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Items: 1 to 50 of 178

1.

CRISPR Correction of Duchenne Muscular Dystrophy.

Min YL, Bassel-Duby R, Olson EN.

Annu Rev Med. 2018 Oct 31. doi: 10.1146/annurev-med-081117-010451. [Epub ahead of print]

PMID:
30379597
2.

The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.

Makarewich CA, Munir AZ, Schiattarella GG, Bezprozvannaya S, Raguimova ON, Cho EE, Vidal AH, Robia SL, Bassel-Duby R, Olson EN.

Elife. 2018 Oct 9;7. pii: e38319. doi: 10.7554/eLife.38319.

3.

Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy.

Amoasii L, Hildyard JCW, Li H, Sanchez-Ortiz E, Mireault A, Caballero D, Harron R, Stathopoulou TR, Massey C, Shelton JM, Bassel-Duby R, Piercy RJ, Olson EN.

Science. 2018 Oct 5;362(6410):86-91. doi: 10.1126/science.aau1549. Epub 2018 Aug 30.

4.

Identification of a multipotent Twist2-expressing cell population in the adult heart.

Min YL, Jaichander P, Sanchez-Ortiz E, Bezprozvannaya S, Malladi VS, Cui M, Wang Z, Bassel-Duby R, Olson EN, Liu N.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8430-E8439. doi: 10.1073/pnas.1800526115. Epub 2018 Aug 20.

PMID:
30127033
5.

MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation.

Makarewich CA, Baskin KK, Munir AZ, Bezprozvannaya S, Sharma G, Khemtong C, Shah AM, McAnally JR, Malloy CR, Szweda LI, Bassel-Duby R, Olson EN.

Cell Rep. 2018 Jun 26;23(13):3701-3709. doi: 10.1016/j.celrep.2018.05.058.

6.

Therapeutic approaches for cardiac regeneration and repair.

Hashimoto H, Olson EN, Bassel-Duby R.

Nat Rev Cardiol. 2018 Oct;15(10):585-600. doi: 10.1038/s41569-018-0036-6. Review.

7.

Myoediting: Toward Prevention of Muscular Dystrophy by Therapeutic Genome Editing.

Zhang Y, Long C, Bassel-Duby R, Olson EN.

Physiol Rev. 2018 Jul 1;98(3):1205-1240. doi: 10.1152/physrev.00046.2017. Review.

PMID:
29717930
8.

Cullin-3-RING ubiquitin ligase activity is required for striated muscle function in mice.

Papizan JB, Vidal AH, Bezprozvannaya S, Bassel-Duby R, Olson EN.

J Biol Chem. 2018 Jun 8;293(23):8802-8811. doi: 10.1074/jbc.RA118.002104. Epub 2018 Apr 13.

PMID:
29653945
9.

Fusogenic micropeptide Myomixer is essential for satellite cell fusion and muscle regeneration.

Bi P, McAnally JR, Shelton JM, Sánchez-Ortiz E, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3864-3869. doi: 10.1073/pnas.1800052115. Epub 2018 Mar 26.

10.

Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing.

Long C, Li H, Tiburcy M, Rodriguez-Caycedo C, Kyrychenko V, Zhou H, Zhang Y, Min YL, Shelton JM, Mammen PPA, Liaw NY, Zimmermann WH, Bassel-Duby R, Schneider JW, Olson EN.

Sci Adv. 2018 Jan 31;4(1):eaap9004. doi: 10.1126/sciadv.aap9004. eCollection 2018 Jan.

11.

Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy.

Amoasii L, Long C, Li H, Mireault AA, Shelton JM, Sanchez-Ortiz E, McAnally JR, Bhattacharyya S, Schmidt F, Grimm D, Hauschka SD, Bassel-Duby R, Olson EN.

Sci Transl Med. 2017 Nov 29;9(418). pii: eaan8081. doi: 10.1126/scitranslmed.aan8081. Erratum in: Sci Transl Med. 2018 Jan 24;10 (425):.

12.

Requirement of the fusogenic micropeptide myomixer for muscle formation in zebrafish.

Shi J, Bi P, Pei J, Li H, Grishin NV, Bassel-Duby R, Chen EH, Olson EN.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):11950-11955. doi: 10.1073/pnas.1715229114. Epub 2017 Oct 23.

13.

ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression.

Zhou H, Morales MG, Hashimoto H, Dickson ME, Song K, Ye W, Kim MS, Niederstrasser H, Wang Z, Chen B, Posner BA, Bassel-Duby R, Olson EN.

Genes Dev. 2017 Sep 1;31(17):1770-1783. doi: 10.1101/gad.305482.117.

14.

Functional correction of dystrophin actin binding domain mutations by genome editing.

Kyrychenko V, Kyrychenko S, Tiburcy M, Shelton JM, Long C, Schneider JW, Zimmermann WH, Bassel-Duby R, Olson EN.

JCI Insight. 2017 Sep 21;2(18). pii: 95918. doi: 10.1172/jci.insight.95918. [Epub ahead of print]

15.

Deficiency in Kelch protein Klhl31 causes congenital myopathy in mice.

Papizan JB, Garry GA, Brezprozvannaya S, McAnally JR, Bassel-Duby R, Liu N, Olson EN.

J Clin Invest. 2017 Oct 2;127(10):3730-3740. doi: 10.1172/JCI93445. Epub 2017 Sep 5.

16.

KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination.

Ramirez-Martinez A, Cenik BK, Bezprozvannaya S, Chen B, Bassel-Duby R, Liu N, Olson EN.

Elife. 2017 Aug 9;6. pii: e26439. doi: 10.7554/eLife.26439.

17.

MED12 regulates a transcriptional network of calcium-handling genes in the heart.

Baskin KK, Makarewich CA, DeLeon SM, Ye W, Chen B, Beetz N, Schrewe H, Bassel-Duby R, Olson EN.

JCI Insight. 2017 Jul 20;2(14). pii: 91920. doi: 10.1172/jci.insight.91920. [Epub ahead of print]

18.

CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice.

Zhang Y, Long C, Li H, McAnally JR, Baskin KK, Shelton JM, Bassel-Duby R, Olson EN.

Sci Adv. 2017 Apr 12;3(4):e1602814. doi: 10.1126/sciadv.1602814. eCollection 2017 Apr.

19.

Control of Muscle Metabolism by the Mediator Complex.

Amoasii L, Olson EN, Bassel-Duby R.

Cold Spring Harb Perspect Med. 2018 Feb 1;8(2). pii: a029843. doi: 10.1101/cshperspect.a029843. Review.

20.

Control of muscle formation by the fusogenic micropeptide myomixer.

Bi P, Ramirez-Martinez A, Li H, Cannavino J, McAnally JR, Shelton JM, Sánchez-Ortiz E, Bassel-Duby R, Olson EN.

Science. 2017 Apr 21;356(6335):323-327. doi: 10.1126/science.aam9361. Epub 2017 Apr 6.

21.

Notch Inhibition Enhances Cardiac Reprogramming by Increasing MEF2C Transcriptional Activity.

Abad M, Hashimoto H, Zhou H, Morales MG, Chen B, Bassel-Duby R, Olson EN.

Stem Cell Reports. 2017 Mar 14;8(3):548-560. doi: 10.1016/j.stemcr.2017.01.025. Epub 2017 Mar 2.

22.

A Twist2-dependent progenitor cell contributes to adult skeletal muscle.

Liu N, Garry GA, Li S, Bezprozvannaya S, Sanchez-Ortiz E, Chen B, Shelton JM, Jaichander P, Bassel-Duby R, Olson EN.

Nat Cell Biol. 2017 Mar;19(3):202-213. doi: 10.1038/ncb3477. Epub 2017 Feb 20.

23.

Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist.

Moon J, Zhou H, Zhang LS, Tan W, Liu Y, Zhang S, Morlock LK, Bao X, Palecek SP, Feng JQ, Williams NS, Amatruda JF, Olson EN, Bassel-Duby R, Lum L.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1649-1654. doi: 10.1073/pnas.1621346114. Epub 2017 Jan 31.

24.

Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides.

Anderson DM, Makarewich CA, Anderson KM, Shelton JM, Bezprozvannaya S, Bassel-Duby R, Olson EN.

Sci Signal. 2016 Dec 6;9(457):ra119.

25.

Transcription of the non-coding RNA upperhand controls Hand2 expression and heart development.

Anderson KM, Anderson DM, McAnally JR, Shelton JM, Bassel-Duby R, Olson EN.

Nature. 2016 Nov 17;539(7629):433-436. doi: 10.1038/nature20128. Epub 2016 Oct 26.

26.

Genome Editing of Monogenic Neuromuscular Diseases: A Systematic Review.

Long C, Amoasii L, Bassel-Duby R, Olson EN.

JAMA Neurol. 2016 Nov 1;73(11):1349-1355. doi: 10.1001/jamaneurol.2016.3388. Review.

27.

Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.

Lodka D, Pahuja A, Geers-Knörr C, Scheibe RJ, Nowak M, Hamati J, Köhncke C, Purfürst B, Kanashova T, Schmidt S, Glass DJ, Morano I, Heuser A, Kraft T, Bassel-Duby R, Olson EN, Dittmar G, Sommer T, Fielitz J.

J Cachexia Sarcopenia Muscle. 2016 May;7(2):165-80. doi: 10.1002/jcsm.12057. Epub 2015 Sep 7.

28.

Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106.

Anderson DM, Cannavino J, Li H, Anderson KM, Nelson BR, McAnally J, Bezprozvannaya S, Liu Y, Lin W, Liu N, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4494-503. doi: 10.1073/pnas.1608423113. Epub 2016 Jul 14.

29.

Myocardin-related transcription factors are required for skeletal muscle development.

Cenik BK, Liu N, Chen B, Bezprozvannaya S, Olson EN, Bassel-Duby R.

Development. 2016 Aug 1;143(15):2853-61. doi: 10.1242/dev.135855. Epub 2016 Jul 6.

30.

A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism.

Amoasii L, Holland W, Sanchez-Ortiz E, Baskin KK, Pearson M, Burgess SC, Nelson BR, Bassel-Duby R, Olson EN.

Genes Dev. 2016 Feb 15;30(4):434-46. doi: 10.1101/gad.273128.115.

31.

Structure-function analysis of myomaker domains required for myoblast fusion.

Millay DP, Gamage DG, Quinn ME, Min YL, Mitani Y, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2116-21. doi: 10.1073/pnas.1600101113. Epub 2016 Feb 8.

32.

A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle.

Nelson BR, Makarewich CA, Anderson DM, Winders BR, Troupes CD, Wu F, Reese AL, McAnally JR, Chen X, Kavalali ET, Cannon SC, Houser SR, Bassel-Duby R, Olson EN.

Science. 2016 Jan 15;351(6270):271-5. doi: 10.1126/science.aad4076.

33.

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy.

Long C, Amoasii L, Mireault AA, McAnally JR, Li H, Sanchez-Ortiz E, Bhattacharyya S, Shelton JM, Bassel-Duby R, Olson EN.

Science. 2016 Jan 22;351(6271):400-3. doi: 10.1126/science.aad5725. Epub 2015 Dec 31.

34.

A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9.

Carroll KJ, Makarewich CA, McAnally J, Anderson DM, Zentilin L, Liu N, Giacca M, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):338-43. doi: 10.1073/pnas.1523918113. Epub 2015 Dec 30.

35.

Myocardin-related transcription factors are required for cardiac development and function.

Mokalled MH, Carroll KJ, Cenik BK, Chen B, Liu N, Olson EN, Bassel-Duby R.

Dev Biol. 2015 Oct 15;406(2):109-16. doi: 10.1016/j.ydbio.2015.09.006. Epub 2015 Sep 16.

36.

Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes.

Zhou H, Dickson ME, Kim MS, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11864-9. doi: 10.1073/pnas.1516237112. Epub 2015 Sep 9.

37.

Angiotensin II Induces Skeletal Muscle Atrophy by Activating TFEB-Mediated MuRF1 Expression.

Du Bois P, Pablo Tortola C, Lodka D, Kny M, Schmidt F, Song K, Schmidt S, Bassel-Duby R, Olson EN, Fielitz J.

Circ Res. 2015 Aug 14;117(5):424-36. doi: 10.1161/CIRCRESAHA.114.305393. Epub 2015 Jul 2.

38.

hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function.

Ye J, Beetz N, O'Keeffe S, Tapia JC, Macpherson L, Chen WV, Bassel-Duby R, Olson EN, Maniatis T.

Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):E3020-9. doi: 10.1073/pnas.1508461112. Epub 2015 May 26.

39.

Severe myopathy in mice lacking the MEF2/SRF-dependent gene leiomodin-3.

Cenik BK, Garg A, McAnally JR, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN, Liu N.

J Clin Invest. 2015 Apr;125(4):1569-78. doi: 10.1172/JCI80115. Epub 2015 Mar 16.

40.

A micropeptide encoded by a putative long noncoding RNA regulates muscle performance.

Anderson DM, Anderson KM, Chang CL, Makarewich CA, Nelson BR, McAnally JR, Kasaragod P, Shelton JM, Liou J, Bassel-Duby R, Olson EN.

Cell. 2015 Feb 12;160(4):595-606. doi: 10.1016/j.cell.2015.01.009. Epub 2015 Jan 29.

41.

MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver.

Baskin KK, Grueter CE, Kusminski CM, Holland WL, Bookout AL, Satapati S, Kong YM, Burgess SC, Malloy CR, Scherer PE, Newgard CB, Bassel-Duby R, Olson EN.

EMBO Mol Med. 2014 Dec;6(12):1610-21. doi: 10.15252/emmm.201404218.

42.

Regulation of skeletal muscle development and disease by microRNAs.

Liu N, Bassel-Duby R.

Results Probl Cell Differ. 2015;56:165-90. doi: 10.1007/978-3-662-44608-9_8. Review.

PMID:
25344671
43.

Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors.

Nam YJ, Lubczyk C, Bhakta M, Zang T, Fernandez-Perez A, McAnally J, Bassel-Duby R, Olson EN, Munshi NV.

Development. 2014 Nov;141(22):4267-78. doi: 10.1242/dev.114025. Epub 2014 Oct 24.

44.

FHL2 regulates the resolution of tissue damage in chronic inflammatory arthritis.

Wixler V, Cromme C, Retser E, Meyer LH, Smyth N, Mühlenberg K, Korb-Pap A, Koers-Wunrau C, Sotsios Y, Bassel-Duby R, Baeten D, Tak PP, Niederreiter B, Redlich K, Bertrand J, Skryabin BV, Ludwig S, Pap T.

Ann Rheum Dis. 2015 Dec;74(12):2216-23. doi: 10.1136/annrheumdis-2013-205061. Epub 2014 Aug 14.

PMID:
25125695
45.

Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA.

Long C, McAnally JR, Shelton JM, Mireault AA, Bassel-Duby R, Olson EN.

Science. 2014 Sep 5;345(6201):1184-1188. doi: 10.1126/science.1254445. Epub 2014 Aug 14.

46.

Myomaker is essential for muscle regeneration.

Millay DP, Sutherland LB, Bassel-Duby R, Olson EN.

Genes Dev. 2014 Aug 1;28(15):1641-6. doi: 10.1101/gad.247205.114.

47.

Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor.

Long C, Grueter CE, Song K, Qin S, Qi X, Kong YM, Shelton JM, Richardson JA, Zhang CL, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11521-6. doi: 10.1073/pnas.1411251111. Epub 2014 Jul 21.

48.

Heart- and muscle-derived signaling system dependent on MED13 and Wingless controls obesity in Drosophila.

Lee JH, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9491-6. doi: 10.1073/pnas.1409427111. Epub 2014 Jun 16.

49.

KLHL40 deficiency destabilizes thin filament proteins and promotes nemaline myopathy.

Garg A, O'Rourke J, Long C, Doering J, Ravenscroft G, Bezprozvannaya S, Nelson BR, Beetz N, Li L, Chen S, Laing NG, Grange RW, Bassel-Duby R, Olson EN.

J Clin Invest. 2014 Aug;124(8):3529-39. doi: 10.1172/JCI74994. Epub 2014 Jun 24.

50.

Requirement of MEF2A, C, and D for skeletal muscle regeneration.

Liu N, Nelson BR, Bezprozvannaya S, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4109-14. doi: 10.1073/pnas.1401732111. Epub 2014 Mar 3.

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