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Items: 1 to 50 of 71

1.

Conductance studies on trichotoxin_A50E and implications for channel structure.

Duclohier H, Alder GM, Bashford CL, Brückner H, Chugh JK, Wallace BA.

Biophys J. 2004 Sep;87(3):1705-10.

2.

Ion permeation of pores in model membranes: selectivity, fluctuations and the role of surface charge.

Bashford CL.

Eur Biophys J. 2004 May;33(3):280-2. Epub 2003 Nov 4.

PMID:
14598001
3.

Understanding the tumor metabolic phenotype in the genomic era.

Stubbs M, Bashford CL, Griffiths JR.

Curr Mol Med. 2003 Feb;3(1):49-59.

PMID:
12558074
4.

Fluctuation of surface charge in membrane pores.

Bashford CL, Alder GM, Pasternak CA.

Biophys J. 2002 Apr;82(4):2032-40.

5.

A study of membrane activity in rat prostate cancer cells: an evaluation of the FM1-43 dye technique.

Mycielska ME, Schäfer M, Fraser SP, Djamgoz MB, Bashford CL.

Biosci Rep. 2000 Feb;20(1):31-40.

PMID:
10888409
6.

Structure-based prediction of the conductance properties of ion channels.

Smart OS, Coates GM, Sansom MS, Alder GM, Bashford CL.

Faraday Discuss. 1998;(111):185-99; discussion 225-46.

PMID:
10822609
7.

Causes and consequences of tumour acidity and implications for treatment.

Stubbs M, McSheehy PM, Griffiths JR, Bashford CL.

Mol Med Today. 2000 Jan;6(1):15-9. Review.

PMID:
10637570
8.

Using HOLE to predict the effects of PEG's on the conductance of alpha-toxin.

Coates GM, Bashford CL, Smart OS.

Biochem Soc Trans. 1998 Aug;26(3):S193. No abstract available.

PMID:
9765912
9.

Thermal control of drug release by a responsive ion track membrane observed by radio tracer flow dialysis.

Spohr R, Reber N, Wolf A, Alder GM, Ang V, Bashford CL, Pasternak CA, Omichi H, Yoshida M.

J Control Release. 1998 Jan 2;50(1-3):1-11.

PMID:
9685867
10.

Influence of pH on the uptake of 5-fluorouracil into isolated tumour cells.

Ojugo AS, McSheehy PM, Stubbs M, Alder G, Bashford CL, Maxwell RJ, Leach MO, Judson IR, Griffiths JR.

Br J Cancer. 1998 Mar;77(6):873-9.

11.

A conserved tryptophan in pneumolysin is a determinant of the characteristics of channels formed by pneumolysin in cells and planar lipid bilayers.

Korchev YE, Bashford CL, Pederzolli C, Pasternak CA, Morgan PJ, Andrew PW, Mitchell TJ.

Biochem J. 1998 Feb 1;329 ( Pt 3):571-7.

12.

Specialized scanning ion-conductance microscope for imaging of living cells.

Korchev YE, Milovanovic M, Bashford CL, Bennett DC, Sviderskaya EV, Vodyanoy I, Lab MJ.

J Microsc. 1997 Oct;188(Pt 1):17-23.

13.

Scanning ion conductance microscopy of living cells.

Korchev YE, Bashford CL, Milovanovic M, Vodyanoy I, Lab MJ.

Biophys J. 1997 Aug;73(2):653-8.

14.

A novel explanation for fluctuations of ion current through narrow pores.

Korchev YE, Bashford CL, Alder GM, Apel PY, Edmonds DT, Lev AA, Nandi K, Zima AV, Pasternak CA.

FASEB J. 1997 Jun;11(7):600-8.

PMID:
9212084
15.

31P-magnetic resonance spectroscopy studies of nucleated and non-nucleated erythrocytes; time domain data analysis (VARPRO) incorporating prior knowledge can give information on the binding of ADP.

Stubbs M, Van den Boogaart A, Bashford CL, Miranda PM, Rodrigues LM, Howe FA, Griffiths JR.

Biochim Biophys Acta. 1996 Oct 24;1291(2):143-8.

PMID:
8898875
16.

Diffusion through narrow pores: movement of ions, water and nonelectrolytes through track-etched PETP membranes.

Rostovtseva TK, Bashford CL, Alder GM, Hill GN, McGiffert C, Apel PY, Lowe G, Pasternak CA.

J Membr Biol. 1996 May;151(1):29-43.

PMID:
8661492
17.

Pore formation by S. aureus alpha-toxin in liposomes and planar lipid bilayers: effects of nonelectrolytes.

Bashford CL, Alder GM, Fulford LG, Korchev YE, Kovacs E, MacKinnon A, Pederzolli C, Pasternak CA.

J Membr Biol. 1996 Mar;150(1):37-45.

PMID:
8699478
18.

Membrane pores--from biology to track-etched membranes.

Bashford CL.

Biosci Rep. 1995 Dec;15(6):553-65. Review.

PMID:
9156584
19.

Low conductance states of a single ion channel are not 'closed'.

Korchev YE, Bashford CL, Alder GM, Kasianowicz JJ, Pasternak CA.

J Membr Biol. 1995 Oct;147(3):233-9.

PMID:
8558589
20.

Staphylococcus aureus alpha-toxin-induced pores: channel-like behavior in lipid bilayers and patch clamped cells.

Korchev YE, Alder GM, Bakhramov A, Bashford CL, Joomun BS, Sviderskaya EV, Usherwood PN, Pasternak CA.

J Membr Biol. 1995 Jan;143(2):143-51. Erratum in: J Membr Biol 1995 Mar;144(2):185.

PMID:
7537338
21.

Triton channels are sensitive to divalent cations and protons.

Rostovtseva TK, Bashford CL, Lev AA, Pasternak CA.

J Membr Biol. 1994 Jul;141(1):83-90.

PMID:
7525965
22.

Measurement of ion fluxes and pH gradients across cell membranes.

Bashford CL.

Methods Mol Biol. 1994;27:307-23. No abstract available.

PMID:
8298699
23.

Membrane permeabilization with bacterial toxins.

Bashford CL.

Methods Mol Biol. 1994;27:295-305. No abstract available.

PMID:
8298698
24.

Measurement of membrane fluidity and membrane fusion with fluorescent probes.

Bashford CL.

Methods Mol Biol. 1994;27:177-87. No abstract available.

PMID:
8298690
25.

Rapid switching of ion current in narrow pores: implications for biological ion channels.

Lev AA, Korchev YE, Rostovtseva TK, Bashford CL, Edmonds DT, Pasternak CA.

Proc Biol Sci. 1993 Jun 22;252(1335):187-92.

PMID:
7688899
26.

Membrane damage: common mechanisms of induction and prevention.

Pasternak CA, Alder GM, Bashford CL, Korchev YE, Pederzolli C, Rostovtseva TK.

FEMS Microbiol Immunol. 1992 Sep;5(1-3):83-92. Review.

PMID:
1384600
27.

Differential sensitivity of pneumolysin-induced channels to gating by divalent cations.

Korchev YE, Bashford CL, Pasternak CA.

J Membr Biol. 1992 May;127(3):195-203.

PMID:
1379644
28.

Characterization of non-lytic cytolysin-membrane intermediates.

Kuta AE, Bashford CL, Pasternak CA, Reynolds CW, Henkart PA.

Mol Immunol. 1991 Nov;28(11):1263-70.

PMID:
1961199
29.

Divalent cation-sensitive pores formed by natural and synthetic melittin and by Triton X-100.

Alder GM, Arnold WM, Bashford CL, Drake AF, Pasternak CA, Zimmermann U.

Biochim Biophys Acta. 1991 Jan 9;1061(1):111-20.

PMID:
1899800
30.

Heat shock proteins induce pores in membranes.

Alder GM, Austen BM, Bashford CL, Mehlert A, Pasternak CA.

Biosci Rep. 1990 Dec;10(6):509-18.

PMID:
1982226
31.

Action of diphtheria toxin does not depend on the induction of large, stable pores across biological membranes.

Alder GM, Bashford CL, Pasternak CA.

J Membr Biol. 1990 Jan;113(1):67-74.

PMID:
2304072
32.

Time resolved 3-dimensional recording of redox ratio during spreading depression in gerbil brain.

Haselgrove JC, Bashford CL, Barlow CH, Quistorff B, Chance B, Mayevsky A.

Brain Res. 1990 Jan 1;506(1):109-14.

PMID:
2302548
34.

Plasma membrane potential of lymphocytes from ataxia telangiectasia patients.

Ozer NK, Bashford CL, Carter ND, Pasternak CA.

Clin Biochem. 1989 Dec;22(6):469-73.

PMID:
2611994
35.

Mechanisms of attack and defence at the cell surface: the use of phospholipid bilayers as models for cell membrane.

Pasternak CA, Bashford CL, Menestrina G.

Biosci Rep. 1989 Aug;9(4):503-7. Review.

PMID:
2480163
36.
37.

Cell damage by cytolysin. Spontaneous recovery and reversible inhibition by divalent cations.

Bashford CL, Menestrina G, Henkart PA, Pasternak CA.

J Immunol. 1988 Dec 1;141(11):3965-74.

PMID:
2846697
38.

Ion modulation of membrane permeability: effect of cations on intact cells and on cells and phospholipid bilayers treated with pore-forming agents.

Bashford CL, Alder GM, Graham JM, Menestrina G, Pasternak CA.

J Membr Biol. 1988 Jul;103(1):79-94.

PMID:
2846846
39.

Membrane damage by hemolytic viruses, toxins, complement, and other cytotoxic agents. A common mechanism blocked by divalent cations.

Bashford CL, Alder GM, Menestrina G, Micklem KJ, Murphy JJ, Pasternak CA.

J Biol Chem. 1986 Jul 15;261(20):9300-8.

40.

Plasma membrane potential of neutrophils generated by the Na+ pump.

Bashford CL, Pasternak CA.

Biochim Biophys Acta. 1985 Jul 11;817(1):174-80.

PMID:
2408670
41.

Oxonol dyes as monitors of membrane potential: the effect of viruses and toxins on the plasma membrane potential of animal cells in monolayer culture and in suspension.

Bashford CL, Alder GM, Gray MA, Micklem KJ, Taylor CC, Turek PJ, Pasternak CA.

J Cell Physiol. 1985 Jun;123(3):326-36.

PMID:
3988810
42.

Sequential onset of permeability changes in mouse ascites cells induced by Sendai virus.

Bashford CL, Micklem KJ, Pasternak CA.

Biochim Biophys Acta. 1985 Apr 11;814(2):247-55.

PMID:
2983764
43.

Chemiluminescence in neutrophils and Lettré cells induced by myxoviruses.

Mehta S, Bashford CL, Knox P, Pasternak CA.

Biochem J. 1985 Apr 1;227(1):99-104.

44.

Cell damage by viruses, toxins and complement: common features of pore-formation and its inhibition by Ca2+.

Pasternak CA, Alder GM, Bashford CL, Buckley CD, Micklem KJ, Patel K.

Biochem Soc Symp. 1985;50:247-64. Review.

PMID:
3939403
45.

Generation of plasma membrane potential by the Na+-pump coupled to proton extrusion.

Bashford CL, Pasternak CA.

Eur Biophys J. 1985;12(4):229-35. Erratum in: Eur Biophys J 1986;14(1):65.

PMID:
2412812
46.

Common action of certain viruses, toxins, and activated complement: pore formation and its prevention by extracellular Ca2+.

Bashford CL, Alder GM, Patel K, Pasternak CA.

Biosci Rep. 1984 Sep;4(9):797-805.

PMID:
6095941
47.

Plasma membrane potential of Lettré cells does not depend on cation gradients but on pumps.

Bashford CL, Pasternak CA.

J Membr Biol. 1984;79(3):275-84.

PMID:
6471096
48.

A novel method for measuring intracellular pH and potassium concentration.

Bashford CL, Alder G, Micklem KJ, Pasternak CA.

Biosci Rep. 1983 Jul;3(7):631-42.

PMID:
6313090
49.

Optical measurements of oxygen delivery and consumption in gerbil cerebral cortex.

Bashford CL, Barlow CH, Chance B, Haselgrove J, Sorge J.

Am J Physiol. 1982 May;242(5):C265-71.

PMID:
7081423
50.

The measurement of membrane potential using optical indicators.

Bashford CL.

Biosci Rep. 1981 Mar;1(3):183-96. Review. No abstract available.

PMID:
7028151

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