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Items: 1 to 50 of 59

1.

Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma.

Meyer SN, Scuoppo C, Vlasevska S, Bal E, Holmes AB, Holloman M, Garcia-Ibanez L, Nataraj S, Duval R, Vantrimpont T, Basso K, Brooks N, Dalla-Favera R, Pasqualucci L.

Immunity. 2019 Sep 17;51(3):535-547.e9. doi: 10.1016/j.immuni.2019.08.006. Epub 2019 Sep 10.

PMID:
31519498
2.

Repurposing dasatinib for diffuse large B cell lymphoma.

Scuoppo C, Wang J, Persaud M, Mittan SK, Basso K, Pasqualucci L, Rabadan R, Inghirami G, Grandori C, Bosch F, Dalla-Favera R.

Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16981-16986. doi: 10.1073/pnas.1905239116. Epub 2019 Aug 5.

PMID:
31383760
3.

The Proteome of Pancreatic Cancer-Derived Exosomes Reveals Signatures Rich in Key Signaling Pathways.

Han S, Huo Z, Nguyen K, Zhu F, Underwood PW, Basso KBG, George TJ, Hughes SJ.

Proteomics. 2019 Jul;19(13):e1800394. doi: 10.1002/pmic.201800394. Epub 2019 Jun 11.

PMID:
31070281
4.

MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis.

Brescia P, Schneider C, Holmes AB, Shen Q, Hussein S, Pasqualucci L, Basso K, Dalla-Favera R.

Cancer Cell. 2018 Sep 10;34(3):453-465.e9. doi: 10.1016/j.ccell.2018.08.006.

5.

Singling out the out-of-tune in lymphoma.

Basso K.

Nat Immunol. 2018 Sep;19(9):903-905. doi: 10.1038/s41590-018-0189-9. No abstract available.

PMID:
30104632
6.

Clinical impact of miR-223 expression in pediatric T-Cell lymphoblastic lymphoma.

Pomari E, Lovisa F, Carraro E, Primerano S, D'Amore ESG, Bonvini P, Nigro LL, Vito R, Vinti L, Farruggia P, Pillon M, Basso G, Basso K, Mussolin L.

Oncotarget. 2017 Nov 11;8(64):107886-107898. doi: 10.18632/oncotarget.22386. eCollection 2017 Dec 8.

7.

The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma.

Zhang J, Vlasevska S, Wells VA, Nataraj S, Holmes AB, Duval R, Meyer SN, Mo T, Basso K, Brindle PK, Hussein S, Dalla-Favera R, Pasqualucci L.

Cancer Discov. 2017 Mar;7(3):322-337. doi: 10.1158/2159-8290.CD-16-1417. Epub 2017 Jan 9.

8.

NPM-ALK expression levels identify two distinct subtypes of paediatric anaplastic large cell lymphoma.

Pomari E, Basso G, Bresolin S, Pillon M, Carraro E, d'Amore ES, Viola G, Frasson C, Basso K, Bonvini P, Mussolin L.

Leukemia. 2017 Feb;31(2):498-501. doi: 10.1038/leu.2016.292. Epub 2016 Oct 24. No abstract available.

PMID:
27773932
9.

FBXO11 inactivation leads to abnormal germinal-center formation and lymphoproliferative disease.

Schneider C, Kon N, Amadori L, Shen Q, Schwartz FH, Tischler B, Bossennec M, Dominguez-Sola D, Bhagat G, Gu W, Basso K, Dalla-Favera R.

Blood. 2016 Aug 4;128(5):660-6. doi: 10.1182/blood-2015-11-684357. Epub 2016 May 10.

PMID:
27166359
10.

[Satisfaction with life, dental experience and self-perception of oral health among the elderly].

Rigo L, Basso K, Pauli J, Cericato GO, Paranhos LR, Garbin RR.

Cien Saude Colet. 2015 Dec;20(12):3681-8. doi: 10.1590/1413-812320152012.18432014. Portuguese.

11.

The FOXO1 Transcription Factor Instructs the Germinal Center Dark Zone Program.

Dominguez-Sola D, Kung J, Holmes AB, Wells VA, Mo T, Basso K, Dalla-Favera R.

Immunity. 2015 Dec 15;43(6):1064-74. doi: 10.1016/j.immuni.2015.10.015. Epub 2015 Nov 24.

12.

Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.

Zhang J, Dominguez-Sola D, Hussein S, Lee JE, Holmes AB, Bansal M, Vlasevska S, Mo T, Tang H, Basso K, Ge K, Dalla-Favera R, Pasqualucci L.

Nat Med. 2015 Oct;21(10):1190-8. doi: 10.1038/nm.3940. Epub 2015 Sep 14.

13.

Germinal centres and B cell lymphomagenesis.

Basso K, Dalla-Favera R.

Nat Rev Immunol. 2015 Mar;15(3):172-84. doi: 10.1038/nri3814. Review.

PMID:
25712152
14.

MicroRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas.

Schneider C, Setty M, Holmes AB, Maute RL, Leslie CS, Mussolin L, Rosolen A, Dalla-Favera R, Basso K.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8185-90. doi: 10.1073/pnas.1322466111. Epub 2014 May 19.

15.

An aberrant microRNA signature in childhood T-cell lymphoblastic lymphoma affecting CDKN1B expression, NOTCH1 and growth factor signaling pathways.

Mussolin L, Holmes AB, Romualdi C, Sales G, D'Amore ES, Ghisi M, Pillon M, Rosolen A, Basso K.

Leukemia. 2014 Sep;28(9):1909-12. doi: 10.1038/leu.2014.134. Epub 2014 Apr 14. No abstract available.

PMID:
24727675
16.

Deoxynivanelol and fumonisin, alone or in combination, induce changes on intestinal junction complexes and in E-cadherin expression.

Basso K, Gomes F, Bracarense AP.

Toxins (Basel). 2013 Nov 28;5(12):2341-52. doi: 10.3390/toxins5122341.

17.

RNAs with multiple personalities.

Maute RL, Dalla-Favera R, Basso K.

Wiley Interdiscip Rev RNA. 2014 Jan-Feb;5(1):1-13. doi: 10.1002/wrna.1193. Epub 2013 Aug 20. Review.

PMID:
24039180
18.

MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma.

Ying CY, Dominguez-Sola D, Fabi M, Lorenz IC, Hussein S, Bansal M, Califano A, Pasqualucci L, Basso K, Dalla-Favera R.

Nat Immunol. 2013 Oct;14(10):1084-92. doi: 10.1038/ni.2688. Epub 2013 Aug 25.

19.

tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma.

Maute RL, Schneider C, Sumazin P, Holmes A, Califano A, Basso K, Dalla-Favera R.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1404-9. doi: 10.1073/pnas.1206761110. Epub 2013 Jan 7.

20.

Gene expression profile analysis of lymphomas.

Basso K, Klein U.

Methods Mol Biol. 2013;971:213-26. doi: 10.1007/978-1-62703-269-8_12.

PMID:
23296966
21.

BCL6 positively regulates AID and germinal center gene expression via repression of miR-155.

Basso K, Schneider C, Shen Q, Holmes AB, Setty M, Leslie C, Dalla-Favera R.

J Exp Med. 2012 Dec 17;209(13):2455-65. doi: 10.1084/jem.20121387. Epub 2012 Nov 19.

22.

A microRNA signature specific for hairy cell leukemia and associated with modulation of the MAPK-JNK pathways.

Kitagawa Y, Brahmachary M, Tiacci E, Dalla-Favera R, Falini B, Basso K.

Leukemia. 2012 Dec;26(12):2564-7. doi: 10.1038/leu.2012.149. Epub 2012 Jun 4. No abstract available.

PMID:
22660186
23.

Roles of BCL6 in normal and transformed germinal center B cells.

Basso K, Dalla-Favera R.

Immunol Rev. 2012 May;247(1):172-83. doi: 10.1111/j.1600-065X.2012.01112.x. Review.

PMID:
22500840
24.

T-cell lymphoblastic lymphoma shows differences and similarities with T-cell acute lymphoblastic leukemia by genomic and gene expression analyses.

Basso K, Mussolin L, Lettieri A, Brahmachary M, Lim WK, Califano A, Basso G, Biondi A, Cazzaniga G, Rosolen A.

Genes Chromosomes Cancer. 2011 Dec;50(12):1063-75. doi: 10.1002/gcc.20924. Epub 2011 Aug 30.

PMID:
21987448
25.

Genomic analysis of non-splenic marginal zone lymphomas (MZL) indicates similarities between nodal and extranodal MZL and supports their derivation from memory B-cells.

Novak U, Basso K, Pasqualucci L, Dalla-Favera R, Bhagat G.

Br J Haematol. 2011 Nov;155(3):362-5. doi: 10.1111/j.1365-2141.2011.08841.x. Epub 2011 Aug 25.

PMID:
21883140
26.

Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150.

Ghisi M, Corradin A, Basso K, Frasson C, Serafin V, Mukherjee S, Mussolin L, Ruggero K, Bonanno L, Guffanti A, De Bellis G, Gerosa G, Stellin G, D'Agostino DM, Basso G, Bronte V, Indraccolo S, Amadori A, Zanovello P.

Blood. 2011 Jun 30;117(26):7053-62. doi: 10.1182/blood-2010-12-326629. Epub 2011 May 6.

PMID:
21551231
27.

A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers.

Lefebvre C, Rajbhandari P, Alvarez MJ, Bandaru P, Lim WK, Sato M, Wang K, Sumazin P, Kustagi M, Bisikirska BC, Basso K, Beltrao P, Krogan N, Gautier J, Dalla-Favera R, Califano A.

Mol Syst Biol. 2010 Jun 8;6:377. doi: 10.1038/msb.2010.31.

28.

BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis.

Basso K, Dalla-Favera R.

Adv Immunol. 2010;105:193-210. doi: 10.1016/S0065-2776(10)05007-8. Review.

PMID:
20510734
29.

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.

Basso K, Saito M, Sumazin P, Margolin AA, Wang K, Lim WK, Kitagawa Y, Schneider C, Alvarez MJ, Califano A, Dalla-Favera R.

Blood. 2010 Feb 4;115(5):975-84. doi: 10.1182/blood-2009-06-227017. Epub 2009 Dec 3.

30.

Genome-wide identification of post-translational modulators of transcription factor activity in human B cells.

Wang K, Saito M, Bisikirska BC, Alvarez MJ, Lim WK, Rajbhandari P, Shen Q, Nemenman I, Basso K, Margolin AA, Klein U, Dalla-Favera R, Califano A.

Nat Biotechnol. 2009 Sep;27(9):829-39. doi: 10.1038/nbt.1563. Epub 2009 Sep 9.

31.

BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma.

Saito M, Novak U, Piovan E, Basso K, Sumazin P, Schneider C, Crespo M, Shen Q, Bhagat G, Califano A, Chadburn A, Pasqualucci L, Dalla-Favera R.

Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11294-9. doi: 10.1073/pnas.0903854106. Epub 2009 Jun 23.

32.

Identification of the human mature B cell miRNome.

Basso K, Sumazin P, Morozov P, Schneider C, Maute RL, Kitagawa Y, Mandelbaum J, Haddad J Jr, Chen CZ, Califano A, Dalla-Favera R.

Immunity. 2009 May;30(5):744-52. doi: 10.1016/j.immuni.2009.03.017. Epub 2009 May 14.

33.

Dissecting the interface between signaling and transcriptional regulation in human B cells.

Wang K, Alvarez MJ, Bisikirska BC, Linding R, Basso K, Dalla Favera R, Califano A.

Pac Symp Biocomput. 2009:264-75.

34.

Toward a systems biology approach to investigate cellular networks in normal and malignant B cells.

Basso K.

Leukemia. 2009 Jul;23(7):1219-25. doi: 10.1038/leu.2009.4. Epub 2009 Feb 5. Review.

PMID:
19194469
35.

Genetic and phenotypic analysis of B-cell post-transplant lymphoproliferative disorders provides insights into disease biology.

Vakiani E, Basso K, Klein U, Mansukhani MM, Narayan G, Smith PM, Murty VV, Dalla-Favera R, Pasqualucci L, Bhagat G.

Hematol Oncol. 2008 Dec;26(4):199-211. doi: 10.1002/hon.859.

PMID:
18457340
36.

The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression.

Shakya R, Szabolcs M, McCarthy E, Ospina E, Basso K, Nandula S, Murty V, Baer R, Ludwig T.

Proc Natl Acad Sci U S A. 2008 May 13;105(19):7040-5. doi: 10.1073/pnas.0711032105. Epub 2008 Apr 28.

37.

A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas.

Mani KM, Lefebvre C, Wang K, Lim WK, Basso K, Dalla-Favera R, Califano A.

Mol Syst Biol. 2008;4:169. doi: 10.1038/msb.2008.2. Epub 2008 Feb 12.

38.

Gene expression profile analysis of tumors.

Basso K, Dalla-Favera R.

Methods Mol Biol. 2007;383:67-79. doi: 10.1007/978-1-59745-335-6_5.

PMID:
18217679
39.

Gene expression profiling suggests primary central nervous system lymphomas to be derived from a late germinal center B cell.

Montesinos-Rongen M, Brunn A, Bentink S, Basso K, Lim WK, Klapper W, Schaller C, Reifenberger G, Rubenstein J, Wiestler OD, Spang R, Dalla-Favera R, Siebert R, Deckert M.

Leukemia. 2008 Feb;22(2):400-5. Epub 2007 Nov 8.

40.

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.

Saito M, Gao J, Basso K, Kitagawa Y, Smith PM, Bhagat G, Pernis A, Pasqualucci L, Dalla-Favera R.

Cancer Cell. 2007 Sep;12(3):280-92. Erratum in: Cancer Cell. 2007 Oct;12(4):403.

41.

Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets.

Piccaluga PP, Agostinelli C, Califano A, Rossi M, Basso K, Zupo S, Went P, Klein U, Zinzani PL, Baccarani M, Dalla Favera R, Pileri SA.

J Clin Invest. 2007 Mar;117(3):823-34. Epub 2007 Feb 15.

42.

Gene dosage alterations revealed by cDNA microarray analysis in cervical cancer: identification of candidate amplified and overexpressed genes.

Narayan G, Bourdon V, Chaganti S, Arias-Pulido H, Nandula SV, Rao PH, Gissmann L, Dürst M, Schneider A, Pothuri B, Mansukhani M, Basso K, Chaganti RS, Murty VV.

Genes Chromosomes Cancer. 2007 Apr;46(4):373-84.

PMID:
17243165
43.

Identification of rare Epstein-Barr virus infected memory B cells and plasma cells in non-monomorphic post-transplant lymphoproliferative disorders and the signature of viral signaling.

Shaknovich R, Basso K, Bhagat G, Mansukhani M, Hatzivassiliou G, Murty VV, Buettner M, Niedobitek G, Alobeid B, Cattoretti G.

Haematologica. 2006 Oct;91(10):1313-20.

44.

ARACNE: an algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context.

Margolin AA, Nemenman I, Basso K, Wiggins C, Stolovitzky G, Dalla Favera R, Califano A.

BMC Bioinformatics. 2006 Mar 20;7 Suppl 1:S7.

45.

BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells.

Phan RT, Saito M, Basso K, Niu H, Dalla-Favera R.

Nat Immunol. 2005 Oct;6(10):1054-60. Epub 2005 Sep 4.

PMID:
16142238
46.

Reverse engineering of regulatory networks in human B cells.

Basso K, Margolin AA, Stolovitzky G, Klein U, Dalla-Favera R, Califano A.

Nat Genet. 2005 Apr;37(4):382-90. Epub 2005 Mar 20.

PMID:
15778709
47.

Tracking CD40 signaling during germinal center development.

Basso K, Klein U, Niu H, Stolovitzky GA, Tu Y, Califano A, Cattoretti G, Dalla-Favera R.

Blood. 2004 Dec 15;104(13):4088-96. Epub 2004 Aug 26.

PMID:
15331443
48.

Distinct types of primary cutaneous large B-cell lymphoma identified by gene expression profiling.

Hoefnagel JJ, Dijkman R, Basso K, Jansen PM, Hallermann C, Willemze R, Tensen CP, Vermeer MH.

Blood. 2005 May 1;105(9):3671-8. Epub 2004 Aug 12.

PMID:
15308563
49.

Molecular pathogenesis of non-Hodgkin's lymphoma: the role of Bcl-6.

Pasqualucci L, Bereshchenko O, Niu H, Klein U, Basso K, Guglielmino R, Cattoretti G, Dalla-Favera R.

Leuk Lymphoma. 2003;44 Suppl 3:S5-12. Review. Erratum in: Leuk Lymphoma. 2013 May;54(5):1121. Bereschenko, Oxana [corrected to Bereshchenko, Oxana].

PMID:
15202519
50.

Simple diagnostic assay for hairy cell leukaemia by immunocytochemical detection of annexin A1 (ANXA1).

Falini B, Tiacci E, Liso A, Basso K, Sabattini E, Pacini R, Foa R, Pulsoni A, Dalla Favera R, Pileri S.

Lancet. 2004 Jun 5;363(9424):1869-70. Erratum in: Lancet. 2004 Jun 26;363(9427):2194.

PMID:
15183626

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