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Items: 10

1.

Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis.

Kim J, Eltorai AE, Jiang H, Liao F, Verghese PB, Kim J, Stewart FR, Basak JM, Holtzman DM.

J Exp Med. 2012 Nov 19;209(12):2149-56. doi: 10.1084/jem.20121274. Epub 2012 Nov 5.

2.

In vivo human apolipoprotein E isoform fractional turnover rates in the CNS.

Wildsmith KR, Basak JM, Patterson BW, Pyatkivskyy Y, Kim J, Yarasheski KE, Wang JX, Mawuenyega KG, Jiang H, Parsadanian M, Yoon H, Kasten T, Sigurdson WC, Xiong C, Goate A, Holtzman DM, Bateman RJ.

PLoS One. 2012;7(6):e38013. doi: 10.1371/journal.pone.0038013. Epub 2012 Jun 4.

3.

Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling.

Basak JM, Kim J, Pyatkivskyy Y, Wildsmith KR, Jiang H, Parsadanian M, Patterson BW, Bateman RJ, Holtzman DM.

Mol Neurodegener. 2012 Apr 18;7:14. doi: 10.1186/1750-1326-7-14.

4.

Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes.

Basak JM, Verghese PB, Yoon H, Kim J, Holtzman DM.

J Biol Chem. 2012 Apr 20;287(17):13959-71. doi: 10.1074/jbc.M111.288746. Epub 2012 Mar 1.

5.

Haploinsufficiency of human APOE reduces amyloid deposition in a mouse model of amyloid-β amyloidosis.

Kim J, Jiang H, Park S, Eltorai AE, Stewart FR, Yoon H, Basak JM, Finn MB, Holtzman DM.

J Neurosci. 2011 Dec 7;31(49):18007-12. doi: 10.1523/JNEUROSCI.3773-11.2011.

6.

Differential effects of ApoE isoforms on dendritic spines in vivo: linking an Alzheimer's disease risk factor with synaptic alterations.

Basak JM, Kim J.

J Neurosci. 2010 Mar 31;30(13):4526-7. doi: 10.1523/JNEUROSCI.0505-10.2010. No abstract available.

7.

Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.

Kim J, Castellano JM, Jiang H, Basak JM, Parsadanian M, Pham V, Mason SM, Paul SM, Holtzman DM.

Neuron. 2009 Dec 10;64(5):632-44. doi: 10.1016/j.neuron.2009.11.013.

8.

The role of apolipoprotein E in Alzheimer's disease.

Kim J, Basak JM, Holtzman DM.

Neuron. 2009 Aug 13;63(3):287-303. doi: 10.1016/j.neuron.2009.06.026. Review.

9.

The low density lipoprotein receptor-related protein 1 mediates uptake of amyloid beta peptides in an in vitro model of the blood-brain barrier cells.

Yamada K, Hashimoto T, Yabuki C, Nagae Y, Tachikawa M, Strickland DK, Liu Q, Bu G, Basak JM, Holtzman DM, Ohtsuki S, Terasaki T, Iwatsubo T.

J Biol Chem. 2008 Dec 12;283(50):34554-62. doi: 10.1074/jbc.M801487200. Epub 2008 Oct 21.

10.

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