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Items: 1 to 50 of 350

1.

Nitric Oxide Modulates Endonuclease III Redox Activity by a 800 mV Negative Shift upon [Fe4S4] Cluster Nitrosylation.

Ekanger LA, Oyala PH, Moradian A, Sweredoski MJ, Barton JK.

J Am Chem Soc. 2018 Sep 19;140(37):11800-11810. doi: 10.1021/jacs.8b07362. Epub 2018 Sep 6.

PMID:
30145881
2.

A human MUTYH variant linking colonic polyposis to redox degradation of the [4Fe4S]2+ cluster.

McDonnell KJ, Chemler JA, Bartels PL, O'Brien E, Marvin ML, Ortega J, Stern RH, Raskin L, Li GM, Sherman DH, Barton JK, Gruber SB.

Nat Chem. 2018 Aug;10(8):873-880. doi: 10.1038/s41557-018-0068-x. Epub 2018 Jun 18.

3.

Sensing DNA through DNA Charge Transport.

Zwang TJ, Tse ECM, Barton JK.

ACS Chem Biol. 2018 Jul 20;13(7):1799-1809. doi: 10.1021/acschembio.8b00347. Epub 2018 Jun 1.

4.

Compact fiber-based multi-photon endoscope working at 1700 nm.

Akhoundi F, Qin Y, Peyghambarian N, Barton JK, Kieu K.

Biomed Opt Express. 2018 Apr 25;9(5):2326-2335. doi: 10.1364/BOE.9.002326. eCollection 2018 May 1.

5.

A Compass at Weak Magnetic Fields Using Thymine Dimer Repair.

Zwang TJ, Tse ECM, Zhong D, Barton JK.

ACS Cent Sci. 2018 Mar 28;4(3):405-412. doi: 10.1021/acscentsci.8b00008. Epub 2018 Mar 7.

6.

A Family of Rhodium Complexes with Selective Toxicity toward Mismatch Repair-Deficient Cancers.

Boyle KM, Barton JK.

J Am Chem Soc. 2018 Apr 25;140(16):5612-5624. doi: 10.1021/jacs.8b02271. Epub 2018 Apr 17.

7.

A Redox Role for the [4Fe4S] Cluster of Yeast DNA Polymerase δ.

Bartels PL, Stodola JL, Burgers PMJ, Barton JK.

J Am Chem Soc. 2017 Dec 20;139(50):18339-18348. doi: 10.1021/jacs.7b10284. Epub 2017 Dec 6.

8.

A Rhodium-Cyanine Fluorescent Probe: Detection and Signaling of Mismatches in DNA.

Nano A, Boynton AN, Barton JK.

J Am Chem Soc. 2017 Dec 6;139(48):17301-17304. doi: 10.1021/jacs.7b10639. Epub 2017 Nov 21.

9.

Does Mutated K-RAS Oncogene Attenuate the Effect of Sulindac in Colon Cancer Chemoprevention?

Rice PFS, Ehrichs KG, Jones MS, Chen H, Hsu CH, Abril ER, Nagle RB, Besselsen DG, Barton JK, Ignatenko NA.

Cancer Prev Res (Phila). 2018 Jan;11(1):16-26. doi: 10.1158/1940-6207.CAPR-17-0230. Epub 2017 Nov 8.

PMID:
29118162
10.

Wavelength-coded volume holographic imaging endoscope for multidepth imaging.

Howlett ID, Han W, Rice P, Barton JK, Kostuk RK.

J Biomed Opt. 2017 Oct;22(10):1-4. doi: 10.1117/1.JBO.22.10.100501.

PMID:
28971662
11.

The Oxidation State of [4Fe4S] Clusters Modulates the DNA-Binding Affinity of DNA Repair Proteins.

Tse ECM, Zwang TJ, Barton JK.

J Am Chem Soc. 2017 Sep 13;139(36):12784-12792. doi: 10.1021/jacs.7b07230. Epub 2017 Aug 29.

12.

Response to Comments on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport".

O'Brien E, Holt ME, Thompson MK, Salay LE, Ehlinger AC, Chazin WJ, Barton JK.

Science. 2017 Jul 21;357(6348). pii: eaan2762. doi: 10.1126/science.aan2762.

13.

Sulfur K-Edge XAS Studies of the Effect of DNA Binding on the [Fe4S4] Site in EndoIII and MutY.

Ha Y, Arnold AR, Nuñez NN, Bartels PL, Zhou A, David SS, Barton JK, Hedman B, Hodgson KO, Solomon EI.

J Am Chem Soc. 2017 Aug 23;139(33):11434-11442. doi: 10.1021/jacs.7b03966. Epub 2017 Aug 10.

14.

A Ruthenium(II) Complex as a Luminescent Probe for DNA Mismatches and Abasic Sites.

Boynton AN, Marcélis L, McConnell AJ, Barton JK.

Inorg Chem. 2017 Jul 17;56(14):8381-8389. doi: 10.1021/acs.inorgchem.7b01037. Epub 2017 Jun 28.

15.

Electrical Probes of DNA-Binding Proteins.

Barton JK, Bartels PL, Deng Y, O'Brien E.

Methods Enzymol. 2017;591:355-414. doi: 10.1016/bs.mie.2017.03.024. Epub 2017 May 10.

PMID:
28645377
16.

Rhodium metalloinsertor binding generates a lesion with selective cytotoxicity for mismatch repair-deficient cells.

Bailis JM, Weidmann AG, Mariano NF, Barton JK.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):6948-6953. doi: 10.1073/pnas.1706665114. Epub 2017 Jun 20.

17.

Intermittent Dosing with Sulindac Provides Effective Colorectal Cancer Chemoprevention in the Azoxymethane-Treated Mouse Model.

Chandra S, Nymeyer AC, Rice PF, Gerner EW, Barton JK.

Cancer Prev Res (Phila). 2017 Aug;10(8):459-466. doi: 10.1158/1940-6207.CAPR-17-0038. Epub 2017 Jun 13.

18.

Volume holographic imaging endoscopic design and construction techniques.

Howlett ID, Han W, Gordon M, Rice P, Barton JK, Kostuk RK.

J Biomed Opt. 2017 May 1;22(5):56010. doi: 10.1117/1.JBO.22.5.056010.

19.

Ultraminiature optical design for multispectral fluorescence imaging endoscopes.

Tate TH, Keenan M, Black J, Utzinger U, Barton JK.

J Biomed Opt. 2017 Mar 1;22(3):36013. doi: 10.1117/1.JBO.22.3.036013.

20.

The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.

O'Brien E, Holt ME, Thompson MK, Salay LE, Ehlinger AC, Chazin WJ, Barton JK.

Science. 2017 Feb 24;355(6327). pii: eaag1789. doi: 10.1126/science.aag1789.

21.

Electrochemistry of the [4Fe4S] Cluster in Base Excision Repair Proteins: Tuning the Redox Potential with DNA.

Bartels PL, Zhou A, Arnold AR, Nuñez NN, Crespilho FN, David SS, Barton JK.

Langmuir. 2017 Mar 14;33(10):2523-2530. doi: 10.1021/acs.langmuir.6b04581. Epub 2017 Mar 2.

22.

Design and characterization of a combined OCT and wide field imaging falloposcope for ovarian cancer detection.

Keenan M, Tate TH, Kieu K, Black JF, Utzinger U, Barton JK.

Biomed Opt Express. 2016 Dec 8;8(1):124-136. doi: 10.1364/BOE.8.000124. eCollection 2017 Jan 1.

23.

Redox Signaling through DNA.

O'Brien E, Silva RM, Barton JK.

Isr J Chem. 2016 Oct;56(9-10):705-723. doi: 10.1002/ijch.201600022. Epub 2016 Jul 29.

24.

Helix-Dependent Spin Filtering through the DNA Duplex.

Zwang TJ, Hürlimann S, Hill MG, Barton JK.

J Am Chem Soc. 2016 Dec 7;138(48):15551-15554. Epub 2016 Nov 22.

25.

Targeting DNA Mismatches with Rhodium Metalloinsertors.

Boyle KM, Barton JK.

Inorganica Chim Acta. 2016 Oct 1;452:3-11. Epub 2016 Jan 16.

26.

Characterization of the DNA-Mediated Oxidation of Dps, A Bacterial Ferritin.

Arnold AR, Zhou A, Barton JK.

J Am Chem Soc. 2016 Sep 7;138(35):11290-8. doi: 10.1021/jacs.6b06507. Epub 2016 Aug 29.

27.

In vivo endoscopic Doppler optical coherence tomography imaging of the colon.

Welge WA, Barton JK.

Lasers Surg Med. 2017 Mar;49(3):249-257. doi: 10.1002/lsm.22578. Epub 2016 Aug 22.

28.

Multispectral fluorescence imaging of human ovarian and fallopian tube tissue for early-stage cancer detection.

Tate TH, Baggett B, Rice PF, Koevary JW, Orsinger GV, Nymeyer AC, Welge WA, Saboda K, Roe DJ, Hatch KD, Chambers SK, Utzinger U, Barton JK.

J Biomed Opt. 2016 May 1;21(5):56005. doi: 10.1117/1.JBO.21.5.056005.

29.

[Ru(Me4phen)2dppz](2+), a Light Switch for DNA Mismatches.

Boynton AN, Marcélis L, Barton JK.

J Am Chem Soc. 2016 Apr 20;138(15):5020-3. doi: 10.1021/jacs.6b02022. Epub 2016 Apr 12.

30.

DNA Charge Transport: from Chemical Principles to the Cell.

Arnold AR, Grodick MA, Barton JK.

Cell Chem Biol. 2016 Jan 21;23(1):183-197. doi: 10.1016/j.chembiol.2015.11.010. Review.

31.

Imaging colon cancer development in mice: IL-6 deficiency prevents adenoma in azoxymethane-treated Smad3 knockouts.

Harpel K, Leung S, Rice PF, Jones M, Barton JK, Bommireddy R.

Phys Med Biol. 2016 Feb 7;61(3):N60-9. doi: 10.1088/0031-9155/61/3/N60. Epub 2016 Jan 13.

PMID:
26758693
32.

Expanding Functionality of Commercial Optical Coherence Tomography Systems by Integrating a Custom Endoscope.

Welge WA, Barton JK.

PLoS One. 2015 Sep 29;10(9):e0139396. doi: 10.1371/journal.pone.0139396. eCollection 2015.

33.

A monofunctional platinum complex coordinated to a rhodium metalloinsertor selectively binds mismatched DNA in the minor groove.

Weidmann AG, Barton JK.

Inorg Chem. 2015 Oct 5;54(19):9626-36. doi: 10.1021/acs.inorgchem.5b01722. Epub 2015 Sep 23.

35.

Time-serial Assessment of Drug Combination Interventions in a Mouse Model of Colorectal Carcinogenesis Using Optical Coherence Tomography.

LeGendre-McGhee S, Rice PS, Wall RA, Sprute KJ, Bommireddy R, Luttman AM, Nagle RB, Abril ER, Farrell K, Hsu CH, Roe DJ, Gerner EW, Ignatenko NA, Barton JK.

Cancer Growth Metastasis. 2015 Sep 7;8(Suppl 1):63-80. doi: 10.4137/CGM.S21216. eCollection 2015.

36.

DNA Electrochemistry Shows DNMT1 Methyltransferase Hyperactivity in Colorectal Tumors.

Furst AL, Barton JK.

Chem Biol. 2015 Jul 23;22(7):938-45. doi: 10.1016/j.chembiol.2015.05.019. Epub 2015 Jun 25.

37.

A Multiplexed, Two-Electrode Platform for Biosensing Based on DNA-Mediated Charge Transport.

Furst AL, Hill MG, Barton JK.

Langmuir. 2015 Jun 16;31(23):6554-62. doi: 10.1021/acs.langmuir.5b00829. Epub 2015 Jun 4.

38.

Diagnostic potential of multimodal imaging of ovarian tissue using optical coherence tomography and second-harmonic generation microscopy.

Welge WA, DeMarco AT, Watson JM, Rice PS, Barton JK, Kupinski MA.

J Med Imaging (Bellingham). 2014 Jul 18;1(2):025501.

39.

Targeted Chemotherapy with Metal Complexes.

Weidmann AG, Komor AC, Barton JK.

Comments Mod Chem A Comments Inorg Chem. 2014 May;34(3-4):114-123.

40.

DNA charge transport within the cell.

Grodick MA, Muren NB, Barton JK.

Biochemistry. 2015 Feb 3;54(4):962-73. doi: 10.1021/bi501520w. Epub 2015 Jan 21. Review.

41.

Oxidation of p53 through DNA charge transport involves a network of disulfides within the DNA-binding domain.

Schaefer KN, Geil WM, Sweredoski MJ, Moradian A, Hess S, Barton JK.

Biochemistry. 2015 Jan 27;54(3):932-41. doi: 10.1021/bi501424v. Epub 2015 Jan 13.

42.

In vivo molecular mapping of the tumor microenvironment in an azoxymethane-treated mouse model of colon carcinogenesis.

Leung SJ, Rice PS, Barton JK.

Lasers Surg Med. 2015 Jan;47(1):40-9. doi: 10.1002/lsm.22309. Epub 2014 Dec 9.

43.

Dual optical modality endoscopic imaging of cancer development in the mouse colon.

Keenan MR, Leung SJ, Rice PS, Wall RA, Barton JK.

Lasers Surg Med. 2015 Jan;47(1):30-9. doi: 10.1002/lsm.22307. Epub 2014 Dec 1.

44.

Electrocatalysis in DNA Sensors.

Furst A, Hill MG, Barton JK.

Polyhedron. 2014 Dec 14;84:150-159.

45.

Label-free electrochemical detection of human methyltransferase from tumors.

Furst AL, Muren NB, Hill MG, Barton JK.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):14985-9. doi: 10.1073/pnas.1417351111. Epub 2014 Oct 6.

46.

An unusual ligand coordination gives rise to a new family of rhodium metalloinsertors with improved selectivity and potency.

Komor AC, Barton JK.

J Am Chem Soc. 2014 Oct 8;136(40):14160-72. doi: 10.1021/ja5072064. Epub 2014 Sep 25.

47.

Quantum dots targeted to vascular endothelial growth factor receptor 2 as a contrast agent for the detection of colorectal cancer.

Carbary-Ganz JL, Barton JK, Utzinger U.

J Biomed Opt. 2014 Aug;19(8):086003. doi: 10.1117/1.JBO.19.8.086003.

48.

Construction and application of a Rh-Pt DNA metalloinsertor conjugate.

Weidmann AG, Barton JK.

Inorg Chem. 2014 Aug 4;53(15):7812-4. doi: 10.1021/ic501509x. Epub 2014 Jul 17.

49.

Volume Holographic Reflection Endoscope for In-Vivo Ovarian Cancer Clinical Studies.

Howlett ID, Gordon M, Brownlee JW, Barton JK, Kostuk RK.

Proc SPIE Int Soc Opt Eng. 2014 Mar 4;2014. doi: 10.1117/12.2037859.

50.

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