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Items: 46

1.

Dimethylaminoparthenolide reduces the incidence of dysplasia and ameliorates a wasting syndrome in HPV16-transgenic mice.

Santos JMO, Moreira-Pais A, Neto T, Peixoto da Silva S, Oliveira PA, Ferreira R, Mendes J, Bastos MMSM, Lopes C, Casaca F, Silva S, Sweeney C, Medeiros R, Gil da Costa RM.

Drug Dev Res. 2019 Jul 13. doi: 10.1002/ddr.21565. [Epub ahead of print]

PMID:
31301186
2.

Repurposing strategies for Chagas disease therapy: the effect of imatinib and derivatives against Trypanosoma cruzi.

Simões-Silva MR, De Araújo JS, Peres RB, Da Silva PB, Batista MM, De Azevedo LD, Bastos MM, Bahia MT, Boechat N, Soeiro MNC.

Parasitology. 2019 Jul;146(8):1006-1012. doi: 10.1017/S0031182019000234. Epub 2019 Mar 12.

PMID:
30859917
3.

Yellow fever virus is susceptible to sofosbuvir both in vitro and in vivo.

de Freitas CS, Higa LM, Sacramento CQ, Ferreira AC, Reis PA, Delvecchio R, Monteiro FL, Barbosa-Lima G, James Westgarth H, Vieira YR, Mattos M, Rocha N, Hoelz LVB, Leme RPP, Bastos MM, Rodrigues GOL, Lopes CEM, Queiroz-Junior CM, Lima CX, Costa VV, Teixeira MM, Bozza FA, Bozza PT, Boechat N, Tanuri A, Souza TML.

PLoS Negl Trop Dis. 2019 Jan 30;13(1):e0007072. doi: 10.1371/journal.pntd.0007072. eCollection 2019 Jan.

4.

Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication.

Ferreira AC, Reis PA, de Freitas CS, Sacramento CQ, Villas Bôas Hoelz L, Bastos MM, Mattos M, Rocha N, Gomes de Azevedo Quintanilha I, da Silva Gouveia Pedrosa C, Rocha Quintino Souza L, Correia Loiola E, Trindade P, Rangel Vieira Y, Barbosa-Lima G, de Castro Faria Neto HC, Boechat N, Rehen SK, Brüning K, Bozza FA, Bozza PT, Souza TML.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01389-18. doi: 10.1128/AAC.01389-18. Print 2019 Feb.

5.

New Efavirenz Derivatives and 1,2,3-Triazolyl-phosphonates as Inhibitors of Reverse Transcriptase of HIV-1.

Costa CCP, Boechat N, Bastos MM, da Silva FC, Marttorelli A, Souza TML, Baptista MS, Hoelz LVB, Cafffarena ER.

Curr Top Med Chem. 2018;18(17):1494-1505. doi: 10.2174/1568026618666181029150118.

PMID:
30370848
6.

Estimating under-observation and the full size of the 2016 Zika epidemic in Rio de Janeiro.

Bastos MM, Coelho FC.

PLoS One. 2018 Oct 12;13(10):e0205001. doi: 10.1371/journal.pone.0205001. eCollection 2018.

7.

Ozone therapy prevents the onset of dysplasia in HPV16-transgenic mice-A pre-clinical efficacy and safety analysis.

Peirone C, Mestre VF, Medeiros-Fonseca B, Colaço B, Pires MJ, Martins T, Gil da Costa RM, Neuparth MJ, Medeiros R, Bastos MMSM, Marques-Magallanes JA, Oliveira PA.

Biomed Pharmacother. 2018 Aug;104:275-279. doi: 10.1016/j.biopha.2018.05.018. Epub 2018 May 25.

PMID:
29775895
8.

New 1,2,3-triazole-based analogues of benznidazole for use against Trypanosoma cruzi infection: In vitro and in vivo evaluations.

Leite DI, Fontes FV, Bastos MM, Hoelz LVB, Bianco MDCAD, de Oliveira AP, da Silva PB, da Silva CF, Batista DDGJ, da Gama ANS, Peres RB, Villar JDF, Soeiro MNC, Boechat N.

Chem Biol Drug Des. 2018 Sep;92(3):1670-1682. doi: 10.1111/cbdd.13333. Epub 2018 Jun 13.

PMID:
29745048
9.

Curcumin and Rutin Down-regulate Cyclooxygenase-2 and Reduce Tumor-associated Inflammation in HPV16-Transgenic Mice.

Moutinho MSS, Aragão S, Carmo D, Casaca F, Silva S, Ribeiro J, Sousa H, Pires I, Queiroga F, Colaço B, Medeiros R, Oliveira PA, Lopes C, Bastos MMSM, DA Costa RMG.

Anticancer Res. 2018 Mar;38(3):1461-1466.

PMID:
29491072
10.

Expression profile of microRNA-146a along HPV-induced multistep carcinogenesis: a study in HPV16 transgenic mice.

Araújo R, Santos JMO, Fernandes M, Dias F, Sousa H, Ribeiro J, Bastos MMSM, Oliveira PA, Carmo D, Casaca F, Silva S, Medeiros R, Gil da Costa RM.

J Cancer Res Clin Oncol. 2018 Feb;144(2):241-248. doi: 10.1007/s00432-017-2549-5. Epub 2017 Nov 27.

PMID:
29181576
11.

Topographic and Chemical Analysis of Reciprocating and Rotary Instruments Surface after Continuous Use.

Bastos MMB, Hanan ARA, Bastos AMB, Marques AAF, Garcia LDFR, Sponchiado EC Júnior.

Braz Dent J. 2017 Jul-Aug;28(4):461-466. doi: 10.1590/0103-6440201701528.

12.

Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice.

DA Costa RMG, Araújo R, Santos JMO, Fernandes M, Neto T, Sousa H, Ribeiro J, Bastos MMSM, Oliveira PA, Carmo D, Casaca F, Silva S, Lopes C, Medeiros R.

Anticancer Res. 2017 Jun;37(6):2913-2918.

PMID:
28551628
13.

Corrigendum: The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication.

Sacramento CQ, de Melo GR, de Freitas CS, Rocha N, Hoelz LVB, Miranda M, Fintelman-Rodrigues N, Marttorelli A, Ferreira AC, Barbosa-Lima G, Abrantes JL, Vieira YR, Bastos MM, Volotão EM, Nunes EP, Tschoeke DA, Leomil L, Loiola EC, Trindade P, Rehen SK, Bozza FA, Bozza PT, Boechat N, Thompson FL, de Filippis AMB, Brüning K, Souza TML.

Sci Rep. 2017 Apr 24;7:46772. doi: 10.1038/srep46772. No abstract available.

14.

Dysregulated expression of microRNA-150 in human papillomavirus-induced lesions of K14-HPV16 transgenic mice.

Santos JMO, Fernandes M, Araújo R, Sousa H, Ribeiro J, Bastos MMSM, Oliveira PA, Carmo D, Casaca F, Silva S, Teixeira AL, Gil da Costa RM, Medeiros R.

Life Sci. 2017 Apr 15;175:31-36. doi: 10.1016/j.lfs.2017.03.008. Epub 2017 Mar 14.

PMID:
28302562
15.

The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication.

Sacramento CQ, de Melo GR, de Freitas CS, Rocha N, Hoelz LV, Miranda M, Fintelman-Rodrigues N, Marttorelli A, Ferreira AC, Barbosa-Lima G, Abrantes JL, Vieira YR, Bastos MM, de Mello Volotão E, Nunes EP, Tschoeke DA, Leomil L, Loiola EC, Trindade P, Rehen SK, Bozza FA, Bozza PT, Boechat N, Thompson FL, de Filippis AM, Brüning K, Souza TM.

Sci Rep. 2017 Jan 18;7:40920. doi: 10.1038/srep40920. Erratum in: Sci Rep. 2017 Apr 24;7:46772.

16.

HPV16 induces a wasting syndrome in transgenic mice: Amelioration by dietary polyphenols via NF-κB inhibition.

Gil da Costa RM, Aragão S, Moutinho M, Alvarado A, Carmo D, Casaca F, Silva S, Ribeiro J, Sousa H, Ferreira R, Nogueira-Ferreira R, Pires MJ, Colaço B, Medeiros R, Venâncio C, Oliveira MM, Bastos MM, Lopes C, Oliveira PA.

Life Sci. 2017 Jan 15;169:11-19. doi: 10.1016/j.lfs.2016.10.031. Epub 2016 Nov 22.

PMID:
27888116
17.

Ptaquiloside from bracken (Pteridium spp.) inhibits tumour-infiltrating CD8+ T cells in HPV-16 transgenic mice.

Santos C, Ferreirinha P, Sousa H, Ribeiro J, Bastos MM, Neto T, Oliveira PA, Medeiros R, Vilanova M, Gil da Costa RM.

Food Chem Toxicol. 2016 Nov;97:277-285. doi: 10.1016/j.fct.2016.09.019. Epub 2016 Sep 15.

PMID:
27640346
18.

Erratum to: Assessment of postoperative pain after reciprocating or rotary NiTi instrumentation of root canals: a randomized, controlled clinical trial.

Relvas JB, Bastos MM, Marques AA, Garrido AD, Herkrath FJ, Sponchiado EC Jr.

Clin Oral Investig. 2016 Nov;20(8):1995. No abstract available.

PMID:
26911493
19.

Assessment of postoperative pain after reciprocating or rotary NiTi instrumentation of root canals: a randomized, controlled clinical trial.

Relvas JB, Bastos MM, Marques AA, Garrido AD, Sponchiado EC Jr.

Clin Oral Investig. 2016 Nov;20(8):1987-1993. Epub 2015 Dec 19. Erratum in: Clin Oral Investig. 2016 Nov;20(8):1995.

PMID:
26685850
20.

Phytochemical profiling as a solution to palliate disinfectant limitations.

Malheiro J, Gomes I, Borges A, Bastos MM, Maillard JY, Borges F, Simões M.

Biofouling. 2016 Oct;32(9):1007-16. doi: 10.1080/08927014.2016.1220550.

PMID:
27552663
21.

Oxidized Xanthan Gum and Chitosan as Natural Adhesives for Cork.

Paiva D, Gonçalves C, Vale I, Bastos MMSM, Magalhães FD.

Polymers (Basel). 2016 Jul 14;8(7). pii: E259. doi: 10.3390/polym8070259.

22.

Celecoxib promotes degranulation of CD8(+) T cells in HPV-induced lesions of K14-HPV16 transgenic mice.

Santos C, Neto T, Ferreirinha P, Sousa H, Ribeiro J, Bastos MM, Faustino-Rocha AI, Oliveira PA, Medeiros R, Vilanova M, da Costa RM.

Life Sci. 2016 Jul 15;157:67-73. doi: 10.1016/j.lfs.2016.05.040. Epub 2016 May 31.

PMID:
27259813
23.

The NFκB Signaling Pathway in Papillomavirus-induced Lesions: Friend or Foe?

DA Costa RM, Bastos MM, Medeiros R, Oliveira PA.

Anticancer Res. 2016 May;36(5):2073-83. Review.

PMID:
27127107
24.

New pentasubstituted pyrrole hybrid atorvastatin-quinoline derivatives with antiplasmodial activity.

Carvalho RC, Martins WA, Silva TP, Kaiser CR, Bastos MM, Pinheiro LC, Krettli AU, Boechat N.

Bioorg Med Chem Lett. 2016 Apr 15;26(8):1881-4. doi: 10.1016/j.bmcl.2016.03.027. Epub 2016 Mar 9.

PMID:
26988303
25.

Efavirenz a nonnucleoside reverse transcriptase inhibitor of first-generation: Approaches based on its medicinal chemistry.

Bastos MM, Costa CCP, Bezerra TC, da Silva FC, Boechat N.

Eur J Med Chem. 2016 Jan 27;108:455-465. doi: 10.1016/j.ejmech.2015.11.025. Epub 2015 Nov 25. Review.

PMID:
26708112
26.

Preparation of robust polyamide microcapsules by interfacial polycondensation of p-phenylenediamine and sebacoyl chloride and plasticization with oleic acid.

Rosa N, Martins GV, Bastos MM, Gois JR, Coelho JF, Marques J, Tavares CJ, Magalhães FD.

J Microencapsul. 2015;32(4):349-57. doi: 10.3109/02652048.2015.1028494. Epub 2015 Jun 8.

PMID:
26052719
27.

Novel selective inhibitor of Leishmania (Leishmania) amazonensis arginase.

da Silva ER, Boechat N, Pinheiro LC, Bastos MM, Costa CC, Bartholomeu JC, da Costa TH.

Chem Biol Drug Des. 2015 Nov;86(5):969-78. doi: 10.1111/cbdd.12566. Epub 2015 May 14.

PMID:
25845502
28.

MicroRNA-21 expression and susceptibility to HPV-induced carcinogenesis - role of microenvironment in K14-HPV16 mice model.

Paiva I, Gil da Costa RM, Ribeiro J, Sousa H, Bastos MM, Faustino-Rocha A, Lopes C, Oliveira PA, Medeiros R.

Life Sci. 2015 May 1;128:8-14. doi: 10.1016/j.lfs.2015.02.020. Epub 2015 Mar 12. No abstract available.

PMID:
25771247
29.

Evaluation of genotoxic effects of new molecules with possible trypanocidal activity for Chagas disease treatment.

Mello FV, Carvalho AS, Bastos MM, Boechat N, Aiub CA, Felzenszwalb I.

ScientificWorldJournal. 2013 Nov 7;2013:287319. doi: 10.1155/2013/287319. eCollection 2013.

30.

Fluorinated compounds against Mycobacterium tuberculosis.

Boechat N, Bastos MM.

Curr Top Med Chem. 2013;13(22):2885-904. Review.

PMID:
24111908
31.

Endodontic treatment of mandibular molar with root dilaceration using Reciproc single-file system.

Meireles DA, Bastos MM, Marques AA, Garcia Lda F, Sponchiado EC Júnior.

Restor Dent Endod. 2013 Aug;38(3):167-71. doi: 10.5395/rde.2013.38.3.167. Epub 2013 Aug 23.

32.

Sesquiterpene lactones: adverse health effects and toxicity mechanisms.

Amorim MH, Gil da Costa RM, Lopes C, Bastos MM.

Crit Rev Toxicol. 2013 Aug;43(7):559-79. doi: 10.3109/10408444.2013.813905. Review.

PMID:
23875764
33.

Recovery of humic-like susbtances from low quality composts.

Silva ME, Lemos LT, Bastos MM, Nunes OC, Cunha-Queda AC.

Bioresour Technol. 2013 Jan;128:624-32. doi: 10.1016/j.biortech.2012.11.013. Epub 2012 Nov 12.

PMID:
23211490
34.

Ptaquiloside-induced early-stage urothelial lesions show increased cell proliferation and intact β-catenin and E-cadherin expression.

Gil da Costa RM, Oliveira PA, Bastos MM, Lopes CC, Lopes C.

Environ Toxicol. 2014 May;29(7):763-9. doi: 10.1002/tox.21803. Epub 2012 Aug 1.

PMID:
22859263
35.

New trifluoromethyl triazolopyrimidines as anti-Plasmodium falciparum agents.

Boechat N, Pinheiro LC, Silva TS, Aguiar AC, Carvalho AS, Bastos MM, Costa CC, Pinheiro S, Pinto AC, Mendonça JS, Dutra KD, Valverde AL, Santos-Filho OA, Ceravolo IP, Krettli AU.

Molecules. 2012 Jul 10;17(7):8285-302. doi: 10.3390/molecules17078285.

36.

Multiple genotoxic activities of ptaquiloside in human lymphocytes: aneugenesis, clastogenesis and induction of sister chromatid exchange.

Gil da Costa RM, Coelho P, Sousa R, Bastos MM, Porto B, Teixeira JP, Malheiro I, Lopes C.

Mutat Res. 2012 Aug 30;747(1):77-81. doi: 10.1016/j.mrgentox.2012.04.010. Epub 2012 Apr 28.

PMID:
22565221
37.

Bracken-associated human and animal health hazards: chemical, biological and pathological evidence.

Gil da Costa RM, Bastos MM, Oliveira PA, Lopes C.

J Hazard Mater. 2012 Feb 15;203-204:1-12. doi: 10.1016/j.jhazmat.2011.12.046. Epub 2011 Dec 24. Review.

PMID:
22226718
38.

[1-(3-Chloro-phen-yl)-1H-1,2,3-triazol-4-yl]methanol hemihydrate.

Boechat N, Ferreira Mde L, Bastos MM, Wardell JL, Wardell SM, Tiekink ER.

Acta Crystallogr Sect E Struct Rep Online. 2011 Nov;67(Pt 11):o2934-5. doi: 10.1107/S1600536811041560. Epub 2011 Oct 12.

39.

Ptaquiloside-induced, B-cell lymphoproliferative and early-stage urothelial lesions in mice.

Gil da Costa RM, Oliveira PA, Vilanova M, Bastos MM, Lopes CC, Lopes C.

Toxicon. 2011 Nov;58(6-7):543-9. doi: 10.1016/j.toxicon.2011.08.016. Epub 2011 Sep 1.

PMID:
21907228
40.

Novel 1,2,3-triazole derivatives for use against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain.

Boechat N, Ferreira VF, Ferreira SB, de Lourdes G Ferreira M, de C da Silva F, Bastos MM, Dos S Costa M, Lourenço MC, Pinto AC, Krettli AU, Aguiar AC, Teixeira BM, da Silva NV, Martins PR, Bezerra FA, Camilo AL, da Silva GP, Costa CC.

J Med Chem. 2011 Sep 8;54(17):5988-99. doi: 10.1021/jm2003624. Epub 2011 Aug 15.

PMID:
21776985
41.

Biofouling control using microparticles carrying a biocide.

Ferreira C, Rosmaninho R, Simoes M, Pereira MC, Bastos MM, Nunes OC, Coelho M, Melo LF.

Biofouling. 2010;26(2):205-12. doi: 10.1080/08927010903419630.

PMID:
19937490
42.

Eleven amino acid glucagon-like peptide-1 receptor agonists with antidiabetic activity.

Mapelli C, Natarajan SI, Meyer JP, Bastos MM, Bernatowicz MS, Lee VG, Pluscec J, Riexinger DJ, Sieber-McMaster ES, Constantine KL, Smith-Monroy CA, Golla R, Ma Z, Longhi DA, Shi D, Xin L, Taylor JR, Koplowitz B, Chi CL, Khanna A, Robinson GW, Seethala R, Antal-Zimanyi IA, Stoffel RH, Han S, Whaley JM, Huang CS, Krupinski J, Ewing WR.

J Med Chem. 2009 Dec 10;52(23):7788-99. doi: 10.1021/jm900752a.

PMID:
19702274
43.

New insights into a bacterial metabolic and detoxifying association responsible for the mineralization of the thiocarbamate herbicide molinate.

Barreiros L, Fernandes A, Ferreira AC, Pereira H, Bastos MM, Manaia CM, Nunes OC.

Microbiology. 2008 Apr;154(Pt 4):1038-46. doi: 10.1099/mic.0.2007/015297-0.

PMID:
18375797
44.

Managing suspected venous thromboembolism in a mixed primary and secondary care setting using standard clinical assessment and D-dimer in a noninvasive diagnostic strategy.

de Bastos MM, Bastos MR, Pessoa PC, Bogutchi T, Carneiro-Proietti AB, Rezende SM.

Blood Coagul Fibrinolysis. 2008 Jan;19(1):48-54. doi: 10.1097/MBC.0b013e3282f1855f.

PMID:
18180615
45.

Design, synthesis and pharmacological evaluation of HIV-1 reverse transcriptase inhibition of new indolin-2-ones.

Boechat N, Kover WB, Bongertz V, Bastos MM, Romeiro NC, Azevedo ML, Wollinger W.

Med Chem. 2007 Nov;3(6):533-42.

PMID:
18045202
46.

Lignans and Other Constituents of Centaurea sphaerocephala ssp. polyacantha.

Bastos MM, Kijjoa A, Cardoso JM, Gutiérrez AB, Herz W.

Planta Med. 1990 Aug;56(4):403-5.

PMID:
17221437

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