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Items: 28


Eviction from the sanctuary: Development of targeted therapy against cell adhesion molecules in acute lymphoblastic leukemia.

Barwe SP, Quagliano A, Gopalakrishnapillai A.

Semin Oncol. 2017 Apr;44(2):101-112. doi: 10.1053/j.seminoncol.2017.06.005. Epub 2017 Jul 11. Review.


Knockdown of sodium-calcium exchanger 1 induces epithelial-to-mesenchymal transition in kidney epithelial cells.

Balasubramaniam SL, Gopalakrishnapillai A, Petrelli NJ, Barwe SP.

J Biol Chem. 2017 Jul 7;292(27):11388-11399. doi: 10.1074/jbc.M116.752352. Epub 2017 May 26.


Epigenetic drug combination induces remission in mouse xenograft models of pediatric acute myeloid leukemia.

Gopalakrishnapillai A, Kolb EA, McCahan SM, Barwe SP.

Leuk Res. 2017 Jul;58:91-97. doi: 10.1016/j.leukres.2017.05.004. Epub 2017 May 5.


Epigenetic drug combination overcomes osteoblast-induced chemoprotection in pediatric acute lymphoid leukemia.

Quagliano A, Gopalakrishnapillai A, Barwe SP.

Leuk Res. 2017 May;56:36-43. doi: 10.1016/j.leukres.2017.01.030. Epub 2017 Jan 27.


Generation of Pediatric Leukemia Xenograft Models in NSG-B2m Mice: Comparison with NOD/SCID Mice.

Gopalakrishnapillai A, Kolb EA, Dhanan P, Bojja AS, Mason RW, Corao D, Barwe SP.

Front Oncol. 2016 Jun 27;6:162. doi: 10.3389/fonc.2016.00162. eCollection 2016.


Disruption of Annexin II /p11 Interaction Suppresses Leukemia Cell Binding, Homing and Engraftment, and Sensitizes the Leukemia Cells to Chemotherapy.

Gopalakrishnapillai A, Kolb EA, Dhanan P, Mason RW, Napper A, Barwe SP.

PLoS One. 2015 Oct 14;10(10):e0140564. doi: 10.1371/journal.pone.0140564. eCollection 2015.


Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity.

Lee SJ, Litan A, Li Z, Graves B, Lindsey S, Barwe SP, Langhans SA.

Mol Cancer. 2015 Aug 19;14:159. doi: 10.1186/s12943-015-0430-1.


Ion dependence of Na-K-ATPase-mediated epithelial cell adhesion and migration.

Balasubramaniam SL, Gopalakrishnapillai A, Barwe SP.

Am J Physiol Cell Physiol. 2015 Sep 15;309(6):C437-41. doi: 10.1152/ajpcell.00140.2015. Epub 2015 Jul 8. No abstract available.


Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression.

Huynh TP, Barwe SP, Lee SJ, McSpadden R, Franco OE, Hayward SW, Damoiseaux R, Grubbs SS, Petrelli NJ, Rajasekaran AK.

PLoS One. 2015 Apr 2;10(4):e0122442. doi: 10.1371/journal.pone.0122442. eCollection 2015.


Sodium-calcium exchanger 1 regulates epithelial cell migration via calcium-dependent extracellular signal-regulated kinase signaling.

Balasubramaniam SL, Gopalakrishnapillai A, Gangadharan V, Duncan RL, Barwe SP.

J Biol Chem. 2015 May 15;290(20):12463-73. doi: 10.1074/jbc.M114.629519. Epub 2015 Mar 13.


Inhibition of epidermal growth factor signaling by the cardiac glycoside ouabain in medulloblastoma.

Wolle D, Lee SJ, Li Z, Litan A, Barwe SP, Langhans SA.

Cancer Med. 2014 Oct;3(5):1146-58. doi: 10.1002/cam4.314. Epub 2014 Jul 23.


Gramicidin A induces metabolic dysfunction and energy depletion leading to cell death in renal cell carcinoma cells.

David JM, Owens TA, Barwe SP, Rajasekaran AK.

Mol Cancer Ther. 2013 Nov;12(11):2296-307. doi: 10.1158/1535-7163.MCT-13-0445. Epub 2013 Sep 4.


Regulation of Na,K-ATPase β1-subunit in TGF-β2-mediated epithelial-to-mesenchymal transition in human retinal pigmented epithelial cells.

Mony S, Lee SJ, Harper JF, Barwe SP, Langhans SA.

Exp Eye Res. 2013 Oct;115:113-22. doi: 10.1016/j.exer.2013.06.007. Epub 2013 Jun 28.


Dexamethasone-loaded block copolymer nanoparticles induce leukemia cell death and enhance therapeutic efficacy: a novel application in pediatric nanomedicine.

Krishnan V, Xu X, Barwe SP, Yang X, Czymmek K, Waldman SA, Mason RW, Jia X, Rajasekaran AK.

Mol Pharm. 2013 Jun 3;10(6):2199-210. doi: 10.1021/mp300350e. Epub 2012 Nov 29.


Na,K-ATPase β-subunit cis homo-oligomerization is necessary for epithelial lumen formation in mammalian cells.

Barwe SP, Skay A, McSpadden R, Huynh TP, Langhans SA, Inge LJ, Rajasekaran AK.

J Cell Sci. 2012 Dec 1;125(Pt 23):5711-20. doi: 10.1242/jcs.108795. Epub 2012 Oct 17.


Soluble E-cadherin promotes cell survival by activating epidermal growth factor receptor.

Inge LJ, Barwe SP, D'Ambrosio J, Gopal J, Lu K, Ryazantsev S, Rajasekaran SA, Rajasekaran AK.

Exp Cell Res. 2011 Apr 1;317(6):838-48. doi: 10.1016/j.yexcr.2010.12.025. Epub 2011 Jan 4.


Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit.

Barwe SP, Jordan MC, Skay A, Inge L, Rajasekaran SA, Wolle D, Johnson CL, Neco P, Fang K, Rozengurt N, Goldhaber JI, Roos KP, Rajasekaran AK.

J Mol Cell Cardiol. 2009 Oct;47(4):552-60. doi: 10.1016/j.yjmcc.2009.07.018. Epub 2009 Aug 15.


Expression of Na,K-ATPase-beta(1) subunit increases uptake and sensitizes carcinoma cells to oxaliplatin.

Tummala R, Wolle D, Barwe SP, Sampson VB, Rajasekaran AK, Pendyala L.

Cancer Chemother Pharmacol. 2009 Nov;64(6):1187-94. doi: 10.1007/s00280-009-0985-x. Epub 2009 Mar 26.


alpha-Catenin overrides Src-dependent activation of beta-catenin oncogenic signaling.

Inge LJ, Rajasekaran SA, Wolle D, Barwe SP, Ryazantsev S, Ewing CM, Isaacs WB, Rajasekaran AK.

Mol Cancer Ther. 2008 Jun;7(6):1386-97. doi: 10.1158/1535-7163.MCT-07-2029.


Interaction of prostate specific membrane antigen with clathrin and the adaptor protein complex-2.

Goodman OB Jr, Barwe SP, Ritter B, McPherson PS, Vasko AJ, Keen JH, Nanus DM, Bander NH, Rajasekaran AK.

Int J Oncol. 2007 Nov;31(5):1199-203.


Preferential association of prostate cancer cells expressing prostate specific membrane antigen to bone marrow matrix.

Barwe SP, Maul RS, Christiansen JJ, Anilkumar G, Cooper CR, Kohn DB, Rajasekaran AK.

Int J Oncol. 2007 Apr;30(4):899-904.


Janus model of the Na,K-ATPase beta-subunit transmembrane domain: distinct faces mediate alpha/beta assembly and beta-beta homo-oligomerization.

Barwe SP, Kim S, Rajasekaran SA, Bowie JU, Rajasekaran AK.

J Mol Biol. 2007 Jan 19;365(3):706-14. Epub 2006 Oct 31.


Na-K-ATPase regulates tight junction permeability through occludin phosphorylation in pancreatic epithelial cells.

Rajasekaran SA, Barwe SP, Gopal J, Ryazantsev S, Schneeberger EE, Rajasekaran AK.

Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G124-33. Epub 2006 Sep 7.


Association of prostate-specific membrane antigen with caveolin-1 and its caveolae-dependent internalization in microvascular endothelial cells: implications for targeting to tumor vasculature.

Anilkumar G, Barwe SP, Christiansen JJ, Rajasekaran SA, Kohn DB, Rajasekaran AK.

Microvasc Res. 2006 Jul-Sep;72(1-2):54-61. Epub 2006 May 19.


Multiple functions of Na,K-ATPase in epithelial cells.

Rajasekaran SA, Barwe SP, Rajasekaran AK.

Semin Nephrol. 2005 Sep;25(5):328-34. Review.


Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility.

Barwe SP, Anilkumar G, Moon SY, Zheng Y, Whitelegge JP, Rajasekaran SA, Rajasekaran AK.

Mol Biol Cell. 2005 Mar;16(3):1082-94. Epub 2004 Dec 22.


HLA class I signal transduction is dependent on Rho GTPase and ROK.

Lepin EJ, Jin YP, Barwe SP, Rozengurt E, Reed EF.

Biochem Biophys Res Commun. 2004 Oct 8;323(1):213-7.


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