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Items: 16

1.

Rapid Disruption of Genes Specifically in Livers of Mice Using Multiplex CRISPR/Cas9 Editing.

Pankowicz FP, Barzi M, Kim KH, Legras X, Martins CS, Wooton-Kee CR, Lagor WR, Marini JC, Elsea SH, Bissig-Choisat B, Moore DD, Bissig KD.

Gastroenterology. 2018 Dec;155(6):1967-1970.e6. doi: 10.1053/j.gastro.2018.08.037. Epub 2018 Aug 28.

PMID:
30170115
2.

P450-Humanized and Human Liver Chimeric Mouse Models for Studying Xenobiotic Metabolism and Toxicity.

Bissig KD, Han W, Barzi M, Kovalchuk N, Ding L, Fan X, Pankowicz FP, Zhang QY, Ding X.

Drug Metab Dispos. 2018 Nov;46(11):1734-1744. doi: 10.1124/dmd.118.083303. Epub 2018 Aug 9.

PMID:
30093418
3.

HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice.

Kruse RL, Shum T, Tashiro H, Barzi M, Yi Z, Whitten-Bauer C, Legras X, Bissig-Choisat B, Garaigorta U, Gottschalk S, Bissig KD.

Cytotherapy. 2018 May;20(5):697-705. doi: 10.1016/j.jcyt.2018.02.002. Epub 2018 Apr 6.

PMID:
29631939
4.

Erratum: A novel humanized mouse lacking murine p450 oxidoreductase for studying human drug metabolism.

Barzi M, Pankowicz FP, Zorman B, Liu X, Legras X, Yang D, Borowiak M, Bissig-Choisat B, Sumazin P, Li F, Bissig KD.

Nat Commun. 2017 Oct 17;8(1):984. doi: 10.1038/s41467-017-01314-9.

5.

In Situ Liver Expression of HBsAg/CD3-Bispecific Antibodies for HBV Immunotherapy.

Kruse RL, Shum T, Legras X, Barzi M, Pankowicz FP, Gottschalk S, Bissig KD.

Mol Ther Methods Clin Dev. 2017 Aug 31;7:32-41. doi: 10.1016/j.omtm.2017.08.006. eCollection 2017 Dec 15.

6.

A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism.

Barzi M, Pankowicz FP, Zorman B, Liu X, Legras X, Yang D, Borowiak M, Bissig-Choisat B, Sumazin P, Li F, Bissig KD.

Nat Commun. 2017 Jun 28;8(1):39. doi: 10.1038/s41467-017-00049-x. Erratum in: Nat Commun. 2017 Oct 17;8(1):984.

7.

Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia.

Pankowicz FP, Barzi M, Legras X, Hubert L, Mi T, Tomolonis JA, Ravishankar M, Sun Q, Yang D, Borowiak M, Sumazin P, Elsea SH, Bissig-Choisat B, Bissig KD.

Nat Commun. 2016 Aug 30;7:12642. doi: 10.1038/ncomms12642.

8.

Liver is liver and blood is blood, and finally the twain have met.

Bissig KD, Paust S, Barzi M.

J Hepatol. 2016 Aug;65(2):245-8. doi: 10.1016/j.jhep.2016.05.018. Epub 2016 May 21. No abstract available.

PMID:
27221221
9.

Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer.

Bissig-Choisat B, Kettlun-Leyton C, Legras XD, Zorman B, Barzi M, Chen LL, Amin MD, Huang YH, Pautler RG, Hampton OA, Prakash MM, Yang D, Borowiak M, Muzny D, Doddapaneni HV, Hu J, Shi Y, Gaber MW, Hicks MJ, Thompson PA, Lu Y, Mills GB, Finegold M, Goss JA, Parsons DW, Vasudevan SA, Sumazin P, López-Terrada D, Bissig KD.

J Hepatol. 2016 Aug;65(2):325-33. doi: 10.1016/j.jhep.2016.04.009. Epub 2016 Apr 23.

10.

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model.

Bissig-Choisat B, Wang L, Legras X, Saha PK, Chen L, Bell P, Pankowicz FP, Hill MC, Barzi M, Kettlun Leyton C, Leung HC, Kruse RL, Himes RW, Goss JA, Wilson JM, Chan L, Lagor WR, Bissig KD.

Nat Commun. 2015 Jun 17;6:7339. doi: 10.1038/ncomms8339.

11.
12.

Jagged2 controls the generation of motor neuron and oligodendrocyte progenitors in the ventral spinal cord.

Rabadán MA, Cayuso J, Le Dréau G, Cruz C, Barzi M, Pons S, Briscoe J, Martí E.

Cell Death Differ. 2012 Feb;19(2):209-19. doi: 10.1038/cdd.2011.84. Epub 2011 Jul 1.

13.

Sonic Hedgehog-induced proliferation requires specific Gα inhibitory proteins.

Barzi M, Kostrz D, Menendez A, Pons S.

J Biol Chem. 2011 Mar 11;286(10):8067-74. doi: 10.1074/jbc.M110.178772. Epub 2011 Jan 5.

14.

Sonic-hedgehog-mediated proliferation requires the localization of PKA to the cilium base.

Barzi M, Berenguer J, Menendez A, Alvarez-Rodriguez R, Pons S.

J Cell Sci. 2010 Jan 1;123(Pt 1):62-9. doi: 10.1242/jcs.060020.

15.

Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells.

Farina M, Campos F, Vendrell I, Berenguer J, Barzi M, Pons S, Suñol C.

Toxicol Sci. 2009 Dec;112(2):416-26. doi: 10.1093/toxsci/kfp219. Epub 2009 Sep 21.

PMID:
19770487
16.

Bone morphogenetic protein 2 opposes Shh-mediated proliferation in cerebellar granule cells through a TIEG-1-based regulation of Nmyc.

Alvarez-Rodríguez R, Barzi M, Berenguer J, Pons S.

J Biol Chem. 2007 Dec 21;282(51):37170-80. Epub 2007 Oct 19.

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