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Items: 1 to 50 of 100

1.

Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment by bioluminescence imaging.

Zhou C, Cai H, Baruch A, Lewin-Koh N, Yang M, Guo F, Xu D, Deng R, Hazenbos W, Kamath AV.

PLoS One. 2019 Oct 29;14(10):e0224096. doi: 10.1371/journal.pone.0224096. eCollection 2019.

2.

Prognostic Power of Pathogen Cell-Free DNA in Staphylococcus aureus Bacteremia.

Guimaraes AO, Gutierrez J, Maskarinec SA, Cao Y, Hong K, Ruffin F, Carrasco-Triguero M, Peck MC, Fowler VG, Baruch A, Rosenberger CM.

Open Forum Infect Dis. 2019 Mar 15;6(4):ofz126. doi: 10.1093/ofid/ofz126. eCollection 2019 Apr.

3.

Sustained Circulating Bacterial Deoxyribonucleic Acid Is Associated With Complicated Staphylococcus aureus Bacteremia.

Gutierrez J, Guimaraes AO, Lewin-Koh N, Berhanu A, Xu M, Cao Y, Kim J, Yan D, Chang JK, Dinoso JB, Koss CA, Clemenzi-Allen A, Chambers HF, Peck MC, Baruch A, Rosenberger CM.

Open Forum Infect Dis. 2019 Feb 26;6(4):ofz090. doi: 10.1093/ofid/ofz090. eCollection 2019 Apr.

4.

Long term metabolic and renal outcomes of kidney donors compared to controls with excellent kidney function.

Grupper A, Angel Y, Baruch A, Schwartz IF, Schwartz D, Nakache R, Goykhman Y, Katz P, Nachmany I, Lubezky N, Weinstein T, Shashar M, Ben-Bassat OK, Berliner S, Rogowski O, Zeltser D, Shapira I, Shenhar-Tsarfaty S.

BMC Nephrol. 2019 Jan 31;20(1):30. doi: 10.1186/s12882-019-1214-4.

5.

Ultrapure Filter does not Confer Short-Term Benefits over Two Reverse Osmosis Systems in Chronic Hemodialysis Patients.

Grupper A, Shashar M, Weinstein T, Kliuk Ben Bassat O, Levy S, Schwartz IF, Angel A, Baruch A, Grupper A, Chernin G, Schwartz D.

Isr Med Assoc J. 2019 Jan;21(1):5-9.

6.

Amygdalar activity predicts future incident diabetes independently of adiposity.

Osborne MT, Ishai A, Hammad B, Tung B, Wang Y, Baruch A, Fayad ZA, Giles JT, Lo J, Shin LM, Grinspoon SK, Koenen KC, Pitman RK, Tawakol A.

Psychoneuroendocrinology. 2019 Feb;100:32-40. doi: 10.1016/j.psyneuen.2018.09.024. Epub 2018 Sep 22.

PMID:
30273797
7.

A Prognostic Model of Persistent Bacteremia and Mortality in Complicated Staphylococcus aureus Bloodstream Infection.

Guimaraes AO, Cao Y, Hong K, Mayba O, Peck MC, Gutierrez J, Ruffin F, Carrasco-Triguero M, Dinoso JB, Clemenzi-Allen A, Koss CA, Maskarinec SA, Chambers HF, Fowler VG, Baruch A, Rosenberger CM.

Clin Infect Dis. 2019 Apr 24;68(9):1502-1511. doi: 10.1093/cid/ciy739.

8.

Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths.

Ruuth M, Nguyen SD, Vihervaara T, Hilvo M, Laajala TD, Kondadi PK, Gisterå A, Lähteenmäki H, Kittilä T, Huusko J, Uusitupa M, Schwab U, Savolainen MJ, Sinisalo J, Lokki ML, Nieminen MS, Jula A, Perola M, Ylä-Herttula S, Rudel L, Öörni A, Baumann M, Baruch A, Laaksonen R, Ketelhuth DFJ, Aittokallio T, Jauhiainen M, Käkelä R, Borén J, Williams KJ, Kovanen PT, Öörni K.

Eur Heart J. 2018 Jul 14;39(27):2562-2573. doi: 10.1093/eurheartj/ehy319.

9.

Corrigendum to 'Effects of RG7652, a Monoclonal Antibody Against PCSK9, on Low-Density Lipoprotein Cholesterol (LDL-C), LDL-C Subfractions, and Inflammatory Biomarkers in Patients at High Risk of or with Established Coronary Heart Disease (From the Phase 2 EQUATOR Study)' The American Journal of Cardiology 119 (2017) 1576-1583.

Baruch A, Mosesova S, Davis JD, Budha N, Vilimovskij A, Kahn R, Peng K, Cowan KJ, Harris LP, Gelzleichter T, Lehrer J, Davis JC Jr, Tingley WG.

Am J Cardiol. 2018 Aug 1;122(3):527. doi: 10.1016/j.amjcard.2018.01.010. Epub 2018 Feb 12. No abstract available.

PMID:
29448977
10.

PCSK9 inhibition alters the lipidome of plasma and lipoprotein fractions.

Hilvo M, Simolin H, Metso J, Ruuth M, Öörni K, Jauhiainen M, Laaksonen R, Baruch A.

Atherosclerosis. 2018 Feb;269:159-165. doi: 10.1016/j.atherosclerosis.2018.01.004. Epub 2018 Jan 12.

PMID:
29366988
11.

Preclinical pharmacokinetic characterization of an adipose tissue-targeting monoclonal antibody in obese and non-obese animals.

Rajan S, Mandikian D, Baruch A, Gelzleichter TR, Stevens D, Sonoda J, Cowan K, Boswell CA, Stefanich E.

MAbs. 2017 Nov/Dec;9(8):1379-1388. doi: 10.1080/19420862.2017.1373923. Epub 2017 Sep 12.

12.

Opioid Prescribing Patterns by Obstetrics and Gynecology Residents in the United States.

Baruch AD, Morgan DM, Dalton VK, Swenson C.

Subst Use Misuse. 2018 Jan 2;53(1):70-76. doi: 10.1080/10826084.2017.1323928. Epub 2017 Sep 1.

PMID:
28862884
13.

FGF21-receptor agonists: an emerging therapeutic class for obesity-related diseases.

Sonoda J, Chen MZ, Baruch A.

Horm Mol Biol Clin Investig. 2017 May 19;30(2). pii: /j/hmbci.2017.30.issue-2/hmbci-2017-0002/hmbci-2017-0002.xml. doi: 10.1515/hmbci-2017-0002. Review.

PMID:
28525362
14.

Effects of RG7652, a Monoclonal Antibody Against PCSK9, on LDL-C, LDL-C Subfractions, and Inflammatory Biomarkers in Patients at High Risk of or With Established Coronary Heart Disease (from the Phase 2 EQUATOR Study).

Baruch A, Mosesova S, Davis JD, Budha N, Vilimovskij A, Kahn R, Peng K, Cowan KJ, Harris LP, Gelzleichter T, Lehrer J, Davis JC Jr, Tingley WG.

Am J Cardiol. 2017 May 15;119(10):1576-1583. doi: 10.1016/j.amjcard.2017.02.020. Epub 2017 Mar 1. Erratum in: Am J Cardiol. 2018 Feb 12;:.

PMID:
28343601
15.

A phase 1 study to evaluate the safety and LDL cholesterol-lowering effects of RG7652, a fully human monoclonal antibody against proprotein convertase subtilisin/kexin type 9.

Baruch A, Luca D, Kahn RS, Cowan KJ, Leabman M, Budha NR, Chiu CPC, Wu Y, Kirchhofer D, Peterson A, Davis JC Jr, Tingley WG.

Clin Cardiol. 2017 Jul;40(7):503-511. doi: 10.1002/clc.22687. Epub 2017 Mar 22.

16.

Pharmacokinetics and pharmacodynamics of DSTA4637A: A novel THIOMAB™ antibody antibiotic conjugate against Staphylococcus aureus in mice.

Zhou C, Lehar S, Gutierrez J, Rosenberger CM, Ljumanovic N, Dinoso J, Koppada N, Hong K, Baruch A, Carrasco-Triguero M, Saad O, Mariathasan S, Kamath AV.

MAbs. 2016 Nov/Dec;8(8):1612-1619. Epub 2016 Sep 21.

17.

Micro and Macroscale Drivers of Nutrient Concentrations in Urban Streams in South, Central and North America.

Loiselle SA, Gasparini Fernandes Cunha D, Shupe S, Valiente E, Rocha L, Heasley E, Belmont PP, Baruch A.

PLoS One. 2016 Sep 23;11(9):e0162684. doi: 10.1371/journal.pone.0162684. eCollection 2016.

18.

Characterization of IL-17AA and IL-17FF in rheumatoid arthritis and multiple sclerosis.

Schofield C, Fischer SK, Townsend MJ, Mosesova S, Peng K, Setiadi AF, Song A, Baruch A.

Bioanalysis. 2016 Nov;8(22):2317-2327. Epub 2016 Sep 13.

19.

Treatment with a human recombinant monoclonal IgG antibody against oxidized LDL in atherosclerosis-prone pigs reduces cathepsin S in coronary lesions.

Poulsen CB, Al-Mashhadi AL, von Wachenfeldt K, Bentzon JF, Nielsen LB, Al-Mashhadi RH, Thygesen J, Tolbod L, Larsen JR, Frøkiær J, Tawakol A, Vucic E, Fredrickson J, Baruch A, Frendéus B, Robertson AK, Moestrup SK, Drouet L, Falk E.

Int J Cardiol. 2016 Jul 15;215:506-15. doi: 10.1016/j.ijcard.2016.03.222. Epub 2016 Apr 2.

PMID:
27135822
20.

Critical Cysteine Residues in Both the Calcium-Sensing Receptor and the Allosteric Activator AMG 416 Underlie the Mechanism of Action.

Alexander ST, Hunter T, Walter S, Dong J, Maclean D, Baruch A, Subramanian R, Tomlinson JE.

Mol Pharmacol. 2015 Nov;88(5):853-65. doi: 10.1124/mol.115.098392. Epub 2015 Aug 19.

PMID:
26290606
21.

Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex.

Kolumam G, Chen MZ, Tong R, Zavala-Solorio J, Kates L, van Bruggen N, Ross J, Wyatt SK, Gandham VD, Carano RA, Dunshee DR, Wu AL, Haley B, Anderson K, Warming S, Rairdan XY, Lewin-Koh N, Zhang Y, Gutierrez J, Baruch A, Gelzleichter TR, Stevens D, Rajan S, Bainbridge TW, Vernes JM, Meng YG, Ziai J, Soriano RH, Brauer MJ, Chen Y, Stawicki S, Kim HS, Comps-Agrar L, Luis E, Spiess C, Wu Y, Ernst JA, McGuinness OP, Peterson AS, Sonoda J.

EBioMedicine. 2015 May 30;2(7):730-43. doi: 10.1016/j.ebiom.2015.05.028. eCollection 2015 Jul.

22.

Retroperitoneal hemorrhage presenting as a vaginal hematoma after a spontaneous vaginal delivery.

Baruch A, Stentz NC, Wallett SM.

Int J Gynaecol Obstet. 2015 Aug;130(2):201-2. doi: 10.1016/j.ijgo.2015.02.029. Epub 2015 Apr 24. No abstract available.

23.

Modeling and Simulation to Support Phase 2 Dose Selection for RG7652, a Fully Human Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9.

Budha NR, Leabman M, Jin JY, Wada DR, Baruch A, Peng K, Tingley WG, Davis JD.

AAPS J. 2015 Jul;17(4):881-90. doi: 10.1208/s12248-015-9750-8. Epub 2015 Mar 31.

24.

Splenic metabolic activity predicts risk of future cardiovascular events: demonstration of a cardiosplenic axis in humans.

Emami H, Singh P, MacNabb M, Vucic E, Lavender Z, Rudd JH, Fayad ZA, Lehrer-Graiwer J, Korsgren M, Figueroa AL, Fredrickson J, Rubin B, Hoffmann U, Truong QA, Min JK, Baruch A, Nasir K, Nahrendorf M, Tawakol A.

JACC Cardiovasc Imaging. 2015 Feb;8(2):121-30. doi: 10.1016/j.jcmg.2014.10.009. Epub 2015 Jan 7.

25.

FDG-PET imaging for oxidized LDL in stable atherosclerotic disease: a phase II study of safety, tolerability, and anti-inflammatory activity.

Lehrer-Graiwer J, Singh P, Abdelbaky A, Vucic E, Korsgren M, Baruch A, Fredrickson J, van Bruggen N, Tang MT, Frendeus B, Rudd JHF, Hsieh F, Ballantyne CM, Ghoshhajra B, Rosenson RS, Koren M, Roth EM, Duprez DA, Fayad ZA, Tawakol AA.

JACC Cardiovasc Imaging. 2015 Apr;8(4):493-494. doi: 10.1016/j.jcmg.2014.06.021. Epub 2014 Nov 12. No abstract available.

26.

A Mechanistic Systems Pharmacology Model for Prediction of LDL Cholesterol Lowering by PCSK9 Antagonism in Human Dyslipidemic Populations.

Gadkar K, Budha N, Baruch A, Davis JD, Fielder P, Ramanujan S.

CPT Pharmacometrics Syst Pharmacol. 2014 Nov 26;3:e149. doi: 10.1038/psp.2014.47.

27.

Comparison of AMG 416 and cinacalcet in rodent models of uremia.

Walter S, Baruch A, Alexander ST, Janes J, Sho E, Dong J, Yin Q, Maclean D, Mendel DB, Karim F, Johnson RM.

BMC Nephrol. 2014 May 19;15:81. doi: 10.1186/1471-2369-15-81.

28.

Combined administration of RG7652, a recombinant human monoclonal antibody against PCSK9, and atorvastatin does not result in reduction of immune function.

Gelzleichter TR, Halpern W, Erwin R, Baruch A, Leabman M, Forrest AS, Satterwhite CM, Peng K, Chilton J, Stevens D.

Toxicol Sci. 2014 Aug 1;140(2):470-80. doi: 10.1093/toxsci/kfu093. Epub 2014 May 20.

PMID:
24848798
29.

[Medical students' views on the use of virtual patients for teaching and assessment of clinical knowledge and reasoning].

Oliven A, Nave R, Hasson-Gilad DR, Baruch A.

Harefuah. 2013 May;152(5):257-61, 310. Hebrew.

PMID:
23885447
30.

Pharmacology of AMG 416 (Velcalcetide), a novel peptide agonist of the calcium-sensing receptor, for the treatment of secondary hyperparathyroidism in hemodialysis patients.

Walter S, Baruch A, Dong J, Tomlinson JE, Alexander ST, Janes J, Hunter T, Yin Q, Maclean D, Bell G, Mendel DB, Johnson RM, Karim F.

J Pharmacol Exp Ther. 2013 Aug;346(2):229-40. doi: 10.1124/jpet.113.204834. Epub 2013 May 14.

PMID:
23674604
31.

Anti-inflammatory strategies for plaque stabilization after acute coronary syndromes.

Baruch A, van Bruggen N, Kim JB, Lehrer-Graiwer JE.

Curr Atheroscler Rep. 2013 Jun;15(6):327. doi: 10.1007/s11883-013-0327-7. Review. Erratum in: Curr Atheroscler Rep. 2013 Dec;15(12):374.

PMID:
23636864
32.
33.

Linezolid in methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a randomized, controlled study.

Wunderink RG, Niederman MS, Kollef MH, Shorr AF, Kunkel MJ, Baruch A, McGee WT, Reisman A, Chastre J.

Clin Infect Dis. 2012 Mar 1;54(5):621-9. doi: 10.1093/cid/cir895. Epub 2012 Jan 12.

PMID:
22247123
34.

Comparison of pharmacokinetics and safety of voriconazole intravenous-to-oral switch in immunocompromised children and healthy adults.

Driscoll TA, Yu LC, Frangoul H, Krance RA, Nemecek E, Blumer J, Arrieta A, Graham ML, Bradfield SM, Baruch A, Liu P.

Antimicrob Agents Chemother. 2011 Dec;55(12):5770-9. doi: 10.1128/AAC.00531-11. Epub 2011 Oct 3.

35.

Comparison of pharmacokinetics and safety of voriconazole intravenous-to-oral switch in immunocompromised adolescents and healthy adults.

Driscoll TA, Frangoul H, Nemecek ER, Murphey DK, Yu LC, Blumer J, Krance RA, Baruch A, Liu P.

Antimicrob Agents Chemother. 2011 Dec;55(12):5780-9. doi: 10.1128/AAC.05010-11. Epub 2011 Sep 12.

36.

Efficacy of p16 and ProExC immunostaining in the detection of high-grade cervical intraepithelial neoplasia and cervical carcinoma.

Guo M, Baruch AC, Silva EG, Jan YJ, Lin E, Sneige N, Deavers MT.

Am J Clin Pathol. 2011 Feb;135(2):212-20. doi: 10.1309/AJCP1LLX8QMDXHHO.

PMID:
21228361
37.

Efficacy and safety of linezolid versus vancomycin for the treatment of complicated skin and soft-tissue infections proven to be caused by methicillin-resistant Staphylococcus aureus.

Itani KM, Dryden MS, Bhattacharyya H, Kunkel MJ, Baruch AM, Weigelt JA.

Am J Surg. 2010 Jun;199(6):804-16. doi: 10.1016/j.amjsurg.2009.08.045. Epub 2010 Mar 15.

PMID:
20227056
38.

Domesticated dogs' (Canis familiaris) use of the solidity principle.

Kundey SM, De Los Reyes A, Taglang C, Baruch A, German R.

Anim Cogn. 2010 May;13(3):497-505. doi: 10.1007/s10071-009-0300-6. Epub 2009 Dec 20.

PMID:
20091202
39.

Proteinases as hormones: targets and mechanisms for proteolytic signaling.

Hansen KK, Oikonomopoulou K, Baruch A, Ramachandran R, Beck P, Diamandis EP, Hollenberg MD.

Biol Chem. 2008 Aug;389(8):971-82. doi: 10.1515/BC.2008.120. Review.

PMID:
18979623
40.

Immunofluorometric activity-based probe analysis of active KLK6 in biological fluids.

Oikonomopoulou K, Hansen KK, Baruch A, Hollenberg MD, Diamandis EP.

Biol Chem. 2008 Jun;389(6):747-56. doi: 10.1515/BC.2008.086.

PMID:
18627291
41.

Applications for chemical probes of proteolytic activity.

Bogyo M, Baruch A, Jeffery DA, Greenbaum D, Borodovsky A, Ovaa H, Kessler B.

Curr Protoc Protein Sci. 2004 Sep;Chapter 21:Unit 21.17. doi: 10.1002/0471140864.ps2117s36.

PMID:
18429259
42.

Immunocytochemical study of the expression of mesothelin in fine-needle aspiration biopsy specimens of pancreatic adenocarcinoma.

Baruch AC, Wang H, Staerkel GA, Evans DB, Hwang RF, Krishnamurthy S.

Diagn Cytopathol. 2007 Mar;35(3):143-7.

PMID:
17304533
43.

Thumb flexor pulley reconstruction with distally based extensor pollicis brevis tendon: Technique and biomechanical analysis.

Slesarenko YA, Baruch A, Mallo GC, Serra-Hsu F.

Tech Hand Up Extrem Surg. 2006 Jun;10(2):114-7. No abstract available.

PMID:
16783216
44.

Development of activity-based probes for trypsin-family serine proteases.

Pan Z, Jeffery DA, Chehade K, Beltman J, Clark JM, Grothaus P, Bogyo M, Baruch A.

Bioorg Med Chem Lett. 2006 Jun 1;16(11):2882-5. Epub 2006 Mar 22.

PMID:
16554154
45.

Safety and pharmacokinetics of coadministered voriconazole and anidulafungin.

Dowell JA, Schranz J, Baruch A, Foster G.

J Clin Pharmacol. 2005 Dec;45(12):1373-82.

PMID:
16291712
46.

New developments in the staging of melanoma.

Baruch AC, Shi J, Feng Y, Nelson MA.

Cancer Invest. 2005;23(6):561-7. Review.

PMID:
16203664
47.

A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis.

Hansen KK, Sherman PM, Cellars L, Andrade-Gordon P, Pan Z, Baruch A, Wallace JL, Hollenberg MD, Vergnolle N.

Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8363-8. Epub 2005 May 26.

48.

Electrochemical detection of xenoestrogenic and antiestrogenic compounds using a yeast two-hybrid-17-beta-estradiol system.

Schwartz-Mittelman A, Baruch A, Neufeld T, Buchner V, Rishpon J.

Bioelectrochemistry. 2005 Feb;65(2):149-56. Epub 2004 Dec 28.

PMID:
15713566
49.

Pulmonary adenocarcinomas associated with rheumatoid nodules: a case report and review of the literature.

Baruch AC, Steinbronn K, Sobonya R.

Arch Pathol Lab Med. 2005 Jan;129(1):104-6.

PMID:
15628888
50.

A novel protein derived from the MUC1 gene by alternative splicing and frameshifting.

Levitin F, Baruch A, Weiss M, Stiegman K, Hartmann ML, Yoeli-Lerner M, Ziv R, Zrihan-Licht S, Shina S, Gat A, Lifschitz B, Simha M, Stadler Y, Cholostoy A, Gil B, Greaves D, Keydar I, Zaretsky J, Smorodinsky N, Wreschner DH.

J Biol Chem. 2005 Mar 18;280(11):10655-63. Epub 2004 Dec 28.

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