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Items: 36


Effect of Active and Early Possible Organ and Tissue Donor Detection in the Emergency Room in a University Hospital.

Budoy D, Rodriguez-Villar C, Peña D, Vizcaino F, Saavedra S, Bohils M, Quijada M, Manuel de la Cruz J, Paredes-Zapata D, Ruiz A, Roque R, Garcia X, Bartolome RA.

Transplant Proc. 2019 Nov;51(9):3027-3029. doi: 10.1016/j.transproceed.2019.08.022. Epub 2019 Oct 16.


Beyond N-Cadherin, Relevance of Cadherins 5, 6 and 17 in Cancer Progression and Metastasis.

Casal JI, Bartolomé RA.

Int J Mol Sci. 2019 Jul 9;20(13). pii: E3373. doi: 10.3390/ijms20133373. Review.


PAUF/ZG16B promotes colorectal cancer progression through alterations of the mitotic functions and the Wnt/β-catenin pathway.

Escudero-Paniagua B, Bartolomé RA, Rodríguez S, de Los Ríos V, Pintado L, Jaen M, Lafarga M, Fernández-Aceñero MJ, Casal JI.

Carcinogenesis. 2019 May 17. pii: bgz093. doi: 10.1093/carcin/bgz093. [Epub ahead of print]


PIM kinases mediate resistance of glioblastoma cells to TRAIL by a p62/SQSTM1-dependent mechanism.

Serrano-Saenz S, Palacios C, Delgado-Bellido D, López-Jiménez L, Garcia-Diaz A, Soto-Serrano Y, Casal JI, Bartolomé RA, Fernández-Luna JL, López-Rivas A, Oliver FJ.

Cell Death Dis. 2019 Jan 18;10(2):51. doi: 10.1038/s41419-018-1293-3.


An IL13Rα2 peptide exhibits therapeutic activity against metastatic colorectal cancer.

Bartolomé RA, Jaén M, Casal JI.

Br J Cancer. 2018 Oct;119(8):940-949. doi: 10.1038/s41416-018-0259-7. Epub 2018 Oct 15.


RGD cadherins and α2β1 integrin in cancer metastasis: A dangerous liaison.

Casal JI, Bartolomé RA.

Biochim Biophys Acta Rev Cancer. 2018 Apr;1869(2):321-332. doi: 10.1016/j.bbcan.2018.04.005. Epub 2018 Apr 17. Review.


Proteomic Characterization of Transcription and Splicing Factors Associated with a Metastatic Phenotype in Colorectal Cancer.

Torres S, García-Palmero I, Marín-Vicente C, Bartolomé RA, Calviño E, Fernández-Aceñero MJ, Casal JI.

J Proteome Res. 2018 Jan 5;17(1):252-264. doi: 10.1021/acs.jproteome.7b00548. Epub 2017 Nov 21.


Monoclonal Antibodies Directed against Cadherin RGD Exhibit Therapeutic Activity against Melanoma and Colorectal Cancer Metastasis.

Bartolomé RA, Aizpurua C, Jaén M, Torres S, Calviño E, Imbaud JI, Casal JI.

Clin Cancer Res. 2018 Jan 15;24(2):433-444. doi: 10.1158/1078-0432.CCR-17-1444. Epub 2017 Sep 15.


Mapping the Spatial Proteome of Metastatic Cells in Colorectal Cancer.

Mendes M, Peláez-García A, López-Lucendo M, Bartolomé RA, Calviño E, Barderas R, Casal JI.

Proteomics. 2017 Oct;17(19). doi: 10.1002/pmic.201700094.


Combined miRNA profiling and proteomics demonstrates that different miRNAs target a common set of proteins to promote colorectal cancer metastasis.

Torres S, Garcia-Palmero I, Bartolomé RA, Fernandez-Aceñero MJ, Molina E, Calviño E, Segura MF, Casal JI.

J Pathol. 2017 May;242(1):39-51. doi: 10.1002/path.4874. Epub 2017 Mar 7.


VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers.

Bartolomé RA, Torres S, Isern de Val S, Escudero-Paniagua B, Calviño E, Teixidó J, Casal JI.

Oncotarget. 2017 Jan 3;8(1):215-227. doi: 10.18632/oncotarget.13832.


Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI).

García-Palmero I, Torres S, Bartolomé RA, Peláez-García A, Larriba MJ, Lopez-Lucendo M, Peña C, Escudero-Paniagua B, Muñoz A, Casal JI.

Oncogene. 2016 Oct 6;35(40):5224-5236. doi: 10.1038/onc.2016.57. Epub 2016 Mar 14.


IL13Rα2 signaling in colorectal cancer.

Bartolomé RA, Casal JI.

Oncoscience. 2015 Sep 12;2(10):787-8. eCollection 2015. No abstract available.


LOXL2 Is Highly Expressed in Cancer-Associated Fibroblasts and Associates to Poor Colon Cancer Survival.

Torres S, Garcia-Palmero I, Herrera M, Bartolomé RA, Peña C, Fernandez-Aceñero MJ, Padilla G, Peláez-García A, Lopez-Lucendo M, Rodriguez-Merlo R, García de Herreros A, Bonilla F, Casal JI.

Clin Cancer Res. 2015 Nov 1;21(21):4892-902. doi: 10.1158/1078-0432.CCR-14-3096. Epub 2015 Jul 23.


IL13 Receptor α2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.

Bartolomé RA, García-Palmero I, Torres S, López-Lucendo M, Balyasnikova IV, Casal JI.

Cancer Res. 2015 Jun 15;75(12):2434-44. doi: 10.1158/0008-5472.CAN-14-3650. Epub 2015 Apr 20.


A proteomic analysis reveals that Snail regulates the expression of the nuclear orphan receptor Nuclear Receptor Subfamily 2 Group F Member 6 (Nr2f6) and interleukin 17 (IL-17) to inhibit adipocyte differentiation.

Peláez-García A, Barderas R, Batlle R, Viñas-Castells R, Bartolomé RA, Torres S, Mendes M, Lopez-Lucendo M, Mazzolini R, Bonilla F, García de Herreros A, Casal JI.

Mol Cell Proteomics. 2015 Feb;14(2):303-15. doi: 10.1074/mcp.M114.045328. Epub 2014 Dec 10.


An RGD motif present in cadherin 17 induces integrin activation and tumor growth.

Bartolomé RA, Peláez-García A, Gomez I, Torres S, Fernandez-Aceñero MJ, Escudero-Paniagua B, Imbaud JI, Casal JI.

J Biol Chem. 2014 Dec 12;289(50):34801-14. doi: 10.1074/jbc.M114.600502. Epub 2014 Oct 21.


A Blk-p190RhoGAP signaling module downstream of activated Gα13 functionally opposes CXCL12-stimulated RhoA activation and cell invasion.

Bartolomé RA, Díaz-Martínez M, Coló GP, Arellano-Sánchez N, Torres-Ayuso P, Kleinovink JW, Mérida I, Teixidó J.

Cell Signal. 2014 Nov;26(11):2551-61. doi: 10.1016/j.cellsig.2014.07.008. Epub 2014 Jul 13.


Proteome profiling of cancer-associated fibroblasts identifies novel proinflammatory signatures and prognostic markers for colorectal cancer.

Torres S, Bartolomé RA, Mendes M, Barderas R, Fernandez-Aceñero MJ, Peláez-García A, Peña C, Lopez-Lucendo M, Villar-Vázquez R, de Herreros AG, Bonilla F, Casal JI.

Clin Cancer Res. 2013 Nov 1;19(21):6006-19. doi: 10.1158/1078-0432.CCR-13-1130. Epub 2013 Sep 11.


Cadherin-17 interacts with α2β1 integrin to regulate cell proliferation and adhesion in colorectal cancer cells causing liver metastasis.

Bartolomé RA, Barderas R, Torres S, Fernandez-Aceñero MJ, Mendes M, García-Foncillas J, Lopez-Lucendo M, Casal JI.

Oncogene. 2014 Mar 27;33(13):1658-69. doi: 10.1038/onc.2013.117. Epub 2013 Apr 22.


In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion.

Barderas R, Mendes M, Torres S, Bartolomé RA, López-Lucendo M, Villar-Vázquez R, Peláez-García A, Fuente E, Bonilla F, Casal JI.

Mol Cell Proteomics. 2013 Jun;12(6):1602-20. doi: 10.1074/mcp.M112.022848. Epub 2013 Feb 26.


Focal adhesion disassembly is regulated by a RIAM to MEK-1 pathway.

Coló GP, Hernández-Varas P, Lock J, Bartolomé RA, Arellano-Sánchez N, Strömblad S, Teixidó J.

J Cell Sci. 2012 Nov 15;125(Pt 22):5338-52. doi: 10.1242/jcs.105270. Epub 2012 Sep 3.


High expression of IL-13 receptor α2 in colorectal cancer is associated with invasion, liver metastasis, and poor prognosis.

Barderas R, Bartolomé RA, Fernandez-Aceñero MJ, Torres S, Casal JI.

Cancer Res. 2012 Jun 1;72(11):2780-90. doi: 10.1158/0008-5472.CAN-11-4090. Epub 2012 Apr 13.


Rap1-GTP-interacting adaptor molecule (RIAM) protein controls invasion and growth of melanoma cells.

Hernández-Varas P, Coló GP, Bartolomé RA, Paterson A, Medraño-Fernández I, Arellano-Sánchez N, Cabañas C, Sánchez-Mateos P, Lafuente EM, Boussiotis VA, Strömblad S, Teixidó J.

J Biol Chem. 2011 May 27;286(21):18492-504. doi: 10.1074/jbc.M110.189811. Epub 2011 Mar 26.


Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complex.

Fernández IS, Yamashita A, Arias-Palomo E, Bamba Y, Bartolomé RA, Canales MA, Teixidó J, Ohno S, Llorca O.

Nucleic Acids Res. 2011 Jan;39(1):347-58. doi: 10.1093/nar/gkq749. Epub 2010 Sep 3.


MT1-MMP is required for myeloid cell fusion via regulation of Rac1 signaling.

Gonzalo P, Guadamillas MC, Hernández-Riquer MV, Pollán A, Grande-García A, Bartolomé RA, Vasanji A, Ambrogio C, Chiarle R, Teixidó J, Risteli J, Apte SS, del Pozo MA, Arroyo AG.

Dev Cell. 2010 Jan 19;18(1):77-89. doi: 10.1016/j.devcel.2009.11.012.


Moesin orchestrates cortical polarity of melanoma tumour cells to initiate 3D invasion.

Estecha A, Sánchez-Martín L, Puig-Kröger A, Bartolomé RA, Teixidó J, Samaniego R, Sánchez-Mateos P.

J Cell Sci. 2009 Oct 1;122(Pt 19):3492-501. doi: 10.1242/jcs.053157. Epub 2009 Sep 1.


Overexpression of E-cadherin on melanoma cells inhibits chemokine-promoted invasion involving p190RhoGAP/p120ctn-dependent inactivation of RhoA.

Molina-Ortiz I, Bartolomé RA, Hernández-Varas P, Colo GP, Teixidó J.

J Biol Chem. 2009 May 29;284(22):15147-57. doi: 10.1074/jbc.M807834200. Epub 2009 Mar 17.


The chemokine receptor CXCR4 and the metalloproteinase MT1-MMP are mutually required during melanoma metastasis to lungs.

Bartolomé RA, Ferreiro S, Miquilena-Colina ME, Martínez-Prats L, Soto-Montenegro ML, García-Bernal D, Vaquero JJ, Agami R, Delgado R, Desco M, Sánchez-Mateos P, Teixidó J.

Am J Pathol. 2009 Feb;174(2):602-12. doi: 10.2353/ajpath.2009.080636. Epub 2009 Jan 15.


Polarized MT1-MMP-CD44 interaction and CD44 cleavage during cell retraction reveal an essential role for MT1-MMP in CD44-mediated invasion.

Marrero-Diaz R, Bravo-Cordero JJ, Megías D, García MA, Bartolomé RA, Teixido J, Montoya MC.

Cell Motil Cytoskeleton. 2009 Jan;66(1):48-61. doi: 10.1002/cm.20325.


Activated G(alpha)13 impairs cell invasiveness through p190RhoGAP-mediated inhibition of RhoA activity.

Bartolomé RA, Wright N, Molina-Ortiz I, Sánchez-Luque FJ, Teixidó J.

Cancer Res. 2008 Oct 15;68(20):8221-30. doi: 10.1158/0008-5472.CAN-08-0561.


Activation of Vav/Rho GTPase signaling by CXCL12 controls membrane-type matrix metalloproteinase-dependent melanoma cell invasion.

Bartolomé RA, Molina-Ortiz I, Samaniego R, Sánchez-Mateos P, Bustelo XR, Teixidó J.

Cancer Res. 2006 Jan 1;66(1):248-58.


Stromal cell-derived factor-1alpha promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities.

Bartolomé RA, Gálvez BG, Longo N, Baleux F, Van Muijen GN, Sánchez-Mateos P, Arroyo AG, Teixidó J.

Cancer Res. 2004 Apr 1;64(7):2534-43.


Rapid up-regulation of alpha4 integrin-mediated leukocyte adhesion by transforming growth factor-beta1.

Bartolomé RA, Sanz-Rodríguez F, Robledo MM, Hidalgo A, Teixidó J.

Mol Biol Cell. 2003 Jan;14(1):54-66.


Expression of functional chemokine receptors CXCR3 and CXCR4 on human melanoma cells.

Robledo MM, Bartolome RA, Longo N, Rodríguez-Frade JM, Mellado M, Longo I, van Muijen GN, Sánchez-Mateos P, Teixidó J.

J Biol Chem. 2001 Nov 30;276(48):45098-105. Epub 2001 Sep 24.

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