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Items: 15

1.

Mirvetuximab Soravtansine (IMGN853), a Folate Receptor Alpha-Targeting Antibody-Drug Conjugate, Potentiates the Activity of Standard of Care Therapeutics in Ovarian Cancer Models.

Ponte JF, Ab O, Lanieri L, Lee J, Coccia J, Bartle LM, Themeles M, Zhou Y, Pinkas J, Ruiz-Soto R.

Neoplasia. 2016 Dec;18(12):775-784. doi: 10.1016/j.neo.2016.11.002. Epub 2016 Nov 25.

2.

IMGN853, a Folate Receptor-α (FRα)-Targeting Antibody-Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FRα-Expressing Tumors.

Ab O, Whiteman KR, Bartle LM, Sun X, Singh R, Tavares D, LaBelle A, Payne G, Lutz RJ, Pinkas J, Goldmacher VS, Chittenden T, Lambert JM.

Mol Cancer Ther. 2015 Jul;14(7):1605-13. doi: 10.1158/1535-7163.MCT-14-1095. Epub 2015 Apr 22.

3.

SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies.

Deckert J, Wetzel MC, Bartle LM, Skaletskaya A, Goldmacher VS, Vallée F, Zhou-Liu Q, Ferrari P, Pouzieux S, Lahoute C, Dumontet C, Plesa A, Chiron M, Lejeune P, Chittenden T, Park PU, Blanc V.

Clin Cancer Res. 2014 Sep 1;20(17):4574-83. doi: 10.1158/1078-0432.CCR-14-0695. Epub 2014 Jul 1.

4.

Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria.

Arnoult D, Bartle LM, Skaletskaya A, Poncet D, Zamzami N, Park PU, Sharpe J, Youle RJ, Goldmacher VS.

Proc Natl Acad Sci U S A. 2004 May 25;101(21):7988-93. Epub 2004 May 17.

5.

An anti-apoptotic viral protein that recruits Bax to mitochondria.

Poncet D, Larochette N, Pauleau AL, Boya P, Jalil AA, Cartron PF, Vallette F, Schnebelen C, Bartle LM, Skaletskaya A, Boutolleau D, Martinou JC, Goldmacher VS, Kroemer G, Zamzami N.

J Biol Chem. 2004 May 21;279(21):22605-14. Epub 2004 Mar 5.

6.

Tumor-specific novel taxoid-monoclonal antibody conjugates.

Ojima I, Geng X, Wu X, Qu C, Borella CP, Xie H, Wilhelm SD, Leece BA, Bartle LM, Goldmacher VS, Chari RV.

J Med Chem. 2002 Dec 19;45(26):5620-3.

PMID:
12477344
7.

The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal.

Vieira HL, Belzacq AS, Haouzi D, Bernassola F, Cohen I, Jacotot E, Ferri KF, El Hamel C, Bartle LM, Melino G, Brenner C, Goldmacher V, Kroemer G.

Oncogene. 2001 Jul 19;20(32):4305-16.

PMID:
11466611
8.

A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activation.

Skaletskaya A, Bartle LM, Chittenden T, McCormick AL, Mocarski ES, Goldmacher VS.

Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7829-34. Epub 2001 Jun 26.

9.

The sequence and antiapoptotic functional domains of the human cytomegalovirus UL37 exon 1 immediate early protein are conserved in multiple primary strains.

Hayajneh WA, Colberg-Poley AM, Skaletskaya A, Bartle LM, Lesperance MM, Contopoulos-Ioannidis DG, Kedersha NL, Goldmacher VS.

Virology. 2001 Jan 5;279(1):233-40.

10.

A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2.

Goldmacher VS, Bartle LM, Skaletskaya A, Dionne CA, Kedersha NL, Vater CA, Han JW, Lutz RJ, Watanabe S, Cahir McFarland ED, Kieff ED, Mocarski ES, Chittenden T.

Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12536-41.

11.
12.

Ricin A chain can be chemically cross-linked to the mammalian ribosomal proteins L9 and L10e.

Vater CA, Bartle LM, Leszyk JD, Lambert JM, Goldmacher VS.

J Biol Chem. 1995 May 26;270(21):12933-40.

13.

Characterization of antibody binding to cell surface antigens using a plasma membrane-bound plate assay.

Vater CA, Reid K, Bartle LM, Goldmacher VS.

Anal Biochem. 1995 Jan 1;224(1):39-50.

PMID:
7535987
14.

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