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Items: 1 to 50 of 84

1.

Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis.

Frankowski KJ, Wang C, Patnaik S, Schoenen FJ, Southall N, Li D, Teper Y, Sun W, Kandela I, Hu D, Dextras C, Knotts Z, Bian Y, Norton J, Titus S, Lewandowska MA, Wen Y, Farley KI, Griner LM, Sultan J, Meng Z, Zhou M, Vilimas T, Powers AS, Kozlov S, Nagashima K, Quadri HS, Fang M, Long C, Khanolkar O, Chen W, Kang J, Huang H, Chow E, Goldberg E, Feldman C, Xi R, Kim HR, Sahagian G, Baserga SJ, Mazar A, Ferrer M, Zheng W, Shilatifard A, Aubé J, Rudloff U, Marugan JJ, Huang S.

Sci Transl Med. 2018 May 16;10(441). pii: eaap8307. doi: 10.1126/scitranslmed.aap8307.

PMID:
29769289
2.

Diverse Regulators of Human Ribosome Biogenesis Discovered by Changes in Nucleolar Number.

Farley-Barnes KI, McCann KL, Ogawa LM, Merkel J, Surovtseva YV, Baserga SJ.

Cell Rep. 2018 Feb 13;22(7):1923-1934. doi: 10.1016/j.celrep.2018.01.056.

3.

The SSU processome interactome in Saccharomyces cerevisiae reveals novel protein subcomplexes.

Vincent NG, Charette JM, Baserga SJ.

RNA. 2018 Jan;24(1):77-89. doi: 10.1261/rna.062927.117. Epub 2017 Oct 20.

PMID:
29054886
4.

Mutations in KDSR Cause Recessive Progressive Symmetric Erythrokeratoderma.

Boyden LM, Vincent NG, Zhou J, Hu R, Craiglow BG, Bayliss SJ, Rosman IS, Lucky AW, Diaz LA, Goldsmith LA, Paller AS, Lifton RP, Baserga SJ, Choate KA.

Am J Hum Genet. 2017 Jun 1;100(6):978-984. doi: 10.1016/j.ajhg.2017.05.003.

5.

Ribosomes Need Straight A's to Sleep.

Sondalle SB, Baserga SJ.

Cell. 2017 May 4;169(4):565-567. doi: 10.1016/j.cell.2017.04.019.

6.

The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma.

Tao T, Sondalle SB, Shi H, Zhu S, Perez-Atayde AR, Peng J, Baserga SJ, Look AT.

Oncogene. 2017 Jul 6;36(27):3852-3867. doi: 10.1038/onc.2016.527. Epub 2017 Mar 6.

7.

A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism.

Paolini NA, Attwood M, Sondalle SB, Vieira CMDS, van Adrichem AM, di Summa FM, O'Donohue MF, Gleizes PE, Rachuri S, Briggs JW, Fischer R, Ratcliffe PJ, Wlodarski MW, Houtkooper RH, von Lindern M, Kuijpers TW, Dinman JD, Baserga SJ, Cockman ME, MacInnes AW.

Am J Hum Genet. 2017 Mar 2;100(3):506-522. doi: 10.1016/j.ajhg.2017.01.034.

8.

Crosstalk between the nucleolus and the DNA damage response.

Ogawa LM, Baserga SJ.

Mol Biosyst. 2017 Feb 28;13(3):443-455. doi: 10.1039/c6mb00740f. Review.

9.

Expression of ribosomopathy genes during Xenopus tropicalis embryogenesis.

Robson A, Owens ND, Baserga SJ, Khokha MK, Griffin JN.

BMC Dev Biol. 2016 Oct 26;16(1):38.

10.

Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA.

Zhang J, McCann KL, Qiu C, Gonzalez LE, Baserga SJ, Hall TM.

Nat Commun. 2016 Oct 11;7:13085. doi: 10.1038/ncomms13085.

11.

Probing the mechanisms underlying human diseases in making ribosomes.

Farley KI, Baserga SJ.

Biochem Soc Trans. 2016 Aug 15;44(4):1035-44. doi: 10.1042/BST20160064. Review.

12.

Box C/D sRNA stem ends act as stabilizing anchors for box C/D di-sRNPs.

Yip WS, Shigematsu H, Taylor DW, Baserga SJ.

Nucleic Acids Res. 2016 Oct 14;44(18):8976-8989. Epub 2016 Jun 24.

13.

The Contributions of the Ribosome Biogenesis Protein Utp5/WDR43 to Craniofacial Development.

Sondalle SB, Baserga SJ, Yelick PC.

J Dent Res. 2016 Oct;95(11):1214-20. doi: 10.1177/0022034516651077. Epub 2016 May 24. Review.

14.

The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome.

McCann KL, Teramoto T, Zhang J, Tanaka Hall TM, Baserga SJ.

Elife. 2016 Apr 14;5. pii: e16381. doi: 10.7554/eLife.16381.

15.

A protein interaction map of the LSU processome.

McCann KL, Charette JM, Vincent NG, Baserga SJ.

Genes Dev. 2015 Apr 15;29(8):862-75. doi: 10.1101/gad.256370.114. Epub 2015 Apr 15.

16.

The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus.

Griffin JN, Sondalle SB, Del Viso F, Baserga SJ, Khokha MK.

PLoS Genet. 2015 Mar 10;11(3):e1005018. doi: 10.1371/journal.pgen.1005018. eCollection 2015 Mar.

17.

Determinants of mammalian nucleolar architecture.

Farley KI, Surovtseva Y, Merkel J, Baserga SJ.

Chromosoma. 2015 Sep;124(3):323-31. doi: 10.1007/s00412-015-0507-z. Epub 2015 Feb 12. Review.

18.

A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization.

Qiu C, McCann KL, Wine RN, Baserga SJ, Hall TM.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18554-9. doi: 10.1073/pnas.1407634112. Epub 2014 Dec 15.

19.

Driving nucleolar assembly.

McCann KL, Baserga SJ.

Genes Dev. 2014 Feb 1;28(3):211-3. doi: 10.1101/gad.237610.114.

20.

Human diseases of the SSU processome.

Sondalle SB, Baserga SJ.

Biochim Biophys Acta. 2014 Jun;1842(6):758-64. doi: 10.1016/j.bbadis.2013.11.004. Epub 2013 Nov 12. Review.

21.

Ribosome biogenesis in the yeast Saccharomyces cerevisiae.

Woolford JL Jr, Baserga SJ.

Genetics. 2013 Nov;195(3):643-81. doi: 10.1534/genetics.113.153197. Review.

22.

Genetics. Mysterious ribosomopathies.

McCann KL, Baserga SJ.

Science. 2013 Aug 23;341(6148):849-50. doi: 10.1126/science.1244156. No abstract available.

23.

Ribonucleoproteins in archaeal pre-rRNA processing and modification.

Yip WS, Vincent NG, Baserga SJ.

Archaea. 2013;2013:614735. doi: 10.1155/2013/614735. Epub 2013 Mar 10. Review.

24.

Long noncoding RNAs as sinks in Prader-Willi syndrome.

McCann KL, Baserga SJ.

Mol Cell. 2012 Oct 26;48(2):155-7. doi: 10.1016/j.molcel.2012.10.005.

25.

NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing.

Freed EF, Prieto JL, McCann KL, McStay B, Baserga SJ.

PLoS Genet. 2012;8(8):e1002892. doi: 10.1371/journal.pgen.1002892. Epub 2012 Aug 16.

26.

A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability.

Richardson LA, Reed BJ, Charette JM, Freed EF, Fredrickson EK, Locke MN, Baserga SJ, Gardner RG.

Cell Rep. 2012 Aug 30;2(2):372-85. doi: 10.1016/j.celrep.2012.07.009. Epub 2012 Aug 16.

27.

The box C/D sRNP dimeric architecture is conserved across domain Archaea.

Bower-Phipps KR, Taylor DW, Wang HW, Baserga SJ.

RNA. 2012 Aug;18(8):1527-40. doi: 10.1261/rna.033134.112. Epub 2012 Jun 29.

28.

In vivo approaches to dissecting the function of RNA helicases in eukaryotic ribosome assembly.

Rawling DC, Baserga SJ.

Methods Enzymol. 2012;511:289-321. doi: 10.1016/B978-0-12-396546-2.00014-0.

29.

Assembling a protein-protein interaction map of the SSU processome from existing datasets.

Lim YH, Charette JM, Baserga SJ.

PLoS One. 2011 Mar 10;6(3):e17701. doi: 10.1371/journal.pone.0017701.

30.

The initial U3 snoRNA:pre-rRNA base pairing interaction required for pre-18S rRNA folding revealed by in vivo chemical probing.

Dutca LM, Gallagher JE, Baserga SJ.

Nucleic Acids Res. 2011 Jul;39(12):5164-80. doi: 10.1093/nar/gkr044. Epub 2011 Feb 23.

31.

The small subunit processome in ribosome biogenesis—progress and prospects.

Phipps KR, Charette J, Baserga SJ.

Wiley Interdiscip Rev RNA. 2011 Jan-Feb;2(1):1-21. doi: 10.1002/wrna.57. Review.

32.

The DEAD-box RNA helicase-like Utp25 is an SSU processome component.

Charette JM, Baserga SJ.

RNA. 2010 Nov;16(11):2156-69. doi: 10.1261/rna.2359810. Epub 2010 Sep 30.

33.

Dissecting the role of conserved box C/D sRNA sequences in di-sRNP assembly and function.

Bleichert F, Baserga SJ.

Nucleic Acids Res. 2010 Dec;38(22):8295-305. doi: 10.1093/nar/gkq690. Epub 2010 Aug 6.

34.

Ribonucleoprotein multimers and their functions.

Bleichert F, Baserga SJ.

Crit Rev Biochem Mol Biol. 2010 Oct;45(5):331-50. doi: 10.3109/10409238.2010.496772. Review.

35.

The C-terminus of Utp4, mutated in childhood cirrhosis, is essential for ribosome biogenesis.

Freed EF, Baserga SJ.

Nucleic Acids Res. 2010 Aug;38(14):4798-806. doi: 10.1093/nar/gkq185. Epub 2010 Apr 12.

36.

When ribosomes go bad: diseases of ribosome biogenesis.

Freed EF, Bleichert F, Dutca LM, Baserga SJ.

Mol Biosyst. 2010 Mar;6(3):481-93. doi: 10.1039/b919670f. Epub 2010 Jan 11. Review.

37.

A dimeric structure for archaeal box C/D small ribonucleoproteins.

Bleichert F, Gagnon KT, Brown BA 2nd, Maxwell ES, Leschziner AE, Unger VM, Baserga SJ.

Science. 2009 Sep 11;325(5946):1384-7. doi: 10.1126/science.1176099.

38.

A structural model for the HAT domain of Utp6 incorporating bioinformatics and genetics.

Champion EA, Kundrat L, Regan L, Baserga SJ.

Protein Eng Des Sel. 2009 Jul;22(7):431-9. doi: 10.1093/protein/gzp022. Epub 2009 Jun 10.

39.

A direct interaction between the Utp6 half-a-tetratricopeptide repeat domain and a specific peptide in Utp21 is essential for efficient pre-rRNA processing.

Champion EA, Lane BH, Jackrel ME, Regan L, Baserga SJ.

Mol Cell Biol. 2008 Nov;28(21):6547-56. doi: 10.1128/MCB.00906-08. Epub 2008 Aug 25.

40.

The long unwinding road of RNA helicases.

Bleichert F, Baserga SJ.

Mol Cell. 2007 Aug 3;27(3):339-52. Review.

41.

Ribosome biogenesis is sensed at the Start cell cycle checkpoint.

Bernstein KA, Bleichert F, Bean JM, Cross FR, Baserga SJ.

Mol Biol Cell. 2007 Mar;18(3):953-64. Epub 2006 Dec 27.

42.

The nucleolar protein Esf2 interacts directly with the DExD/H box RNA helicase, Dbp8, to stimulate ATP hydrolysis.

Granneman S, Lin C, Champion EA, Nandineni MR, Zorca C, Baserga SJ.

Nucleic Acids Res. 2006 Jun 13;34(10):3189-99. Print 2006.

43.

The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation.

Bleichert F, Granneman S, Osheim YN, Beyer AL, Baserga SJ.

Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9464-9. Epub 2006 Jun 12.

44.

The coiled-coil domain of the Nop56/58 core protein is dispensable for sRNP assembly but is critical for archaeal box C/D sRNP-guided nucleotide methylation.

Zhang X, Champion EA, Tran EJ, Brown BA 2nd, Baserga SJ, Maxwell ES.

RNA. 2006 Jun;12(6):1092-103. Epub 2006 Apr 6.

45.

Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis.

Bernstein KA, Granneman S, Lee AV, Manickam S, Baserga SJ.

Mol Cell Biol. 2006 Feb;26(4):1195-208.

46.

Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis.

Granneman S, Bernstein KA, Bleichert F, Baserga SJ.

Mol Cell Biol. 2006 Feb;26(4):1183-94.

47.
48.
49.

Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae.

Osheim YN, French SL, Keck KM, Champion EA, Spasov K, Dragon F, Baserga SJ, Beyer AL.

Mol Cell. 2004 Dec 22;16(6):943-54.

50.

The small-subunit processome is a ribosome assembly intermediate.

Bernstein KA, Gallagher JE, Mitchell BM, Granneman S, Baserga SJ.

Eukaryot Cell. 2004 Dec;3(6):1619-26.

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