, Farmer LK, Mathieson PW, Gnudi L, Alitalo K, Bates DO, Salmon AHJ, Welsh GI, Satchell SC, Foster RR.

Diabetes. 2018 Nov 2. pii: db180045. doi: 10.2337/db18-0045. [Epub ahead of print]

PMID:
30389746
2.

Novel hemodynamic structures in the human glomerulus.

Neal CR, Arkill KP, Bell JS, Betteridge KB, Bates DO, Winlove CP, Salmon AHJ, Harper SJ.

Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1370-F1384. doi: 10.1152/ajprenal.00566.2017. Epub 2018 Jun 20.

3.

BDNF (Brain-Derived Neurotrophic Factor) Promotes Embryonic Stem Cells Differentiation to Endothelial Cells Via a Molecular Pathway, Including MicroRNA-214, EZH2 (Enhancer of Zeste Homolog 2), and eNOS (Endothelial Nitric Oxide Synthase).

Descamps B, Saif J, Benest AV, Biglino G, Bates DO, Chamorro-Jorganes A, Emanueli C.

Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2117-2125. doi: 10.1161/ATVBAHA.118.311400.

PMID:
30354255
4.

Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators.

Bates DO, Beazley-Long N, Benest AV, Ye X, Ved N, Hulse RP, Barratt S, Machado MJ, Donaldson LF, Harper SJ, Peiris-Pages M, Tortonese DJ, Oltean S, Foster RR.

Compr Physiol. 2018 Jun 18;8(3):955-979. doi: 10.1002/cphy.c170015.

PMID:
29978898
5.

Sensory neuronal sensitisation occurs through HMGB-1-RAGE and TRPV1 in high-glucose conditions.

Bestall SM, Hulse RP, Blackley Z, Swift M, Ved N, Paton K, Beazley-Long N, Bates DO, Donaldson LF.

J Cell Sci. 2018 Jul 26;131(14). pii: jcs215939. doi: 10.1242/jcs.215939.

6.

NOVEL HAEMODYNAMIC STRUCTURES IN THE HUMAN GLOMERULUS.

Neal CR, Arkill K, Bell JS, Betteridge KB, Bates DO, Winlove CP, Salmon AH, Harper SJ.

Am J Physiol Renal Physiol. 2018 Jun 20. doi: 10.1152/ajprenal.00566.2017. [Epub ahead of print]

PMID:
29923763
7.

Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain.

Ved N, Da Vitoria Lobo ME, Bestall SM, L Vidueira C, Beazley-Long N, Ballmer-Hofer K, Hirashima M, Bates DO, Donaldson LF, Hulse RP.

J Physiol. 2018 Aug;596(16):3675-3693. doi: 10.1113/JP275067. Epub 2018 Jul 11.

8.

Consensus guidelines for the use and interpretation of angiogenesis assays.

Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW.

Angiogenesis. 2018 May 15. doi: 10.1007/s10456-018-9613-x. [Epub ahead of print] Review.

9.

VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis.

Beazley-Long N, Moss CE, Ashby WR, Bestall SM, Almahasneh F, Durrant AM, Benest AV, Blackley Z, Ballmer-Hofer K, Hirashima M, Hulse RP, Bates DO, Donaldson LF.

Brain Behav Immun. 2018 Mar 14. pii: S0889-1591(18)30060-6. doi: 10.1016/j.bbi.2018.03.012. [Epub ahead of print]

10.

Vascular Endothelial Growth Factor-A165b Restores Normal Glomerular Water Permeability in a Diphtheria-Toxin Mouse Model of Glomerular Injury.

Stevens M, Neal CR, Salmon AHJ, Bates DO, Harper SJ, Oltean S.

Nephron. 2018;139(1):51-62. doi: 10.1159/000485664. Epub 2018 Jan 26.

11.

Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF).

Barratt SL, Blythe T, Ourradi K, Jarrett C, Welsh GI, Bates DO, Millar AB.

Respir Res. 2018 Jan 15;19(1):9. doi: 10.1186/s12931-017-0711-x.

12.

Sulfated galactans from the red seaweed Gracilaria fisheri exerts anti-migration effect on cholangiocarcinoma cells.

Sae-Lao T, Luplertlop N, Janvilisri T, Tohtong R, Bates DO, Wongprasert K.

Phytomedicine. 2017 Dec 1;36:59-67. doi: 10.1016/j.phymed.2017.09.014. Epub 2017 Sep 28.

PMID:
29157829
13.
14.

Differential Expression of VEGF-Axxx Isoforms Is Critical for Development of Pulmonary Fibrosis.

Barratt SL, Blythe T, Jarrett C, Ourradi K, Shelley-Fraser G, Day MJ, Qiu Y, Harper S, Maher TM, Oltean S, Hames TJ, Scotton CJ, Welsh GI, Bates DO, Millar AB.

Am J Respir Crit Care Med. 2017 Aug 15;196(4):479-493. doi: 10.1164/rccm.201603-0568OC.

15.

The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1.

Pruszko M, Milano E, Forcato M, Donzelli S, Ganci F, Di Agostino S, De Panfilis S, Fazi F, Bates DO, Bicciato S, Zylicz M, Zylicz A, Blandino G, Fontemaggi G.

EMBO Rep. 2017 Aug;18(8):1331-1351. doi: 10.15252/embr.201643370. Epub 2017 Jun 26.

16.

Can the co-dependence of the immune system and angiogenesis facilitate pharmacological targeting of tumours?

Mortara L, Benest AV, Bates DO, Noonan DM.

Curr Opin Pharmacol. 2017 Aug;35:66-74. doi: 10.1016/j.coph.2017.05.009. Epub 2017 Jun 14. Review.

PMID:
28623714
17.

VEGF-A165 b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF-A splice isoforms from the kidney.

Stevens M, Neal CR, Salmon AHJ, Bates DO, Harper SJ, Oltean S.

J Physiol. 2017 Oct 1;595(19):6281-6298. doi: 10.1113/JP274481. Epub 2017 Jul 3.

18.

Sialic acids regulate microvessel permeability, revealed by novel in vivo studies of endothelial glycocalyx structure and function.

Betteridge KB, Arkill KP, Neal CR, Harper SJ, Foster RR, Satchell SC, Bates DO, Salmon AHJ.

J Physiol. 2017 Aug 1;595(15):5015-5035. doi: 10.1113/JP274167.

19.

Correction: LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma.

Vieira GC, Chockalingam S, Melegh Z, Greenhough A, Malik S, Szemes M, Park JH, Kaidi A, Zhou L, Catchpoole D, Morgan R, Bates DO, Gabb PJ, Malik K.

Oncotarget. 2017 May 9;8(19):32381. doi: 10.18632/oncotarget.17685. No abstract available.

20.

Sulfated Galactans from Red Seaweed Gracilaria fisheri Target EGFR and Inhibit Cholangiocarcinoma Cell Proliferation.

Sae-Lao T, Tohtong R, Bates DO, Wongprasert K.

Am J Chin Med. 2017;45(3):615-633. doi: 10.1142/S0192415X17500367. Epub 2017 Apr 6.

PMID:
28385079
21.

Vascular endothelial growth factor-A165b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina.

Ved N, Hulse RP, Bestall SM, Donaldson LF, Bainbridge JW, Bates DO.

Clin Sci (Lond). 2017 Jun 1;131(12):1225-1243. doi: 10.1042/CS20170102. Epub 2017 Mar 24.

22.

Mechanisms regulating angiogenesis underlie seasonal control of pituitary function.

Castle-Miller J, Bates DO, Tortonese DJ.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2514-E2523. doi: 10.1073/pnas.1618917114. Epub 2017 Mar 7.

23.

Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.

Batson J, Toop HD, Redondo C, Babaei-Jadidi R, Chaikuad A, Wearmouth SF, Gibbons B, Allen C, Tallant C, Zhang J, Du C, Hancox JC, Hawtrey T, Da Rocha J, Griffith R, Knapp S, Bates DO, Morris JC.

ACS Chem Biol. 2017 Mar 17;12(3):825-832. doi: 10.1021/acschembio.6b01048. Epub 2017 Feb 6.

24.

Pharmacology of Modulators of Alternative Splicing.

Bates DO, Morris JC, Oltean S, Donaldson LF.

Pharmacol Rev. 2017 Jan;69(1):63-79. doi: 10.1124/pr.115.011239. Review.

25.

Differential regulation of blood flow-induced neovascularization and mural cell recruitment by vascular endothelial growth factor and angiopoietin signalling.

Stone OA, Carter JG, Lin PC, Paleolog E, Machado MJ, Bates DO.

J Physiol. 2017 Mar 1;595(5):1575-1591. doi: 10.1113/JP273430. Epub 2017 Feb 2.

26.

The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain.

Hulse RP, Drake RA, Bates DO, Donaldson LF.

Neurobiol Dis. 2016 Dec;96:186-200. doi: 10.1016/j.nbd.2016.09.009. Epub 2016 Sep 9.

27.

Direct detection and measurement of wall shear stress using a filamentous bio-nanoparticle.

Lobo DP, Wemyss AM, Smith DJ, Straube A, Betteridge KB, Salmon AH, Foster RR, Elhegni HE, Satchell SC, Little HA, Pacheco-Gómez R, Simmons MJ, Hicks MR, Bates DO, Rodger A, Dafforn TR, Arkill KP.

Nano Res. 2015 Oct;8(10):3307-3315.

28.

Measurement of Angiogenesis, Arteriolargenesis, and Lymphangiogenesis Phenotypes by Use of Two-Dimensional Mesenteric Angiogenesis Assay.

Benest AV, Bates DO.

Methods Mol Biol. 2016;1430:345-54. doi: 10.1007/978-1-4939-3628-1_24.

PMID:
27172966
29.

Models of Oxygen Induced Retinopathy in Rodents.

Gammons MV, Bates DO.

Methods Mol Biol. 2016;1430:317-32. doi: 10.1007/978-1-4939-3628-1_22.

PMID:
27172964
30.

Altered ratios of pro- and anti-angiogenic VEGF-A variants and pericyte expression of DLL4 disrupt vascular maturation in infantile haemangioma.

Ye X, Abou-Rayyah Y, Bischoff J, Ritchie A, Sebire NJ, Watts P, Churchill AJ, Bates DO.

J Pathol. 2016 Jun;239(2):139-51. doi: 10.1002/path.4715.

31.

Erratum to: South African Herbal Extracts as Potential Chemopreventive Agents: Screening for Anticancer Splicing Activity.

Dlamini Z, Mbita Z, Bates DO.

Methods Mol Biol. 2016;1379:E1. doi: 10.1007/978-1-4939-3191-0_19. No abstract available.

PMID:
26842946
32.
33.

LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma.

Vieira GC, Chockalingam S, Melegh Z, Greenhough A, Malik S, Szemes M, Park JH, Kaidi A, Zhou L, Catchpoole D, Morgan R, Bates DO, Gabb PD, Malik K.

Oncotarget. 2015 Nov 24;6(37):40053-67. doi: 10.18632/oncotarget.5548. Erratum in: Oncotarget. 2017 May 9;8(19):32381.

34.

Circulating levels of anti-angiogenic VEGF-A isoform (VEGF-Axxxb) in colorectal cancer patients predicts tumour VEGF-A ratios.

Bunni J, Shelley-Fraser G, Stevenson K, Oltean S, Salmon A, Harper SJ, Carter JG, Bates DO.

Am J Cancer Res. 2015 May 15;5(6):2083-9. eCollection 2015.

35.

Vascular endothelial growth factor-A165b prevents diabetic neuropathic pain and sensory neuronal degeneration.

Hulse RP, Beazley-Long N, Ved N, Bestall SM, Riaz H, Singhal P, Ballmer Hofer K, Harper SJ, Bates DO, Donaldson LF.

Clin Sci (Lond). 2015 Oct 1;129(8):741-56. doi: 10.1042/CS20150124.

PMID:
26201024
36.

IL-4 regulates specific Arg-1(+) macrophage sFlt-1-mediated inhibition of angiogenesis.

Wu WK, Georgiadis A, Copland DA, Liyanage S, Luhmann UF, Robbie SJ, Liu J, Wu J, Bainbridge JW, Bates DO, Ali RR, Nicholson LB, Dick AD.

Am J Pathol. 2015 Aug;185(8):2324-35. doi: 10.1016/j.ajpath.2015.04.013. Epub 2015 Jun 13.

PMID:
26079814
37.

Regulation of vascular endothelial growth factor in prostate cancer.

de Brot S, Ntekim A, Cardenas R, James V, Allegrucci C, Heery DM, Bates DO, Ødum N, Persson JL, Mongan NP.

Endocr Relat Cancer. 2015 Jun;22(3):R107-23. doi: 10.1530/ERC-15-0123. Epub 2015 Apr 13. Review.

PMID:
25870249
38.

Novel mechanisms of resistance to vemurafenib in melanoma - V600E B-Raf reversion and switching VEGF-A splice isoform expression.

Beazley-Long N, Gaston K, Harper SJ, Orlando A, Bates DO.

Am J Cancer Res. 2014 Dec 15;5(1):433-41. eCollection 2015.

39.

Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy.

Oltean S, Qiu Y, Ferguson JK, Stevens M, Neal C, Russell A, Kaura A, Arkill KP, Harris K, Symonds C, Lacey K, Wijeyaratne L, Gammons M, Wylie E, Hulse RP, Alsop C, Cope G, Damodaran G, Betteridge KB, Ramnath R, Satchell SC, Foster RR, Ballmer-Hofer K, Donaldson LF, Barratt J, Baelde HJ, Harper SJ, Bates DO, Salmon AH.

J Am Soc Nephrol. 2015 Aug;26(8):1889-904. doi: 10.1681/ASN.2014040350. Epub 2014 Dec 26.

40.

Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer.

Mavrou A, Brakspear K, Hamdollah-Zadeh M, Damodaran G, Babaei-Jadidi R, Oxley J, Gillatt DA, Ladomery MR, Harper SJ, Bates DO, Oltean S.

Oncogene. 2015 Aug 13;34(33):4311-9. doi: 10.1038/onc.2014.360. Epub 2014 Nov 10.

41.

An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease.

Kikuchi R, Nakamura K, MacLauchlan S, Ngo DT, Shimizu I, Fuster JJ, Katanasaka Y, Yoshida S, Qiu Y, Yamaguchi TP, Matsushita T, Murohara T, Gokce N, Bates DO, Hamburg NM, Walsh K.

Nat Med. 2014 Dec;20(12):1464-71. doi: 10.1038/nm.3703. Epub 2014 Nov 2.

42.

The carboxyl terminus of VEGF-A is a potential target for anti-angiogenic therapy.

Carter JG, Gammons MV, Damodaran G, Churchill AJ, Harper SJ, Bates DO.

Angiogenesis. 2015 Jan;18(1):23-30. doi: 10.1007/s10456-014-9444-3. Epub 2014 Oct 2.

43.

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance.

Hamdollah Zadeh MA, Amin EM, Hoareau-Aveilla C, Domingo E, Symonds KE, Ye X, Heesom KJ, Salmon A, D'Silva O, Betteridge KB, Williams AC, Kerr DJ, Salmon AH, Oltean S, Midgley RS, Ladomery MR, Harper SJ, Varey AH, Bates DO.

Mol Oncol. 2015 Jan;9(1):167-78. doi: 10.1016/j.molonc.2014.07.017. Epub 2014 Aug 20.

44.

Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia.

Hulse RP, Beazley-Long N, Hua J, Kennedy H, Prager J, Bevan H, Qiu Y, Fernandes ES, Gammons MV, Ballmer-Hofer K, Gittenberger de Groot AC, Churchill AJ, Harper SJ, Brain SD, Bates DO, Donaldson LF.

Neurobiol Dis. 2014 Nov;71:245-59. doi: 10.1016/j.nbd.2014.08.012. Epub 2014 Aug 21.

45.

The role of VEGF-A165b in trophoblast survival.

Bills VL, Hamdollah-Zadeh M, Soothill PW, Harper SJ, Bates DO.

BMC Pregnancy Childbirth. 2014 Aug 15;14:278. doi: 10.1186/1471-2393-14-278.

46.

Antiangiogenic actions of vascular endothelial growth factor-A165b, an inhibitory isoform of vascular endothelial growth factor-A, in human obesity.

Ngo DT, Farb MG, Kikuchi R, Karki S, Tiwari S, Bigornia SJ, Bates DO, LaValley MP, Hamburg NM, Vita JA, Hess DT, Walsh K, Gokce N.

Circulation. 2014 Sep 23;130(13):1072-80. doi: 10.1161/CIRCULATIONAHA.113.008171. Epub 2014 Aug 12.

47.

Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanoma.

Gammons MV, Lucas R, Dean R, Coupland SE, Oltean S, Bates DO.

Br J Cancer. 2014 Jul 29;111(3):477-85. doi: 10.1038/bjc.2014.342. Epub 2014 Jul 10.

48.

TNF-α-induced ICAM-1 expression and monocyte adhesion in human RPE cells is mediated in part through autocrine VEGF stimulation.

Thichanpiang P, Harper SJ, Wongprasert K, Bates DO.

Mol Vis. 2014 Jun 10;20:781-9. eCollection 2014.

49.

Resolution of the three dimensional structure of components of the glomerular filtration barrier.

Arkill KP, Qvortrup K, Starborg T, Mantell JM, Knupp C, Michel CC, Harper SJ, Salmon AH, Squire JM, Bates DO, Neal CR.

BMC Nephrol. 2014 Feb 1;15:24. doi: 10.1186/1471-2369-15-24.

50.

Hallmarks of alternative splicing in cancer.

Oltean S, Bates DO.

Oncogene. 2014 Nov 13;33(46):5311-8. doi: 10.1038/onc.2013.533. Epub 2013 Dec 16. Review.

PMID:
24336324

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