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Items: 1 to 50 of 113

1.

Mice deficient in the lysosomal enzyme palmitoyl-protein thioesterase 1 (PPT1) display a complex retinal phenotype.

Atiskova Y, Bartsch S, Danyukova T, Becker E, Hagel C, Storch S, Bartsch U.

Sci Rep. 2019 Oct 2;9(1):14185. doi: 10.1038/s41598-019-50726-8.

2.

Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis.

Marques ARA, Di Spiezio A, Thießen N, Schmidt L, Grötzinger J, Lüllmann-Rauch R, Damme M, Storck SE, Pietrzik CU, Fogh J, Bär J, Mikhaylova M, Glatzel M, Bassal M, Bartsch U, Saftig P.

Autophagy. 2019 Jul 16:1-15. doi: 10.1080/15548627.2019.1637200. [Epub ahead of print]

PMID:
31282275
3.

Sleep problems and associations with psychopathology and cognition in young people with 22q11.2 deletion syndrome (22q11.2DS).

Moulding HA, Bartsch U, Hall J, Jones MW, Linden DE, Owen MJ, van den Bree MBM.

Psychol Med. 2019 May 30:1-12. doi: 10.1017/S0033291719001119. [Epub ahead of print]

PMID:
31144615
4.

Epilepsy and seizures in young people with 22q11.2 deletion syndrome: Prevalence and links with other neurodevelopmental disorders.

Eaton CB, Thomas RH, Hamandi K, Payne GC, Kerr MP, Linden DEJ, Owen MJ, Cunningham AC, Bartsch U, Struik SS, van den Bree MBM.

Epilepsia. 2019 May;60(5):818-829. doi: 10.1111/epi.14722. Epub 2019 Apr 11.

5.

Current and Emerging Treatment Strategies for Neuronal Ceroid Lipofuscinoses.

Kohlschütter A, Schulz A, Bartsch U, Storch S.

CNS Drugs. 2019 Apr;33(4):315-325. doi: 10.1007/s40263-019-00620-8.

6.

Pronounced synergistic neuroprotective effect of GDNF and CNTF on axotomized retinal ganglion cells in the adult mouse.

Flachsbarth K, Jankowiak W, Kruszewski K, Helbing S, Bartsch S, Bartsch U.

Exp Eye Res. 2018 Nov;176:258-265. doi: 10.1016/j.exer.2018.09.006. Epub 2018 Sep 17.

PMID:
30237104
7.

Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood.

Stanelle-Bertram S, Walendy-Gnirß K, Speiseder T, Thiele S, Asante IA, Dreier C, Kouassi NM, Preuß A, Pilnitz-Stolze G, Müller U, Thanisch S, Richter M, Scharrenberg R, Kraus V, Dörk R, Schau L, Herder V, Gerhauser I, Pfankuche VM, Käufer C, Waltl I, Moraes T, Sellau J, Hoenow S, Schmidt-Chanasit J, Jansen S, Schattling B, Ittrich H, Bartsch U, Renné T, Bartenschlager R, Arck P, Cadar D, Friese MA, Vapalahti O, Lotter H, Benites S, Rolling L, Gabriel M, Baumgärtner W, Morellini F, Hölter SM, Amarie O, Fuchs H, Hrabe de Angelis M, Löscher W, Calderon de Anda F, Gabriel G.

Nat Microbiol. 2018 Oct;3(10):1161-1174. doi: 10.1038/s41564-018-0236-1. Epub 2018 Sep 10.

PMID:
30202017
8.

Coordination of Slow Waves With Sleep Spindles Predicts Sleep-Dependent Memory Consolidation in Schizophrenia.

Demanuele C, Bartsch U, Baran B, Khan S, Vangel MG, Cox R, Hämäläinen M, Jones MW, Stickgold R, Manoach DS.

Sleep. 2017 Jan 1;40(1). doi: 10.1093/sleep/zsw013.

9.

Retinal Degeneration in Mice Deficient in the Lysosomal Membrane Protein CLN7.

Jankowiak W, Brandenstein L, Dulz S, Hagel C, Storch S, Bartsch U.

Invest Ophthalmol Vis Sci. 2016 Sep 1;57(11):4989-4998. doi: 10.1167/iovs.16-20158.

PMID:
27654426
10.

Degeneration of Photoreceptor Cells in Arylsulfatase G-Deficient Mice.

Kruszewski K, Lüllmann-Rauch R, Dierks T, Bartsch U, Damme M.

Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1120-31. doi: 10.1167/iovs.15-17645.

PMID:
26975023
11.

Genetics, sleep and memory: a recall-by-genotype study of ZNF804A variants and sleep neurophysiology.

Hellmich C, Durant C, Jones MW, Timpson NJ, Bartsch U, Corbin LJ.

BMC Med Genet. 2015 Oct 24;16:96. doi: 10.1186/s12881-015-0244-4.

12.

Novel morphological macular findings in juvenile CLN3 disease.

Dulz S, Wagenfeld L, Nickel M, Richard G, Schwartz R, Bartsch U, Kohlschütter A, Schulz A.

Br J Ophthalmol. 2016 Jun;100(6):824-8. doi: 10.1136/bjophthalmol-2015-307320. Epub 2015 Oct 20.

PMID:
26486417
13.

Sustained Neural Stem Cell-Based Intraocular Delivery of CNTF Attenuates Photoreceptor Loss in the nclf Mouse Model of Neuronal Ceroid Lipofuscinosis.

Jankowiak W, Kruszewski K, Flachsbarth K, Skevas C, Richard G, Rüther K, Braulke T, Bartsch U.

PLoS One. 2015 May 20;10(5):e0127204. doi: 10.1371/journal.pone.0127204. eCollection 2015.

14.

Translational neurophysiology in sheep: measuring sleep and neurological dysfunction in CLN5 Batten disease affected sheep.

Perentos N, Martins AQ, Watson TC, Bartsch U, Mitchell NL, Palmer DN, Jones MW, Morton AJ.

Brain. 2015 Apr;138(Pt 4):862-74. doi: 10.1093/brain/awv026. Epub 2015 Feb 26.

15.

The sheddase ADAM10 is a potent modulator of prion disease.

Altmeppen HC, Prox J, Krasemann S, Puig B, Kruszewski K, Dohler F, Bernreuther C, Hoxha A, Linsenmeier L, Sikorska B, Liberski PP, Bartsch U, Saftig P, Glatzel M.

Elife. 2015 Feb 5;4. doi: 10.7554/eLife.04260.

16.

Disrupted hippocampal sharp-wave ripple-associated spike dynamics in a transgenic mouse model of dementia.

Witton J, Staniaszek LE, Bartsch U, Randall AD, Jones MW, Brown JT.

J Physiol. 2016 Aug 15;594(16):4615-30. doi: 10.1113/jphysiol.2014.282889. Epub 2015 Jan 2.

17.

CEACAM1 confers resistance toward oxygen-induced vessel damage in a mouse model of retinopathy of prematurity.

Ludewig P, Flachsbarth K, Wegscheid C, Tiegs G, Richard G, Wagener C, Bartsch U, Horst AK.

Invest Ophthalmol Vis Sci. 2014 Nov 18;55(12):7950-60. doi: 10.1167/iovs.13-13403.

PMID:
25406283
18.

Neural stem cell-based intraocular administration of ciliary neurotrophic factor attenuates the loss of axotomized ganglion cells in adult mice.

Flachsbarth K, Kruszewski K, Jung G, Jankowiak W, Riecken K, Wagenfeld L, Richard G, Fehse B, Bartsch U.

Invest Ophthalmol Vis Sci. 2014 Sep 30;55(11):7029-39. doi: 10.1167/iovs.14-15266.

PMID:
25270193
19.

Neural oscillations during non-rapid eye movement sleep as biomarkers of circuit dysfunction in schizophrenia.

Gardner RJ, Kersanté F, Jones MW, Bartsch U.

Eur J Neurosci. 2014 Apr;39(7):1091-106. doi: 10.1111/ejn.12533. Review.

PMID:
24712989
20.

Gene disruption of Mfsd8 in mice provides the first animal model for CLN7 disease.

Damme M, Brandenstein L, Fehr S, Jankowiak W, Bartsch U, Schweizer M, Hermans-Borgmeyer I, Storch S.

Neurobiol Dis. 2014 May;65:12-24. doi: 10.1016/j.nbd.2014.01.003. Epub 2014 Jan 11.

PMID:
24423645
21.

Combination therapy targeting integrins reduces glioblastoma tumor growth through antiangiogenic and direct antitumor activity and leads to activation of the pro-proliferative prolactin pathway.

Oliveira-Ferrer L, Wellbrock J, Bartsch U, Penas EM, Hauschild J, Klokow M, Bokemeyer C, Fiedler W, Schuch G.

Mol Cancer. 2013 Nov 20;12(1):144. doi: 10.1186/1476-4598-12-144.

22.

Nonneuronal control of the differential distribution of myelin along retinal ganglion cell axons in the mouse.

Yang X, Zou H, Jung G, Richard G, Linke SJ, Ader M, Bartsch U.

Invest Ophthalmol Vis Sci. 2013 Dec 2;54(13):7819-27. doi: 10.1167/iovs.13-12596.

PMID:
24222305
23.

Genetically modified neural stem cells for a local and sustained delivery of neuroprotective factors to the dystrophic mouse retina.

Jung G, Sun J, Petrowitz B, Riecken K, Kruszewski K, Jankowiak W, Kunst F, Skevas C, Richard G, Fehse B, Bartsch U.

Stem Cells Transl Med. 2013 Dec;2(12):1001-10. doi: 10.5966/sctm.2013-0013. Epub 2013 Oct 28.

24.

Apoptotic photoreceptor loss and altered expression of lysosomal proteins in the nclf mouse model of neuronal ceroid lipofuscinosis.

Bartsch U, Galliciotti G, Jofre GF, Jankowiak W, Hagel C, Braulke T.

Invest Ophthalmol Vis Sci. 2013 Oct 23;54(10):6952-9. doi: 10.1167/iovs.13-12945.

PMID:
24084090
25.

Decoupling of sleep-dependent cortical and hippocampal interactions in a neurodevelopmental model of schizophrenia.

Phillips KG, Bartsch U, McCarthy AP, Edgar DM, Tricklebank MD, Wafford KA, Jones MW.

Neuron. 2012 Nov 8;76(3):526-33. doi: 10.1016/j.neuron.2012.09.016.

26.

In vitro expanded stem cells from the developing retina fail to generate photoreceptors but differentiate into myelinating oligodendrocytes.

Czekaj M, Haas J, Gebhardt M, Müller-Reichert T, Humphries P, Farrar J, Bartsch U, Ader M.

PLoS One. 2012;7(7):e41798. doi: 10.1371/journal.pone.0041798. Epub 2012 Jul 25.

27.

A novel missense mutation T101N in the melanocortin-4 receptor gene associated with obesity.

Buchbinder S, Bärtsch U, Müller M, Zorn M, Nawroth PP, Schilling T.

Genet Mol Res. 2011 Jun 7;10(2):1042-9. doi: 10.4238/vol10-2gmr948.

28.

Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo.

Altmeppen HC, Prox J, Puig B, Kluth MA, Bernreuther C, Thurm D, Jorissen E, Petrowitz B, Bartsch U, De Strooper B, Saftig P, Glatzel M.

Mol Neurodegener. 2011 May 27;6:36. doi: 10.1186/1750-1326-6-36.

29.

GDNF-induced osteopontin from Müller glial cells promotes photoreceptor survival in the Pde6brd1 mouse model of retinal degeneration.

Del Río P, Irmler M, Arango-González B, Favor J, Bobe C, Bartsch U, Vecino E, Beckers J, Hauck SM, Ueffing M.

Glia. 2011 May;59(5):821-32. doi: 10.1002/glia.21155. Epub 2011 Feb 28.

PMID:
21360756
30.

L1 and CHL1 Cooperate in Thalamocortical Axon Targeting.

Demyanenko GP, Siesser PF, Wright AG, Brennaman LH, Bartsch U, Schachner M, Maness PF.

Cereb Cortex. 2011 Feb;21(2):401-12. doi: 10.1093/cercor/bhq115. Epub 2010 Jun 24.

31.

The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex.

Jorissen E, Prox J, Bernreuther C, Weber S, Schwanbeck R, Serneels L, Snellinx A, Craessaerts K, Thathiah A, Tesseur I, Bartsch U, Weskamp G, Blobel CP, Glatzel M, De Strooper B, Saftig P.

J Neurosci. 2010 Apr 7;30(14):4833-44. doi: 10.1523/JNEUROSCI.5221-09.2010.

32.

Lentiviral gene ontology (LeGO) vectors equipped with novel drug-selectable fluorescent proteins: new building blocks for cell marking and multi-gene analysis.

Weber K, Mock U, Petrowitz B, Bartsch U, Fehse B.

Gene Ther. 2010 Apr;17(4):511-20. doi: 10.1038/gt.2009.149. Epub 2009 Dec 17.

PMID:
20016542
33.

[Oxidative stress at the retinal pigment epithelium - experimental implications for protection].

Zeitz O, Berna-Thill M, Bartsch U, Strauss O, Richard G.

Klin Monbl Augenheilkd. 2009 Jan;226(1):27-30. doi: 10.1055/s-2008-1027600. Epub 2009 Jan 27. Review. German.

PMID:
19173160
34.

A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis.

Weber K, Bartsch U, Stocking C, Fehse B.

Mol Ther. 2008 Apr;16(4):698-706. doi: 10.1038/mt.2008.6. Epub 2008 Feb 12.

35.

Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice.

Bartsch U, Oriyakhel W, Kenna PF, Linke S, Richard G, Petrowitz B, Humphries P, Farrar GJ, Ader M.

Exp Eye Res. 2008 Apr;86(4):691-700. doi: 10.1016/j.exer.2008.01.018. Epub 2008 Feb 3.

PMID:
18329018
36.

Development of the corticospinal tract in Semaphorin3A- and CD24-deficient mice.

Sibbe M, Taniguchi M, Schachner M, Bartsch U.

Neuroscience. 2007 Dec 19;150(4):898-904. Epub 2007 Oct 18.

PMID:
18022325
37.

[Insulin pens for treatment of diabetes].

Bärtsch U, Comtesse Ch, Wetekam B.

Ther Umsch. 2006 Jun;63(6):398-404. Review. German.

PMID:
16841576
38.

Regional and cellular distribution of the extracellular matrix protein tenascin-C in the chick forebrain and its role in neonatal learning.

Metzger M, Bartsch S, Bartsch U, Bock J, Schachner M, Braun K.

Neuroscience. 2006 Sep 15;141(4):1709-19. Epub 2006 Jun 22.

PMID:
16797128
39.

[How do you manage difficult patients? (interview by Friederike Klein)].

Rendenbach U, Michel W, Pohl D, Bartsch U.

MMW Fortschr Med. 2006 Mar 9;148(10):14-5. German. No abstract available.

PMID:
16612941
40.

In vivo confocal microscopy of pre-endothelial deposits.

Linke S, Bartsch U, Richard G, Klemm M.

Graefes Arch Clin Exp Ophthalmol. 2007 Feb;245(2):309-12.

PMID:
16550401
41.

Locally applied mononuclear bone marrow cells restore angiogenesis and promote wound healing in a type 2 diabetic patient.

Humpert PM, Bärtsch U, Konrade I, Hammes HP, Morcos M, Kasper M, Bierhaus A, Nawroth PP.

Exp Clin Endocrinol Diabetes. 2005 Oct;113(9):538-40.

PMID:
16235157
42.

[Therapeutic strategies for hereditary retinal diseases].

Rüther K, Bartsch U.

Ophthalmologe. 2005 Aug;102(8):755-6. German. No abstract available.

PMID:
15999275
43.

Electroporation-based gene transfer for efficient transfection of neural precursor cells.

Richard I, Ader M, Sytnyk V, Dityatev A, Richard G, Schachner M, Bartsch U.

Brain Res Mol Brain Res. 2005 Aug 18;138(2):182-90.

PMID:
15908040
44.

[Therapeutic strategies for hereditary retinal diseases]].

Bartsch U, Rüther K.

Ophthalmologe. 2005 Jul;102(7):659-60. German. No abstract available.

PMID:
15883845
45.

[Stem cell-based therapies for retinal disorders].

Bartsch U, Linke SJ, Petrowitz B.

Ophthalmologe. 2005 Jul;102(7):679-87. Review. German.

PMID:
15871024
46.

Reduction of postprandial hyperglycemia in patients with type 2 diabetes reduces NF-kappaB activation in PBMCs.

Rudofsky G Jr, Reismann P, Schiekofer S, Petrov D, von Eynatten M, Humpert PM, Isermann B, Müller-Hoff C, Thai TP, Lichtenstein S, Bärtsch U, Hamann A, Nawroth P, Bierhaus A.

Horm Metab Res. 2004 Sep;36(9):630-8.

PMID:
15486815
47.
48.
49.

The raft-associated protein MAL is required for maintenance of proper axon--glia interactions in the central nervous system.

Schaeren-Wiemers N, Bonnet A, Erb M, Erne B, Bartsch U, Kern F, Mantei N, Sherman D, Suter U.

J Cell Biol. 2004 Aug 30;166(5):731-42.

50.

Reduced GABAergic transmission and number of hippocampal perisomatic inhibitory synapses in juvenile mice deficient in the neural cell adhesion molecule L1.

Saghatelyan AK, Nikonenko AG, Sun M, Rolf B, Putthoff P, Kutsche M, Bartsch U, Dityatev A, Schachner M.

Mol Cell Neurosci. 2004 May;26(1):191-203.

PMID:
15121190

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