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Items: 17

1.

IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia.

Lopes BA, Meyer C, Barbosa TC, Poubel CP, Mansur MB, Duployez N, Bashton M, Harrison CJ, Zur Stadt U, Horstmann M, Pombo-de-Oliveira MS, Palmi C, Cazzaniga G, Venn NC, Sutton R, Alonso CN, Tsaur G, Gupta SK, Bakhshi S, Marschalek R, Emerenciano M.

Transl Oncol. 2019 May;12(5):726-732. doi: 10.1016/j.tranon.2019.02.002. Epub 2019 Mar 13.

2.

SH2B3 inactivation through CN-LOH 12q is uniquely associated with B-cell precursor ALL with iAMP21 or other chromosome 21 gain.

Sinclair PB, Ryan S, Bashton M, Hollern S, Hanna R, Case M, Schwalbe EC, Schwab CJ, Cranston RE, Young BD, Irving JAE, Vora AJ, Moorman AV, Harrison CJ.

Leukemia. 2019 Aug;33(8):1881-1894. doi: 10.1038/s41375-019-0412-1. Epub 2019 Feb 28.

PMID:
30816328
3.

High prevalence of focal and multi-focal somatic genetic variants in the human brain.

Keogh MJ, Wei W, Aryaman J, Walker L, van den Ameele J, Coxhead J, Wilson I, Bashton M, Beck J, West J, Chen R, Haudenschild C, Bartha G, Luo S, Morris CM, Jones NS, Attems J, Chinnery PF.

Nat Commun. 2018 Oct 15;9(1):4257. doi: 10.1038/s41467-018-06331-w.

4.

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.

Sinclair PB, Blair HH, Ryan SL, Buechler L, Cheng J, Clayton J, Hanna R, Hollern S, Hawking Z, Bashton M, Schwab CJ, Jones L, Russell LJ, Marr H, Carey P, Halsey C, Heidenreich O, Moorman AV, Harrison CJ.

Haematologica. 2018 Apr;103(4):634-644. doi: 10.3324/haematol.2017.172304. Epub 2018 Feb 15.

5.

Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures.

Schwalbe EC, Hicks D, Rafiee G, Bashton M, Gohlke H, Enshaei A, Potluri S, Matthiesen J, Mather M, Taleongpong P, Chaston R, Silmon A, Curtis A, Lindsey JC, Crosier S, Smith AJ, Goschzik T, Doz F, Rutkowski S, Lannering B, Pietsch T, Bailey S, Williamson D, Clifford SC.

Sci Rep. 2017 Oct 18;7(1):13421. doi: 10.1038/s41598-017-13644-1.

6.

The role of the RAS pathway in iAMP21-ALL.

Ryan SL, Matheson E, Grossmann V, Sinclair P, Bashton M, Schwab C, Towers W, Partington M, Elliott A, Minto L, Richardson S, Rahman T, Keavney B, Skinner R, Bown N, Haferlach T, Vandenberghe P, Haferlach C, Santibanez-Koref M, Moorman AV, Kohlmann A, Irving JA, Harrison CJ.

Leukemia. 2016 Sep;30(9):1824-31. doi: 10.1038/leu.2016.80. Epub 2016 Apr 22.

7.

DNA methylation profiling identifies novel markers of progression in hepatitis B-related chronic liver disease.

Zeybel M, Vatansever S, Hardy T, Sarı AA, Cakalağaoğlu F, Avcı A, Zeybel GL, Karahüseyinoğlu S, Bashton M, Mathers JC, Ünsal B, Mann J.

Clin Epigenetics. 2016 May 5;8:48. doi: 10.1186/s13148-016-0218-1. eCollection 2016.

8.

Critical roles of arginine in growth and biofilm development by Streptococcus gordonii.

Jakubovics NS, Robinson JC, Samarian DS, Kolderman E, Yassin SA, Bettampadi D, Bashton M, Rickard AH.

Mol Microbiol. 2015 Jul;97(2):281-300. doi: 10.1111/mmi.13023. Epub 2015 May 20.

9.

Crowdsourcing genomic analyses of ash and ash dieback - power to the people.

Maclean D, Yoshida K, Edwards A, Crossman L, Clavijo B, Clark M, Swarbreck D, Bashton M, Chapman P, Gijzen M, Caccamo M, Downie A, Kamoun S, Saunders DG.

Gigascience. 2013 Feb 12;2(1):2. doi: 10.1186/2047-217X-2-2.

10.

Domain-ligand mapping for enzymes.

Bashton M, Thornton JM.

J Mol Recognit. 2010 Mar-Apr;23(2):194-208. doi: 10.1002/jmr.992. Review.

PMID:
19810051
11.

Small Molecule Subgraph Detector (SMSD) toolkit.

Rahman SA, Bashton M, Holliday GL, Schrader R, Thornton JM.

J Cheminform. 2009 Aug 10;1(1):12. doi: 10.1186/1758-2946-1-12.

12.

PROCOGNATE: a cognate ligand domain mapping for enzymes.

Bashton M, Nobeli I, Thornton JM.

Nucleic Acids Res. 2008 Jan;36(Database issue):D618-22. Epub 2007 Aug 24.

13.

The generation of new protein functions by the combination of domains.

Bashton M, Chothia C.

Structure. 2007 Jan;15(1):85-99.

14.

Cognate ligand domain mapping for enzymes.

Bashton M, Nobeli I, Thornton JM.

J Mol Biol. 2006 Dec 8;364(4):836-52. Epub 2006 Sep 20.

PMID:
17034815
15.

Supra-domains: evolutionary units larger than single protein domains.

Vogel C, Berzuini C, Bashton M, Gough J, Teichmann SA.

J Mol Biol. 2004 Feb 20;336(3):809-23.

PMID:
15095989
16.

Structure, function and evolution of multidomain proteins.

Vogel C, Bashton M, Kerrison ND, Chothia C, Teichmann SA.

Curr Opin Struct Biol. 2004 Apr;14(2):208-16. Review.

PMID:
15093836
17.

The geometry of domain combination in proteins.

Bashton M, Chothia C.

J Mol Biol. 2002 Jan 25;315(4):927-39.

PMID:
11812158

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