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Items: 39

1.

De novo coiled-coil peptides as scaffolds for disrupting protein-protein interactions.

Fletcher JM, Horner KA, Bartlett GJ, Rhys GG, Wilson AJ, Woolfson DN.

Chem Sci. 2018 Aug 7;9(39):7656-7665. doi: 10.1039/c8sc02643b. eCollection 2018 Oct 21.

2.

De Novo-Designed α-Helical Barrels as Receptors for Small Molecules.

Thomas F, Dawson WM, Lang EJM, Burton AJ, Bartlett GJ, Rhys GG, Mulholland AJ, Woolfson DN.

ACS Synth Biol. 2018 Jul 20;7(7):1808-1816. doi: 10.1021/acssynbio.8b00225. Epub 2018 Jul 10.

PMID:
29944338
3.

Applying graph theory to protein structures: an Atlas of coiled coils.

Heal JW, Bartlett GJ, Wood CW, Thomson AR, Woolfson DN.

Bioinformatics. 2018 Oct 1;34(19):3316-3323. doi: 10.1093/bioinformatics/bty347.

4.

Conformational Dynamics of Asparagine at Coiled-Coil Interfaces.

Thomas F, Niitsu A, Oregioni A, Bartlett GJ, Woolfson DN.

Biochemistry. 2017 Dec 19;56(50):6544-6554. doi: 10.1021/acs.biochem.7b00848. Epub 2017 Dec 5.

5.

Toward a Soluble Model System for the Amyloid State.

Thomas NC, Bartlett GJ, Woolfson DN, Gellman SH.

J Am Chem Soc. 2017 Nov 22;139(46):16434-16437. doi: 10.1021/jacs.7b07225. Epub 2017 Nov 8.

6.

Miniprotein Design: Past, Present, and Prospects.

Baker EG, Bartlett GJ, Porter Goff KL, Woolfson DN.

Acc Chem Res. 2017 Sep 19;50(9):2085-2092. doi: 10.1021/acs.accounts.7b00186. Epub 2017 Aug 23.

PMID:
28832117
7.

How do miniproteins fold?

Woolfson DN, Baker EG, Bartlett GJ.

Science. 2017 Jul 14;357(6347):133-134. doi: 10.1126/science.aan6864. No abstract available.

PMID:
28706028
8.

ISAMBARD: an open-source computational environment for biomolecular analysis, modelling and design.

Wood CW, Heal JW, Thomson AR, Bartlett GJ, Ibarra AÁ, Brady RL, Sessions RB, Woolfson DN.

Bioinformatics. 2017 Oct 1;33(19):3043-3050. doi: 10.1093/bioinformatics/btx352.

9.

Engineering protein stability with atomic precision in a monomeric miniprotein.

Baker EG, Williams C, Hudson KL, Bartlett GJ, Heal JW, Porter Goff KL, Sessions RB, Crump MP, Woolfson DN.

Nat Chem Biol. 2017 Jul;13(7):764-770. doi: 10.1038/nchembio.2380. Epub 2017 May 22.

10.

Characterization of long and stable de novo single alpha-helix domains provides novel insight into their stability.

Wolny M, Batchelor M, Bartlett GJ, Baker EG, Kurzawa M, Knight PJ, Dougan L, Woolfson DN, Paci E, Peckham M.

Sci Rep. 2017 Mar 13;7:44341. doi: 10.1038/srep44341.

11.

N@a and N@d: Oligomer and Partner Specification by Asparagine in Coiled-Coil Interfaces.

Fletcher JM, Bartlett GJ, Boyle AL, Danon JJ, Rush LE, Lupas AN, Woolfson DN.

ACS Chem Biol. 2017 Feb 17;12(2):528-538. doi: 10.1021/acschembio.6b00935. Epub 2017 Jan 9.

PMID:
28026921
12.

On the satisfaction of backbone-carbonyl lone pairs of electrons in protein structures.

Bartlett GJ, Woolfson DN.

Protein Sci. 2016 Apr;25(4):887-97. doi: 10.1002/pro.2896. Epub 2016 Feb 25.

13.

Carbohydrate-Aromatic Interactions in Proteins.

Hudson KL, Bartlett GJ, Diehl RC, Agirre J, Gallagher T, Kiessling LL, Woolfson DN.

J Am Chem Soc. 2015 Dec 9;137(48):15152-60. doi: 10.1021/jacs.5b08424. Epub 2015 Nov 30.

14.

Corrigendum: Local and macroscopic electrostatic interactions in single α-helices.

Baker EG, Bartlett GJ, Crump MP, Sessions RB, Linden N, Faul CF, Woolfson DN.

Nat Chem Biol. 2015 Sep;11(9):741. doi: 10.1038/nchembio0915-741e. No abstract available.

PMID:
26284676
15.

De novo protein design: how do we expand into the universe of possible protein structures?

Woolfson DN, Bartlett GJ, Burton AJ, Heal JW, Niitsu A, Thomson AR, Wood CW.

Curr Opin Struct Biol. 2015 Aug;33:16-26. doi: 10.1016/j.sbi.2015.05.009. Epub 2015 Jun 18. Review.

16.

Local and macroscopic electrostatic interactions in single α-helices.

Baker EG, Bartlett GJ, Crump MP, Sessions RB, Linden N, Faul CF, Woolfson DN.

Nat Chem Biol. 2015 Mar;11(3):221-8. doi: 10.1038/nchembio.1739. Epub 2015 Feb 9. Erratum in: Nat Chem Biol. 2015 Sep;11(9):741.

17.

Computational design of water-soluble α-helical barrels.

Thomson AR, Wood CW, Burton AJ, Bartlett GJ, Sessions RB, Brady RL, Woolfson DN.

Science. 2014 Oct 24;346(6208):485-8. doi: 10.1126/science.1257452.

18.

CCBuilder: an interactive web-based tool for building, designing and assessing coiled-coil protein assemblies.

Wood CW, Bruning M, Ibarra AÁ, Bartlett GJ, Thomson AR, Sessions RB, Brady RL, Woolfson DN.

Bioinformatics. 2014 Nov 1;30(21):3029-35. doi: 10.1093/bioinformatics/btu502. Epub 2014 Jul 26.

19.

Signatures of n→π* interactions in proteins.

Newberry RW, Bartlett GJ, VanVeller B, Woolfson DN, Raines RT.

Protein Sci. 2014 Mar;23(3):284-8. doi: 10.1002/pro.2413.

20.

Interplay of hydrogen bonds and n→π* interactions in proteins.

Bartlett GJ, Newberry RW, VanVeller B, Raines RT, Woolfson DN.

J Am Chem Soc. 2013 Dec 11;135(49):18682-8. doi: 10.1021/ja4106122. Epub 2013 Dec 3.

21.

A basis set of de novo coiled-coil peptide oligomers for rational protein design and synthetic biology.

Fletcher JM, Boyle AL, Bruning M, Bartlett GJ, Vincent TL, Zaccai NR, Armstrong CT, Bromley EH, Booth PJ, Brady RL, Thomson AR, Woolfson DN.

ACS Synth Biol. 2012 Jun 15;1(6):240-50. doi: 10.1021/sb300028q. Epub 2012 May 14.

PMID:
23651206
22.

Strong contributions from vertical triads to helix-partner preferences in parallel coiled coils.

Steinkruger JD, Bartlett GJ, Woolfson DN, Gellman SH.

J Am Chem Soc. 2012 Sep 26;134(38):15652-5. Epub 2012 Sep 13.

23.

Squaring the circle in peptide assembly: from fibers to discrete nanostructures by de novo design.

Boyle AL, Bromley EH, Bartlett GJ, Sessions RB, Sharp TH, Williams CL, Curmi PM, Forde NR, Linke H, Woolfson DN.

J Am Chem Soc. 2012 Sep 19;134(37):15457-67. Epub 2012 Sep 6.

PMID:
22917063
24.

New currency for old rope: from coiled-coil assemblies to α-helical barrels.

Woolfson DN, Bartlett GJ, Bruning M, Thomson AR.

Curr Opin Struct Biol. 2012 Aug;22(4):432-41. doi: 10.1016/j.sbi.2012.03.002. Epub 2012 Mar 23. Review.

PMID:
22445228
25.

The d'--d--d' vertical triad is less discriminating than the a'--a--a' vertical triad in the antiparallel coiled-coil dimer motif.

Steinkruger JD, Bartlett GJ, Hadley EB, Fay L, Woolfson DN, Gellman SH.

J Am Chem Soc. 2012 Feb 8;134(5):2626-33. doi: 10.1021/ja208855x. Epub 2012 Jan 31.

26.

A de novo peptide hexamer with a mutable channel.

Zaccai NR, Chi B, Thomson AR, Boyle AL, Bartlett GJ, Bruning M, Linden N, Sessions RB, Booth PJ, Brady RL, Woolfson DN.

Nat Chem Biol. 2011 Oct 30;7(12):935-41. doi: 10.1038/nchembio.692.

27.

Designed coiled coils promote folding of a recombinant bacterial collagen.

Yoshizumi A, Fletcher JM, Yu Z, Persikov AV, Bartlett GJ, Boyle AL, Vincent TL, Woolfson DN, Brodsky B.

J Biol Chem. 2011 May 20;286(20):17512-20. doi: 10.1074/jbc.M110.217364. Epub 2011 Mar 28.

28.

n-->pi* interactions in proteins.

Bartlett GJ, Choudhary A, Raines RT, Woolfson DN.

Nat Chem Biol. 2010 Aug;6(8):615-20. doi: 10.1038/nchembio.406. Epub 2010 Jul 11.

29.

Prediction of protein structure from ideal forms.

Taylor WR, Bartlett GJ, Chelliah V, Klose D, Lin K, Sheldon T, Jonassen I.

Proteins. 2008 Mar;70(4):1610-9. doi: 10.1002/prot.21913.

PMID:
18175329
31.

MACiE (Mechanism, Annotation and Classification in Enzymes): novel tools for searching catalytic mechanisms.

Holliday GL, Almonacid DE, Bartlett GJ, O'Boyle NM, Torrance JW, Murray-Rust P, Mitchell JB, Thornton JM.

Nucleic Acids Res. 2007 Jan;35(Database issue):D515-20. Epub 2006 Nov 1.

32.

MACiE: a database of enzyme reaction mechanisms.

Holliday GL, Bartlett GJ, Almonacid DE, O'Boyle NM, Murray-Rust P, Thornton JM, Mitchell JB.

Bioinformatics. 2005 Dec 1;21(23):4315-6. Epub 2005 Sep 27.

33.

Effective function annotation through catalytic residue conservation.

George RA, Spriggs RV, Bartlett GJ, Gutteridge A, MacArthur MW, Porter CT, Al-Lazikani B, Thornton JM, Swindells MB.

Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12299-304. Epub 2005 Jul 21.

34.

Using a library of structural templates to recognise catalytic sites and explore their evolution in homologous families.

Torrance JW, Bartlett GJ, Porter CT, Thornton JM.

J Mol Biol. 2005 Apr 1;347(3):565-81.

PMID:
15755451
35.

The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data.

Porter CT, Bartlett GJ, Thornton JM.

Nucleic Acids Res. 2004 Jan 1;32(Database issue):D129-33.

36.

Catalysing new reactions during evolution: economy of residues and mechanism.

Bartlett GJ, Borkakoti N, Thornton JM.

J Mol Biol. 2003 Aug 22;331(4):829-60.

PMID:
12909013
37.

Using a neural network and spatial clustering to predict the location of active sites in enzymes.

Gutteridge A, Bartlett GJ, Thornton JM.

J Mol Biol. 2003 Jul 18;330(4):719-34.

PMID:
12850142
38.

Inferring protein function from structure.

Bartlett GJ, Todd AE, Thornton JM.

Methods Biochem Anal. 2003;44:387-407. Review. No abstract available.

PMID:
12647396
39.

Analysis of catalytic residues in enzyme active sites.

Bartlett GJ, Porter CT, Borkakoti N, Thornton JM.

J Mol Biol. 2002 Nov 15;324(1):105-21.

PMID:
12421562

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