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Items: 48


Protein kinases in mitotic phosphorylation of budding yeast CENP-A.

Mishra PK, Basrai MA.

Curr Genet. 2019 Dec;65(6):1325-1332. doi: 10.1007/s00294-019-00997-5. Epub 2019 May 22. Review.


Cell cycle-dependent association of polo kinase Cdc5 with CENP-A contributes to faithful chromosome segregation in budding yeast.

Mishra PK, Olafsson G, Boeckmann L, Westlake TJ, Jowhar ZM, Dittman LE, Baker RE, D'Amours D, Thorpe PH, Basrai MA.

Mol Biol Cell. 2019 Apr 1;30(8):1020-1036. doi: 10.1091/mbc.E18-09-0584. Epub 2019 Feb 6.


SUMO-Targeted Ubiquitin Ligases (STUbLs) Reduce the Toxicity and Abnormal Transcriptional Activity Associated With a Mutant, Aggregation-Prone Fragment of Huntingtin.

Ohkuni K, Pasupala N, Peek J, Holloway GL, Sclar GD, Levy-Myers R, Baker RE, Basrai MA, Kerscher O.

Front Genet. 2018 Sep 18;9:379. doi: 10.3389/fgene.2018.00379. eCollection 2018.


A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A.

Ciftci-Yilmaz S, Au WC, Mishra PK, Eisenstatt JR, Chang J, Dawson AR, Zhu I, Rahman M, Bilke S, Costanzo M, Baryshnikova A, Myers CL, Meltzer PS, Landsman D, Baker RE, Boone C, Basrai MA.

Genetics. 2018 Sep;210(1):203-218. doi: 10.1534/genetics.118.301305. Epub 2018 Jul 16.


N-terminal Sumoylation of Centromeric Histone H3 Variant Cse4 Regulates Its Proteolysis To Prevent Mislocalization to Non-centromeric Chromatin.

Ohkuni K, Levy-Myers R, Warren J, Au WC, Takahashi Y, Baker RE, Basrai MA.

G3 (Bethesda). 2018 Mar 28;8(4):1215-1223. doi: 10.1534/g3.117.300419.


Budding yeast CENP-ACse4 interacts with the N-terminus of Sgo1 and regulates its association with centromeric chromatin.

Mishra PK, Thapa KS, Chen P, Wang S, Hazbun TR, Basrai MA.

Cell Cycle. 2018;17(1):11-23. doi: 10.1080/15384101.2017.1380129. Epub 2018 Jan 2.


Mislocalization of centromeric histone H3 variant CENP-A contributes to chromosomal instability (CIN) in human cells.

Shrestha RL, Ahn GS, Staples MI, Sathyan KM, Karpova TS, Foltz DR, Basrai MA.

Oncotarget. 2017 Jul 18;8(29):46781-46800. doi: 10.18632/oncotarget.18108.


Polo kinase Cdc5 associates with centromeres to facilitate the removal of centromeric cohesin during mitosis.

Mishra PK, Ciftci-Yilmaz S, Reynolds D, Au WC, Boeckmann L, Dittman LE, Jowhar Z, Pachpor T, Yeh E, Baker RE, Hoyt MA, D'Amours D, Bloom K, Basrai MA.

Mol Biol Cell. 2016 Jul 15;27(14):2286-300. doi: 10.1091/mbc.E16-01-0004. Epub 2016 May 25.


SUMO-Targeted Ubiquitin Ligase (STUbL) Slx5 regulates proteolysis of centromeric histone H3 variant Cse4 and prevents its mislocalization to euchromatin.

Ohkuni K, Takahashi Y, Fulp A, Lawrimore J, Au WC, Pasupala N, Levy-Myers R, Warren J, Strunnikov A, Baker RE, Kerscher O, Bloom K, Basrai MA.

Mol Biol Cell. 2016 Mar 9. pii: mbc.E15-12-0827. [Epub ahead of print]


A Genome-Wide Screen with Nicotinamide to Identify Sirtuin-Dependent Pathways in Saccharomyces cerevisiae.

Choy JS, Qadri B, Henry L, Shroff K, Bifarin O, Basrai MA.

G3 (Bethesda). 2015 Dec 8;6(2):485-94. doi: 10.1534/g3.115.022244.


Pat1 protects centromere-specific histone H3 variant Cse4 from Psh1-mediated ubiquitination.

Mishra PK, Guo J, Dittman LE, Haase J, Yeh E, Bloom K, Basrai MA.

Mol Biol Cell. 2015 Jun 1;26(11):2067-79. doi: 10.1091/mbc.E14-08-1335. Epub 2015 Apr 1.


A 3D map of the yeast kinetochore reveals the presence of core and accessory centromere-specific histone.

Haase J, Mishra PK, Stephens A, Haggerty R, Quammen C, Taylor RM 2nd, Yeh E, Basrai MA, Bloom K.

Curr Biol. 2013 Oct 7;23(19):1939-44. doi: 10.1016/j.cub.2013.07.083. Epub 2013 Sep 26.


Cytoplasmic localization of Hug1p, a negative regulator of the MEC1 pathway, coincides with the compartmentalization of Rnr2p-Rnr4p.

Ainsworth WB, Hughes BT, Au WC, Sakelaris S, Kerscher O, Benton MG, Basrai MA.

Biochem Biophys Res Commun. 2013 Oct 4;439(4):443-8. doi: 10.1016/j.bbrc.2013.08.089. Epub 2013 Sep 5.


Yeast hEST1A/B (SMG5/6)-like proteins contribute to environment-sensing adaptive gene expression responses.

Lai X, Beilharz T, Au WC, Hammet A, Preiss T, Basrai MA, Heierhorst J.

G3 (Bethesda). 2013 Oct 3;3(10):1649-59. doi: 10.1534/g3.113.006924.


Structural integrity of centromeric chromatin and faithful chromosome segregation requires Pat1.

Mishra PK, Ottmann AR, Basrai MA.

Genetics. 2013 Oct;195(2):369-79. doi: 10.1534/genetics.113.155291. Epub 2013 Jul 26.


Genome-wide haploinsufficiency screen reveals a novel role for γ-TuSC in spindle organization and genome stability.

Choy JS, O'Toole E, Schuster BM, Crisp MJ, Karpova TS, McNally JG, Winey M, Gardner MK, Basrai MA.

Mol Biol Cell. 2013 Sep;24(17):2753-63. doi: 10.1091/mbc.E12-12-0902. Epub 2013 Jul 3.


Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae.

Boeckmann L, Takahashi Y, Au WC, Mishra PK, Choy JS, Dawson AR, Szeto MY, Waybright TJ, Heger C, McAndrew C, Goldsmith PK, Veenstra TD, Baker RE, Basrai MA.

Mol Biol Cell. 2013 Jun;24(12):2034-44. doi: 10.1091/mbc.E12-12-0893. Epub 2013 May 1.


A novel role of the N terminus of budding yeast histone H3 variant Cse4 in ubiquitin-mediated proteolysis.

Au WC, Dawson AR, Rawson DW, Taylor SB, Baker RE, Basrai MA.

Genetics. 2013 Jun;194(2):513-8. doi: 10.1534/genetics.113.149898. Epub 2013 Mar 22.


Insights into assembly and regulation of centromeric chromatin in Saccharomyces cerevisiae.

Choy JS, Mishra PK, Au WC, Basrai MA.

Biochim Biophys Acta. 2012 Jul;1819(7):776-83. doi: 10.1016/j.bbagrm.2012.02.008. Epub 2012 Feb 16. Review.


Mutability and mutational spectrum of chromosome transmission fidelity genes.

Stirling PC, Crisp MJ, Basrai MA, Tucker CM, Dunham MJ, Spencer FA, Hieter P.

Chromosoma. 2012 Jun;121(3):263-75. doi: 10.1007/s00412-011-0356-3. Epub 2011 Dec 24.


Misregulation of Scm3p/HJURP causes chromosome instability in Saccharomyces cerevisiae and human cells.

Mishra PK, Au WC, Choy JS, Kuich PH, Baker RE, Foltz DR, Basrai MA.

PLoS Genet. 2011 Sep;7(9):e1002303. doi: 10.1371/journal.pgen.1002303. Epub 2011 Sep 29.


A role for histone H4K16 hypoacetylation in Saccharomyces cerevisiae kinetochore function.

Choy JS, Acuña R, Au WC, Basrai MA.

Genetics. 2011 Sep;189(1):11-21. doi: 10.1534/genetics.111.130781. Epub 2011 Jun 6.


Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell.

Magtanong L, Ho CH, Barker SL, Jiao W, Baryshnikova A, Bahr S, Smith AM, Heisler LE, Choy JS, Kuzmin E, Andrusiak K, Kobylianski A, Li Z, Costanzo M, Basrai MA, Giaever G, Nislow C, Andrews B, Boone C.

Nat Biotechnol. 2011 May 15;29(6):505-11. doi: 10.1038/nbt.1855.


Gga2 mediates sequential ubiquitin-independent and ubiquitin-dependent steps in the trafficking of ARN1 from the trans-Golgi network to the vacuole.

Deng Y, Guo Y, Watson H, Au WC, Shakoury-Elizeh M, Basrai MA, Bonifacino JS, Philpott CC.

J Biol Chem. 2009 Aug 28;284(35):23830-41. doi: 10.1074/jbc.M109.030015. Epub 2009 Jul 1.


Altered dosage and mislocalization of histone H3 and Cse4p lead to chromosome loss in Saccharomyces cerevisiae.

Au WC, Crisp MJ, DeLuca SZ, Rando OJ, Basrai MA.

Genetics. 2008 May;179(1):263-75. doi: 10.1534/genetics.108.088518. Epub 2008 May 5.


Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae.

Kastenmayer JP, Ni L, Chu A, Kitchen LE, Au WC, Yang H, Carter CD, Wheeler D, Davis RW, Boeke JD, Snyder MA, Basrai MA.

Genome Res. 2006 Mar;16(3):365-73.


The C-terminal half of Saccharomyces cerevisiae Mad1p mediates spindle checkpoint function, chromosome transmission fidelity and CEN association.

Kastenmayer JP, Lee MS, Hong AL, Spencer FA, Basrai MA.

Genetics. 2005 Jun;170(2):509-17. Epub 2005 Mar 31.


Reconstitution of papillomavirus E2-mediated plasmid maintenance in Saccharomyces cerevisiae by the Brd4 bromodomain protein.

Brannon AR, Maresca JA, Boeke JD, Basrai MA, McBride AA.

Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2998-3003. Epub 2005 Feb 14.


Functional roles for evolutionarily conserved Spt4p at centromeres and heterochromatin in Saccharomyces cerevisiae.

Crotti LB, Basrai MA.

EMBO J. 2004 Apr 21;23(8):1804-14. Epub 2004 Apr 1. Erratum in: EMBO J. 2011;30(13):2749.


The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint.

Iouk T, Kerscher O, Scott RJ, Basrai MA, Wozniak RW.

J Cell Biol. 2002 Dec 9;159(5):807-19. Epub 2002 Dec 9.


Transcriptome analysis of Saccharomyces cerevisiae using serial analysis of gene expression.

Basrai MA, Hieter P.

Methods Enzymol. 2002;350:414-44. No abstract available.


Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation.

Kerscher O, Hieter P, Winey M, Basrai MA.

Genetics. 2001 Apr;157(4):1543-53.


Characterization of the CHD family of proteins.

Woodage T, Basrai MA, Baxevanis AD, Hieter P, Collins FS.

Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11472-7.


Small open reading frames: beautiful needles in the haystack.

Basrai MA, Hieter P, Boeke JD.

Genome Res. 1997 Aug;7(8):768-71. No abstract available.


Characterization of the yeast transcriptome.

Velculescu VE, Zhang L, Zhou W, Vogelstein J, Basrai MA, Bassett DE Jr, Hieter P, Vogelstein B, Kinzler KW.

Cell. 1997 Jan 24;88(2):243-51.


Exploiting the complete yeast genome sequence.

Bassett DE Jr, Basrai MA, Connelly C, Hyland KM, Kitagawa K, Mayer ML, Morrow DM, Page AM, Resto VA, Skibbens RV, Hieter P.

Curr Opin Genet Dev. 1996 Dec;6(6):763-6. Review.


Identification and analysis of a functional human homolog of the SPT4 gene of Saccharomyces cerevisiae.

Hartzog GA, Basrai MA, Ricupero-Hovasse SL, Hieter P, Winston F.

Mol Cell Biol. 1996 Jun;16(6):2848-56.


Faithful chromosome transmission requires Spt4p, a putative regulator of chromatin structure in Saccharomyces cerevisiae.

Basrai MA, Kingsbury J, Koshland D, Spencer F, Hieter P.

Mol Cell Biol. 1996 Jun;16(6):2838-47.


Is there a unique form of chromatin at the Saccharomyces cerevisiae centromeres?

Basrai MA, Hieter P.

Bioessays. 1995 Aug;17(8):669-72. Review.


Cloning of a Candida albicans peptide transport gene.

Basrai MA, Lubkowitz MA, Perry JR, Miller D, Krainer E, Naider F, Becker JM.

Microbiology. 1995 May;141 ( Pt 5):1147-56.


Isolation and characterization of a Saccharomyces cerevisiae peptide transport gene.

Perry JR, Basrai MA, Steiner HY, Naider F, Becker JM.

Mol Cell Biol. 1994 Jan;14(1):104-15.


Toxicity of oxalysine and oxalysine-containing peptides against Candida albicans: regulation of peptide transport by amino acids.

Basrai MA, Zhang HL, Miller D, Naider F, Becker JM.

J Gen Microbiol. 1992 Nov;138(11):2353-62.


Internalization of lucifer yellow in Candida albicans by fluid phase endocytosis.

Basrai MA, Naider F, Becker JM.

J Gen Microbiol. 1990 Jun;136(6):1059-65.


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