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Dealing with several flagella in the same cell.

Bertiaux E, Bastin P.

Cell Microbiol. 2020 Jan 16:e13162. doi: 10.1111/cmi.13162. [Epub ahead of print] Review.


[Molecular motors and microtubules: which type of relationship?]

Mallet A, Bastin P.

Med Sci (Paris). 2019 Apr;35(4):302-304. doi: 10.1051/medsci/2019062. Epub 2019 Apr 30. French. No abstract available.


Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly.

Wachter S, Jung J, Shafiq S, Basquin J, Fort C, Bastin P, Lorentzen E.

EMBO J. 2019 May 2;38(9). pii: e101251. doi: 10.15252/embj.2018101251. Epub 2019 Apr 2.


Indirubin Analogues Inhibit Trypanosoma brucei Glycogen Synthase Kinase 3 Short and T. brucei Growth.

Efstathiou A, Gaboriaud-Kolar N, Myrianthopoulos V, Vougogiannopoulou K, Subota I, Aicher S, Mikros E, Bastin P, Skaltsounis AL, Soteriadou K, Smirlis D.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e02065-18. doi: 10.1128/AAC.02065-18. Print 2019 Jun.


IFT25 is required for the construction of the trypanosome flagellum.

Huet D, Blisnick T, Perrot S, Bastin P.

J Cell Sci. 2019 Feb 22;132(5). pii: jcs228296. doi: 10.1242/jcs.228296.


Absence of genotoxic impact assessed by micronucleus frequency in circulating lymphocytes of workers exposed to cadmium.

Lison D, Van Maele-Fabry G, Vral A, Vermeulen S, Bastin P, Haufroid V, Baeyens A.

Toxicol Lett. 2019 Mar 15;303:72-77. doi: 10.1016/j.toxlet.2018.12.014. Epub 2018 Dec 31.


A Grow-and-Lock Model for the Control of Flagellum Length in Trypanosomes.

Bertiaux E, Morga B, Blisnick T, Rotureau B, Bastin P.

Curr Biol. 2018 Dec 3;28(23):3802-3814.e3. doi: 10.1016/j.cub.2018.10.031. Epub 2018 Nov 15.


Biallelic Mutations in LRRC56, Encoding a Protein Associated with Intraflagellar Transport, Cause Mucociliary Clearance and Laterality Defects.

Bonnefoy S, Watson CM, Kernohan KD, Lemos M, Hutchinson S, Poulter JA, Crinnion LA, Berry I, Simmonds J, Vasudevan P, O'Callaghan C, Hirst RA, Rutman A, Huang L, Hartley T, Grynspan D, Moya E, Li C, Carr IM, Bonthron DT, Leroux M; Care4Rare Canada Consortium, Boycott KM, Bastin P, Sheridan EG.

Am J Hum Genet. 2018 Nov 1;103(5):727-739. doi: 10.1016/j.ajhg.2018.10.003.


Bidirectional intraflagellar transport is restricted to two sets of microtubule doublets in the trypanosome flagellum.

Bertiaux E, Mallet A, Fort C, Blisnick T, Bonnefoy S, Jung J, Lemos M, Marco S, Vaughan S, Trépout S, Tinevez JY, Bastin P.

J Cell Biol. 2018 Dec 3;217(12):4284-4297. doi: 10.1083/jcb.201805030. Epub 2018 Oct 1.


Salivary cortisol testing: preanalytic and analytic aspects.

Bastin P, Maiter D, Gruson D.

Ann Biol Clin (Paris). 2018 Aug 1;76(4):393-405. doi: 10.1684/abc.2018.1355. Review.


Assessment of in vitro stability: a call for harmonization across studies.

Bastin P, Favresse J, Streel C, Maisin D, Fillée C, Gruson D.

Clin Chem Lab Med. 2018 Apr 25;56(5):e121-e124. doi: 10.1515/cclm-2017-1024. No abstract available.


STEM tomography analysis of the trypanosome transition zone.

Trépout S, Tassin AM, Marco S, Bastin P.

J Struct Biol. 2018 Apr;202(1):51-60. doi: 10.1016/j.jsb.2017.12.005. Epub 2017 Dec 14.


Flagellar incorporation of proteins follows at least two different routes in trypanosomes.

Vincensini L, Blisnick T, Bertiaux E, Hutchinson S, Georgikou C, Ooi CP, Bastin P.

Biol Cell. 2018 Feb;110(2):33-47. doi: 10.1111/boc.201700052. Epub 2017 Dec 11.


Preparation and Observation of Thick Biological Samples by Scanning Transmission Electron Tomography.

Trépout S, Bastin P, Marco S.

J Vis Exp. 2017 Mar 12;(121). doi: 10.3791/55215.


A two-phase approach for the identification of refugees with priority need for mental health care in Lebanon: a validation study.

Llosa AE, Van Ommeren M, Kolappa K, Ghantous Z, Souza R, Bastin P, Slavuckij A, Grais RF.

BMC Psychiatry. 2017 Jan 18;17(1):28. doi: 10.1186/s12888-016-1154-5.


Escalation of Commitment in Treatment Decisions Near the End of Life.

Knoops L, Bastin P.

JAMA Oncol. 2017 Sep 1;3(9):1174-1175. doi: 10.1001/jamaoncol.2016.5490. No abstract available.


Intraflagellar transport is required for the maintenance of the trypanosome flagellum composition but not its length.

Fort C, Bonnefoy S, Kohl L, Bastin P.

J Cell Sci. 2016 Aug 1;129(15):3026-41. doi: 10.1242/jcs.188227. Epub 2016 Jun 24.


Flagellar membranes are rich in raft-forming phospholipids.

Serricchio M, Schmid AW, Steinmann ME, Sigel E, Rauch M, Julkowska D, Bonnefoy S, Fort C, Bastin P, Bütikofer P.

Biol Open. 2015 Aug 14;4(9):1143-53. doi: 10.1242/bio.011957.


IFT81, encoding an IFT-B core protein, as a very rare cause of a ciliopathy phenotype.

Perrault I, Halbritter J, Porath JD, Gérard X, Braun DA, Gee HY, Fathy HM, Saunier S, Cormier-Daire V, Thomas S, Attié-Bitach T, Boddaert N, Taschner M, Schueler M, Lorentzen E, Lifton RP, Lawson JA, Garfa-Traore M, Otto EA, Bastin P, Caillaud C, Kaplan J, Rozet JM, Hildebrandt F.

J Med Genet. 2015 Oct;52(10):657-65. doi: 10.1136/jmedgenet-2014-102838. Epub 2015 Aug 14.


The Flagellar Arginine Kinase in Trypanosoma brucei Is Important for Infection in Tsetse Flies.

Ooi CP, Rotureau B, Gribaldo S, Georgikou C, Julkowska D, Blisnick T, Perrot S, Subota I, Bastin P.

PLoS One. 2015 Jul 28;10(7):e0133676. doi: 10.1371/journal.pone.0133676. eCollection 2015.


Scanning transmission electron microscopy through-focal tilt-series on biological specimens.

Trepout S, Messaoudi C, Perrot S, Bastin P, Marco S.

Micron. 2015 Oct;77:9-15. doi: 10.1016/j.micron.2015.05.015. Epub 2015 May 29.


The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies.

Benmerah A, Durand B, Giles RH, Harris T, Kohl L, Laclef C, Meilhac SM, Mitchison HM, Pedersen LB, Roepman R, Swoboda P, Ueffing M, Bastin P.

Cilia. 2015 Mar 31;4:5. doi: 10.1186/s13630-015-0014-0. eCollection 2015.


Imaging intraflagellar transport in trypanosomes.

Santi-Rocca J, Chenouard N, Fort C, Lagache T, Olivo-Marin JC, Bastin P.

Methods Cell Biol. 2015;127:487-508. doi: 10.1016/bs.mcb.2015.01.005. Epub 2015 Mar 7.


Social motility in African trypanosomes: fact or model?

Bastin P, Rotureau B.

Trends Parasitol. 2015 Feb;31(2):37-8. doi: 10.1016/ Epub 2015 Jan 8.


Generation of a nanobody targeting the paraflagellar rod protein of trypanosomes.

Obishakin E, Stijlemans B, Santi-Rocca J, Vandenberghe I, Devreese B, Muldermans S, Bastin P, Magez S.

PLoS One. 2014 Dec 31;9(12):e115893. doi: 10.1371/journal.pone.0115893. eCollection 2014.


[Elongation of the axoneme and dynamics of intraflagellar transport].

Fort C, Bastin P.

Med Sci (Paris). 2014 Nov;30(11):955-61. doi: 10.1051/medsci/20143011008. Epub 2014 Nov 10. Review. French.


The intraflagellar transport dynein complex of trypanosomes is made of a heterodimer of dynein heavy chains and of light and intermediate chains of distinct functions.

Blisnick T, Buisson J, Absalon S, Marie A, Cayet N, Bastin P.

Mol Biol Cell. 2014 Sep 1;25(17):2620-33. doi: 10.1091/mbc.E14-05-0961. Epub 2014 Jul 2.


The GTPase IFT27 is involved in both anterograde and retrograde intraflagellar transport.

Huet D, Blisnick T, Perrot S, Bastin P.

Elife. 2014 Apr 24;3:e02419. doi: 10.7554/eLife.02419.


The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage-specific phosphorylation status.

Yau WL, Pescher P, MacDonald A, Hem S, Zander D, Retzlaff S, Blisnick T, Rotureau B, Rosenqvist H, Wiese M, Bastin P, Clos J, Späth GF.

Mol Microbiol. 2014 Jul;93(1):80-97. doi: 10.1111/mmi.12639. Epub 2014 May 23.


Proteomic analysis of intact flagella of procyclic Trypanosoma brucei cells identifies novel flagellar proteins with unique sub-localization and dynamics.

Subota I, Julkowska D, Vincensini L, Reeg N, Buisson J, Blisnick T, Huet D, Perrot S, Santi-Rocca J, Duchateau M, Hourdel V, Rousselle JC, Cayet N, Namane A, Chamot-Rooke J, Bastin P.

Mol Cell Proteomics. 2014 Jul;13(7):1769-86. doi: 10.1074/mcp.M113.033357. Epub 2014 Apr 16.


Boarder control on the IFT train.

Fort C, Bastin P.

Elife. 2014 Mar 18;3:e02531. doi: 10.7554/eLife.02531.


More than meets the eye: understanding Trypanosoma brucei morphology in the tsetse.

Ooi CP, Bastin P.

Front Cell Infect Microbiol. 2013 Nov 13;3:71. doi: 10.3389/fcimb.2013.00071. eCollection 2013. Review.


Flagellar adhesion in Trypanosoma brucei relies on interactions between different skeletal structures in the flagellum and cell body.

Rotureau B, Blisnick T, Subota I, Julkowska D, Cayet N, Perrot S, Bastin P.

J Cell Sci. 2014 Jan 1;127(Pt 1):204-15. doi: 10.1242/jcs.136424. Epub 2013 Oct 25.


Forward motility is essential for trypanosome infection in the tsetse fly.

Rotureau B, Ooi CP, Huet D, Perrot S, Bastin P.

Cell Microbiol. 2014 Mar;16(3):425-33. doi: 10.1111/cmi.12230. Epub 2013 Nov 5.


Mental disorders, disability and treatment gap in a protracted refugee setting.

Llosa AE, Ghantous Z, Souza R, Forgione F, Bastin P, Jones A, Antierens A, Slavuckij A, Grais RF.

Br J Psychiatry. 2014 Mar;204(3):208-13. doi: 10.1192/bjp.bp.112.120535. Epub 2013 Sep 12.


Molecular basis of tubulin transport within the cilium by IFT74 and IFT81.

Bhogaraju S, Cajanek L, Fort C, Blisnick T, Weber K, Taschner M, Mizuno N, Lamla S, Bastin P, Nigg EA, Lorentzen E.

Science. 2013 Aug 30;341(6149):1009-12. doi: 10.1126/science.1240985.


Description and predictive factors of individual outcomes in a refugee camp based mental health intervention (Beirut, Lebanon).

Bastin P, Bastard M, Rossel L, Melgar P, Jones A, Antierens A.

PLoS One. 2013;8(1):e54107. doi: 10.1371/journal.pone.0054107. Epub 2013 Jan 17.


Apoptotic marker expression in the absence of cell death in staurosporine-treated Leishmania donovani.

Foucher AL, Rachidi N, Gharbi S, Blisnick T, Bastin P, Pemberton IK, Späth GF.

Antimicrob Agents Chemother. 2013 Mar;57(3):1252-61. doi: 10.1128/AAC.01983-12. Epub 2012 Dec 21.


Trypanosoma brucei FKBP12 differentially controls motility and cytokinesis in procyclic and bloodstream forms.

Brasseur A, Rotureau B, Vermeersch M, Blisnick T, Salmon D, Bastin P, Pays E, Vanhamme L, Pérez-Morga D.

Eukaryot Cell. 2013 Feb;12(2):168-81. doi: 10.1128/EC.00077-12. Epub 2012 Oct 26.


Intraflagellar transport proteins cycle between the flagellum and its base.

Buisson J, Chenouard N, Lagache T, Blisnick T, Olivo-Marin JC, Bastin P.

J Cell Sci. 2013 Jan 1;126(Pt 1):327-38. doi: 10.1242/jcs.117069. Epub 2012 Sep 19.


A new asymmetric division contributes to the continuous production of infective trypanosomes in the tsetse fly.

Rotureau B, Subota I, Buisson J, Bastin P.

Development. 2012 May;139(10):1842-50. doi: 10.1242/dev.072611. Epub 2012 Apr 4.


NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions.

DuBois KN, Alsford S, Holden JM, Buisson J, Swiderski M, Bart JM, Ratushny AV, Wan Y, Bastin P, Barry JD, Navarro M, Horn D, Aitchison JD, Rout MP, Field MC.

PLoS Biol. 2012;10(3):e1001287. doi: 10.1371/journal.pbio.1001287. Epub 2012 Mar 27.


ALBA proteins are stage regulated during trypanosome development in the tsetse fly and participate in differentiation.

Subota I, Rotureau B, Blisnick T, Ngwabyt S, Durand-Dubief M, Engstler M, Bastin P.

Mol Biol Cell. 2011 Nov;22(22):4205-19. doi: 10.1091/mbc.E11-06-0511. Epub 2011 Sep 30.


[The importance of model organisms to study cilia and flagella biology].

Vincensini L, Blisnick T, Bastin P.

Biol Aujourdhui. 2011;205(1):5-28. doi: 10.1051/jbio/2011005. Epub 2011 Apr 19. Review. French.


Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation.

Pescher P, Blisnick T, Bastin P, Späth GF.

Cell Microbiol. 2011 Jul;13(7):978-91. doi: 10.1111/j.1462-5822.2011.01593.x. Epub 2011 Apr 26.


The ciliary pocket: a once-forgotten membrane domain at the base of cilia.

Ghossoub R, Molla-Herman A, Bastin P, Benmerah A.

Biol Cell. 2011 Mar;103(3):131-44. doi: 10.1042/BC20100128. Review.


1001 model organisms to study cilia and flagella.

Vincensini L, Blisnick T, Bastin P.

Biol Cell. 2011 Mar;103(3):109-30. doi: 10.1042/BC20100104. Review.


Molecular bases of cytoskeleton plasticity during the Trypanosoma brucei parasite cycle.

Rotureau B, Subota I, Bastin P.

Cell Microbiol. 2011 May;13(5):705-16. doi: 10.1111/j.1462-5822.2010.01566.x. Epub 2011 Jan 18.


Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability.

Yau WL, Blisnick T, Taly JF, Helmer-Citterich M, Schiene-Fischer C, Leclercq O, Li J, Schmidt-Arras D, Morales MA, Notredame C, Romo D, Bastin P, Späth GF.

PLoS Negl Trop Dis. 2010 Jun 29;4(6):e729. doi: 10.1371/journal.pntd.0000729.

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