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Items: 26


Forward and Reverse Genetic Analysis of Chlamydia.

Kędzior M, Bastidas RJ.

Methods Mol Biol. 2019;2042:185-204. doi: 10.1007/978-1-4939-9694-0_13.


Ptr/CTL0175 Is Required for the Efficient Recovery of Chlamydia trachomatis From Stress Induced by Gamma-Interferon.

Panzetta ME, Luján AL, Bastidas RJ, Damiani MT, Valdivia RH, Saka HA.

Front Microbiol. 2019 Apr 10;10:756. doi: 10.3389/fmicb.2019.00756. eCollection 2019.


A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.

Pruneda JN, Bastidas RJ, Bertsoulaki E, Swatek KN, Santhanam B, Clague MJ, Valdivia RH, Urbé S, Komander D.

Nat Microbiol. 2018 Dec;3(12):1377-1384. doi: 10.1038/s41564-018-0271-y. Epub 2018 Nov 5.


The Expanding Molecular Genetics Tool Kit in Chlamydia.

Valdivia RH, Bastidas RJ.

J Bacteriol. 2018 Nov 26;200(24). pii: e00590-18. doi: 10.1128/JB.00590-18. Print 2018 Dec 15.


N-Acylated Derivatives of Sulfamethoxazole Block Chlamydia Fatty Acid Synthesis and Interact with FabF.

Mojica SA, Salin O, Bastidas RJ, Sunduru N, Hedenström M, Andersson CD, Núñez-Otero C, Engström P, Valdivia RH, Elofsson M, Gylfe Å.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00716-17. doi: 10.1128/AAC.00716-17. Print 2017 Oct.


The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs.

Sixt BS, Bastidas RJ, Finethy R, Baxter RM, Carpenter VK, Kroemer G, Coers J, Valdivia RH.

Cell Host Microbe. 2017 Jan 11;21(1):113-121. doi: 10.1016/j.chom.2016.12.002. Epub 2016 Dec 29.


Emancipating Chlamydia: Advances in the Genetic Manipulation of a Recalcitrant Intracellular Pathogen.

Bastidas RJ, Valdivia RH.

Microbiol Mol Biol Rev. 2016 Mar 30;80(2):411-27. doi: 10.1128/MMBR.00071-15. Print 2016 Jun. Review.


A Chlamydia trachomatis strain with a chemically generated amino acid substitution (P370L) in the cthtrA gene shows reduced elementary body production.

Marsh JW, Wee BA, Tyndall JD, Lott WB, Bastidas RJ, Caldwell HD, Valdivia RH, Kari L, Huston WM.

BMC Microbiol. 2015 Sep 30;15:194. doi: 10.1186/s12866-015-0533-2.


Integrating chemical mutagenesis and whole-genome sequencing as a platform for forward and reverse genetic analysis of Chlamydia.

Kokes M, Dunn JD, Granek JA, Nguyen BD, Barker JR, Valdivia RH, Bastidas RJ.

Cell Host Microbe. 2015 May 13;17(5):716-25. doi: 10.1016/j.chom.2015.03.014. Epub 2015 Apr 23.


A 2-pyridone-amide inhibitor targets the glucose metabolism pathway of Chlamydia trachomatis.

Engström P, Krishnan KS, Ngyuen BD, Chorell E, Normark J, Silver J, Bastidas RJ, Welch MD, Hultgren SJ, Wolf-Watz H, Valdivia RH, Almqvist F, Bergström S.

MBio. 2014 Dec 30;6(1):e02304-14. doi: 10.1128/mBio.02304-14.


Coxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication.

Larson CL, Beare PA, Voth DE, Howe D, Cockrell DC, Bastidas RJ, Valdivia RH, Heinzen RA.

Infect Immun. 2015 Feb;83(2):661-70. doi: 10.1128/IAI.02763-14. Epub 2014 Nov 24.


Antifungal drug resistance evoked via RNAi-dependent epimutations.

Calo S, Shertz-Wall C, Lee SC, Bastidas RJ, Nicolás FE, Granek JA, Mieczkowski P, Torres-Martínez S, Ruiz-Vázquez RM, Cardenas ME, Heitman J.

Nature. 2014 Sep 25;513(7519):555-8. doi: 10.1038/nature13575. Epub 2014 Jul 27.


Reassessing the role of the secreted protease CPAF in Chlamydia trachomatis infection through genetic approaches.

Snavely EA, Kokes M, Dunn JD, Saka HA, Nguyen BD, Bastidas RJ, McCafferty DG, Valdivia RH.

Pathog Dis. 2014 Aug;71(3):336-51. doi: 10.1111/2049-632X.12179. Epub 2014 May 16.


The Chlamydia trachomatis type III secretion chaperone Slc1 engages multiple early effectors, including TepP, a tyrosine-phosphorylated protein required for the recruitment of CrkI-II to nascent inclusions and innate immune signaling.

Chen YS, Bastidas RJ, Saka HA, Carpenter VK, Richards KL, Plano GV, Valdivia RH.

PLoS Pathog. 2014 Feb 20;10(2):e1003954. doi: 10.1371/journal.ppat.1003954. eCollection 2014 Feb. Erratum in: PLoS Pathog. 2014 Mar;10(3):e1004094.


Mutations in hemG mediate resistance to salicylidene acylhydrazides, demonstrating a novel link between protoporphyrinogen oxidase (HemG) and Chlamydia trachomatis infectivity.

Engström P, Nguyen BD, Normark J, Nilsson I, Bastidas RJ, Gylfe A, Elofsson M, Fields KA, Valdivia RH, Wolf-Watz H, Bergström S.

J Bacteriol. 2013 Sep;195(18):4221-30. doi: 10.1128/JB.00506-13. Epub 2013 Jul 12.


Chlamydial intracellular survival strategies.

Bastidas RJ, Elwell CA, Engel JN, Valdivia RH.

Cold Spring Harb Perspect Med. 2013 May 1;3(5):a010256. doi: 10.1101/cshperspect.a010256. Review.


Rapamycin exerts antifungal activity in vitro and in vivo against Mucor circinelloides via FKBP12-dependent inhibition of Tor.

Bastidas RJ, Shertz CA, Lee SC, Heitman J, Cardenas ME.

Eukaryot Cell. 2012 Mar;11(3):270-81. doi: 10.1128/EC.05284-11. Epub 2011 Dec 30.


Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom.

Shertz CA, Bastidas RJ, Li W, Heitman J, Cardenas ME.

BMC Genomics. 2010 Sep 23;11:510. doi: 10.1186/1471-2164-11-510.


The protein kinase Tor1 regulates adhesin gene expression in Candida albicans.

Bastidas RJ, Heitman J, Cardenas ME.

PLoS Pathog. 2009 Feb;5(2):e1000294. doi: 10.1371/journal.ppat.1000294. Epub 2009 Feb 6.


Trimorphic stepping stones pave the way to fungal virulence.

Bastidas RJ, Heitman J.

Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):351-2. doi: 10.1073/pnas.0811994106. Epub 2009 Jan 7. Review. No abstract available.


Signaling cascades as drug targets in model and pathogenic fungi.

Bastidas RJ, Reedy JL, Morales-Johansson H, Heitman J, Cardenas ME.

Curr Opin Investig Drugs. 2008 Aug;9(8):856-64. Review.


The virulence of human pathogenic fungi: notes from the South of France.

Reedy JL, Bastidas RJ, Heitman J.

Cell Host Microbe. 2007 Aug 16;2(2):77-83. Review.


A conserved family of enzymes that phosphorylate inositol hexakisphosphate.

Mulugu S, Bai W, Fridy PC, Bastidas RJ, Otto JC, Dollins DE, Haystead TA, Ribeiro AA, York JD.

Science. 2007 Apr 6;316(5821):106-9.


Generation of phytate-free seeds in Arabidopsis through disruption of inositol polyphosphate kinases.

Stevenson-Paulik J, Bastidas RJ, Chiou ST, Frye RA, York JD.

Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12612-7. Epub 2005 Aug 17.


[Mosquito fauna (Diptera:Culicidae) from Falcon State, Venezuela. I. New records and current checklist].

Navarro JC, Bastidas RJ, Zavala Y.

Acta Cient Venez. 1994;45(4):315-24. Spanish.


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