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Items: 1 to 50 of 189

1.

CRISPR-induced double-strand breaks trigger recombination between homologous chromosome arms.

Brunner E, Yagi R, Debrunner M, Beck-Schneider D, Burger A, Escher E, Mosimann C, Hausmann G, Basler K.

Life Sci Alliance. 2019 Jun 13;2(3). pii: e201800267. doi: 10.26508/lsa.201800267. Print 2019 Jun.

2.

Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner.

Zurkirchen L, Varum S, Giger S, Klug A, Häusel J, Bossart R, Zemke M, Cantù C, Atak ZK, Zamboni N, Basler K, Sommer L.

Nat Commun. 2019 May 16;10(1):2192. doi: 10.1038/s41467-019-09823-5.

3.

A Comprehensive Drosophila melanogaster Transcription Factor Interactome.

Shokri L, Inukai S, Hafner A, Weinand K, Hens K, Vedenko A, Gisselbrecht SS, Dainese R, Bischof J, Furger E, Feuz JD, Basler K, Deplancke B, Bulyk ML.

Cell Rep. 2019 Apr 16;27(3):955-970.e7. doi: 10.1016/j.celrep.2019.03.071.

4.

Is there a female cycle of violence after exposure to childhood maltreatment? A meta-analysis.

Augsburger M, Basler K, Maercker A.

Psychol Med. 2019 Apr 17:1-11. doi: 10.1017/S0033291719000680. [Epub ahead of print]

PMID:
30994081
5.

Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation.

Varum S, Baggiolini A, Zurkirchen L, Atak ZK, Cantù C, Marzorati E, Bossart R, Wouters J, Häusel J, Tuncer E, Zingg D, Veen D, John N, Balz M, Levesque MP, Basler K, Aerts S, Zamboni N, Dummer R, Sommer L.

Cell Stem Cell. 2019 Apr 4;24(4):637-653.e9. doi: 10.1016/j.stem.2019.03.011.

PMID:
30951662
6.

Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche.

Salazar VS, Capelo LP, Cantù C, Zimmerli D, Gosalia N, Pregizer S, Cox K, Ohte S, Feigenson M, Gamer L, Nyman JS, Carey DJ, Economides A, Basler K, Rosen V.

Elife. 2019 Feb 8;8. pii: e42386. doi: 10.7554/eLife.42386.

7.

Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and tumor regression.

Kabakci Z, Käppeli S, Cantù C, Jensen LD, König C, Toggweiler J, Gentili C, Ribaudo G, Zagotto G, Basler K, Pinna LA, Cozza G, Ferrari S.

Sci Rep. 2019 Feb 4;9(1):1335. doi: 10.1038/s41598-019-38579-7.

8.

Endoscopic cricopharyngeal myotomy in infants.

Basler KJ, Swanson C, Andreoli SM.

Int J Pediatr Otorhinolaryngol. 2019 Jan;116:15-17. doi: 10.1016/j.ijporl.2018.09.034. Epub 2018 Oct 2.

PMID:
30554687
9.

Xrp1 is a transcription factor required for cell competition-driven elimination of loser cells.

Baillon L, Germani F, Rockel C, Hilchenbach J, Basler K.

Sci Rep. 2018 Dec 7;8(1):17712. doi: 10.1038/s41598-018-36277-4.

10.

The Toll pathway inhibits tissue growth and regulates cell fitness in an infection-dependent manner.

Germani F, Hain D, Sternlicht D, Moreno E, Basler K.

Elife. 2018 Nov 19;7. pii: e39939. doi: 10.7554/eLife.39939.

11.

TCF/LEF dependent and independent transcriptional regulation of Wnt/β-catenin target genes.

Doumpas N, Lampart F, Robinson MD, Lentini A, Nestor CE, Cantù C, Basler K.

EMBO J. 2019 Jan 15;38(2). pii: e98873. doi: 10.15252/embj.201798873. Epub 2018 Nov 13.

PMID:
30425074
12.

Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling.

Cantù C, Felker A, Zimmerli D, Prummel KD, Cabello EM, Chiavacci E, Méndez-Acevedo KM, Kirchgeorg L, Burger S, Ripoll J, Valenta T, Hausmann G, Vilain N, Aguet M, Burger A, Panáková D, Basler K, Mosimann C.

Genes Dev. 2018 Nov 1;32(21-22):1443-1458. doi: 10.1101/gad.315531.118. Epub 2018 Oct 26.

13.

Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila.

Bischof J, Duffraisse M, Furger E, Ajuria L, Giraud G, Vanderperre S, Paul R, Björklund M, Ahr D, Ahmed AW, Spinelli L, Brun C, Basler K, Merabet S.

Elife. 2018 Sep 24;7. pii: e38853. doi: 10.7554/eLife.38853.

14.

Myocardial β-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation.

Wang Y, Lu P, Wu B, Riascos-Bernal DF, Sibinga NES, Valenta T, Basler K, Zhou B.

J Mol Cell Cardiol. 2018 Oct;123:150-158. doi: 10.1016/j.yjmcc.2018.09.001. Epub 2018 Sep 8.

PMID:
30201295
15.

EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.

Zingg D, Debbache J, Peña-Hernández R, Antunes AT, Schaefer SM, Cheng PF, Zimmerli D, Haeusel J, Calçada RR, Tuncer E, Zhang Y, Bossart R, Wong KK, Basler K, Dummer R, Santoro R, Levesque MP, Sommer L.

Cancer Cell. 2018 Jul 9;34(1):69-84.e14. doi: 10.1016/j.ccell.2018.06.001. Epub 2018 Jun 28.

16.

GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells.

Degirmenci B, Valenta T, Dimitrieva S, Hausmann G, Basler K.

Nature. 2018 Jun;558(7710):449-453. doi: 10.1038/s41586-018-0190-3. Epub 2018 Jun 6.

PMID:
29875413
17.

A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle.

Spletter ML, Barz C, Yeroslaviz A, Zhang X, Lemke SB, Bonnard A, Brunner E, Cardone G, Basler K, Habermann BH, Schnorrer F.

Elife. 2018 May 30;7. pii: e34058. doi: 10.7554/eLife.34058.

18.

WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma.

Zimmerli D, Cecconi V, Valenta T, Hausmann G, Cantù C, Restivo G, Hafner J, Basler K, van den Broek M.

Oncogene. 2018 Jul;37(27):3753-3762. doi: 10.1038/s41388-018-0244-x. Epub 2018 Apr 17.

19.

Wnt Ligands as a Part of the Stem Cell Niche in the Intestine and the Liver.

Degirmenci B, Hausmann G, Valenta T, Basler K.

Prog Mol Biol Transl Sci. 2018 Jan;153:1-19. doi: 10.1016/bs.pmbts.2017.11.011. Epub 2018 Jan 8. Review.

PMID:
29389513
20.

Spontaneous Otorrhagia after Laparoscopic Pelvic Surgery: A Report of Two Cases.

Basler K, Malone A, Carmichael M, Hafez O, Padhya T, Boyev KP.

J Int Adv Otol. 2017 Dec;13(3):434-436. doi: 10.5152/iao.2017.3600. Epub 2017 Nov 2.

21.

Challenging FRET-based E-Cadherin force measurements in Drosophila.

Eder D, Basler K, Aegerter CM.

Sci Rep. 2017 Oct 20;7(1):13692. doi: 10.1038/s41598-017-14136-y.

22.

Generation of genome-modified Drosophila cell lines using SwAP.

Franz A, Brunner E, Basler K.

Fly (Austin). 2017 Oct 2;11(4):303-311. doi: 10.1080/19336934.2017.1372068. Epub 2017 Aug 30.

23.

Biphasic influence of Staphylococcus aureus on human epidermal tight junctions.

Bäsler K, Galliano MF, Bergmann S, Rohde H, Wladykowski E, Vidal-Y-Sy S, Guiraud B, Houdek P, Schüring G, Volksdorf T, Caruana A, Bessou-Touya S, Schneider SW, Duplan H, Brandner JM.

Ann N Y Acad Sci. 2017 Oct;1405(1):53-70. doi: 10.1111/nyas.13418. Epub 2017 Jul 28.

PMID:
28753223
24.

Combining Time-of-Flight Secondary Ion Mass Spectrometry Imaging Mass Spectrometry and CARS Microspectroscopy Reveals Lipid Patterns Reminiscent of Gene Expression Patterns in the Wing Imaginal Disc of Drosophila melanogaster.

Marty F, Rago G, Smith DF, Gao X, Eijkel GB, MacAleese L, Bonn M, Brunner E, Basler K, Heeren RMA.

Anal Chem. 2017 Sep 19;89(18):9664-9670. doi: 10.1021/acs.analchem.7b00125. Epub 2017 Aug 29.

25.

Dpp controls growth and patterning in Drosophila wing precursors through distinct modes of action.

Bosch PS, Ziukaite R, Alexandre C, Basler K, Vincent JP.

Elife. 2017 Jul 4;6. pii: e22546. doi: 10.7554/eLife.22546.

26.

Pharmacological interventions in the Wnt pathway: inhibition of Wnt secretion versus disrupting the protein-protein interfaces of nuclear factors.

Zimmerli D, Hausmann G, Cantù C, Basler K.

Br J Pharmacol. 2017 Dec;174(24):4600-4610. doi: 10.1111/bph.13864. Epub 2017 Jun 16. Review.

27.

Probing the canonicity of the Wnt/Wingless signaling pathway.

Franz A, Shlyueva D, Brunner E, Stark A, Basler K.

PLoS Genet. 2017 Apr 3;13(4):e1006700. doi: 10.1371/journal.pgen.1006700. eCollection 2017 Apr.

28.

A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation.

Cantù C, Pagella P, Shajiei TD, Zimmerli D, Valenta T, Hausmann G, Basler K, Mitsiadis TA.

Sci Signal. 2017 Feb 7;10(465). pii: eaah4598. doi: 10.1126/scisignal.aah4598.

29.

Drosophila DDX3/Belle Exerts Its Function Outside of the Wnt/Wingless Signaling Pathway.

Jenny FH, Basler K.

PLoS One. 2016 Dec 28;11(12):e0166862. doi: 10.1371/journal.pone.0166862. eCollection 2016.

30.

Forces controlling organ growth and size.

Eder D, Aegerter C, Basler K.

Mech Dev. 2017 Apr;144(Pt A):53-61. doi: 10.1016/j.mod.2016.11.005. Epub 2016 Nov 30. Review.

31.

Tight junctions in skin inflammation.

Bäsler K, Brandner JM.

Pflugers Arch. 2017 Jan;469(1):3-14. doi: 10.1007/s00424-016-1903-9. Epub 2016 Nov 16. Review.

PMID:
27853878
32.

Cultivation and Live Imaging of Drosophila Imaginal Discs.

Restrepo S, Zartman JJ, Basler K.

Methods Mol Biol. 2016;1478:203-213. Review.

PMID:
27730583
33.

The transcription factor Ets21C drives tumor growth by cooperating with AP-1.

Toggweiler J, Willecke M, Basler K.

Sci Rep. 2016 Oct 7;6:34725. doi: 10.1038/srep34725.

34.

The role of tight junctions in skin barrier function and dermal absorption.

Bäsler K, Bergmann S, Heisig M, Naegel A, Zorn-Kruppa M, Brandner JM.

J Control Release. 2016 Nov 28;242:105-118. doi: 10.1016/j.jconrel.2016.08.007. Epub 2016 Aug 10. Review.

PMID:
27521894
35.
36.

β-Catenin C-terminal signals suppress p53 and are essential for artery formation.

Riascos-Bernal DF, Chinnasamy P, Cao LL, Dunaway CM, Valenta T, Basler K, Sibinga NE.

Nat Commun. 2016 Aug 8;7:12389. doi: 10.1038/ncomms12389.

37.

A novel role for the tumour suppressor Nitrilase1 modulating the Wnt/β-catenin signalling pathway.

Mittag S, Valenta T, Weiske J, Bloch L, Klingel S, Gradl D, Wetzel F, Chen Y, Petersen I, Basler K, Huber O.

Cell Discov. 2016 Jan 5;2:15039. doi: 10.1038/celldisc.2015.39. eCollection 2016.

38.

Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis.

Valenta T, Degirmenci B, Moor AE, Herr P, Zimmerli D, Moor MB, Hausmann G, Cantù C, Aguet M, Basler K.

Cell Rep. 2016 May 3;15(5):911-918. doi: 10.1016/j.celrep.2016.03.088. Epub 2016 Apr 21.

39.

Transforming growth factor-β-dependent Wnt secretion controls myofibroblast formation and myocardial fibrosis progression in experimental autoimmune myocarditis.

Blyszczuk P, Müller-Edenborn B, Valenta T, Osto E, Stellato M, Behnke S, Glatz K, Basler K, Lüscher TF, Distler O, Eriksson U, Kania G.

Eur Heart J. 2017 May 7;38(18):1413-1425. doi: 10.1093/eurheartj/ehw116.

PMID:
27099262
40.

BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer.

Moor AE, Anderle P, Cantù C, Rodriguez P, Wiedemann N, Baruthio F, Deka J, André S, Valenta T, Moor MB, Győrffy B, Barras D, Delorenzi M, Basler K, Aguet M.

EBioMedicine. 2015 Oct 30;2(12):1932-43. doi: 10.1016/j.ebiom.2015.10.030. eCollection 2015 Dec.

41.

EpiTools: An Open-Source Image Analysis Toolkit for Quantifying Epithelial Growth Dynamics.

Heller D, Hoppe A, Restrepo S, Gatti L, Tournier AL, Tapon N, Basler K, Mao Y.

Dev Cell. 2016 Jan 11;36(1):103-116. doi: 10.1016/j.devcel.2015.12.012.

42.

Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation.

Zemke M, Draganova K, Klug A, Schöler A, Zurkirchen L, Gay MH, Cheng P, Koseki H, Valenta T, Schübeler D, Basler K, Sommer L.

BMC Biol. 2015 Nov 30;13:103. doi: 10.1186/s12915-015-0210-9.

43.

MorphoGraphX: A platform for quantifying morphogenesis in 4D.

Barbier de Reuille P, Routier-Kierzkowska AL, Kierzkowski D, Bassel GW, Schüpbach T, Tauriello G, Bajpai N, Strauss S, Weber A, Kiss A, Burian A, Hofhuis H, Sapala A, Lipowczan M, Heimlicher MB, Robinson S, Bayer EM, Basler K, Koumoutsakos P, Roeder AH, Aegerter-Wilmsen T, Nakayama N, Tsiantis M, Hay A, Kwiatkowska D, Xenarios I, Kuhlemeier C, Smith RS.

Elife. 2015 May 6;4:05864. doi: 10.7554/eLife.05864.

44.

Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation.

Gay MH, Valenta T, Herr P, Paratore-Hari L, Basler K, Sommer L.

BMC Biol. 2015 Apr 11;13:24. doi: 10.1186/s12915-015-0134-4.

45.

The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth.

Andersen DS, Colombani J, Palmerini V, Chakrabandhu K, Boone E, Röthlisberger M, Toggweiler J, Basler K, Mapelli M, Hueber AO, Léopold P.

Nature. 2015 Jun 25;522(7557):482-6. doi: 10.1038/nature14298. Epub 2015 Apr 15.

PMID:
25874673
46.

Canonical wnt signaling regulates atrioventricular junction programming and electrophysiological properties.

Gillers BS, Chiplunkar A, Aly H, Valenta T, Basler K, Christoffels VM, Efimov IR, Boukens BJ, Rentschler S.

Circ Res. 2015 Jan 30;116(3):398-406. doi: 10.1161/CIRCRESAHA.116.304731. Epub 2014 Nov 6.

47.

A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development.

Schertel C, Albarca M, Rockel-Bauer C, Kelley NW, Bischof J, Hens K, van Nimwegen E, Basler K, Deplancke B.

Genome Res. 2015 Apr;25(4):514-23. doi: 10.1101/gr.181305.114. Epub 2015 Jan 7.

48.

Powerful Drosophila screens that paved the wingless pathway.

Jenny FH, Basler K.

Fly (Austin). 2014;8(4):218-25. doi: 10.4161/19336934.2014.985988. Epub 2015 Jan 20. Review.

49.

DIGESTIF: a universal quality standard for the control of bottom-up proteomics experiments.

Lebert D, Louwagie M, Goetze S, Picard G, Ossola R, Duquesne C, Basler K, Ferro M, Rinner O, Aebersold R, Garin J, Mouz N, Brunner E, Brun V.

J Proteome Res. 2015 Feb 6;14(2):787-803. doi: 10.1021/pr500834z. Epub 2014 Dec 30.

PMID:
25495225
50.

An ancient defense system eliminates unfit cells from developing tissues during cell competition.

Meyer SN, Amoyel M, Bergantiños C, de la Cova C, Schertel C, Basler K, Johnston LA.

Science. 2014 Dec 5;346(6214):1258236. doi: 10.1126/science.1258236.

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