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Items: 24


Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect against AKI.

Chiba T, Peasley KD, Cargill KR, Maringer KV, Bharathi SS, Mukherjee E, Zhang Y, Holtz A, Basisty N, Yagobian SD, Schilling B, Goetzman ES, Sims-Lucas S.

J Am Soc Nephrol. 2019 Oct 1. pii: ASN.2019020163. doi: 10.1681/ASN.2019020163. [Epub ahead of print]


SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells.

Wiley CD, Liu S, Limbad C, Zawadzka AM, Beck J, Demaria M, Artwood R, Alimirah F, Lopez-Dominguez JA, Kuehnemann C, Danielson SR, Basisty N, Kasler HG, Oron TR, Desprez PY, Mooney SD, Gibson BW, Schilling B, Campisi J, Kapahi P.

Cell Rep. 2019 Sep 24;28(13):3329-3337.e5. doi: 10.1016/j.celrep.2019.08.049.


Accumulation of "Old Proteins" and the Critical Need for MS-based Protein Turnover Measurements in Aging and Longevity.

Basisty N, Holtz A, Schilling B.

Proteomics. 2019 Aug 13:e1800403. doi: 10.1002/pmic.201800403. [Epub ahead of print] Review.


Post-translational Protein Acetylation: An Elegant Mechanism for Bacteria to Dynamically Regulate Metabolic Functions.

Christensen DG, Xie X, Basisty N, Byrnes J, McSweeney S, Schilling B, Wolfe AJ.

Front Microbiol. 2019 Jul 12;10:1604. doi: 10.3389/fmicb.2019.01604. eCollection 2019. Review.


Mechanisms, Detection, and Relevance of Protein Acetylation in Prokaryotes.

Christensen DG, Baumgartner JT, Xie X, Jew KM, Basisty N, Schilling B, Kuhn ML, Wolfe AJ.

MBio. 2019 Apr 9;10(2). pii: e02708-18. doi: 10.1128/mBio.02708-18. Review.


Global Lysine Acetylation in Escherichia coli Results from Growth Conditions That Favor Acetate Fermentation.

Schilling B, Basisty N, Christensen DG, Sorensen D, Orr JS, Wolfe AJ, Rao CV.

J Bacteriol. 2019 Apr 9;201(9). pii: e00768-18. doi: 10.1128/JB.00768-18. Print 2019 May 1.


Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose.

Meyer JG, Softic S, Basisty N, Rardin MJ, Verdin E, Gibson BW, Ilkayeva O, Newgard CB, Kahn CR, Schilling B.

PLoS One. 2018 Dec 26;13(12):e0208973. doi: 10.1371/journal.pone.0208973. eCollection 2018.


Identifying ubiquitinated proteins and aggregates.

Basisty N, Schilling B, Rabinovitch PS.

Aging (Albany NY). 2018 Oct 18;10(10):2549-2550. doi: 10.18632/aging.101605. No abstract available.


Simultaneous Quantification of the Acetylome and Succinylome by 'One-Pot' Affinity Enrichment.

Basisty N, Meyer JG, Wei L, Gibson BW, Schilling B.

Proteomics. 2018 Sep;18(17):e1800123. doi: 10.1002/pmic.201800123. Epub 2018 Aug 19.


Removing 4E-BP Enables Synapses to Refine without Postsynaptic Activity.

Chong Y, Saviuk N, Pie B, Basisty N, Quinn RK, Schilling B, Sonenberg N, Cooper E, Haghighi AP.

Cell Rep. 2018 Apr 3;23(1):11-22. doi: 10.1016/j.celrep.2018.03.040.


Protein Turnover in Aging and Longevity.

Basisty N, Meyer JG, Schilling B.

Proteomics. 2018 Mar;18(5-6):e1700108. doi: 10.1002/pmic.201700108. Review.


Stable Isotope Labeling Reveals Novel Insights Into Ubiquitin-Mediated Protein Aggregation With Age, Calorie Restriction, and Rapamycin Treatment.

Basisty NB, Liu Y, Reynolds J, Karunadharma PP, Dai DF, Fredrickson J, Beyer RP, MacCoss MJ, Rabinovitch PS.

J Gerontol A Biol Sci Med Sci. 2018 Apr 17;73(5):561-570. doi: 10.1093/gerona/glx047.


Mitochondrial-Targeted Catalase: Extended Longevity and the Roles in Various Disease Models.

Dai DF, Chiao YA, Martin GM, Marcinek DJ, Basisty N, Quarles EK, Rabinovitch PS.

Prog Mol Biol Transl Sci. 2017;146:203-241. doi: 10.1016/bs.pmbts.2016.12.015. Epub 2017 Feb 4. Review.


Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant.

Boominathan A, Vanhoozer S, Basisty N, Powers K, Crampton AL, Wang X, Friedricks N, Schilling B, Brand MD, O'Connor MS.

Nucleic Acids Res. 2016 Nov 2;44(19):9342-9357. Epub 2016 Sep 4.


Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: 'reverse' antagonistic pleiotropy?

Basisty N, Dai DF, Gagnidze A, Gitari L, Fredrickson J, Maina Y, Beyer RP, Emond MJ, Hsieh EJ, MacCoss MJ, Martin GM, Rabinovitch PS.

Aging Cell. 2016 Aug;15(4):634-45. doi: 10.1111/acel.12472. Epub 2016 Apr 8.


Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts.

Chiao YA, Kolwicz SC, Basisty N, Gagnidze A, Zhang J, Gu H, Djukovic D, Beyer RP, Raftery D, MacCoss M, Tian R, Rabinovitch PS.

Aging (Albany NY). 2016 Feb;8(2):314-27.


Age modifies respiratory complex I and protein homeostasis in a muscle type-specific manner.

Kruse SE, Karunadharma PP, Basisty N, Johnson R, Beyer RP, MacCoss MJ, Rabinovitch PS, Marcinek DJ.

Aging Cell. 2016 Feb;15(1):89-99. doi: 10.1111/acel.12412. Epub 2015 Oct 25.


Mitochondrial dysfunction in cardiac aging.

Tocchi A, Quarles EK, Basisty N, Gitari L, Rabinovitch PS.

Biochim Biophys Acta. 2015 Nov;1847(11):1424-33. doi: 10.1016/j.bbabio.2015.07.009. Epub 2015 Jul 17. Review.


Respiratory chain protein turnover rates in mice are highly heterogeneous but strikingly conserved across tissues, ages, and treatments.

Karunadharma PP, Basisty N, Chiao YA, Dai DF, Drake R, Levy N, Koh WJ, Emond MJ, Kruse S, Marcinek D, Maccoss MJ, Rabinovitch PS.

FASEB J. 2015 Aug;29(8):3582-92. doi: 10.1096/fj.15-272666. Epub 2015 May 14.


Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects.

Karunadharma PP, Basisty N, Dai DF, Chiao YA, Quarles EK, Hsieh EJ, Crispin D, Bielas JH, Ericson NG, Beyer RP, MacKay VL, MacCoss MJ, Rabinovitch PS.

Aging Cell. 2015 Aug;14(4):547-57. doi: 10.1111/acel.12317. Epub 2015 Mar 23.


Quality control systems in cardiac aging.

Quarles EK, Dai DF, Tocchi A, Basisty N, Gitari L, Rabinovitch PS.

Ageing Res Rev. 2015 Sep;23(Pt A):101-15. doi: 10.1016/j.arr.2015.02.003. Epub 2015 Feb 19. Review.


Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart.

Dai DF, Karunadharma PP, Chiao YA, Basisty N, Crispin D, Hsieh EJ, Chen T, Gu H, Djukovic D, Raftery D, Beyer RP, MacCoss MJ, Rabinovitch PS.

Aging Cell. 2014 Jun;13(3):529-39. doi: 10.1111/acel.12203. Epub 2014 Feb 25.


Global proteomics and pathway analysis of pressure-overload-induced heart failure and its attenuation by mitochondrial-targeted peptides.

Dai DF, Hsieh EJ, Chen T, Menendez LG, Basisty NB, Tsai L, Beyer RP, Crispin DA, Shulman NJ, Szeto HH, Tian R, MacCoss MJ, Rabinovitch PS.

Circ Heart Fail. 2013 Sep 1;6(5):1067-76. doi: 10.1161/CIRCHEARTFAILURE.113.000406. Epub 2013 Aug 9.


Composition and acidification of the culture medium influences chronological aging similarly in vineyard and laboratory yeast.

Murakami CJ, Wall V, Basisty N, Kaeberlein M.

PLoS One. 2011;6(9):e24530. doi: 10.1371/journal.pone.0024530. Epub 2011 Sep 19.

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