Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 39

1.

The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness.

Kari V, Raul SK, Henck JM, Kitz J, Kramer F, Kosinsky RL, Übelmesser N, Mansour WY, Eggert J, Spitzner M, Najafova Z, Bastians H, Grade M, Gaedcke J, Wegwitz F, Johnsen SA.

Clin Epigenetics. 2019 Jan 7;11(1):4. doi: 10.1186/s13148-018-0601-1.

2.

Correction: Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells.

Kramer D, Stark N, Schulz-Heddergott R, Erytch N, Edmunds S, Roßmann L, Bastians H, Concin N, Moll UM, Dobbelstein M.

Cell Death Differ. 2019 Mar;26(4):780. doi: 10.1038/s41418-018-0190-8.

3.

A Cell-Based Assay for Mitotic Spindle Orientation.

Glaubke E, Bastians H.

Methods Mol Biol. 2018;1787:67-75. doi: 10.1007/978-1-4939-7847-2_5.

PMID:
29736710
4.

Mitotic DNA Damage Response: At the Crossroads of Structural and Numerical Cancer Chromosome Instabilities.

Bakhoum SF, Kabeche L, Compton DA, Powell SN, Bastians H.

Trends Cancer. 2017 Mar;3(3):225-234. doi: 10.1016/j.trecan.2017.02.001. Epub 2017 Feb 28. Review.

5.

Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells.

Kramer D, Stark N, Schulz-Heddergott R, Erytch N, Edmunds S, Roßmann L, Bastians H, Concin N, Moll UM, Dobbelstein M.

Cell Death Differ. 2017 Feb;24(2):300-316. doi: 10.1038/cdd.2016.124. Epub 2016 Nov 11. Erratum in: Cell Death Differ. 2019 Mar;26(4):780.

6.

Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data.

Schrader A, Meyer K, Walther N, Stolz A, Feist M, Hand E, von Bonin F, Evers M, Kohler C, Shirneshan K, Vockerodt M, Klapper W, Szczepanowski M, Murray PG, Bastians H, Trümper L, Spang R, Kube D.

Oncotarget. 2016 Jul 26;7(30):47061-47081. doi: 10.18632/oncotarget.9219.

7.

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

Ertych N, Stolz A, Valerius O, Braus GH, Bastians H.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1817-22. doi: 10.1073/pnas.1525129113. Epub 2016 Feb 1.

8.

Causes of Chromosomal Instability.

Bastians H.

Recent Results Cancer Res. 2015;200:95-113. doi: 10.1007/978-3-319-20291-4_5. Review.

PMID:
26376874
9.

The putative oncogene CEP72 inhibits the mitotic function of BRCA1 and induces chromosomal instability.

Lüddecke S, Ertych N, Stenzinger A, Weichert W, Beissbarth T, Dyczkowski J, Gaedcke J, Valerius O, Braus GH, Kschischo M, Bastians H.

Oncogene. 2016 May 5;35(18):2398-406. doi: 10.1038/onc.2015.290. Epub 2015 Aug 24.

PMID:
26300001
10.

Fresh WNT into the regulation of mitosis.

Stolz A, Bastians H.

Cell Cycle. 2015;14(16):2566-70. doi: 10.1080/15384101.2015.1064569. Epub 2015 Jun 23.

11.

Microtubule plus tips: A dynamic route to chromosomal instability.

Stolz A, Ertych N, Bastians H.

Mol Cell Oncol. 2014 Oct 29;2(2):e960768. doi: 10.4161/23723548.2014.960768. eCollection 2015 Apr-Jun.

12.

Wnt-mediated protein stabilization ensures proper mitotic microtubule assembly and chromosome segregation.

Stolz A, Neufeld K, Ertych N, Bastians H.

EMBO Rep. 2015 Apr;16(4):490-9. doi: 10.15252/embr.201439410. Epub 2015 Feb 5.

13.

A phenotypic screen identifies microtubule plus end assembly regulators that can function in mitotic spindle orientation.

Stolz A, Ertych N, Bastians H.

Cell Cycle. 2015;14(6):827-37. doi: 10.1080/15384101.2014.1000693.

14.

Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells.

Ertych N, Stolz A, Stenzinger A, Weichert W, Kaulfuß S, Burfeind P, Aigner A, Wordeman L, Bastians H.

Nat Cell Biol. 2014 Aug;16(8):779-91. doi: 10.1038/ncb2994. Epub 2014 Jun 29.

15.

Therapeutic S and G2 checkpoint override causes centromere fragmentation in mitosis.

Stolz A, Bastians H.

Cell Cycle. 2013 Jun 15;12(12):1826-7. doi: 10.4161/cc.25175. Epub 2013 May 30. No abstract available.

16.

Therapeutic targeting of the mitotic spindle checkpoint through nanoparticle-mediated siRNA delivery inhibits tumor growth in vivo.

Kaestner P, Aigner A, Bastians H.

Cancer Lett. 2011 May 28;304(2):128-36. doi: 10.1016/j.canlet.2011.02.014. Epub 2011 Mar 5.

PMID:
21377782
17.

Loss of the tumour-suppressor genes CHK2 and BRCA1 results in chromosomal instability.

Stolz A, Ertych N, Bastians H.

Biochem Soc Trans. 2010 Dec;38(6):1704-8. doi: 10.1042/BST0381704.

PMID:
21118151
18.

Tumor suppressor CHK2: regulator of DNA damage response and mediator of chromosomal stability.

Stolz A, Ertych N, Bastians H.

Clin Cancer Res. 2011 Feb 1;17(3):401-5. doi: 10.1158/1078-0432.CCR-10-1215. Epub 2010 Nov 18.

19.

Mitotic drug targets.

Kaestner P, Bastians H.

J Cell Biochem. 2010 Oct 1;111(2):258-65. doi: 10.1002/jcb.22721.

PMID:
20518069
20.

Interaction of TACC3 and TSC2 at the nuclear envelope and mitotic structures.

Ertych N, Bastians H.

Cell Cycle. 2010 Apr 1;9(7):1233. Epub 2010 Apr 1. No abstract available.

PMID:
20404524
21.

Centromere localization of INCENP-Aurora B is sufficient to support spindle checkpoint function.

Becker M, Stolz A, Ertych N, Bastians H.

Cell Cycle. 2010 Apr 1;9(7):1360-72. Epub 2010 Apr 1.

PMID:
20372054
22.

The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells.

Stolz A, Ertych N, Kienitz A, Vogel C, Schneider V, Fritz B, Jacob R, Dittmar G, Weichert W, Petersen I, Bastians H.

Nat Cell Biol. 2010 May;12(5):492-9. doi: 10.1038/ncb2051. Epub 2010 Apr 4.

PMID:
20364141
23.

A novel role for Chk2 after DNA damage in mitosis?

Stolz A, Bastians H.

Cell Cycle. 2010 Jan 1;9(1):25-6. Epub 2010 Jan 1. No abstract available.

PMID:
20016261
24.

Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells.

Kaestner P, Stolz A, Bastians H.

Mol Cancer Ther. 2009 Jul;8(7):2046-56. doi: 10.1158/1535-7163.MCT-09-0323. Epub 2009 Jul 7.

25.

Pharmacologic abrogation of the mitotic spindle checkpoint by an indolocarbazole discovered by cellular screening efficiently kills cancer cells.

Stolz A, Vogel C, Schneider V, Ertych N, Kienitz A, Yu H, Bastians H.

Cancer Res. 2009 May 1;69(9):3874-83. doi: 10.1158/0008-5472.CAN-08-3597. Epub 2009 Apr 14.

26.

Mitotic drug targets and the development of novel anti-mitotic anticancer drugs.

Schmidt M, Bastians H.

Drug Resist Updat. 2007 Aug-Oct;10(4-5):162-81. Epub 2007 Jul 31. Review.

PMID:
17669681
27.

Mechanisms of mitotic cell death induced by chemotherapy-mediated G2 checkpoint abrogation.

Vogel C, Hager C, Bastians H.

Cancer Res. 2007 Jan 1;67(1):339-45.

28.

Partial downregulation of MAD1 causes spindle checkpoint inactivation and aneuploidy, but does not confer resistance towards taxol.

Kienitz A, Vogel C, Morales I, Müller R, Bastians H.

Oncogene. 2005 Jun 16;24(26):4301-10.

PMID:
15782113
29.

The mitotic spindle checkpoint is a critical determinant for topoisomerase-based chemotherapy.

Vogel C, Kienitz A, Müller R, Bastians H.

J Biol Chem. 2005 Feb 11;280(6):4025-8. Epub 2004 Dec 16.

30.

Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor.

Windgassen M, Sturm D, Cajigas IJ, González CI, Seedorf M, Bastians H, Krebber H.

Mol Cell Biol. 2004 Dec;24(23):10479-91.

31.

Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy.

Vogel C, Kienitz A, Hofmann I, Müller R, Bastians H.

Oncogene. 2004 Sep 9;23(41):6845-53.

PMID:
15286707
32.

Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes.

Topper LM, Bastians H, Ruderman JV, Gorbsky GJ.

J Cell Biol. 2001 Aug 20;154(4):707-17. Erratum in: J Cell Biol 2002 Jul 22;158(2):371.

33.

Cell cycle-regulated proteolysis of mitotic target proteins.

Bastians H, Topper LM, Gorbsky GL, Ruderman JV.

Mol Biol Cell. 1999 Nov;10(11):3927-41.

34.

The cyclin-dependent kinase inhibitor p27(Kip1) induces N-terminal proteolytic cleavage of cyclin A.

Bastians H, Townsley FM, Ruderman JV.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15374-81.

35.

EWS/FLI1 up regulates mE2-C, a cyclin-selective ubiquitin conjugating enzyme involved in cyclin B destruction.

Arvand A, Bastians H, Welford SM, Thompson AD, Ruderman JV, Denny CT.

Oncogene. 1998 Oct 22;17(16):2039-45.

36.

Localization of the gene encoding the Ran-binding protein RanBP2 to human chromosome 2q11-q13 by fluorescence in situ hybridization.

Krebber H, Bastians H, Hoheisel J, Lichter P, Ponstingl H, Joos S.

Genomics. 1997 Jul 15;43(2):247-8. No abstract available.

PMID:
9244446
37.

Assignment of the human serine/threonine protein phosphatase 4 gene (PPP4C) to chromosome 16p11-p12 by fluorescence in situ hybridization.

Bastians H, Krebber H, Hoheisel J, Ohl S, Lichter P, Ponstingl H, Joos S.

Genomics. 1997 May 15;42(1):181-2. No abstract available.

PMID:
9177794
38.

Localization of the novel serine/threonine protein phosphatase 6 gene (PPP6C) to human chromosome Xq22.3.

Bastians H, Krebber H, Vetrie D, Hoheisel J, Lichter P, Ponstingl H, Joos S.

Genomics. 1997 Apr 15;41(2):296-7. No abstract available.

PMID:
9143513

Supplemental Content

Loading ...
Support Center